標(biāo)題: Titlebook: Dipeptidyl Aminopeptidases in Health and Disease; Nathan Back,Irun R. Cohen,Rodolfo Paoletti Book 2003 The Editor(s) (if applicable) and T [打印本頁] 作者: indulge 時(shí)間: 2025-3-21 17:37
書目名稱Dipeptidyl Aminopeptidases in Health and Disease影響因子(影響力)
書目名稱Dipeptidyl Aminopeptidases in Health and Disease影響因子(影響力)學(xué)科排名
書目名稱Dipeptidyl Aminopeptidases in Health and Disease網(wǎng)絡(luò)公開度
書目名稱Dipeptidyl Aminopeptidases in Health and Disease網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Dipeptidyl Aminopeptidases in Health and Disease被引頻次
書目名稱Dipeptidyl Aminopeptidases in Health and Disease被引頻次學(xué)科排名
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書目名稱Dipeptidyl Aminopeptidases in Health and Disease年度引用學(xué)科排名
書目名稱Dipeptidyl Aminopeptidases in Health and Disease讀者反饋
書目名稱Dipeptidyl Aminopeptidases in Health and Disease讀者反饋學(xué)科排名
作者: agitate 時(shí)間: 2025-3-21 22:35 作者: 古董 時(shí)間: 2025-3-22 03:49 作者: 影響帶來 時(shí)間: 2025-3-22 04:53 作者: GROUP 時(shí)間: 2025-3-22 10:33
Re-Uptake Mechanisms of Peptide Fragments after DPP IV-Mediated Proteolysis in the Peripheral Nervouot ganglia of the species guinea pig by employing immunohistochemistry. This finding provides new insights into the fate of peptide fragments, following DPP IV-mediated proteolysis. The results indicate, that the fragments may be re-utilized via uptake mechanisms in the peripheral nervous system of 作者: BUDGE 時(shí)間: 2025-3-22 14:51
Dipeptidyl Peptidase IV Gene Familyopeptidase activity with the closely related enzymes DPIV and FAP. The similarities between DP8, DP9 and DPIV in tissue expression pattern suggest a potential role for DP8 and DP9 in liver disease, T cell activation and immune function. The role of the two novel enzymes DP8 and DP9 and the other non作者: BUDGE 時(shí)間: 2025-3-22 19:23 作者: 浪費(fèi)物質(zhì) 時(shí)間: 2025-3-22 21:50 作者: 制定法律 時(shí)間: 2025-3-23 05:04
Investigation of DP IV-dependent Protein-Protein Interactions using Surface Plasmon Resonancesubstances which can interfere with such interactions with extracellular matrix proteins..Our data suggest the hypothesis that one ore more components localised at the membrane fraction are involved in DP IV mediated binding of cells on extracellular matrix.作者: 昏暗 時(shí)間: 2025-3-23 08:51 作者: 傳染 時(shí)間: 2025-3-23 13:03
CD26/DPP IV in Experimental and Clinical Organ Transplantationd with the enzymatic activity. .: In models of experimental cardiac allograft transplantation (HTx), we analyzed the role of CD26/DPP IV during organ rejection. Also, we investigated CD26 enzymatic and cellular expression in human recipients of kidney transplants (Tx). .: Heterotopic HTx in rats, mo作者: jungle 時(shí)間: 2025-3-23 15:36
Inhibition of Dipeptidylpeptidase IV (DPP IV, CD26) Activity Modulates Surface Expression of CTLA-4 hibitors of DPP IV activity may well explain the potent anti-abortogenic effect observed here and lead to novel therapeutic applications of DPP IV inhibitors in immune-related disorders and autoimmune diseases. Further studies are needed to elucidate the intracellular and molecular mechanisms underl作者: Instrumental 時(shí)間: 2025-3-23 19:52 作者: 挖掘 時(shí)間: 2025-3-23 22:31
Dipeptidyl Aminopeptidases in Health and Disease978-0-306-47920-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 侵害 時(shí)間: 2025-3-24 05:11
Symbols and How We Came to Be Humanardly surprising that many of them are indeed found truncated .. However, not all substrates are cleaved with the same efficiency. The molecular properties of DPPIV involved in substrate recognition are still poorly understood.作者: 量被毀壞 時(shí)間: 2025-3-24 10:20
Specification of Software Systemssubstances which can interfere with such interactions with extracellular matrix proteins..Our data suggest the hypothesis that one ore more components localised at the membrane fraction are involved in DP IV mediated binding of cells on extracellular matrix.作者: 聽寫 時(shí)間: 2025-3-24 11:10
https://doi.org/10.1007/978-0-85729-277-3hibitors of DPP IV activity may well explain the potent anti-abortogenic effect observed here and lead to novel therapeutic applications of DPP IV inhibitors in immune-related disorders and autoimmune diseases. Further studies are needed to elucidate the intracellular and molecular mechanisms underlying this effect.作者: 脫毛 時(shí)間: 2025-3-24 18:31 作者: Stagger 時(shí)間: 2025-3-24 20:05 作者: 口音在加重 時(shí)間: 2025-3-24 23:54
Inhibition of Dipeptidylpeptidase IV (DPP IV, CD26) Activity Modulates Surface Expression of CTLA-4 hibitors of DPP IV activity may well explain the potent anti-abortogenic effect observed here and lead to novel therapeutic applications of DPP IV inhibitors in immune-related disorders and autoimmune diseases. Further studies are needed to elucidate the intracellular and molecular mechanisms underlying this effect.作者: 過于平凡 時(shí)間: 2025-3-25 07:02
Kevin Machino,Marshall Haden,Ankur VermaXaa-Pro dipeptides and amino acid pyrrolidides as well as thiazolidides are well-known competitive inhibitors of DPP IV. If these compounds contain the amino acid Trp the compounds are in many cases linear mixed-type or hyperbolic mixed-type inhibitors.作者: resistant 時(shí)間: 2025-3-25 08:01
Different Inhibition Mechanisms of Dipeptidyl Peptidase IV by Tryptophan Containing Peptides and AmiXaa-Pro dipeptides and amino acid pyrrolidides as well as thiazolidides are well-known competitive inhibitors of DPP IV. If these compounds contain the amino acid Trp the compounds are in many cases linear mixed-type or hyperbolic mixed-type inhibitors.作者: allergy 時(shí)間: 2025-3-25 15:17 作者: Malcontent 時(shí)間: 2025-3-25 18:03 作者: flaggy 時(shí)間: 2025-3-25 23:27 作者: 注意到 時(shí)間: 2025-3-26 02:30
Specific Sports-Related InjuriesP IV does not affect immediate chemotactic effects. Since I-TAC is a relatively good chemokine substrate, this conclusion should be valid also for other chemokines. Furthermore, many chemokines are redundant, and not all of them are substrates for DPP IV..Therefore, from the pharmacological view we 作者: irreparable 時(shí)間: 2025-3-26 06:09
Specific Sports-Related Injuriesot only on the primary structure around the catalytic site rather C-terminal located secondary interactions strongly influence the binding and catalysis of the substrates. Such interaction sites seem to force the ligand in a proper orientation to the active site of DP IV. As result of these relation作者: 祖?zhèn)髫?cái)產(chǎn) 時(shí)間: 2025-3-26 11:05 作者: Liberate 時(shí)間: 2025-3-26 15:47 作者: accrete 時(shí)間: 2025-3-26 18:04
https://doi.org/10.1007/978-1-4613-0091-5opeptidase activity with the closely related enzymes DPIV and FAP. The similarities between DP8, DP9 and DPIV in tissue expression pattern suggest a potential role for DP8 and DP9 in liver disease, T cell activation and immune function. The role of the two novel enzymes DP8 and DP9 and the other non作者: Traumatic-Grief 時(shí)間: 2025-3-26 23:01
https://doi.org/10.1007/978-3-642-14538-4epresents an alternate approach to previous published methods were DP IV was expressed in cell culture (Tanaka .) with lower production rates and to the production in insect cells (Dobers .) Biochemical and kinetic characterization demonstrated that the soluble recombinant DP IV displayed similar pr作者: 客觀 時(shí)間: 2025-3-27 03:18 作者: Astigmatism 時(shí)間: 2025-3-27 08:08
Specification of Software Systemssubstances which can interfere with such interactions with extracellular matrix proteins..Our data suggest the hypothesis that one ore more components localised at the membrane fraction are involved in DP IV mediated binding of cells on extracellular matrix.作者: 沐浴 時(shí)間: 2025-3-27 11:49
Specification of Software Systemsand in vivo. The most prominent changes observed include the activation of cellular signal transduction pathways such as MAP kinases Erk1/2 or the Wnt-pathway, a decrease of production and release of “pro-inflammatory” cytokines (IL-2, IL-12) and, most importantly, an induction of expression and rel作者: Delectable 時(shí)間: 2025-3-27 16:02
https://doi.org/10.1007/978-0-85729-277-3d with the enzymatic activity. .: In models of experimental cardiac allograft transplantation (HTx), we analyzed the role of CD26/DPP IV during organ rejection. Also, we investigated CD26 enzymatic and cellular expression in human recipients of kidney transplants (Tx). .: Heterotopic HTx in rats, mo作者: 暫時(shí)過來 時(shí)間: 2025-3-27 20:48 作者: 壕溝 時(shí)間: 2025-3-27 22:16 作者: Reverie 時(shí)間: 2025-3-28 03:17 作者: 撫慰 時(shí)間: 2025-3-28 08:24
The Specificity of DP IV for Natural Substrates is Peptide Structure Determineds the hydrolysis of peptides with non-proline and non-alanine residues in P.-position (Ser, Val, Gly) becomes possible in longer peptides..Such specific secondary interactions opens the opportunity for development of new inhibitors.作者: QUAIL 時(shí)間: 2025-3-28 14:20
Characterisation of Human DP IV Produced by a , Expression Systemoperties as DP IV purified from porcine kidney regarding size, activity, isoelectric point and glycosylation. Furthermore, the new expression method enables future structure-function related studies of DP IV.作者: obscurity 時(shí)間: 2025-3-28 16:43
0065-2598 nopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in im作者: 侵略者 時(shí)間: 2025-3-28 22:50 作者: 小爭(zhēng)吵 時(shí)間: 2025-3-29 02:29 作者: Asseverate 時(shí)間: 2025-3-29 04:10
Dipeptidyl Peptidase IV Gene Familyotential role for DP8 and DP9 in liver disease, T cell activation and immune function. The role of the two novel enzymes DP8 and DP9 and the other non-enzyme member DPL2 in human disease will be the focus of further studies.作者: 變白 時(shí)間: 2025-3-29 10:07
Isolation and Characterization of Attractin-2 insertion of the isoforms 1, 2, 4 and 5 and questioned the predicted Ser 26 as an active site residue..We could not find differences between DP IV and attractin with respect to the specificity of inhibitors or substrates. Attractin is also capable to release dipeptides from higher molecular substrates such as neuropeptide Y.作者: follicular-unit 時(shí)間: 2025-3-29 13:26
Specific Sports-Related Injuriesthink that DPP IV inhibitors have only little or no side effects on chemokines. Such side effects would be the prolongation or increase of inflammatory responses which have, to our knowledge, not yet been reported after in vivo applications in humans.作者: 頌揚(yáng)本人 時(shí)間: 2025-3-29 19:12 作者: Nonthreatening 時(shí)間: 2025-3-29 20:08 作者: 敏捷 時(shí)間: 2025-3-30 00:35
Structure-Function Relationship of DPP IV: Insights into its Dimerisation and Gelatinase Activity作者: RODE 時(shí)間: 2025-3-30 06:00
Exploration of the Active Site of Dipeptidyl Peptidase IV From 作者: 上下連貫 時(shí)間: 2025-3-30 10:15 作者: 白楊 時(shí)間: 2025-3-30 15:53
Seprase-DPPIV Association and Prolyl Peptidase and Gelatinase Activities of the Protease Complex作者: 憤怒事實(shí) 時(shí)間: 2025-3-30 19:32
Dipeptidyl Peptidase-IV Activity and/or Structure Homologues (DASH) in Transformed Neuroectodermal C作者: maudtin 時(shí)間: 2025-3-31 00:13 作者: 污點(diǎn) 時(shí)間: 2025-3-31 03:03
0065-2598 ne mechanisms and immune disorders, .- Cancer and angiogenesis, .- Diabetes and metabolism, .- Therapeutic implications. .978-1-4757-8730-6978-0-306-47920-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: CBC471 時(shí)間: 2025-3-31 06:56
New Results on the Conformations of Potent DP IV (CD26) Inhibitors bearing the N-terminal , Structur structural class for the interaction with DP IV..Thus, the considerable enhancement of the inhibition capacity of both .-. and . compared to the moderate inhibitor ., .=2.68±0.01 10. ., can only be due to tryptophan in the second position suggesting that its side chain is favored to exhibit attract作者: Minatory 時(shí)間: 2025-3-31 10:16 作者: NOVA 時(shí)間: 2025-3-31 17:18
Synergistic Action of DPIV and APN in the Regulation of T Cell FunctionPN or DPIV alone. Therefore, the simultaneous inhibition of these enzymes represents a promising strategy for the pharmacological therapy of T cell mediated diseases such as autoimmune disease, inflammation, allergy, and allograft rejection.作者: 四指套 時(shí)間: 2025-3-31 18:05
CD26/DPP IV in Experimental and Clinical Organ Transplantationific inhibition abrogated acute (p<0.0001) and accelerated (p<0.01) rejection, impairing cytotoxicity and allospecific Ig-synthesis. Kidney recipients displayed a significant drop in CD26 expression on PBL for up to 18 months postoperatively (p<0.001). CD4, 8, 45, 122 and ADA expression kinetics wer作者: canonical 時(shí)間: 2025-3-31 22:06
Book 2003The sections of the book focus on various topics: ..- Structure and function of dipeptidyl aminopeptidases, .- DPP IV-like proteins, .- Immune mechanisms and immune disorders, .- Cancer and angiogenesis, .- Diabetes and metabolism, .- Therapeutic implications. .
