標題: Titlebook: Directed Drug Delivery; A Multidisciplinary Ronald T. Borchardt,Arnold J. Repta,Valentino J. S Book 1985 The Humana Press Inc. 1985 bioche [打印本頁] 作者: 多話 時間: 2025-3-21 18:16
書目名稱Directed Drug Delivery影響因子(影響力)
書目名稱Directed Drug Delivery影響因子(影響力)學科排名
書目名稱Directed Drug Delivery網(wǎng)絡(luò)公開度
書目名稱Directed Drug Delivery網(wǎng)絡(luò)公開度學科排名
書目名稱Directed Drug Delivery被引頻次
書目名稱Directed Drug Delivery被引頻次學科排名
書目名稱Directed Drug Delivery年度引用
書目名稱Directed Drug Delivery年度引用學科排名
書目名稱Directed Drug Delivery讀者反饋
書目名稱Directed Drug Delivery讀者反饋學科排名
作者: 邊緣帶來墨水 時間: 2025-3-21 23:14 作者: 愚笨 時間: 2025-3-22 00:31 作者: 天真 時間: 2025-3-22 07:26 作者: 無政府主義者 時間: 2025-3-22 09:18 作者: 軍械庫 時間: 2025-3-22 15:04 作者: 軍械庫 時間: 2025-3-22 19:25
Müfit Bahadir,Harun Parlar,Michael Spitellerrs where the basic excipient is neutralized by the external medium or by using acidic excipients (Heller, 1980) incorporated into the typically highly hydrophobic matrix. In this latter case, surface erosion takes place only in the surface layer where the excipient is exposed to water.作者: CURB 時間: 2025-3-22 21:52
Biodegradable Poly(Ortho Esters) as Drug Delivery Formsrs where the basic excipient is neutralized by the external medium or by using acidic excipients (Heller, 1980) incorporated into the typically highly hydrophobic matrix. In this latter case, surface erosion takes place only in the surface layer where the excipient is exposed to water.作者: HUMID 時間: 2025-3-23 01:47 作者: antedate 時間: 2025-3-23 06:08 作者: ALIBI 時間: 2025-3-23 12:22
Gastrointestinal Barrier to Oral Drug Deliveryivery largely unexplored until active lead compounds are tested in whole animal models. Questions of rate and extent of absorption, degree of pre-systemic metabolism and optimal delivery pattern are critical to the success of a therapeutic agent and deserve important attention in the development of new drug entities.作者: travail 時間: 2025-3-23 15:17 作者: Mendicant 時間: 2025-3-23 21:44
Pharmaceutics and the Evolving Technology of Drug Delivery-A Perspective and has had a significant impact on my career. It is also fitting that the topic of drug delivery has been selected to honor Professor Higuchi since his entire career reflects an interest in and impact on the broad issue of drug delivery.作者: oblique 時間: 2025-3-23 22:22 作者: 膠狀 時間: 2025-3-24 03:30 作者: 藕床生厭倦 時間: 2025-3-24 08:46 作者: 整潔 時間: 2025-3-24 13:46 作者: diathermy 時間: 2025-3-24 15:34
Müfit Bahadir,Harun Parlar,Michael Spitellerg-effect relationships. In combination with a pharmacokinetic model and suitable delay functions, such models are capable of simulating the complete time course of drug action ... The predictive potential of the pharmacokinetic-pharmacodynamic models should prove useful in evaluating pharmaceutical formulations with controlled drug delivery.作者: 提名的名單 時間: 2025-3-24 20:18
Müfit Bahadir,Harun Parlar,Michael Spiteller of dextran-conjugated mitomycin C obtained in our labolatory because they serve nicely to illustrate important considerations in the design of macromolecular conjugate and appear be practical for use in human cancer chemotherapy.作者: 暴露他抗議 時間: 2025-3-24 23:31
Molecular Mechanisms of Drug Action and Pharmacokinetic-Pharmacodynamic Modelsg-effect relationships. In combination with a pharmacokinetic model and suitable delay functions, such models are capable of simulating the complete time course of drug action ... The predictive potential of the pharmacokinetic-pharmacodynamic models should prove useful in evaluating pharmaceutical formulations with controlled drug delivery.作者: GROG 時間: 2025-3-25 03:31
Macromolecules as Drug Delivery Systems of dextran-conjugated mitomycin C obtained in our labolatory because they serve nicely to illustrate important considerations in the design of macromolecular conjugate and appear be practical for use in human cancer chemotherapy.作者: Narcissist 時間: 2025-3-25 09:52
Book 1985ansas on October 17-19, 1984. The purpose of the sym- posium and this book is to focus on the multidisciplinary nature of drug delivery. Development of a successful drug delivery system re- quires contributions from various scientific disciplines, including pharmaceutical chemistry, analytical chemi作者: 傳授知識 時間: 2025-3-25 14:09
Müfit Bahadir,Harun Parlar,Michael SpitellerAs illustrated by the preceding papers in this symposium, contemporary technology provides clinicians with an exciting array of drug delivery systems. However, the selection of the most appropriate delivery system for any particular drug continues to be based on:作者: 錯 時間: 2025-3-25 16:37
New Drug Delivery Systems: Physico-Chemical ConsiderationsAs illustrated by the preceding papers in this symposium, contemporary technology provides clinicians with an exciting array of drug delivery systems. However, the selection of the most appropriate delivery system for any particular drug continues to be based on:作者: 有毒 時間: 2025-3-25 21:40 作者: yohimbine 時間: 2025-3-26 01:01 作者: 隱藏 時間: 2025-3-26 06:16 作者: Halfhearted 時間: 2025-3-26 09:35 作者: BORE 時間: 2025-3-26 14:04
The Dermal Barrier to Local and Systemic Drug Deliveryuse my assignment is to talk about drug transport in skin and my first job after receiving my Ph.D. in 1956 was to study factors influencing drug transport across skin at the University of Wisconsin under a Defense Department contract directed by Tak and Dale Wurster.作者: 我不死扛 時間: 2025-3-26 18:21
https://doi.org/10.1007/BFb0045595as had on the pharmaceutical sciences, by virtue of his own research activities, and that of students he has trained, he is also my academic godfather and has had a significant impact on my career. It is also fitting that the topic of drug delivery has been selected to honor Professor Higuchi since 作者: 卡死偷電 時間: 2025-3-27 00:16 作者: 傲慢人 時間: 2025-3-27 02:18 作者: Ingratiate 時間: 2025-3-27 07:09
Müfit Bahadir,Harun Parlar,Michael Spitellercollaboration that continued for over 4 years between 1969 and 1972. Higuchi’s laboratory played a major role in developing the first two therapeutic system products, which have embodied a number of pharmaceutical “firsts”. These are the pilocarpine ocular therapeutic system and the progesterone ute作者: forager 時間: 2025-3-27 10:04
Müfit Bahadir,Harun Parlar,Michael Spitellergy and biochemical defects responsible for disease processes the drug industry has moved from large scale screening operations to much more rational approaches to drug design in which active molecules are synthesized and tested on the basis of .. measurements of interactions with specific receptors 作者: 圖畫文字 時間: 2025-3-27 14:15
Müfit Bahadir,Harun Parlar,Michael Spitellers in drug distribution only to the surface of the brain. Another approach to circumventing the BBB involves drug latentiation or the conversion of water soluble substances to lipid soluble compounds. This approach portends a vast promise for the neuropharmaceutical industry, which has yet to be real作者: GRILL 時間: 2025-3-27 19:54
Müfit Bahadir,Harun Parlar,Michael Spitelleruse my assignment is to talk about drug transport in skin and my first job after receiving my Ph.D. in 1956 was to study factors influencing drug transport across skin at the University of Wisconsin under a Defense Department contract directed by Tak and Dale Wurster.作者: 脫水 時間: 2025-3-28 01:18
Müfit Bahadir,Harun Parlar,Michael Spitelleression is the basis for many systems that are even claimed to be new today. This development was a milestone in area of physical pharmacy and dosage form development. Tak has been a driving force in the field of pharmacy: he gave people a mission and has been a source of inspiration. I was a low tem作者: Seminar 時間: 2025-3-28 03:06 作者: Prostatism 時間: 2025-3-28 08:29
Müfit Bahadir,Harun Parlar,Michael Spiteller7.4, and become progressively more labile as the pH is lowered. A major rationale for developing this system was a need for a polymer capable of a wide variety of erosion rates and where erosion could be confined to the surface of a solid device. Then, any selected, constant release rate can be achi作者: endoscopy 時間: 2025-3-28 10:42
Müfit Bahadir,Harun Parlar,Michael Spiteller agents. Since active targeting such as antibody or receptor-mediated delivery will be mentioned in other chapters, discussions will be limited to the use of conjugates in which a drug is associated or covalently bound to a non-specific macro-molecular carrier. Emphasis will be placed on the results作者: Consequence 時間: 2025-3-28 17:58
Müfit Bahadir,Harun Parlar,Michael Spitellern with unique cell surface determinants was confined largely to immunology groups (Mason and Williams, 1980). As clinical applications appear practical these systems are likely to come increasingly under the purview of pharmacologists. The point of view of this paper is that the questions and tools 作者: 馬籠頭 時間: 2025-3-28 19:30
Müfit Bahadir,Harun Parlar,Michael Spitellerry the drug is attached to or associated with a ligand which recognizes a specific receptor on the surface of a target cell. The ligand can be a component of a phospholipid vesicle, e.g. liposome, a lipoprotein particle or a chemical derivative of a macromolecule, small peptide or oligosaccharide (F作者: 放氣 時間: 2025-3-29 02:43
Müfit Bahadir,Harun Parlar,Michael Spitellern. The concept is not new since compounds such as acetylsalicylic acid (aspirin), as a prodrug of salicylic acid, and methenamine, as a prodrug of formaldehyde, were discovered in the late 19th century. The term “pro-drug or “pro-agent” was first used by Albert (1958) who suggested that this approac作者: backdrop 時間: 2025-3-29 05:31 作者: MEN 時間: 2025-3-29 09:48 作者: innate 時間: 2025-3-29 12:11
Pharmacodynamic Considerations in the Development of New Drug Delivery Concepts correlations that have been defined, it is important to realize that the relationships are only meaningful at steady state or at a time when the ratio of the drug concentrations at the site of action and in plasma can be expected to remain constant over time; that is, during the terminal log-linear作者: Expand 時間: 2025-3-29 18:41 作者: cardiovascular 時間: 2025-3-29 19:43
Ronald T. Borchardt,Arnold J. Repta,Valentino J. S作者: Microaneurysm 時間: 2025-3-30 02:02
A survey of the experimental situation, correlations that have been defined, it is important to realize that the relationships are only meaningful at steady state or at a time when the ratio of the drug concentrations at the site of action and in plasma can be expected to remain constant over time; that is, during the terminal log-linear作者: Anthology 時間: 2025-3-30 04:17 作者: Hypopnea 時間: 2025-3-30 11:37
Book 1985cokineticists, pharmacologists, and clinicians involved in bio- logical evaluation of drug delivery systems. The volume should also be of interest to the analytical chemists who must provide technology to quantitcltively evaluate drug delivery. Additionally, this work will also interest the biochemi作者: Arthropathy 時間: 2025-3-30 14:28 作者: legitimate 時間: 2025-3-30 20:20
Pharmaceutics and the Evolving Technology of Drug Delivery-A Perspectiveas had on the pharmaceutical sciences, by virtue of his own research activities, and that of students he has trained, he is also my academic godfather and has had a significant impact on my career. It is also fitting that the topic of drug delivery has been selected to honor Professor Higuchi since 作者: 預測 時間: 2025-3-31 00:47
Pharmacodynamic Considerations in the Development of New Drug Delivery Conceptsis appropriate for the treatment of a disease state in a specific patient population is best instituted when one knows the plasma concentration which will maximize the efficacy of the drug and the level below which drug concentrations or amounts in the body must be maintained to avoid toxicity (Bene作者: habitat 時間: 2025-3-31 04:02 作者: chlorosis 時間: 2025-3-31 08:31 作者: 針葉 時間: 2025-3-31 09:57 作者: 哀悼 時間: 2025-3-31 14:02 作者: Project 時間: 2025-3-31 17:53
