標(biāo)題: Titlebook: Delta Opioid Receptor Pharmacology and Therapeutic Applications; Emily M. Jutkiewicz Book 2018 Springer International Publishing AG, part [打印本頁] 作者: Orthosis 時間: 2025-3-21 19:22
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書目名稱Delta Opioid Receptor Pharmacology and Therapeutic Applications讀者反饋學(xué)科排名
作者: 平 時間: 2025-3-21 23:41
Multifunctional Opioid Ligands,the treatment of many different conditions, including pain, depression, and addiction. However, stimulation or blockade of any one opioid receptor type often leads to on-target adverse effects that limit the clinical utility of a selective opioid agonist or antagonist. Literature precedent suggests 作者: Corporeal 時間: 2025-3-22 01:55 作者: cruise 時間: 2025-3-22 05:36 作者: encyclopedia 時間: 2025-3-22 10:06
Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons, somatosensory experiences, from shooting pain to pleasant touch. In recent years, the identification of dozens of genetic markers specifically expressed by subpopulations of DRG neurons has dramatically improved our understanding of this diversity and provided the tools to manipulate their activity作者: Mercurial 時間: 2025-3-22 14:58 作者: Mercurial 時間: 2025-3-22 18:25 作者: 環(huán)形 時間: 2025-3-22 22:16 作者: instulate 時間: 2025-3-23 02:33
Delta Opioid Receptors and Modulation of Mood and Emotion,gh opioids have long been known to regulate mood states, the use of opioids to treat depression is rarely discussed. This chapter explores the preclinical and clinical evidence supporting the antidepressant-like effects of opioid ligands, and in particular, delta opioid receptor (DOR) agonists. DOR 作者: Introduction 時間: 2025-3-23 07:48 作者: Coeval 時間: 2025-3-23 12:46 作者: 館長 時間: 2025-3-23 16:43 作者: Adenocarcinoma 時間: 2025-3-23 19:13
Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders,uch as stroke and Parkinson’s Disease. In particular, delta opioid receptors (DORs) have been elucidated as a therapeutically distinguished subset of opioid receptors and a compelling target for novel intervention techniques. Research is progressively shedding light on the underlying mechanism of DO作者: 暫停,間歇 時間: 2025-3-23 23:09 作者: 潰爛 時間: 2025-3-24 02:36 作者: Bone-Scan 時間: 2025-3-24 09:56
Emily M. JutkiewiczDiscusses emerging knowledge about the biological function of the delta opioid receptor.Describes therapeutic potential of the delta opioid receptor system.Describes unique trafficking and signaling p作者: graphy 時間: 2025-3-24 11:16
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/d/image/265015.jpg作者: angina-pectoris 時間: 2025-3-24 18:07
Delta Opioid Receptor Pharmacology and Therapeutic Applications978-3-319-95133-1Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: 泥瓦匠 時間: 2025-3-24 19:17
https://doi.org/10.1007/978-3-319-95133-1CNS-related diseases; Enkephalin; biased agonism; drug development; pain, emotion and addiction; receptor作者: amnesia 時間: 2025-3-25 01:37 作者: COWER 時間: 2025-3-25 04:21
Die Mikroskopie der lebenden IrisR is now receiving increasing attention, and there has been progress in the synthesis of better novel ligands. The discovery of a selective receptor DOR antagonist, naltrindole (NTI), stimulated the design and synthesis of (±)TAN-67, which was designed based on the message-address concept and the ac作者: 空中 時間: 2025-3-25 09:40 作者: 雕鏤 時間: 2025-3-25 11:40
Die Stellung der Frau als Polizeibeamtin, same extent as that following identification of the opiate receptor(s) and subsequent isolation of endogenous morphine-like peptides. There is overwhelming evidence in animals and in human that opioids are involved in behaviorally relevant issues such as the modulation of pain, the response to stre作者: intention 時間: 2025-3-25 17:51
https://doi.org/10.1007/978-3-322-84112-4 disorders, chronic pain, and migraine. A major challenge to the development of these compounds is that, like many G-protein coupled receptors (GPCRs), agonists at the δOR can induce very different signaling and receptor trafficking events. This concept, known as ligand-directed signaling, functiona作者: 額外的事 時間: 2025-3-25 23:21 作者: 神圣在玷污 時間: 2025-3-26 03:47
https://doi.org/10.1007/978-3-663-13529-6pioid receptor types can physically associate to form heteromers. Owing to their constituent monomers’ involvement in analgesia, mu/delta opioid receptor (M/DOR) heteromers have been a particular focus of attention. Understandings of the physiological relevance and indisputable proof of M/DOR format作者: 邊緣 時間: 2025-3-26 04:47 作者: 并排上下 時間: 2025-3-26 09:44 作者: SPURN 時間: 2025-3-26 15:09 作者: Blood-Vessels 時間: 2025-3-26 17:24
https://doi.org/10.1007/978-3-662-26146-0tigating how alcohol directly impacts DOR pharmacology and of early studies indicating DOR modulation of alcohol behavior. We will offer a brief summary of the different animal species used in alcohol studies investigating DORs followed by a broader overview of the types of alcohol behaviors modulat作者: 過度 時間: 2025-3-26 22:09 作者: 陳列 時間: 2025-3-27 04:49
Bernd Guggenberger,Klaus Hansenrine, serotonin, acetylcholine, and glutamate systems. Loss of these transmitter systems initiates a cascade of neurological deficits beginning with motor function and ending with dementia. Current therapies primarily address the motor symptoms of the disease via dopamine replacement therapy. Exogen作者: 臨時抱佛腳 時間: 2025-3-27 06:46
Bernd Guggenberger,Klaus Hansenuch as stroke and Parkinson’s Disease. In particular, delta opioid receptors (DORs) have been elucidated as a therapeutically distinguished subset of opioid receptors and a compelling target for novel intervention techniques. Research is progressively shedding light on the underlying mechanism of DO作者: vocation 時間: 2025-3-27 13:02 作者: 粘連 時間: 2025-3-27 15:32
Auf der Suche nach der neuen Mitteas pain or itch, and unfavorable cosmetic outcomes. Moreover, some wounds simply fail to heal and become a chronic burden for the sufferer. Understanding the mechanisms underlying wound healing and the concomitant sensory disorders and how they might be manipulated for therapeutic benefit has attrac作者: peptic-ulcer 時間: 2025-3-27 21:24 作者: intrigue 時間: 2025-3-28 01:05
Delta Opioid Receptor Pharmacology and Therapeutic Applications作者: 動作謎 時間: 2025-3-28 03:06
Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinannt agonist activity following systemic administration. Interestingly, KNT-127 produced no convulsive effects, unlike prototype DOR agonists. The KNT-127 type derivatives with a quinolinomorphinan structure are expected to be promising candidates for the development of therapeutic DOR agonists.作者: 類似思想 時間: 2025-3-28 07:30 作者: Mast-Cell 時間: 2025-3-28 12:36 作者: 不能逃避 時間: 2025-3-28 14:49 作者: 一條卷發(fā) 時間: 2025-3-28 22:03
Genetic Variation and Human Disease,easingly well-defined mechanism by which the variant allele reduces production of the beta-amyloid plaques associated with the disease. Additional studies of . variants are necessary to replicate current findings and to delineate the functional roles of relevant polymorphisms.作者: defendant 時間: 2025-3-29 02:05 作者: conquer 時間: 2025-3-29 04:12 作者: 少量 時間: 2025-3-29 08:10 作者: 權(quán)宜之計 時間: 2025-3-29 13:23
Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders, to reduce cell death following ischemic events. Current research is working to reveal the complex mechanisms of DADLE’s neuroprotective properties. Ultimately, our knowledge of the DOR receptors and agonists has made the opioid system a promising target for therapeutic intervention in many neurolog作者: Pathogen 時間: 2025-3-29 17:57
0171-2004 DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.978-3-030-06980-3978-3-319-95133-1Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: fender 時間: 2025-3-29 22:08 作者: cardiac-arrest 時間: 2025-3-30 02:46 作者: multiply 時間: 2025-3-30 05:53
https://doi.org/10.1007/978-3-322-84112-4he long-term adaptations induced by chronic drug treatment. A better understanding of the specific signaling cascades that regulate these differential behavioral effects would help to guide rational drug design, ultimately resulting in δOR agonists with fewer adverse effects.作者: frugal 時間: 2025-3-30 11:57 作者: Bouquet 時間: 2025-3-30 12:42
https://doi.org/10.1007/978-3-663-13529-6easingly well-defined mechanism by which the variant allele reduces production of the beta-amyloid plaques associated with the disease. Additional studies of . variants are necessary to replicate current findings and to delineate the functional roles of relevant polymorphisms.作者: 表兩個 時間: 2025-3-30 17:38 作者: QUAIL 時間: 2025-3-30 22:34
