標(biāo)題: Titlebook: Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod; Taro Noguchi Book 2018 Springer Natu [打印本頁(yè)] 作者: 他剪短 時(shí)間: 2025-3-21 16:46
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod影響因子(影響力)
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod影響因子(影響力)學(xué)科排名
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod被引頻次
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod被引頻次學(xué)科排名
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod年度引用
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod年度引用學(xué)科排名
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod讀者反饋
書(shū)目名稱Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod讀者反饋學(xué)科排名
作者: MAG 時(shí)間: 2025-3-21 23:29 作者: 貞潔 時(shí)間: 2025-3-22 03:20 作者: Anhydrous 時(shí)間: 2025-3-22 05:29
https://doi.org/10.1007/978-3-658-07968-0contrast to conventional screening approaches, this process could identify hit compounds from unavailable mirror-image chiral natural products, thus providing unprecedented lead compounds for drug discovery.作者: arthroplasty 時(shí)間: 2025-3-22 11:17 作者: 滔滔不絕的人 時(shí)間: 2025-3-22 13:35 作者: 滔滔不絕的人 時(shí)間: 2025-3-22 20:01 作者: 你敢命令 時(shí)間: 2025-3-23 01:03 作者: 評(píng)論者 時(shí)間: 2025-3-23 05:16
https://doi.org/10.1007/978-3-663-10208-3 MDM2 and MDMX proteins has been established. MDM2 and MDMX are oncoproteins that negatively regulate the activity and stability of the tumor suppressor protein p53. The inhibitors of PPIs of MDM2-p53 and MDMX-p53 represent potential anticancer agents. Affinity-based chemical array screening is one 作者: Truculent 時(shí)間: 2025-3-23 08:52 作者: 青春期 時(shí)間: 2025-3-23 13:08
https://doi.org/10.1007/978-3-658-07968-0contrast to conventional screening approaches, this process could identify hit compounds from unavailable mirror-image chiral natural products, thus providing unprecedented lead compounds for drug discovery.作者: 遠(yuǎn)地點(diǎn) 時(shí)間: 2025-3-23 17:51
Introduction,meric form in nature, mirror-image isomers of them are also potential resources for drug discovery because they have identical physicochemical properties and different biological properties. To screen the mirror-image library of chiral natural products, mirror-image screening strategy has been devel作者: gangrene 時(shí)間: 2025-3-23 20:26
Development of a Mirror-Image Screening System for Chiral Natural Products, MDM2 and MDMX proteins has been established. MDM2 and MDMX are oncoproteins that negatively regulate the activity and stability of the tumor suppressor protein p53. The inhibitors of PPIs of MDM2-p53 and MDMX-p53 represent potential anticancer agents. Affinity-based chemical array screening is one 作者: EWER 時(shí)間: 2025-3-23 23:25 作者: Ventricle 時(shí)間: 2025-3-24 02:42 作者: MODE 時(shí)間: 2025-3-24 08:19 作者: expository 時(shí)間: 2025-3-24 13:09 作者: 協(xié)定 時(shí)間: 2025-3-24 18:50
Development of a Mirror-Image Screening System for Chiral Natural Products,fied from an in-house compound library by chemical array screening. The subsequent fluorescence polarization (FP) assay identified peptidic compounds that inhibited MDM2-p53 and MDMX-p53 interactions.作者: 任命 時(shí)間: 2025-3-24 22:38 作者: 飛來(lái)飛去真休 時(shí)間: 2025-3-25 03:14
Book 2018-image isomers of natural products are promising candidates for novel medicinal resources. . In an effort to identify anticancer agents from the mirror-image library, chemical protein syntheses of some target oncoproteins, MDM2, MDMX and Grb2, and their applications to the chemical array screening p作者: Melanocytes 時(shí)間: 2025-3-25 03:50 作者: 上下連貫 時(shí)間: 2025-3-25 07:38
Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems, for easier preparation. Labeling at the N-terminus or the Ala. residue of the Grb2 SH2 domain provided functional probes to detect binding to a phosphotyrosine-containing peptide. The resulting synthetic-protein-based probes were applied to bioassays including chemical array analysis and enzyme-linked immunosorbent assays (ELISAs).作者: 啞巴 時(shí)間: 2025-3-25 13:49 作者: EXCEL 時(shí)間: 2025-3-25 18:16
https://doi.org/10.1007/978-3-663-10208-3products using a native protein (l-protein) in a mirror. In an effort to identify anticancer agents from the mirror-image natural products, chemical protein syntheses of some target oncoproteins, MDM2, MDMX and Grb2, and their applications to the chemical array screening process were achieved.作者: Anhydrous 時(shí)間: 2025-3-25 22:28 作者: Nucleate 時(shí)間: 2025-3-26 01:53
Book 2018ing mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mirror process. Moreover, as mirror-image isomers including target proteins and natural products are mainly prepared by means of chemical synthesis, th作者: 同義聯(lián)想法 時(shí)間: 2025-3-26 08:23 作者: Suggestions 時(shí)間: 2025-3-26 10:52 作者: 周年紀(jì)念日 時(shí)間: 2025-3-26 15:24
Tools to Trace Truffles in Soiltates, on which state-based assertions can be conveniently formulated. As a result, we get the best of both worlds: on the one hand invariant-style representation of proof knowledge; on the other hand the bisimulation-based formal connection to the code.作者: 坦白 時(shí)間: 2025-3-26 17:59
An International Analysis of Project Delivery Systems for Public Works Projectscontracting as the allocation of obligations, rights and risks among all parties) have been analysed. Then, the equivalence between these PDS and those defined by the Spanish Public Contracts Law has been established and an analysis of PDS used in Spain has been conducted.作者: Endoscope 時(shí)間: 2025-3-26 23:07 作者: 燒烤 時(shí)間: 2025-3-27 01:42
Ulrike Neuerburg? der Beziehung.nur durch Ri?l?ngenwachstum zunehmen, Bild 1. Bruch tritt ein, wenn entweder K. =K. ist, oder wenn die Nennspannung im Restquerschnitt die Zugfestigkeit erreicht. Letzteres gilt selbstverst?ndlich auch für die Ri?ausbreitung bei nicht“konstanten Beanspruchungskenngr??en.作者: countenance 時(shí)間: 2025-3-27 06:46 作者: 走調(diào) 時(shí)間: 2025-3-27 12:44 作者: 蔓藤圖飾 時(shí)間: 2025-3-27 14:47
Introduction,frastructure. It discusses the evolution of urban systems through the integration of the Internet of Things (IoT), big data analytics, and cloud computing, culminating in the emergence of neuromorphic computing. This new computational paradigm mimics the human brain’s neural architecture to enhance 作者: 冰河期 時(shí)間: 2025-3-27 20:00
Einleitung,b und Nutzung zudem ein wichtiger . Zugleich sind Geb?ude eng mit umfassenden überlegungen zu den Notwendigkeiten . verbunden; beispielsweise von mit dem Bau und der Nutzung . . über . sowie .bis hin zur
