標(biāo)題: Titlebook: Dengue and Zika: Control and Antiviral Treatment Strategies; Rolf Hilgenfeld,Subhash G. Vasudevan Book 2018 Springer Nature Singapore Pte [打印本頁(yè)] 作者: panache 時(shí)間: 2025-3-21 18:17
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies影響因子(影響力)
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies影響因子(影響力)學(xué)科排名
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies被引頻次
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies被引頻次學(xué)科排名
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies年度引用
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies年度引用學(xué)科排名
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies讀者反饋
書(shū)目名稱Dengue and Zika: Control and Antiviral Treatment Strategies讀者反饋學(xué)科排名
作者: 蝕刻術(shù) 時(shí)間: 2025-3-21 22:27 作者: 性行為放縱者 時(shí)間: 2025-3-22 03:40 作者: Entropion 時(shí)間: 2025-3-22 08:20
Coordination through Communicationptember 2016. The opportunities and gaps for developing therapeutic countermeasures, to take advantage of the high-resolution cryo-electron microscopy structures of dengue and Zika viruses as well as the novel features of NS1 revealed by the 3D structures, were deliberated.作者: 弄污 時(shí)間: 2025-3-22 12:07 作者: 清醒 時(shí)間: 2025-3-22 13:14 作者: 清醒 時(shí)間: 2025-3-22 20:52
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/d/image/265532.jpg作者: 引導(dǎo) 時(shí)間: 2025-3-22 22:11
https://doi.org/10.1007/978-981-10-8727-1Licensed vaccine; Efficacious drugs; Vector control; Antivirals; Protective efficacy作者: compassion 時(shí)間: 2025-3-23 03:25 作者: 匯總 時(shí)間: 2025-3-23 07:38 作者: nettle 時(shí)間: 2025-3-23 11:51 作者: 小步走路 時(shí)間: 2025-3-23 16:45 作者: Notify 時(shí)間: 2025-3-23 21:59 作者: 善變 時(shí)間: 2025-3-24 00:35
Networked Fractional-order Systems distributed and it is estimated over a third of the world’s population is at risk of infection [.]. While the majority of infections are asymptomatic, DENV infection can cause a spectrum of disease, from mild flu-like symptoms, to the more severe DENV hemorrhagic fever and shock syndrome [.]. Over 作者: WAIL 時(shí)間: 2025-3-24 04:28
Collective Periodic Motion Coordinationn countries where it has become strongly associated with congenital birth defects leading to severe cranial malformations and neurological conditions. The increase in number of case of microcephaly in newborn children associated with ZIKV infection triggered the World Health Organization to declare 作者: gerontocracy 時(shí)間: 2025-3-24 09:06 作者: 掙扎 時(shí)間: 2025-3-24 10:53 作者: 憤憤不平 時(shí)間: 2025-3-24 17:01 作者: 向下 時(shí)間: 2025-3-24 20:43 作者: Hyperlipidemia 時(shí)間: 2025-3-25 02:40 作者: 結(jié)束 時(shí)間: 2025-3-25 05:57 作者: Apoptosis 時(shí)間: 2025-3-25 10:42
Monotone Games for Cognitive Radio Systemsents that alleviate symptoms in patients are of considerable interest. Among others, the flaviviral protease NS2B-NS3 is a promising drug target to inhibit viral replication. Flaviviral proteases share a high degree of structural similarity and substrate-recognition profile, which may facilitate a s作者: Reclaim 時(shí)間: 2025-3-25 14:47 作者: 織物 時(shí)間: 2025-3-25 16:16 作者: Loathe 時(shí)間: 2025-3-25 21:12
Programming of Embedded Systemsercome the natural resistance of mice to non-encephalitic flaviviruses. Conditional IFNAR mice and non-human primates (NHP) are useful immuno-competent models. Sterile immunity after dengue vaccination is not observed in NHPs. Placental and fetal development in NHPs is similar to humans, facilitatin作者: 鉆孔 時(shí)間: 2025-3-26 02:29 作者: commensurate 時(shí)間: 2025-3-26 06:44
Akhan Almagambetov,Senem Velipasalarglucosidases whose sequential action permits entry in this pathway are the targets of glucomimetic inhibitors. Knowledge of the molecular details of the ER α-glucosidase II (α-Glu II) structure was limited. We determined crystal structures of a trypsinolytic fragment of murine α-Glu II, alone and in作者: 粗鄙的人 時(shí)間: 2025-3-26 10:00 作者: 演講 時(shí)間: 2025-3-26 16:20
Containment Control with Multiple Leaderstoxic activity through recognition by the innate immune receptor TLR4, mimicking the bacterial endotoxin LPS. This monograph covers the background underpinning these new findings and discusses new avenues for antiviral and vaccine intervention.作者: 淡紫色花 時(shí)間: 2025-3-26 19:12 作者: IST 時(shí)間: 2025-3-26 23:10 作者: 縮影 時(shí)間: 2025-3-27 04:10
Signals and Communication Technologyic changes in vector-host transmission cycles that result in the human population becoming significantly more exposed, will help to prepare us for the next emerging epidemic/pandemic. This Chapter seeks to provide a brief overview of the arboviruses, their mode of transmission and some of the known factors that drive their expansion.作者: Cholecystokinin 時(shí)間: 2025-3-27 08:59
Distributed Embedded Smart Camerasponses to dengue virus vaccination. As our understanding of the diverse functions of NK cell has advanced, it has become increasingly clear that human NK cell responses to viral infections are more complicated than initially recognized.作者: 細(xì)微的差異 時(shí)間: 2025-3-27 09:40
Arboviruses: A Family on the Move,ic changes in vector-host transmission cycles that result in the human population becoming significantly more exposed, will help to prepare us for the next emerging epidemic/pandemic. This Chapter seeks to provide a brief overview of the arboviruses, their mode of transmission and some of the known factors that drive their expansion.作者: Frequency 時(shí)間: 2025-3-27 15:10 作者: Diastole 時(shí)間: 2025-3-27 21:20
Distributed Embedded Control Systemsthat mapped to the N pocket. This is the first report of a class of pan-serotype and cell-active DENV RdRp inhibitors and provides a significant opportunity for rational design of novel therapeutics against this proven antiviral target.作者: 遺傳學(xué) 時(shí)間: 2025-3-27 22:28 作者: Benign 時(shí)間: 2025-3-28 02:46
Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Frathat mapped to the N pocket. This is the first report of a class of pan-serotype and cell-active DENV RdRp inhibitors and provides a significant opportunity for rational design of novel therapeutics against this proven antiviral target.作者: Rejuvenate 時(shí)間: 2025-3-28 09:23
Structural Insights into the Broad-Spectrum Antiviral Target Endoplasmic Reticulum Alpha-Glucosidasbstrate specificity. These crystal structures and hydrogen-deuterium exchange mass spectrometry of the murine ER alpha glucosidase II heterodimer uncover the quaternary arrangement of the enzyme’s α- and β-subunits, and suggest a conformational rearrangement of ER α-Glu II upon association of the enzyme with client glycoproteins.作者: 偽造者 時(shí)間: 2025-3-28 13:37
0065-2598 t the end of each presentation – “the salt in the soup”.Show.This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, patho作者: 沙漠 時(shí)間: 2025-3-28 16:13 作者: overture 時(shí)間: 2025-3-28 22:30
0065-2598 ntations. These have been transcribed and appended to the end of the relevant chapters, and they form the “salt in the soup” of this book..978-981-13-4225-7978-981-10-8727-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: Excitotoxin 時(shí)間: 2025-3-29 02:45 作者: Neutropenia 時(shí)間: 2025-3-29 04:51
Reliable Serological Testing for the Diagnosis of Emerging Infectious Diseases,is: direct pathogen detection and the determination of specific antibodies. Serological tests provide a longer diagnostic window than direct methods, and are suitable for diagnosing acute and past infections, for disease surveillance and for vaccination monitoring. ELISA and indirect immunofluoresce作者: Anecdote 時(shí)間: 2025-3-29 07:20
The Molecular Specificity of the Human Antibody Response to Dengue Virus Infections,ns but not others [.]. In light of unexpected results from DENV vaccine trials, in this chapter we will review recent discoveries about the human antibody response to natural DENV infection and discuss the relevance of this work to understanding vaccine performance.作者: JOT 時(shí)間: 2025-3-29 11:42
Structures of Zika Virus E & NS1: Relations with Virus Infection and Host Immune Responses,tion, pathogenesis, and host immune response which contributes significantly to the control of the virus infection. The E and NS1 proteins of ZIKV are the major targets for neutralizing and protective antibodies. In this chapter, we mainly focus on recent research on the crystal structures of the ZI作者: refraction 時(shí)間: 2025-3-29 16:04 作者: 管理員 時(shí)間: 2025-3-29 22:36 作者: 陳列 時(shí)間: 2025-3-30 03:32 作者: abnegate 時(shí)間: 2025-3-30 07:29
Establishment and Application of Flavivirus Replicons,to susceptible cells. In 1989, the first infectious flavivirus RNA was transcribed from full-length cDNA templates of yellow fever virus (YFV) facilitating molecular genetic analyses of this virus. In addition to the production of infectious recombinant viruses, reverse genetics can also be used to 作者: 撫育 時(shí)間: 2025-3-30 11:50 作者: 誘拐 時(shí)間: 2025-3-30 16:14 作者: 悠然 時(shí)間: 2025-3-30 18:54
Understanding the Human T Cell Response to Dengue Virus,作者: finale 時(shí)間: 2025-3-30 22:47
Dengue and Zika: Control and Antiviral Treatment Strategies作者: Fulsome 時(shí)間: 2025-3-31 03:54 作者: 逗留 時(shí)間: 2025-3-31 08:23 作者: 先兆 時(shí)間: 2025-3-31 11:50
https://doi.org/10.1007/0-387-30394-4is: direct pathogen detection and the determination of specific antibodies. Serological tests provide a longer diagnostic window than direct methods, and are suitable for diagnosing acute and past infections, for disease surveillance and for vaccination monitoring. ELISA and indirect immunofluoresce作者: 不如屎殼郎 時(shí)間: 2025-3-31 15:24
Networked Fractional-order Systemsns but not others [.]. In light of unexpected results from DENV vaccine trials, in this chapter we will review recent discoveries about the human antibody response to natural DENV infection and discuss the relevance of this work to understanding vaccine performance.作者: 審問(wèn) 時(shí)間: 2025-3-31 21:21 作者: constitutional 時(shí)間: 2025-4-1 00:03
Hierarchical Production Planningg the innate immune response. NS4B binds to the NS2B-NS3 protease-helicase, which itself interacts with the NS5 methyl-transferase polymerase. We present an overview of recent structural and functional data that augment our understanding of how viral RNA is replicated by dengue virus. We focus on st作者: vitrectomy 時(shí)間: 2025-4-1 04:16 作者: chemoprevention 時(shí)間: 2025-4-1 07:47 作者: 諷刺 時(shí)間: 2025-4-1 10:24
Distributed Decision Making and Controlto susceptible cells. In 1989, the first infectious flavivirus RNA was transcribed from full-length cDNA templates of yellow fever virus (YFV) facilitating molecular genetic analyses of this virus. In addition to the production of infectious recombinant viruses, reverse genetics can also be used to 作者: 門閂 時(shí)間: 2025-4-1 14:53
Monotone Games for Cognitive Radio Systemshowever, with highly compromised drug-likeness. With some exceptions, the antiviral cellular activity of most of the reported compounds have been patchy and insufficient for further development. Recent progress has been made in the elucidation of inhibitor binding using different structural methods.作者: 迅速飛過(guò) 時(shí)間: 2025-4-1 18:34 作者: 可用 時(shí)間: 2025-4-1 23:52
Arboviruses: A Family on the Move,st 30?years, the emergence and/or resurgence of arboviruses have posed a considerable global health threat. The ongoing geographical expansion of the dengue viruses (DENV), along with the explosive outbreaks of West Nile virus (WNV), Chikungunya virus (CHIKV) and more recently, Zika virus (ZIKV) hav作者: 起草 時(shí)間: 2025-4-2 04:39
Historical Perspective of Arboviruses in Mozambique and Its Implication for Current and Future Epid quite scarce although the frequency of outbreaks caused by arboviruses is rapidly increasing. Outbreaks of dengue fever have been reported in Mozambique, Angola and Tanzania and a recent unprecedented outbreak of Yellow fever has been recorded in Angola. These new outbreaks collectively suggest tha作者: Outspoken 時(shí)間: 2025-4-2 08:29
Reliable Serological Testing for the Diagnosis of Emerging Infectious Diseases, virus (ZIKV) is currently spreading in the Americas, while dengue virus (DENV) and chikungunya virus (CHIKV) have already become firmly established in most tropical and also many non-tropical regions. ZIKV, DENV and CHIKV overlap in their endemic areas and cause similar clinical symptoms, especiall
