標(biāo)題: Titlebook: Direct Mechanisms in Cholesterol Modulation of Protein Function; Avia Rosenhouse-Dantsker,Anna N. Bukiya Book 2019 The Editor(s) (if appli [打印本頁] 作者: CAP 時(shí)間: 2025-3-21 19:09
書目名稱Direct Mechanisms in Cholesterol Modulation of Protein Function影響因子(影響力)
書目名稱Direct Mechanisms in Cholesterol Modulation of Protein Function影響因子(影響力)學(xué)科排名
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書目名稱Direct Mechanisms in Cholesterol Modulation of Protein Function網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Direct Mechanisms in Cholesterol Modulation of Protein Function被引頻次
書目名稱Direct Mechanisms in Cholesterol Modulation of Protein Function被引頻次學(xué)科排名
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書目名稱Direct Mechanisms in Cholesterol Modulation of Protein Function讀者反饋
書目名稱Direct Mechanisms in Cholesterol Modulation of Protein Function讀者反饋學(xué)科排名
作者: Insubordinate 時(shí)間: 2025-3-21 21:58 作者: 親屬 時(shí)間: 2025-3-22 03:28 作者: bourgeois 時(shí)間: 2025-3-22 05:16
Kleingedrucktes ganz gro? geschriebened by NPC1 and NPC2, and briefly discuss recent findings of cholesterol binding and transport proteins beyond NPC1 and NPC2. We conclude with key questions and major challenges for future research on cholesterol transport by the NPC1 and NPC2 proteins.作者: Rheumatologist 時(shí)間: 2025-3-22 12:15
Crystallographic Studies of Steroid-Protein Interactionsays. Proteins found in some bacteria that bind and metabolize steroids have been investigated as well. A survey of the steroid-protein complexes that have been studied using crystallography and the insight learned from them is presented.作者: 甜瓜 時(shí)間: 2025-3-22 14:38
Effects of Cholesterol on GPCR Function: Insights from Computational and Experimental Studies complex system in order to shed more light on cholesterol molecular basis of action. The results of molecular simulations that complemented experimental data may reveal new aspects of GPCR-cholesterol interactions and may provide a comprehensive understanding of receptor function.作者: 甜瓜 時(shí)間: 2025-3-22 19:55
Insights into the Molecular Mechanisms of Cholesterol Binding to the NPC1 and NPC2 Proteinsed by NPC1 and NPC2, and briefly discuss recent findings of cholesterol binding and transport proteins beyond NPC1 and NPC2. We conclude with key questions and major challenges for future research on cholesterol transport by the NPC1 and NPC2 proteins.作者: travail 時(shí)間: 2025-3-22 23:47
0065-2598 erts in their fields and provide international perspective.R.In this book, renowned scientists describe how cholesterol interacts with various proteins. Recent progress made in the high-resolution visualization of cholesterol-protein interactions using crystallography and cryogenic electron microsco作者: 中國紀(jì)念碑 時(shí)間: 2025-3-23 03:39
Philipp Zimmer,Eva Zopf,Freerk Baumannng these effects have remained elusive. There appear to be multiple mechanisms by which cholesterol interacts with proteins. A complete understanding of cholesterol-sensing motifs is still undergoing refinement. Initially, cholesterol was thought to exert only non-specific effects on membrane fluidi作者: 不知疲倦 時(shí)間: 2025-3-23 09:33
Gesamtbetrachtung nach Haushaltsebenen,and intracellular signaling. X-ray crystallography has served as a successful tool for gaining understanding of the structural and mechanistic aspects of these functions by providing snapshots of steroids in complex with various types of proteins. These proteins include nuclear receptors activated b作者: OVER 時(shí)間: 2025-3-23 12:57
https://doi.org/10.1057/9780230600751erlying these interactions, a growing number of studies have focused on determining the crystal structures of a variety of proteins complexed with cholesterol. These include structures in which cholesterol binds to transmembrane domains, and structures in which cholesterol interacts with soluble one作者: AUGER 時(shí)間: 2025-3-23 17:18
She Got Game, but She Don’t Got Fameing roles in various biological processes. The first high-resolution crystal structure of a transmembrane protein in complex with cholesterol was a human β.-adrenergic receptor structure deposited to the Protein Data Bank in 2007. Since then, the number of the cholesterol-bound crystal structures ha作者: 殖民地 時(shí)間: 2025-3-23 18:05
She Got Game, but She Don’t Got Fametargets that is influenced by the membrane environment and external functions. These multifunctional factors make the understanding of the molecular mechanism of action in greater detail an entirely difficult task. Significant efforts have been made for better understanding the role of multi-directi作者: octogenarian 時(shí)間: 2025-3-24 00:43 作者: 失誤 時(shí)間: 2025-3-24 03:16 作者: 潛伏期 時(shí)間: 2025-3-24 08:09
Kleingedrucktes ganz gro? geschriebenerol. Our current understanding of this process developed with just over two decades of research. Since the cloning of the genes encoding the NPC1 and NPC2 proteins, studies of the biochemical defects observed when either gene is mutated along with computational and structural studies have unraveled作者: bronchodilator 時(shí)間: 2025-3-24 14:42
Direct Mechanisms in Cholesterol Modulation of Protein Function978-3-030-14265-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: organic-matrix 時(shí)間: 2025-3-24 17:59 作者: MERIT 時(shí)間: 2025-3-24 20:07 作者: Cubicle 時(shí)間: 2025-3-24 23:16
https://doi.org/10.1007/978-3-030-14265-0cholesterol modulation; protein function; cholesterol binding; steroid-protein interaction; lipid membra作者: coagulate 時(shí)間: 2025-3-25 05:02 作者: OVERT 時(shí)間: 2025-3-25 10:09
Cholesterol-Recognition Motifs in Membrane Proteinsng these effects have remained elusive. There appear to be multiple mechanisms by which cholesterol interacts with proteins. A complete understanding of cholesterol-sensing motifs is still undergoing refinement. Initially, cholesterol was thought to exert only non-specific effects on membrane fluidi作者: 合唱隊(duì) 時(shí)間: 2025-3-25 13:54
Crystallographic Studies of Steroid-Protein Interactionsand intracellular signaling. X-ray crystallography has served as a successful tool for gaining understanding of the structural and mechanistic aspects of these functions by providing snapshots of steroids in complex with various types of proteins. These proteins include nuclear receptors activated b作者: exigent 時(shí)間: 2025-3-25 19:29 作者: 小蟲 時(shí)間: 2025-3-25 20:20 作者: Yourself 時(shí)間: 2025-3-26 01:56 作者: 榮幸 時(shí)間: 2025-3-26 04:42
Cholesterol as a Key Molecule That Regulates TRPV1 Channel Function channels, are molecules inserted in cell membranes and their activity is regulated by cholesterol and other molecules of a lipidic nature present in them. The molecular mechanisms underlying the regulation of ion channels by lipids and similar molecules have been?an object of study for several year作者: 廣告 時(shí)間: 2025-3-26 09:19
Cholesterol Binding Sites in Inwardly Rectifying Potassium Channelsocytes and muscle cells, and setting the resting membrane potential, heart rate, vascular tone, insulin release, and salt flow across epithelia. These processes are regulated by a variegated list of modulators. In particular, in recent years, cholesterol has been shown to modulate a growing number o作者: RODE 時(shí)間: 2025-3-26 14:51
Insights into the Molecular Mechanisms of Cholesterol Binding to the NPC1 and NPC2 Proteinserol. Our current understanding of this process developed with just over two decades of research. Since the cloning of the genes encoding the NPC1 and NPC2 proteins, studies of the biochemical defects observed when either gene is mutated along with computational and structural studies have unraveled作者: Esophagus 時(shí)間: 2025-3-26 18:24
Book 2019art starts with a tour into common cholesterol recognition motifs, followed by an overview of the major classes of steroid-binding proteins. It then continues with two chapters that present a comprehensive analysis of molecular and structural characteristics of cholesterol binding sites in transmemb作者: 沙文主義 時(shí)間: 2025-3-26 22:35 作者: 死亡率 時(shí)間: 2025-3-27 02:14 作者: Apoptosis 時(shí)間: 2025-3-27 06:41 作者: brother 時(shí)間: 2025-3-27 10:42
Cholesterol as a Key Molecule That Regulates TRPV1 Channel Functionntrol pain. To date, several activators and positive modulators of the activity of TRPV1 have been described. However, very few naturally-occurring inhibitors are known. An endogenously-produced molecule that inhibits the activity of TRPV1 is cholesterol. This chapter focuses on describing the mecha作者: 大喘氣 時(shí)間: 2025-3-27 15:30 作者: abysmal 時(shí)間: 2025-3-27 17:45 作者: 記成螞蟻 時(shí)間: 2025-3-28 00:42
https://doi.org/10.1057/9780230600751ane domains. The interactions between cholesterol and the protein in both cases critically depends on hydrophobic and aromatic residues. In addition, cholesterol binding sites in both types of domains involve polar and/or charged residues. However, the percentage of appearance of the different types作者: 雕鏤 時(shí)間: 2025-3-28 03:14
She Got Game, but She Don’t Got Fameh allows us to systematically assess the flexibility and variability of cholesterols in transmembrane proteins. Together, this joint analysis reveals the common characteristics among the observed cholesterol structures, thereby offering important guidelines for prediction and modification of potenti作者: 嘲弄 時(shí)間: 2025-3-28 08:03 作者: 分發(fā) 時(shí)間: 2025-3-28 13:59
Kleingedrucktes ganz gro? geschriebensterol whereas Kir3.2^ and Kir3.4* were both up-regulated by cholesterol. Despite the opposite impact of cholesterol on these Kir3 channels compared to Kir2.1, putative cholesterol binding sites in all three channels were identified in equivalent transmembrane domains. Interestingly, however, there
