標(biāo)題: Titlebook: Diseases of DNA Repair; Shamim I. Ahmad Book 2010 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Sci [打印本頁(yè)] 作者: 到來(lái) 時(shí)間: 2025-3-21 20:09
書(shū)目名稱Diseases of DNA Repair影響因子(影響力)
書(shū)目名稱Diseases of DNA Repair影響因子(影響力)學(xué)科排名
書(shū)目名稱Diseases of DNA Repair網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Diseases of DNA Repair網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Diseases of DNA Repair被引頻次
書(shū)目名稱Diseases of DNA Repair被引頻次學(xué)科排名
書(shū)目名稱Diseases of DNA Repair年度引用
書(shū)目名稱Diseases of DNA Repair年度引用學(xué)科排名
書(shū)目名稱Diseases of DNA Repair讀者反饋
書(shū)目名稱Diseases of DNA Repair讀者反饋學(xué)科排名
作者: 殖民地 時(shí)間: 2025-3-21 22:15 作者: 耐寒 時(shí)間: 2025-3-22 00:39 作者: 貧困 時(shí)間: 2025-3-22 07:46 作者: Spirometry 時(shí)間: 2025-3-22 11:32
Per ?hlin: The Master of Swedish Animationathway, but not in the global genome NER pathway. Fourteen cases so far described as COFS syndrome have been studied at the molecular levels. All mutations have been found in Cockayne syndrome gene, ., xeroderma pigmentosum genes, . and . and . gene involved in the transcription-coupled NER p作者: Evolve 時(shí)間: 2025-3-22 13:20
Amyotrophic Lateral Sclerosis,isms behind the disease. We discuss the current understanding and controversies of how mutations in Cu,ZnSOD may cause the disease. We also focus on the recent discovery that mutations in either TDP-43 or FUS/TLS, which are both involved in DNA/RNA synthesis, are likely the cause behind many cases of ALS that are not linked to Cu作者: Evolve 時(shí)間: 2025-3-22 20:29 作者: 土坯 時(shí)間: 2025-3-22 22:19
Cerebro-Oculo-Facio-Skeletal Syndrome,athway, but not in the global genome NER pathway. Fourteen cases so far described as COFS syndrome have been studied at the molecular levels. All mutations have been found in Cockayne syndrome gene, ., xeroderma pigmentosum genes, . and . and . gene involved in the transcription-coupled NER p作者: NOTCH 時(shí)間: 2025-3-23 04:36 作者: Ganglion-Cyst 時(shí)間: 2025-3-23 06:34
Spinocerebellar Ataxia with Axonal Neuropathy,lent reaction intermediate can form during the repair of stalled topoisomerase I-DNA adducts or oxidatively damaged bases at the 3′ end of the DNA at a strand break. However, our current understanding of the biology of Tdp1 function in humans is limited and does not allow us to fully elucidate the disease mec作者: Stagger 時(shí)間: 2025-3-23 12:23
Book 2010 cover all the DNA repair deficient diseases in this volume, hence diseases such as Bloom’s syndrome, Werner’s syndrome, Nijmegen breakage syndrome, ataxia telangiectasia?like disorder, RA D 50 deficiency, RIDDLE syndrome and others will be presented in a forthcoming volume.作者: 商談 時(shí)間: 2025-3-23 17:17
Swarm Coordination and Control Problemsnal transport and altered synaptic transmission culminate in neuronal dysfianction and death. There is currently no way ofpreventing or slowing down the disease progression and death usually occurs at about 20 years after dia作者: Fester 時(shí)間: 2025-3-23 20:38
Pierre Ségur,M.-C. Bordage,M. Yousfial step of neurodegenerative process, which is followed by several molecular events such as transcriptional dysregulation, axonal transport disruption and mitochondrial dysfunction. Results of animal studies suggest that androgen deprivation and activation of protein quality control systems are potential therapies fo作者: POWER 時(shí)間: 2025-3-24 01:19
https://doi.org/10.1007/978-0-230-80255-1ch as double strand DNA break repair, chromatin remodeling and maintaining genomic stability. Here, we will discuss the biology of cohesin and its associated factors, with emphasis on the clinical manifestations of CdLS and mechanistic studies of the CdLS related pr作者: 諄諄教誨 時(shí)間: 2025-3-24 05:04 作者: 積極詞匯 時(shí)間: 2025-3-24 07:21 作者: 概觀 時(shí)間: 2025-3-24 14:10
The Policy of Active Neutralityunction. This results in impaired V(D)J recombination, the essential rejoining process in T- and B-cell development, in whose ligase IV plays the key role. As a consequence, patients with LIG4 syndrome frequently develop multiple immune abnormalities, clinically overlapping with severe combined immunodeficiency sy作者: 賠償 時(shí)間: 2025-3-24 15:37
,Huntington’s Disease,nal transport and altered synaptic transmission culminate in neuronal dysfianction and death. There is currently no way ofpreventing or slowing down the disease progression and death usually occurs at about 20 years after dia作者: extinct 時(shí)間: 2025-3-24 20:41 作者: Tartar 時(shí)間: 2025-3-25 02:45 作者: AGONY 時(shí)間: 2025-3-25 04:42
Familial Cutaneous Melanoma,ancies—most notably pancreatic carcinoma. A much smaller number of families have germline mutations in the . gene on chromosome 12q14, encoding a cyclin dependent kinase which normally interacts with p16INK4A. The management of families with hereditary melanoma is dis作者: Sciatica 時(shí)間: 2025-3-25 08:15 作者: 嫻熟 時(shí)間: 2025-3-25 12:11 作者: 伸展 時(shí)間: 2025-3-25 18:59 作者: 不透明性 時(shí)間: 2025-3-25 22:30 作者: Innocence 時(shí)間: 2025-3-26 00:59 作者: nitric-oxide 時(shí)間: 2025-3-26 04:25 作者: 混沌 時(shí)間: 2025-3-26 12:24 作者: 高射炮 時(shí)間: 2025-3-26 15:14 作者: enormous 時(shí)間: 2025-3-26 19:03 作者: 定點(diǎn) 時(shí)間: 2025-3-26 21:27 作者: Ostrich 時(shí)間: 2025-3-27 03:26
Swarm Stability and Optimizationeocortex and hippocampus. AD is the most common form of dementia in the elderly people. Apart from the neuronal loss, the pathological hallmarks are extracellular senile plaques containing the peptide beta-amyloid (Aβ) and neurofibrillary tangles. The Aβ cascade hypothesis remains the main pathogene作者: minaret 時(shí)間: 2025-3-27 07:49 作者: 試驗(yàn) 時(shí)間: 2025-3-27 11:25
Pierre Ségur,M.-C. Bordage,M. Yousfi The cause of this disease is the expansion of a trinucleotide CAG repeat, which encodes the polyglutamine tract, within the first exon of the . (.) gene. SBMA exclusively occurs in adult males, whereas both heterozygous and homozygous females are usually asymptomatic. Lower motor neurons in the ant作者: Limerick 時(shí)間: 2025-3-27 16:46
M. T. Elford,A. Ernest,S. C. Haydonhe tyrosyl-DNA phosphodiesterase . gene. Functional and genetic studies suggest that this mutation, which disrupts the active site of the Tdp1 enzyme, causes disease by a combination of decreased catalytic activity and stabilization of the normally transient covalent Tdp1-DNA intermediate. This cova作者: 雄偉 時(shí)間: 2025-3-27 20:50 作者: Lice692 時(shí)間: 2025-3-27 23:05
https://doi.org/10.1007/978-981-16-4357-6caused by a wide variety of reasons, including defects in repair of light-induced DNA lesions, the interaction of certain chemicals or medications with sunlight to produce toxic mediators and photo-induced immune reactions. In this chapter we will describe photodermatoses that are associated with he作者: PET-scan 時(shí)間: 2025-3-28 03:45 作者: 興奮過(guò)度 時(shí)間: 2025-3-28 08:24
https://doi.org/10.1007/978-0-230-80255-1facial features, growth and mental retardation, upper limb defects, hirsutism, gastrointestinal and other visceral system involvement. Heterozygous mutations in the cohesin regulator, ., or the cohesin structural components . and ., have been identified in approximately 65% of individuals with CdLS.作者: BLOT 時(shí)間: 2025-3-28 12:12
The Origins of Sweden’s Neutrality to facilitate surgical intervention, reduce the rate of local recurrence and improve overall outcomes in patients suffering from this malignancy. However, this modality results in a wide range of clinical responses. In many cases, a pathological complete response is achieved, while in others, recei作者: 詼諧 時(shí)間: 2025-3-28 16:14
Evolution of the Policy of Neutralitywith familial melanoma harbor germline mutations in the . gene, located on chromosome 9p21, which encodes two different proteins, p16INK4 and p14ARF, both involved in regulation of cell cycle progression and induction of senescence. In different populations several recurring . founder mutations have作者: 規(guī)范要多 時(shí)間: 2025-3-28 21:44 作者: textile 時(shí)間: 2025-3-29 02:37
End of War and Beginning of Peaceomplex molecular events that underlie antibody maturation in humans. The Activation-induced cytidine deaminase (AID)-deficiency, characterized by a defect in Class Switch Recombination (CSR) and somatic hypermutation, has revealed the master role of this molecule in the induction of DNA damage, the 作者: sclera 時(shí)間: 2025-3-29 03:14
The Policy of Active Neutralityogically, patients affected with this syndrome are characterized by microcephaly, unusual facial features, growth retardation, developmental delay, skin anomalies and are typically pancytopenic. The disease leads to acute radiosensitivity, immunodeficiency and bone marrow abnormalities. LIG4 syndrom作者: certain 時(shí)間: 2025-3-29 08:11
Per ?hlin: The Master of Swedish Animationomas and one or more low-grade visceral malignancies, with or without colonic polyps, in the absence of other predisposing factors. This chapter presents a review of the principal clinical and genetic findings in this syndrome and discusses its relation with Lynch sy作者: 擴(kuò)大 時(shí)間: 2025-3-29 12:11 作者: craving 時(shí)間: 2025-3-29 18:28 作者: 諂媚于性 時(shí)間: 2025-3-29 20:31 作者: Alpha-Cells 時(shí)間: 2025-3-30 00:59
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/e/image/281279.jpg作者: 雪白 時(shí)間: 2025-3-30 05:56
Triple-A Syndrome,t is a rare disease and inherited by autosomal recessive pattern. Allgrove syndrome is characterized by mutation(s) in AAAS gene, located on chromosome 12q13, that codes for ALADIN protein. Most mutations produce a truncated protein, although missense and point-mutations have also been reported. Som作者: Herd-Immunity 時(shí)間: 2025-3-30 12:16
Amyotrophic Lateral Sclerosis,muscle paralysis that is fatal. There is no available cure and current therapies only provide minimal benefit at best. The disease is predominantly sporadic and until very recently only the Cu,Zn superoxide dismutase (Cu,ZnSOD), which is involved in a small number of sporadic cases and a larger comp作者: 骨 時(shí)間: 2025-3-30 14:01 作者: 焦慮 時(shí)間: 2025-3-30 20:03 作者: CRUDE 時(shí)間: 2025-3-30 23:50 作者: 偏見(jiàn) 時(shí)間: 2025-3-31 00:50 作者: 摻和 時(shí)間: 2025-3-31 06:26 作者: 支形吊燈 時(shí)間: 2025-3-31 12:17
Tuberous Sclerosis Complex and DNA Repair,ng renal angiomyolipomas, cardiac rhabdomyomas and subependymal giant cell astrocytomas. TSC causes disabling neurologic disorders, including epilepsy, mental retardation and autism. Brain lesions, including subependymal and subcortical hamartomas, have also been reported in TSC patients. TSC is ass作者: 我悲傷 時(shí)間: 2025-3-31 15:21
Hereditary Photodermatoses,caused by a wide variety of reasons, including defects in repair of light-induced DNA lesions, the interaction of certain chemicals or medications with sunlight to produce toxic mediators and photo-induced immune reactions. In this chapter we will describe photodermatoses that are associated with he作者: duplicate 時(shí)間: 2025-3-31 17:58
Trichothiodystrophy: Photosensitive, TTD-P, TTD, Tay Syndrome, which any or every organ in the body may be affected..–. Neuroectodermal derived tissues are particularly likely to be involved. This term was introduced by Price et al in 1980 to designate patients with sulfur-deficient brittle hair, which they recognized as a marker for this complex disease and d作者: 顯微鏡 時(shí)間: 2025-3-31 22:57
Cornelia de Lange Syndrome,facial features, growth and mental retardation, upper limb defects, hirsutism, gastrointestinal and other visceral system involvement. Heterozygous mutations in the cohesin regulator, ., or the cohesin structural components . and ., have been identified in approximately 65% of individuals with CdLS.作者: 元音 時(shí)間: 2025-4-1 04:23
Rectal Cancer and Importance of Chemoradiation in the Treatment, to facilitate surgical intervention, reduce the rate of local recurrence and improve overall outcomes in patients suffering from this malignancy. However, this modality results in a wide range of clinical responses. In many cases, a pathological complete response is achieved, while in others, recei作者: Strength 時(shí)間: 2025-4-1 06:58 作者: 小說(shuō) 時(shí)間: 2025-4-1 13:58
Primary Immunodeficiency Syndromes,ty. Defects in these pathways can lead to replication errors, loss or rearrangement of genomic material, mutation or cancer and eventual death. The creation of many diverse lymphocyte receptors to identify potential pathogens has evolved by breaking and randomly resorting the gene segments coding fo作者: ETCH 時(shí)間: 2025-4-1 14:49
Inherited Defects of Immunoglobulin Class Switch Recombination,omplex molecular events that underlie antibody maturation in humans. The Activation-induced cytidine deaminase (AID)-deficiency, characterized by a defect in Class Switch Recombination (CSR) and somatic hypermutation, has revealed the master role of this molecule in the induction of DNA damage, the 作者: Kidnap 時(shí)間: 2025-4-1 21:05
Ligase IV Syndrome,ogically, patients affected with this syndrome are characterized by microcephaly, unusual facial features, growth retardation, developmental delay, skin anomalies and are typically pancytopenic. The disease leads to acute radiosensitivity, immunodeficiency and bone marrow abnormalities. LIG4 syndrom作者: 針葉類的樹(shù) 時(shí)間: 2025-4-2 01:54
