標題: Titlebook: Design and Analysis of Vaccine Studies; M. Elizabeth Halloran,Ira M. Longini,Claudio J. St Book 2010 Springer-Verlag New York 2010 Biostat [打印本頁] 作者: 過分愛國主義 時間: 2025-3-21 18:30
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書目名稱Design and Analysis of Vaccine Studies讀者反饋
書目名稱Design and Analysis of Vaccine Studies讀者反饋學科排名
作者: Capture 時間: 2025-3-21 22:16 作者: 幻想 時間: 2025-3-22 01:53 作者: Intervention 時間: 2025-3-22 05:02 作者: Entropion 時間: 2025-3-22 10:22 作者: 只有 時間: 2025-3-22 13:39 作者: 只有 時間: 2025-3-22 19:05
Kousha Etessami,Mihalis Yannakakis vaccine is 90%. You might then wonder if that means that the vaccine reduces your probability of contracting the infection (or disease) by 0.90 at each exposure to infection. In other words, you still might have a finite probability of contracting the infection or disease each time you were exposed作者: Sputum 時間: 2025-3-22 22:38 作者: 考得 時間: 2025-3-23 04:39 作者: CLEFT 時間: 2025-3-23 06:33
From Rule-Based to Automata-Based Testingr defining exposure to infection in vaccine studies as early as the 1930s in evaluating the efficacy of pertussis vaccines (Kendrick and Eldering 1939). In addition to evaluating vaccine efficacy, household studies have been used to learn about transmission and natural history of many infections. As作者: 共和國 時間: 2025-3-23 13:34
Spatial Model Checking for Smart Stationserves as a source of initial infection within households as well as possible further cases in the household. Infected household members can infect others in the household. To start, we discuss general aspects of these models. All models in this chapter are variants of the basic models presented in t作者: RENIN 時間: 2025-3-23 15:10 作者: Lime石灰 時間: 2025-3-23 20:29
Lecture Notes in Computer Sciencet protective effects, even in unvaccinated individuals. The public health importance of a vaccine is related to the direct protection of the vaccinated individuals as well as the indirect protection conferred by increased herd immunity at the population level. In recent years, interest in estimating作者: figure 時間: 2025-3-24 01:44 作者: 不近人情 時間: 2025-3-24 03:18 作者: 別炫耀 時間: 2025-3-24 09:55
Statistics for Biology and Healthhttp://image.papertrans.cn/d/image/268518.jpg作者: Paraplegia 時間: 2025-3-24 11:19
Analysis of Independent Households, estimate vaccine efficacy based on the conventional secondary attack rate. We also consider the estimation of indirect effects of vaccination using household studies. The Reed–Frost model in Chapter 4 is another example of a model that assumes households or transmission units are independent.作者: 違反 時間: 2025-3-24 15:10
https://doi.org/10.1007/978-0-387-68636-3Biostatistics; Epidemiology; Infectious disease epidemiology; infection; infectious; infectious disease; i作者: Genome 時間: 2025-3-24 21:17
978-1-4614-2488-8Springer-Verlag New York 2010作者: sinoatrial-node 時間: 2025-3-25 00:56
Design and Analysis of Vaccine Studies978-0-387-68636-3Series ISSN 1431-8776 Series E-ISSN 2197-5671 作者: 羊齒 時間: 2025-3-25 03:50
Lecture Notes in Computer Science estimate vaccine efficacy based on the conventional secondary attack rate. We also consider the estimation of indirect effects of vaccination using household studies. The Reed–Frost model in Chapter 4 is another example of a model that assumes households or transmission units are independent.作者: Benzodiazepines 時間: 2025-3-25 08:23
Book 2010is in understanding and estimating all of these effects. This book presents a unified conceptual framework of the different effects of vaccination at the individual and at the population level. The book covers many different vaccine effects, including vaccine efficacy for susceptibility, for disease作者: Acclaim 時間: 2025-3-25 11:45
1431-8776 challenge is in understanding and estimating all of these effects. This book presents a unified conceptual framework of the different effects of vaccination at the individual and at the population level. The book covers many different vaccine effects, including vaccine efficacy for susceptibility, f作者: 包租車船 時間: 2025-3-25 19:28
https://doi.org/10.1007/978-981-99-7584-6ough the framework is not exhaustive, many designs not considered explicitly in this overview are special cases of these general designs. Our primary concern in this chapter is conceptual. Details of study design and methods of estimation and inference are left to following chapters.作者: TOXIC 時間: 2025-3-25 23:35
Overview of Vaccine Effects and Study Designs,ough the framework is not exhaustive, many designs not considered explicitly in this overview are special cases of these general designs. Our primary concern in this chapter is conceptual. Details of study design and methods of estimation and inference are left to following chapters.作者: Supplement 時間: 2025-3-26 03:43
Introduction and Examples,d to the unvaccinated group:.Historically, interest focused on evaluating protective effects of vaccination. Study designs and statistical analysis played a role even with early immunizations. In the November 5, 1904, issue of the ., Karl Pearson published a criticism of the Antityphoid Committee’s 作者: photopsia 時間: 2025-3-26 06:28
Overview of Vaccine Effects and Study Designs,esigns to estimate them. This framework provides a structure for thinking about the different vaccine effects of interest and how they are related to one another. We present different versions of vaccine efficacy and effectiveness as one minus some measure of relative risk, ...We focus on the relati作者: Infantry 時間: 2025-3-26 11:06
Immunology and Early Phase Trials,se that mimics natural infection or tries to do even better than our response to a pathogen. Vaccination induces an immune response in the individual vaccinated. A population of hosts has a collective level of immunity that results from the level of immunity in the individuals that compose it. The c作者: Neutral-Spine 時間: 2025-3-26 16:18
Binomial and Stochastic Transmission Models,studies. It can influence our choice of interventions. In this chapter and the next we introduce transmission models necessary for estimating and understanding the effects of vaccination. In this chapter, we present the binomial model and the chain binomial model. These models are central to formula作者: Arresting 時間: 2025-3-26 17:43
and Deterministic Models,r her infectious period in a large, completely susceptible population. For example, if . = 5 for mumps in a human population, then one infectious person in that population would be expected to produce five new secondary infectious cases if the population were completely susceptible. If he produced t作者: Cougar 時間: 2025-3-26 21:58
Evaluating Protective Effects of Vaccination,y. Generally, interest has been in the ability of vaccination to prevent or to ameliorate disease rather than to prevent infection (Clements-Mann 1998). Ascertainment of cases is often done by finding suspected cases in the population under study in people who exhibit a set of symptoms. The suspecte作者: 改進 時間: 2025-3-27 05:02
Modes of Action and Time-Varying VE, vaccine is 90%. You might then wonder if that means that the vaccine reduces your probability of contracting the infection (or disease) by 0.90 at each exposure to infection. In other words, you still might have a finite probability of contracting the infection or disease each time you were exposed作者: 一再困擾 時間: 2025-3-27 06:01 作者: 棲息地 時間: 2025-3-27 09:26 作者: 廢墟 時間: 2025-3-27 16:37
Household-Based Studies,r defining exposure to infection in vaccine studies as early as the 1930s in evaluating the efficacy of pertussis vaccines (Kendrick and Eldering 1939). In addition to evaluating vaccine efficacy, household studies have been used to learn about transmission and natural history of many infections. As作者: BUST 時間: 2025-3-27 20:12 作者: Cardiac-Output 時間: 2025-3-28 01:53
Analysis of Independent Households, estimate vaccine efficacy based on the conventional secondary attack rate. We also consider the estimation of indirect effects of vaccination using household studies. The Reed–Frost model in Chapter 4 is another example of a model that assumes households or transmission units are independent.作者: innovation 時間: 2025-3-28 03:22 作者: Inexorable 時間: 2025-3-28 07:51 作者: Intruder 時間: 2025-3-28 11:06
Surrogates of Protection, immune response to vaccination predictive of protection from infection and disease were available, it would help to avoid new large trials and facilitate getting new products and formulations approved. An immunological surrogate of protection could reduce the sample size or shorten the duration of 作者: novelty 時間: 2025-3-28 18:37
M. Elizabeth Halloran,Ira M. Longini,Claudio J. St作者: Ledger 時間: 2025-3-28 19:02
Introduction and Examples, similar range. He compared these values with his analysis of the relation of recovery from smallpox with smallpox vaccination, which were in the range 0.576 and 0.769. Although he demurred somewhat due to his lack of knowledge about typhoid, he wrote that the results were such as “would justify sus作者: Brittle 時間: 2025-3-28 23:48 作者: locus-ceruleus 時間: 2025-3-29 06:54
Binomial and Stochastic Transmission Models,on a number produced by a random number generator described later..In Chapter 5 we present simple differential equation transmission models that are generally deterministic. That is, every time the equations are solved, the same answer is obtained. This approach is essential to understanding large c作者: 洞穴 時間: 2025-3-29 09:01 作者: Nausea 時間: 2025-3-29 11:34
Evaluating Protective Effects of Vaccination,ns in asymptomatic people, an active follow-up method of testing asymptomatic people is needed..In this chapter we consider estimation and inference for direct protective effects of vaccination, VE. and VE., in studies that do not condition on exposure to infection.We consider aspects of the design 作者: innate 時間: 2025-3-29 17:27
Modes of Action and Time-Varying VE,% of the vaccinated people. Would you behave differently if you knew which of these possibilities were actually true? Would it make a difference if the vaccine were against a disease with a high case fatality ratio?Would it make a difference if the efficacy were 60% rather than 90%?.In Chapter 6, va作者: angina-pectoris 時間: 2025-3-29 22:06 作者: 調(diào)整 時間: 2025-3-30 01:39 作者: micronized 時間: 2025-3-30 06:21 作者: reserve 時間: 2025-3-30 12:14
Analysis of Households in Communities,t condition on exposure to infection. The second is a conditional parameter. The models can be formulated in discrete time or continuous time. For some data structures, such as data on sexual contacts, contacts can be substituted for time. Models formulated in discrete time have a parameter for the 作者: 鞏固 時間: 2025-3-30 12:38 作者: 漂亮才會豪華 時間: 2025-3-30 18:18
Randomization and Baseline Transmission,roups. Thus, the treatment groups are seen as comparable. Baseline transmission, pre-existing immunity, and individual responsiveness are examples of possibly relevant factors. For these reasons, randomization, in addition to double-masking, are usually proposed as good research practices for valid 作者: CURT 時間: 2025-3-30 23:44 作者: chiropractor 時間: 2025-3-31 01:00 作者: 劇毒 時間: 2025-3-31 05:24
Calin Belta,Boyan Yordanov,Ebru Aydin Golterplay between individual and population level immunity is maintained through the dependent happenings..The immune response is also the source of many safety considerations of vaccination. Before a vaccine can be shown efficacious against infection or disease in a large-scale field study, it must b
