標(biāo)題: Titlebook: Diabetes Mellitus; A risk factor for Al Yusaku Nakabeppu,Toshiharu Ninomiya Book 2019 Springer Nature Singapore Pte Ltd. 2019 Brain-derived [打印本頁(yè)] 作者: Opiate 時(shí)間: 2025-3-21 16:03
書目名稱Diabetes Mellitus影響因子(影響力)
書目名稱Diabetes Mellitus影響因子(影響力)學(xué)科排名
書目名稱Diabetes Mellitus網(wǎng)絡(luò)公開度
書目名稱Diabetes Mellitus網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Diabetes Mellitus被引頻次
書目名稱Diabetes Mellitus被引頻次學(xué)科排名
書目名稱Diabetes Mellitus年度引用
書目名稱Diabetes Mellitus年度引用學(xué)科排名
書目名稱Diabetes Mellitus讀者反饋
書目名稱Diabetes Mellitus讀者反饋學(xué)科排名
作者: Callus 時(shí)間: 2025-3-21 20:24
Epidemiological Evidence of the Relationship Between Diabetes and Dementia, the results for the subtypes of dementia are inconsistent. This review examined the risk of dementia in subjects with diabetes mellitus and discusses the possible mechanism underlying this association. Diabetes mellitus is associated with a 1.5- to 2.5-fold greater risk of dementia among community-作者: RENAL 時(shí)間: 2025-3-22 02:25 作者: 被詛咒的人 時(shí)間: 2025-3-22 05:30
,The Full Spectrum of Alzheimer’s Disease Is Rooted in Metabolic Derangements That Drive Type 3 Diab Aβ deposits. However, other significant abnormalities including neuroinflammation, gliosis, white matter degeneration, non-Aβ microvascular disease, and insulin-related metabolic dysfunction require further study to understand how they could be targeted to more effectively remediate AD. This review作者: 種族被根除 時(shí)間: 2025-3-22 12:07 作者: Deject 時(shí)間: 2025-3-22 15:05 作者: Deject 時(shí)間: 2025-3-22 19:12
,Type II Diabetes Mellitus Accelerates Age-Dependent Aβ Pathology in Cynomolgus Monkey Brain,emains unclear how DM accelerates AD pathology in the brain. Cynomolgus monkey (.) is one of the nonhuman primates used for biomedical research, and we can observe spontaneous formation of AD pathology, such as senile plaques (SPs) and neurofibrillary tangles (NFTs), with the advance of aging. Furth作者: 勛章 時(shí)間: 2025-3-22 22:29 作者: PLUMP 時(shí)間: 2025-3-23 01:37 作者: headway 時(shí)間: 2025-3-23 07:14 作者: 領(lǐng)先 時(shí)間: 2025-3-23 10:47 作者: 微生物 時(shí)間: 2025-3-23 13:51
Diabetes Mellitus978-981-13-3540-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 公豬 時(shí)間: 2025-3-23 20:52 作者: armistice 時(shí)間: 2025-3-23 22:13
https://doi.org/10.1007/0-306-48403-X the results for the subtypes of dementia are inconsistent. This review examined the risk of dementia in subjects with diabetes mellitus and discusses the possible mechanism underlying this association. Diabetes mellitus is associated with a 1.5- to 2.5-fold greater risk of dementia among community-作者: nitroglycerin 時(shí)間: 2025-3-24 06:00 作者: PET-scan 時(shí)間: 2025-3-24 09:09 作者: gerrymander 時(shí)間: 2025-3-24 14:20 作者: Dorsal 時(shí)間: 2025-3-24 17:40
A “Joint+Marginal” Approach in Optimizatione common features, including risk factors, age-associated disease onsets, insulin resistance, impaired glucose metabolism, deregulation of O-GlcNAcylation, chronic oxidative stress, and inflammation. Some of these features, such as insulin resistance, impaired glucose metabolism, and deregulation of作者: 大猩猩 時(shí)間: 2025-3-24 19:21 作者: 披肩 時(shí)間: 2025-3-24 23:29 作者: 地名表 時(shí)間: 2025-3-25 03:35 作者: 提煉 時(shí)間: 2025-3-25 09:15 作者: 切碎 時(shí)間: 2025-3-25 12:51 作者: deceive 時(shí)間: 2025-3-25 17:11 作者: CAGE 時(shí)間: 2025-3-25 22:29
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/d/image/270404.jpg作者: 荒唐 時(shí)間: 2025-3-26 03:15
https://doi.org/10.1007/978-981-13-3540-2Brain-derived insulin; Default network; Glucose/energy metabolism; Mitochondrial dysfunction; Oxidative 作者: Constituent 時(shí)間: 2025-3-26 04:43
Springer Nature Singapore Pte Ltd. 2019作者: 致敬 時(shí)間: 2025-3-26 10:51 作者: 令人不快 時(shí)間: 2025-3-26 15:57
,Type II Diabetes Mellitus Accelerates Age-Dependent Aβ Pathology in Cynomolgus Monkey Brain, as intraneuronal accumulation of enlarged endosomes, was exacerbated in T2DM-affected monkey brains. Since accumulating evidences suggest that endocytic dysfunction is involved in Aβ pathology, T2DM may aggravate age-related endocytic dysfunction, leading to the acceleration of Aβ pathology.作者: 痛打 時(shí)間: 2025-3-26 20:11 作者: 抵押貸款 時(shí)間: 2025-3-26 22:45
,Mammalian Target of Rapamycin at the Crossroad Between Alzheimer’s Disease and Diabetes, Neurology 53(9):1937–1942, 1999; Voisin et al, Rev Med Interne 24(Suppl 3):288s–291s, 2003; Janson et al. Diabetes 53(2):474–481, 2004; Ristow M, J Mol Med (Berl) 82(8):510–529, 2004; Whitmer et al, BMJ 330(7504):1360, 2005, Curr Alzheimer Res 4(2):103–109, 2007; Ohara et al, Neurology 77(12):1126–作者: Insulin 時(shí)間: 2025-3-27 04:20
0065-2598 e presented evidence. In providing answers to the critical questions of whether and why DM is a risk factor for AD, this book will hold appeal for a wide interdisciplinary audience. .978-981-13-3540-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: amenity 時(shí)間: 2025-3-27 07:57
Scheduling on Parallel Processors,t type 3 diabetes is just one of the categories of insulin resistance diseases that can occur independently or overlap with one or more of the others, including type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease.作者: 系列 時(shí)間: 2025-3-27 13:22 作者: Predigest 時(shí)間: 2025-3-27 14:19
https://doi.org/10.1007/978-3-319-43884-9loid accumulation in the brain, indicating different from AD pathology. In addition to insulin resistance, elevated inflammatory cytokines, oxidative stress, and advanced glycation end products were associated with cognitive impairment in this type of dementia. Glycemic controls can improve some dom作者: 性滿足 時(shí)間: 2025-3-27 19:10
The Challenge of a 4°C World by 2100 Neurology 53(9):1937–1942, 1999; Voisin et al, Rev Med Interne 24(Suppl 3):288s–291s, 2003; Janson et al. Diabetes 53(2):474–481, 2004; Ristow M, J Mol Med (Berl) 82(8):510–529, 2004; Whitmer et al, BMJ 330(7504):1360, 2005, Curr Alzheimer Res 4(2):103–109, 2007; Ohara et al, Neurology 77(12):1126–作者: DEVIL 時(shí)間: 2025-3-27 23:57 作者: Ingest 時(shí)間: 2025-3-28 05:31 作者: 陰郁 時(shí)間: 2025-3-28 08:04
Book 2019t opens by discussing the de novo synthesis of insulin in the brain and its functional significance with regard to glucose metabolism and maintenance of neuronal function in the brain. The epidemiological evidence that DM is a risk factor for the development of dementia, including AD as well as vasc作者: 我沒(méi)有命令 時(shí)間: 2025-3-28 12:22
Probing, Inspection, Monitoring balance, as well as plasticity throughout adulthood. Moreover, there are substantial evidence demonstrating that brain insulin is derived from pancreas, neurons, and astrocytes. In this chapter, I reviewed recent progress in roles of insulin in the brain, expression of insulin genes, and multiple origins of the brain insulin.作者: 小步走路 時(shí)間: 2025-3-28 17:07
Scheduling on Parallel Processors,heral diabetes. Such diabetic condition in early stage of AD brain can be exacerbated by peripheral diabetes, namely, through hyperglycemia, hyperinsulinemia, or impaired insulin response. In this chapter, I reviewed mitochondrial dysfunction and oxidative stress in AD brain and discussed how those events are involved in AD pathogenesis.作者: Type-1-Diabetes 時(shí)間: 2025-3-28 22:02
Invariant Semidefinite Programscose metabolism or related pathways, suggesting that these risk factors contribute to the pathogenesis of AD through some common mechanisms. In this chapter, we discuss the roles of ApoE, lipids, and glucose in the pathogenesis of AD by considering their potential interactions.作者: prosperity 時(shí)間: 2025-3-29 01:13
https://doi.org/10.1007/978-3-319-43884-9 in AD development supporting the idea that this neurodegenerative disease is characterized by a pronounced metabolic dysregulation. This chapter is intended to discuss evidence demonstrating the key role of insulin signaling and mitochondrial anomalies in AD.作者: Biomarker 時(shí)間: 2025-3-29 05:36
Origins of Brain Insulin and Its Function, balance, as well as plasticity throughout adulthood. Moreover, there are substantial evidence demonstrating that brain insulin is derived from pancreas, neurons, and astrocytes. In this chapter, I reviewed recent progress in roles of insulin in the brain, expression of insulin genes, and multiple origins of the brain insulin.作者: 埋葬 時(shí)間: 2025-3-29 11:17
Molecular Pathophysiology of Insulin Depletion, Mitochondrial Dysfunction, and Oxidative Stress in heral diabetes. Such diabetic condition in early stage of AD brain can be exacerbated by peripheral diabetes, namely, through hyperglycemia, hyperinsulinemia, or impaired insulin response. In this chapter, I reviewed mitochondrial dysfunction and oxidative stress in AD brain and discussed how those events are involved in AD pathogenesis.作者: 爆米花 時(shí)間: 2025-3-29 12:03
,The Roles of Apolipoprotein E, Lipids, and Glucose in the Pathogenesis of Alzheimer’s Disease,cose metabolism or related pathways, suggesting that these risk factors contribute to the pathogenesis of AD through some common mechanisms. In this chapter, we discuss the roles of ApoE, lipids, and glucose in the pathogenesis of AD by considering their potential interactions.作者: Melanocytes 時(shí)間: 2025-3-29 18:25 作者: remission 時(shí)間: 2025-3-29 20:43
https://doi.org/10.1007/0-306-48403-Xtoxicity, changes in insulin metabolism, and inflammation. The optimal management of these risk factors in early life may be important to prevent future dementia. Furthermore, novel therapeutic strategies will be needed to prevent or reduce the development of dementia in subjects with diabetes mellitus.作者: 起來(lái)了 時(shí)間: 2025-3-30 02:31
https://doi.org/10.1007/978-94-017-9897-6use model, more recently, we have revealed that APO treatment improves neuronal insulin resistance and activates insulin-degrading enzyme (IDE), a major Aβ-degrading enzyme. In this context, recovery of impaired insulin signaling in AD neurons may be a promising therapeutic strategy for AD dementia.作者: 過(guò)分 時(shí)間: 2025-3-30 05:13
