標(biāo)題: Titlebook: Diagnostic and Therapeutic Antibodies; Andrew J. T. George,Catherine E. Urch Book 2000 Humana Press 2000 [打印本頁(yè)] 作者: Destruct 時(shí)間: 2025-3-21 17:37
書(shū)目名稱Diagnostic and Therapeutic Antibodies影響因子(影響力)
書(shū)目名稱Diagnostic and Therapeutic Antibodies影響因子(影響力)學(xué)科排名
書(shū)目名稱Diagnostic and Therapeutic Antibodies網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Diagnostic and Therapeutic Antibodies網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Diagnostic and Therapeutic Antibodies被引頻次
書(shū)目名稱Diagnostic and Therapeutic Antibodies被引頻次學(xué)科排名
書(shū)目名稱Diagnostic and Therapeutic Antibodies年度引用
書(shū)目名稱Diagnostic and Therapeutic Antibodies年度引用學(xué)科排名
書(shū)目名稱Diagnostic and Therapeutic Antibodies讀者反饋
書(shū)目名稱Diagnostic and Therapeutic Antibodies讀者反饋學(xué)科排名
作者: 小教堂 時(shí)間: 2025-3-21 20:17
Polyclonal and Monoclonal Antibodies unlimited supply of a single antibody that is clearly defined and of reproducible specificity and affinity is of greater value. To produce such a reagent it is necessary to isolate and culture a single clone of B lymphocytes secreting antibody of the appropriate characteristics-that is, to produce 作者: G-spot 時(shí)間: 2025-3-22 00:46 作者: 債務(wù) 時(shí)間: 2025-3-22 05:44 作者: FEAT 時(shí)間: 2025-3-22 09:42
Antibody-Based Therapies in Infectious Diseasesccesses with immune serum were observed in treatment and prevention of other infectious diseases, which include . meningitis, measles, diphtheria, hepatitis A and B, poliovirus infection, and cytomegalovirus (CMV) infection (.). However, numerous problems have been observed with immune sera, includi作者: 語(yǔ)源學(xué) 時(shí)間: 2025-3-22 13:17
Antibodies for Immunoassayshormones, peptides, e.g., vasopressin, proteins, e.g., cytokines, as well as carbohydrate structures, e.g., CA-125. Immunoassay technology has developed to such an extent that it is probably the most versatile analytical tool available able to identify and quantify epitopic structures across the mil作者: 語(yǔ)源學(xué) 時(shí)間: 2025-3-22 20:01 作者: DEMN 時(shí)間: 2025-3-23 01:03 作者: overweight 時(shí)間: 2025-3-23 05:28 作者: ENNUI 時(shí)間: 2025-3-23 06:35
B. Müller,A. Marek,H.-Th. Jankapersonal communication) have recently achieved more than 70% complete responses in posttransplant lymphoma treated with a chimeric anti-CD20 mAb, and Maloney and co-workers (.) recently reported a 50% response rate in relapsed, low-grade, NHL, with a 10---11 mo duration. Encouragingly, patients in t作者: 先行 時(shí)間: 2025-3-23 11:38 作者: Ornithologist 時(shí)間: 2025-3-23 14:15 作者: Breach 時(shí)間: 2025-3-23 18:52 作者: Aboveboard 時(shí)間: 2025-3-24 00:06 作者: 沙草紙 時(shí)間: 2025-3-24 05:38
Frank C. Maier,Maofeng Dou,Maria Fytaus ways. The difficulty we have now is different. There are just too many potential new antibody-based treatments for them all to be properly evaluated in the clinic. Many will still fail because of factors that are hard to predict from experiments: unexpected toxicity, biological heterogeneity of t作者: RACE 時(shí)間: 2025-3-24 08:19
Book 2000y engineering has rejuvenated the field, allowing both the modification of antibodies to improve their in vivo pr- erties and the isolation of novel antibody molecules by such techniques as phage display. The results of recent clinical trials have demonstrated unequivocally the benefit of antibody t作者: 不出名 時(shí)間: 2025-3-24 14:43
Antibodies for Transplantatione the host’s T cells, the lymphocytes responsible for recognizing and attacking foreign proteins, cells, and tissues. Antibodies can also be used to eliminate any highly immunogenic passenger cells from a donor graft prior to transplantation, and antibodies can mask or conceal antigens present on donor cells that might trigger rejection.作者: enormous 時(shí)間: 2025-3-24 15:48 作者: Grievance 時(shí)間: 2025-3-24 19:23
Purification of Monoclonal Antibodies Using Protein A/Gs, enabling them to investigate previously unknown molecules. More recently mAbs have also gained an important role in medicine, e.g., in helping to prevent allograft rejection and in the treatment of digoxin poisoning.作者: 大方一點(diǎn) 時(shí)間: 2025-3-25 02:57 作者: MAOIS 時(shí)間: 2025-3-25 04:02 作者: 偶像 時(shí)間: 2025-3-25 11:02 作者: 爭(zhēng)論 時(shí)間: 2025-3-25 12:42
The Antibody Moleculeing regarding the nature of the antibody molecule. Indeed, the earliest theories suggested that the antitoxins were derived by modification of the toxinintriguingly similar “antigen incorporation” theories were propounded as late as 1930 (.).作者: boisterous 時(shí)間: 2025-3-25 17:32
Production of Monoclonal Antibodies-sitology, physiology, genetics, and molecular biology; and also in areas of clinical medicine, such as pathology, hematology, oncology, and infectious disease. The contribution of mAbs to science and clinical medicine was recognized in 1984 by the award of the Nobel Prize for Medicine to K?hler and Milstein.作者: enormous 時(shí)間: 2025-3-25 20:30
Book 2000n the context of cancer. Antibodies appeared to offer the “magic bullet” that would allow the specific destruction of neoplastic cells. H- ever, many years’ effort resulted in very few cases of successful immu- therapy with antibodies. As a result there was a major backlash against antibody therapy,作者: right-atrium 時(shí)間: 2025-3-26 01:18 作者: pessimism 時(shí)間: 2025-3-26 08:04 作者: 難理解 時(shí)間: 2025-3-26 11:41
Massive and Massless Four-Loop Integralss site, size, vasculature, and antigen density on the tumor cell surface. Animal models for studying these parameters are usually based on mice or rats bearing transplanted tumors. In this chapter, various tumor model systems will be described with some discussion of what data can be obtained using them.作者: 共同確定為確 時(shí)間: 2025-3-26 15:30 作者: Terminal 時(shí)間: 2025-3-26 19:22 作者: exclamation 時(shí)間: 2025-3-26 23:55
The Antibody Moleculedies against the bacterial exotoxins (.). Around the same time, it was shown that antisera against cholera vibrios could transfer immunity to na?ve animals, and also kill the bacteria in vitro (.). However, although antitoxin antibodies rapidly found clinical application, there was little understand作者: 施魔法 時(shí)間: 2025-3-27 03:51
Polyclonal and Monoclonal Antibodiesttractiveness of antibodies as laboratory and clinical reagents. One aspect of the body’s reaction to invasion by a microorganism is the activation and clonal expansion of antigen-reactive B lymphocytes. Once these have matured into plasma cells, each clone of cells will secrete its own unique speci作者: Spinous-Process 時(shí)間: 2025-3-27 06:42
Phage Display Technology, the method has limitations. The use of recombinant DNA technology and demonstration by Smith 1985 (.) that peptides can be expressed on the surface of filamentous bacteriophages have permitted the development of a powerful new methodology for the generation and isolation of novel antibody-based re作者: Protein 時(shí)間: 2025-3-27 10:50
Antibodies for Neoplastic Diseaseity and affinity. These reagents therefore have long held promise as a means of influencing the growth and spread of malignant disease. Over a number of decades therapeutic antibodies have been developed either as single entities or conjugated to a variety of potential disease-ameliorating agents.作者: Asparagus 時(shí)間: 2025-3-27 13:37
The Application of Monoclonal Antibodies in the Treatment of Lymphomacan be made with precise specificity and in almost unlimited amounts. In addition, mAbs can be selected or engineered to efficiently recruit the body’s effector systems, such as complement and natural killer cells, against the unwanted cells in much the same way as they might destroy an invading pat作者: 匍匐前進(jìn) 時(shí)間: 2025-3-27 19:54 作者: 施魔法 時(shí)間: 2025-3-28 01:04 作者: 不合 時(shí)間: 2025-3-28 05:34 作者: 種子 時(shí)間: 2025-3-28 09:50
Antibody-Based Therapies in Infectious Diseasesinning of the 20th century, serum therapy had taken a place in standard treatment protocols for several infectious diseases, such as meningitis, diphtheria, tetanus, and lobar pneumonia. As early as 1906, antimeningococcal serum was intravenously used as a treatment for meningitis, since it was prov作者: gospel 時(shí)間: 2025-3-28 11:55 作者: invert 時(shí)間: 2025-3-28 18:34
Antibodies for ImmunoassaysAn immunoassay is an analytical technique, quantitative or qualitative, that relies absolutely on the specificity and affinity of the interaction between epitope and paratope for generation of a detectable response. The actual detection of this binding interaction can be via one of literally hundred作者: 想象 時(shí)間: 2025-3-28 21:46
Intellectual Propertyexpression of ideas, and the inventors of such ideas (.). Intellectual property has many of the characteristics of real property (houses, buildings, and so forth); intellectual property can be bought, sold, assigned, and licensed. Additionally, the owner of IP can prevent “trespass” on his property 作者: 終止 時(shí)間: 2025-3-29 01:47
From Laboratory to Clinic, passive antibody therapy was developed as an effective treatment for infectious diseases and for neutralization of toxins, and continues to be used to this day. Meanwhile, there have been continued efforts to use antibodies for cancer therapy, starting with the pioneering work of Hericourt and Ric作者: Confidential 時(shí)間: 2025-3-29 04:35 作者: Pseudoephedrine 時(shí)間: 2025-3-29 10:20
Purification of Monoclonal Antibodies Using Protein A/Ghe fusion of B cells (secreting the relevant mAb) with a nonsecreting myeloma cell line (.). Since then mAbs have become a central tool for researchers, enabling them to investigate previously unknown molecules. More recently mAbs have also gained an important role in medicine, e.g., in helping to p作者: 初次登臺(tái) 時(shí)間: 2025-3-29 11:31
Preparation of Monoclonal Antibodies Using Ion Exchange Chromatography reaction of immunoglobulins with immobilized ligands, as is the case of adsorption chromatography, which uses either protein A or G, but on the charge of the biomolecules. Some immunoglobulins bind only weakly or not at all to protein A or G, and for these molecules ion exchange is the method of ch作者: Anterior 時(shí)間: 2025-3-29 17:42 作者: 獨(dú)行者 時(shí)間: 2025-3-29 20:33
Antibodies for Inflammatory Diseaseentification of potential target molecules and the immunotherapeutic mechanisms to be recruited by antibodies targeting these molecules. Regardless of the target antigen, antibodies may modify immune responses by:作者: acheon 時(shí)間: 2025-3-30 02:33
Diagnostic and Therapeutic Antibodies978-1-59259-076-6Series ISSN 1543-1894 Series E-ISSN 1940-6037 作者: PALMY 時(shí)間: 2025-3-30 05:27
Conductance of Correlated Nanostructuresity and affinity. These reagents therefore have long held promise as a means of influencing the growth and spread of malignant disease. Over a number of decades therapeutic antibodies have been developed either as single entities or conjugated to a variety of potential disease-ameliorating agents.作者: GEAR 時(shí)間: 2025-3-30 11:44 作者: 欲望小妹 時(shí)間: 2025-3-30 15:39
Andrew J. T. George,Catherine E. UrchIncludes supplementary material: 作者: THE 時(shí)間: 2025-3-30 18:09 作者: 考博 時(shí)間: 2025-3-30 23:20
Supersolid Fermions Inside Harmonic Trapsdies against the bacterial exotoxins (.). Around the same time, it was shown that antisera against cholera vibrios could transfer immunity to na?ve animals, and also kill the bacteria in vitro (.). However, although antitoxin antibodies rapidly found clinical application, there was little understand作者: 影響帶來(lái) 時(shí)間: 2025-3-31 01:19
Supersolid Fermions Inside Harmonic Trapsttractiveness of antibodies as laboratory and clinical reagents. One aspect of the body’s reaction to invasion by a microorganism is the activation and clonal expansion of antigen-reactive B lymphocytes. Once these have matured into plasma cells, each clone of cells will secrete its own unique speci作者: perimenopause 時(shí)間: 2025-3-31 06:01 作者: hemophilia 時(shí)間: 2025-3-31 11:18 作者: 歪曲道理 時(shí)間: 2025-3-31 15:10
B. Müller,A. Marek,H.-Th. Jankacan be made with precise specificity and in almost unlimited amounts. In addition, mAbs can be selected or engineered to efficiently recruit the body’s effector systems, such as complement and natural killer cells, against the unwanted cells in much the same way as they might destroy an invading pat作者: Lice692 時(shí)間: 2025-3-31 21:36 作者: Cougar 時(shí)間: 2025-3-31 22:33
Ping Wang,Jochen Fr?hlich,Ulrich Maasmmune and inflammatory responses. By binding their cognate receptors on target cells, these short-lived molecules play a role in many important biological processes, including cell proliferation, activation, death, and differentiation. During an inflammatory response many cytokines are synthesized b作者: FOVEA 時(shí)間: 2025-4-1 02:32
