標(biāo)題: Titlebook: Designer Receptors Exclusively Activated by Designer Drugs; Gerald Thiel Book 2015 Springer Science+Business Media New York 2015 CNO-stimu [打印本頁] 作者: Hoover 時(shí)間: 2025-3-21 17:14
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書目名稱Designer Receptors Exclusively Activated by Designer Drugs被引頻次
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書目名稱Designer Receptors Exclusively Activated by Designer Drugs年度引用學(xué)科排名
書目名稱Designer Receptors Exclusively Activated by Designer Drugs讀者反饋
書目名稱Designer Receptors Exclusively Activated by Designer Drugs讀者反饋學(xué)科排名
作者: flutter 時(shí)間: 2025-3-21 21:34 作者: JOT 時(shí)間: 2025-3-22 01:42 作者: 大量殺死 時(shí)間: 2025-3-22 05:02
https://doi.org/10.1007/978-3-662-11797-2oorly understood. Here we describe an experimental approach that uses virus-mediated expression of Designer Receptor Exclusively Activated by Designer Drugs (DREADDs) in basal forebrain GABAergic neurons, and behavioral tests, to examine how this inhibitory modulation contributes to olfactory proces作者: GRAVE 時(shí)間: 2025-3-22 10:20 作者: OVER 時(shí)間: 2025-3-22 13:04 作者: OVER 時(shí)間: 2025-3-22 17:51
Designer Receptors Exclusively Activated by Designer Drugs作者: flavonoids 時(shí)間: 2025-3-22 22:31 作者: 人類 時(shí)間: 2025-3-23 04:08
Design and Analysis of an Arrestin-Biased DREADD,ignaling through G protein-independent pathways. To develop a novel tool useful for studying the physiological relevance of these arrestin-dependent signaling pathways, we recently described the development of an M. muscarinic receptor-based DREADD that is no longer able to couple to G proteins but 作者: Harness 時(shí)間: 2025-3-23 08:05 作者: 脫毛 時(shí)間: 2025-3-23 09:53 作者: 光亮 時(shí)間: 2025-3-23 16:19 作者: Toxoid-Vaccines 時(shí)間: 2025-3-23 19:50 作者: 抵制 時(shí)間: 2025-3-23 23:32
Book 2015 measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression 作者: overweight 時(shí)間: 2025-3-24 05:35 作者: 使混合 時(shí)間: 2025-3-24 09:59
Martina Hujslová,Milan Gryndlerssess the equivalence or otherwise of function of a wild-type and corresponding RASSL receptor. The human muscarinic M. acetylcholine receptor is used as the exemplar but similar preliminary studies should be employed before further use, particularly in vivo, of such RASSLs.作者: 走調(diào) 時(shí)間: 2025-3-24 10:55 作者: Harpoon 時(shí)間: 2025-3-24 18:55 作者: Spinal-Fusion 時(shí)間: 2025-3-24 21:27
,Regulation of Gene Transcription Following Stimulation of Gαq-Coupled Designer Receptors,that the reporter genes are embedded into a nucleosomal structure. Recombinant lentiviruses infect mitotic and postmitotic cells such as neurons, thus allowing the analysis of transcriptional changes following the activation of G protein-coupled designer receptors.作者: 歹徒 時(shí)間: 2025-3-25 00:48
0893-2336 ation advice from the expertsThis volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the u作者: Chemotherapy 時(shí)間: 2025-3-25 06:34 作者: 廢墟 時(shí)間: 2025-3-25 11:27
The Use of DREADDs (Designer Receptors Exclusively Activated by Designer Receptors) in Transgenic M describe in detail methods for using DREADDs with transgenic mouse behavioral models. This approach can not only provide insight into the role of specific neural circuits in behavior but also identify potential neuromodulation targets for the treatment of neuropsychiatric disorders.作者: euphoria 時(shí)間: 2025-3-25 12:33 作者: CORE 時(shí)間: 2025-3-25 19:51 作者: 錫箔紙 時(shí)間: 2025-3-25 22:14
Design and Analysis of an Arrestin-Biased DREADD,GPCR function and biology. These mutant muscarinic receptors are unable to bind acetylcholine (ACh), the endogenous muscarinic receptor ligand, but can be efficiently activated by clozapine-N-oxide (CNO), an otherwise pharmacologically inert compound. These CNO-sensitive designer GPCRs (alternative 作者: analogous 時(shí)間: 2025-3-26 02:52
,Regulation of Gene Transcription Following Stimulation of Gαq-Coupled Designer Receptors,imately leads to transcriptional changes. We have designed reporter genes that specifically measure the activities of the stimulus-responsive transcription factors AP-1, CREB, Egr-1, and serum response factor/ternary complex factor. The transcriptional activation potential of CREB and Elk-1 is measu作者: ARENA 時(shí)間: 2025-3-26 06:12 作者: 凹處 時(shí)間: 2025-3-26 09:53
Dissecting Neuronal Circuits Involved in Olfactory-Mediated Behaviors,y, sensory neurons establish synapses with principal neurons of the olfactory bulb (OB), where the earliest stages of odor processing occur. Unlike other sensory systems, output neurons in the OB project to the olfactory cortex bypassing the thalamus. Therefore, neural circuits in the OB, and odor p作者: 感染 時(shí)間: 2025-3-26 13:08
The Use of DREADDs (Designer Receptors Exclusively Activated by Designer Receptors) in Transgenic Mthe brains of awake, behaving mice. Here we review the pros and cons of DREADDs relative to other genetically encoded neuromodulation technologies and describe in detail methods for using DREADDs with transgenic mouse behavioral models. This approach can not only provide insight into the role of spe作者: CAPE 時(shí)間: 2025-3-26 19:25 作者: bacteria 時(shí)間: 2025-3-26 22:20 作者: Incompetent 時(shí)間: 2025-3-27 03:38
DREADDs in ,, of this system include powerful genetic methods, sophisticated behaviors, and conservation of fundamental aspects of development and physiology with mammals. There have been several methods of conditional control of neuronal activity developed for the fly; however, they are primarily switch-like, a作者: 滋養(yǎng) 時(shí)間: 2025-3-27 07:57 作者: 走路左晃右晃 時(shí)間: 2025-3-27 11:00
978-1-4939-4957-1Springer Science+Business Media New York 2015作者: 畸形 時(shí)間: 2025-3-27 13:44 作者: 脆弱吧 時(shí)間: 2025-3-27 20:53 作者: Anticlimax 時(shí)間: 2025-3-27 23:58
Fungicide Resistance in Plant Pathogensimately leads to transcriptional changes. We have designed reporter genes that specifically measure the activities of the stimulus-responsive transcription factors AP-1, CREB, Egr-1, and serum response factor/ternary complex factor. The transcriptional activation potential of CREB and Elk-1 is measu作者: motivate 時(shí)間: 2025-3-28 03:15
https://doi.org/10.1007/978-4-431-55642-8h human history by examining how it has shaped our genes, cultures, and landscapes. Yet, despite the shared familiarity of eating, the neural circuits underlying the motivational processes underlying shifts in appetite have remained elusive due to a lack of methods sensitive enough to probe defined 作者: adj憂郁的 時(shí)間: 2025-3-28 08:18 作者: 道學(xué)氣 時(shí)間: 2025-3-28 11:25
Spezieller Teil: Chemie der Fungizidethe brains of awake, behaving mice. Here we review the pros and cons of DREADDs relative to other genetically encoded neuromodulation technologies and describe in detail methods for using DREADDs with transgenic mouse behavioral models. This approach can not only provide insight into the role of spe作者: chandel 時(shí)間: 2025-3-28 15:56 作者: CHOP 時(shí)間: 2025-3-28 20:10 作者: Pseudoephedrine 時(shí)間: 2025-3-28 23:13 作者: 污點(diǎn) 時(shí)間: 2025-3-29 04:33
Designer Receptors Exclusively Activated by Designer Drugs978-1-4939-2944-3Series ISSN 0893-2336 Series E-ISSN 1940-6045 作者: Contend 時(shí)間: 2025-3-29 09:10
Gerald ThielIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts作者: 叢林 時(shí)間: 2025-3-29 11:52
Neuromethodshttp://image.papertrans.cn/d/image/268891.jpg