標(biāo)題: Titlebook: Diabetic Nephropathy; Methods and Protocol Luigi Gnudi,David A. Long Book 2020 Springer Science+Business Media, LLC, part of Springer Natur [打印本頁] 作者: Autonomous 時間: 2025-3-21 17:45
書目名稱Diabetic Nephropathy影響因子(影響力)
書目名稱Diabetic Nephropathy影響因子(影響力)學(xué)科排名
書目名稱Diabetic Nephropathy網(wǎng)絡(luò)公開度
書目名稱Diabetic Nephropathy網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Diabetic Nephropathy被引頻次
書目名稱Diabetic Nephropathy被引頻次學(xué)科排名
書目名稱Diabetic Nephropathy年度引用
書目名稱Diabetic Nephropathy年度引用學(xué)科排名
書目名稱Diabetic Nephropathy讀者反饋
書目名稱Diabetic Nephropathy讀者反饋學(xué)科排名
作者: 吹氣 時間: 2025-3-21 21:51
Book 2020oiding known pitfalls.?.Authoritative and practical, .Diabetic Nephropathy: Methods and Protocols. seeks to foster new research directions and inspire ideas to enhance our understanding of diabetic nephropathy and todevelop treatments for this condition..作者: Rankle 時間: 2025-3-22 03:19 作者: 無所不知 時間: 2025-3-22 06:18
Maike R?nnau-B?se,Klaus Fr?hlich-Gildhoffx of large-pore pathways and use of labeled albumin provides direct relevance to the clinically important parameter of albuminuria. The combination of the two approaches provides a fantastic tool to elucidate endothelial barrier function in vitro including in response to cytokines, pathological stim作者: Kaleidoscope 時間: 2025-3-22 11:49 作者: OATH 時間: 2025-3-22 15:45
https://doi.org/10.1007/978-3-658-16253-5tional force-displacement in separating renal tubular epithelial cells. Parameters such as unbinding forces, detachment energy, and distance to complete separation can be obtained from force-displacement (.) curves and are critical in assessing how physical changes of cellular adhesion contribute to作者: OATH 時間: 2025-3-22 17:55 作者: ALLEY 時間: 2025-3-22 21:51
Glomerular Endothelial Cells: Assessment of Barrier Properties In Vitrox of large-pore pathways and use of labeled albumin provides direct relevance to the clinically important parameter of albuminuria. The combination of the two approaches provides a fantastic tool to elucidate endothelial barrier function in vitro including in response to cytokines, pathological stim作者: 內(nèi)向者 時間: 2025-3-23 03:49 作者: 信任 時間: 2025-3-23 08:47 作者: genesis 時間: 2025-3-23 12:58
Sample Preparation and Stereological Methods for the Study of Glomerular Ultrastructure Using ElectrIn this chapter we describe conventional methods used for preparing renal tissue for transmission electron microscopy. We also describe a relatively new technique, serial block face scanning electron microscopy. Protocols are given for processing, sectioning, and imaging of tissue along with methods for obtaining quantitative data from the results.作者: 種族被根除 時間: 2025-3-23 17:42 作者: PHONE 時間: 2025-3-23 19:02 作者: excursion 時間: 2025-3-23 23:24
Isolating and Culturing Mouse Podocyte Cells to Study Diabetic Nephropathyhapter describes a method of isolating and culturing podocyte cells from mouse adult kidneys. In this way, podocytes with genetic modifications can be obtained from transgenic animals and they can be used to study the effects of the diabetic environment in vitro.作者: BILE 時間: 2025-3-24 04:52 作者: depreciate 時間: 2025-3-24 10:20
Legitimation durch Kommunikation?es known as slit diaphragms that contribute to the glomerular filtration barrier. The disruption of podocyte biology or slit diaphragm formation in humans is a precursor to albuminuria, renal failure, and cardiovascular morbidity. Due to genetic and functional similarities, the nephrocytes of . are 作者: 談判 時間: 2025-3-24 14:46 作者: Coma704 時間: 2025-3-24 15:55
Regierungssysteme und Demokratietypen progressive disease or test novel therapeutics. In this chapter we describe in detail the experimental procedures required to conduct the . rodent model, in which hyperglycemia and renin-dependent hypertension synergize to promote moderate proteinuria, renal fibrosis, and induction of many of the t作者: 羅盤 時間: 2025-3-24 22:08
Regierungssysteme und Demokratietypenhapter describes a method of isolating and culturing podocyte cells from mouse adult kidneys. In this way, podocytes with genetic modifications can be obtained from transgenic animals and they can be used to study the effects of the diabetic environment in vitro.作者: 耕種 時間: 2025-3-25 01:41
https://doi.org/10.1007/978-3-663-01446-1ease. Glomerular lesions constitute the most striking and consistent features identified in biopsies from patients with DKD, although tubulointerstitial injury has an important and often under-recognized role in the progression to overt nephropathy. In advanced stages of the disease, podocyte detach作者: 的’ 時間: 2025-3-25 06:48
Detlef Pollack,Volkhard Krech,Markus Heromergence of numerous tissue clearing strategies, and advancements in confocal and two-photon microscopy, enabling the study of intact organs and systems down to cellular and sub-cellular resolution. In this chapter, we describe a wholemount immunofluorescence technique for labeling structures in ren作者: 鋼盔 時間: 2025-3-25 08:31 作者: 朦朧 時間: 2025-3-25 15:20 作者: 健談的人 時間: 2025-3-25 18:19
Maike R?nnau-B?se,Klaus Fr?hlich-Gildhoffn in general and also to specific capillary beds including the renal glomerular capillaries. Endothelial dysfunction, including increased permeability, is a key component of diabetes-induced organ damage. Endothelial cells together with their glycocalyx, grown on porous membranes, provide an excelle作者: 行為 時間: 2025-3-25 21:25
https://doi.org/10.1007/978-3-531-92775-6lumen. The latter is sensed by intrinsic ER transmembrane proteins: IRE1α (inositol-requiring protein-1α), PERK (protein kinase RNA (PKR)-like ER kinase), and ATF6 (activating transcription factor 6) which when activated trigger the unfolded protein response (UPR), which includes an inhibition of pr作者: 征稅 時間: 2025-3-26 01:48
https://doi.org/10.1007/978-3-658-16253-5eflect the physiological state of their cells of origin. Recently, urinary extracellular vesicles have emerged as a valuable source of biomarkers for kidney and systemic disease..Unfortunately, all existing methods for extracellular vesicle isolation from urine are time consuming and/or expensive. T作者: EXCEL 時間: 2025-3-26 04:21 作者: 執(zhí)拗 時間: 2025-3-26 08:29 作者: 吼叫 時間: 2025-3-26 13:11 作者: 蹣跚 時間: 2025-3-26 17:56 作者: Fulminate 時間: 2025-3-26 21:53 作者: 起波瀾 時間: 2025-3-27 02:57
Diabetic Nephropathy: An Overview. The classical presentation of DN is characterized by hyperfiltration and albuminuria in the early phases which is then followed by a progressive renal function decline. The presentation of diabetic kidney disease (DKD) can vary especially in patients with T2DM where concomitant presence of other g作者: Wallow 時間: 2025-3-27 09:21
Modeling Podocyte Biology Using , Nephrocyteses known as slit diaphragms that contribute to the glomerular filtration barrier. The disruption of podocyte biology or slit diaphragm formation in humans is a precursor to albuminuria, renal failure, and cardiovascular morbidity. Due to genetic and functional similarities, the nephrocytes of . are 作者: 旋轉(zhuǎn)一周 時間: 2025-3-27 12:40
A Technique for Studying Glomerular Filtration Integrity in the Zebrafish Pronephrosdevelop translatable in vivo models to study genetic changes. This allows for functional validation of pathogenic mutations and establishes a system to understand the etiology of disease. Due to the ease of genetic manipulation and rapid . development, the zebrafish has become a valuable resource to作者: milligram 時間: 2025-3-27 14:35
Modeling Human Diabetic Kidney Disease by Combining Hyperglycemia and Hypertension in a Transgenic R progressive disease or test novel therapeutics. In this chapter we describe in detail the experimental procedures required to conduct the . rodent model, in which hyperglycemia and renin-dependent hypertension synergize to promote moderate proteinuria, renal fibrosis, and induction of many of the t作者: 火光在搖曳 時間: 2025-3-27 19:21 作者: 緯線 時間: 2025-3-28 01:32 作者: 耕種 時間: 2025-3-28 02:54
Tissue Clearing and Deep Imaging of the Kidney Using Confocal and Two-Photon Microscopymergence of numerous tissue clearing strategies, and advancements in confocal and two-photon microscopy, enabling the study of intact organs and systems down to cellular and sub-cellular resolution. In this chapter, we describe a wholemount immunofluorescence technique for labeling structures in ren作者: 小溪 時間: 2025-3-28 08:18 作者: 脖子 時間: 2025-3-28 10:38 作者: Colonoscopy 時間: 2025-3-28 17:47 作者: 忘川河 時間: 2025-3-28 20:45 作者: 甜得發(fā)膩 時間: 2025-3-29 02:40
Isolating Urinary Extracellular Vesicles as Biomarkers for Diabetic Diseaseeflect the physiological state of their cells of origin. Recently, urinary extracellular vesicles have emerged as a valuable source of biomarkers for kidney and systemic disease..Unfortunately, all existing methods for extracellular vesicle isolation from urine are time consuming and/or expensive. T作者: GLUT 時間: 2025-3-29 04:29 作者: 佛刊 時間: 2025-3-29 07:31
Detlef Pollack,Volkhard Krech,Markus Heroructural information than traditional sectioning and staining alone. Given the addition of paraffin embedding to our method, this hybrid protocol offers a powerful approach to combine confocal or two-photon findings with histological and further immunofluorescent analysis within the same tissue.作者: giggle 時間: 2025-3-29 14:26
Soziologische Religionstheorie nach dem ,uorescent agent that can be used as a renal marker as it is filtrated and completely excreted through the kidneys into the urine without reabsorption or secretion and without accumulation in the skin. The data recorded in the device are then analyzed with “GFRmeasure,” an open-source, freely downloadable, and user-friendly software.作者: nepotism 時間: 2025-3-29 18:15
Maike R?nnau-B?se,Klaus Fr?hlich-Gildhoffe, we detail an in vitro method to analyze glucose uptake in conditionally immortalized human podocytes (Saleem, J Am Soc Nephrol 13:630–638, 2002; Coward, Diabetes 54:3095–3102, 2005); this assay is useful for detecting changes in podocyte metabolism, nutrient sensing, and insulin sensitivity.作者: 仇恨 時間: 2025-3-29 22:02
https://doi.org/10.1007/978-3-658-16253-5s devised a set of new, quick, simple, and inexpensive techniques, based on hydrostatic filtration dialysis (HFD) of urine extremely suitable for diagnostic purposes. This novel approach represents a great potential for new diagnostics and understanding disease biology in general and brings the biomarker detection to the scope of all laboratories.作者: 值得贊賞 時間: 2025-3-30 03:38 作者: 貨物 時間: 2025-3-30 04:07 作者: 愛國者 時間: 2025-3-30 10:36
An In Vitro Method to Analyze Glucose Uptake in Podocytese, we detail an in vitro method to analyze glucose uptake in conditionally immortalized human podocytes (Saleem, J Am Soc Nephrol 13:630–638, 2002; Coward, Diabetes 54:3095–3102, 2005); this assay is useful for detecting changes in podocyte metabolism, nutrient sensing, and insulin sensitivity.作者: 多產(chǎn)魚 時間: 2025-3-30 12:29
Isolating Urinary Extracellular Vesicles as Biomarkers for Diabetic Diseases devised a set of new, quick, simple, and inexpensive techniques, based on hydrostatic filtration dialysis (HFD) of urine extremely suitable for diagnostic purposes. This novel approach represents a great potential for new diagnostics and understanding disease biology in general and brings the biomarker detection to the scope of all laboratories.作者: 使人入神 時間: 2025-3-30 18:22
1064-3745 expertsThis book provides a toolkit of novel research approaches for investigators to study diabetic nephropathy, including critical experimental models from the fly to the fish, cells in culture, and in vivo mammalian approaches. The collection also explores powerful techniques to image the kidney作者: gentle 時間: 2025-3-30 23:04
Regierungssysteme und Demokratietypendel, in which hyperglycemia and renin-dependent hypertension synergize to promote moderate proteinuria, renal fibrosis, and induction of many of the transcriptomic changes observed in the kidney of patients with progressive DN.
