標題: Titlebook: Delivery Systems for Peptide Drugs; S. S. Davis,Lisbeth Illum,E. Tomlinson Book 1986 Springer Science+Business Media New York 1986 absorpt [打印本頁] 作者: hierarchy 時間: 2025-3-21 19:50
書目名稱Delivery Systems for Peptide Drugs影響因子(影響力)
書目名稱Delivery Systems for Peptide Drugs影響因子(影響力)學科排名
書目名稱Delivery Systems for Peptide Drugs網(wǎng)絡公開度
書目名稱Delivery Systems for Peptide Drugs網(wǎng)絡公開度學科排名
書目名稱Delivery Systems for Peptide Drugs被引頻次
書目名稱Delivery Systems for Peptide Drugs被引頻次學科排名
書目名稱Delivery Systems for Peptide Drugs年度引用
書目名稱Delivery Systems for Peptide Drugs年度引用學科排名
書目名稱Delivery Systems for Peptide Drugs讀者反饋
書目名稱Delivery Systems for Peptide Drugs讀者反饋學科排名
作者: 爭吵 時間: 2025-3-21 23:57
Vom Erkennen und Erfinden seiner selbst,es. Indeed, a number of these products, namely human insulin, human growth hormone and interferon alpha are now being marketed while others such as tissue plasminogen activator and hepatitis B vaccine are in advanced trials.作者: CLAMP 時間: 2025-3-22 01:40
Kinder brauchen (auch) die ?Power Rangers‘-Ser (Bu.).-Azgly.-LHRH; ‘Zoladex’ is a trade mark, the property of Imperial Chemical Industries PLC). However the therapeutic and commercial potential of polypeptide drugs will only be realised if these advances are accompanied by dosage form design leading to practical and effective formulations.作者: Axon895 時間: 2025-3-22 08:29
Intracellular Sorting of Proteins, (1) the eukaryotic secretory system; (2) the nucleus; (3) the mitochondria; (4) the chloroplasts; (5) the bacterial secretory system. The scope of this review does not allow in-depth treatment of all important aspects of protein sorting. For detailed reviews see Schekman (1985), Garoff (1985), Farquhar (1985) and Benson et al. (1985).作者: arrhythmic 時間: 2025-3-22 11:04
The Oral Bioavailability of Peptides and Related Drugs,ptide drugs (for review see Humphrey & Ringrose, 1986). The purpose of this review is to describe the various barriers to, and mechanisms of absorption of peptide drugs, as well as, to discuss the relationship between physio-chemical properties and absorption (see Table 1).作者: 含水層 時間: 2025-3-22 13:40
Der produktive Dialog als Verstehensmodellited for the absorption of drugs, especially those that are extensively metabolized in the gastrointestinal fluids and the gut wall or are subjected to an extensive first pass hepatic metabolism. The various regulatory peptides and proteins are good examples.作者: 含水層 時間: 2025-3-22 18:39 作者: 丑惡 時間: 2025-3-23 00:08 作者: Canyon 時間: 2025-3-23 03:21
Die Macht der Worte und der Medien been attributed to their potent pharmacological activity and their good biological tolerance. However, the disadvantages have been their broad pharmacological activity (which is often masked by a singular potent effect) and their relative short biological halflife (Table 1).作者: acrobat 時間: 2025-3-23 07:34 作者: maroon 時間: 2025-3-23 09:43 作者: Ingrained 時間: 2025-3-23 16:28 作者: WAG 時間: 2025-3-23 20:59
Intranasal Delivery of the Peptide, Salmon Calcitonin,he necessity of this daily injection is bothersome and inconvenient to patients. However, because the drug is a polypeptide subject to digestive degradation, it can not be given orally. Therefore, an alternate route of administration, such as intranasally, is attractive.作者: 即席演說 時間: 2025-3-24 02:12
Biotechnology and Protein Production,es. Indeed, a number of these products, namely human insulin, human growth hormone and interferon alpha are now being marketed while others such as tissue plasminogen activator and hepatitis B vaccine are in advanced trials.作者: BROOK 時間: 2025-3-24 02:20 作者: BUMP 時間: 2025-3-24 09:27
Medien ? Kultur ? Kommunikation (1) the eukaryotic secretory system; (2) the nucleus; (3) the mitochondria; (4) the chloroplasts; (5) the bacterial secretory system. The scope of this review does not allow in-depth treatment of all important aspects of protein sorting. For detailed reviews see Schekman (1985), Garoff (1985), Farquhar (1985) and Benson et al. (1985).作者: 傻瓜 時間: 2025-3-24 13:08 作者: 招募 時間: 2025-3-24 17:49
Book 1986sponse modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands alm作者: Ambiguous 時間: 2025-3-24 20:58
NATO Science Series A:http://image.papertrans.cn/d/image/265004.jpg作者: 致敬 時間: 2025-3-25 02:13
Kinder brauchen (auch) die ?Power Rangers‘tors are still at an early stage of exploration. The aim of receptor research is to purify and isolate receptor glycoproteins or glycolipids in order to further implement the knowledge of the physicochemical aspects involved in the interaction of opioids with their receptor.作者: Lumbar-Spine 時間: 2025-3-25 05:10 作者: 表臉 時間: 2025-3-25 08:30 作者: circuit 時間: 2025-3-25 14:38
Oral Delivery of Peptide Drugs,y have shown that peptides can be developed as highly effective therapeutic agents in a number of different areas. As with many other drugs, however, the therapeutic efficacy is often diminished by their inability to reach the site of action in adequate amounts, and the choice of administration route is therefore important.作者: visceral-fat 時間: 2025-3-25 16:11 作者: Bother 時間: 2025-3-25 20:32 作者: dithiolethione 時間: 2025-3-26 03:07
https://doi.org/10.1007/978-3-531-90555-6The rectal route has long been known as a specific absorption means for the delivery of lipophilic small molecules. In general rectal delivery exhibits several advantages as summarized in Table 1.作者: 牛馬之尿 時間: 2025-3-26 05:56
Peptide Analysis: Critical Technology for Evaluating Delivery Approaches,Peptides and proteins are emerging as an increasingly important chemical class of drugs as they become more readily available through improvements in recombinant DNA technology and approaches to their chemical synthesis.作者: Ardent 時間: 2025-3-26 11:43 作者: 使高興 時間: 2025-3-26 15:47
Enhanced Absorption and Lymphatic Transport of Macromolecules via the Rectal Route,The rectal route has long been known as a specific absorption means for the delivery of lipophilic small molecules. In general rectal delivery exhibits several advantages as summarized in Table 1.作者: 嚴重傷害 時間: 2025-3-26 17:41 作者: 多節(jié) 時間: 2025-3-26 23:58
978-1-4757-9962-0Springer Science+Business Media New York 1986作者: 內(nèi)部 時間: 2025-3-27 05:01
https://doi.org/10.1007/978-3-662-26168-2livery where the drug is intended to be absorbed from the gastrointestinal tract. Injectable systems (that include implants), suppositories and transdermal devices, have a more limited place in current therapy. Some of these administration systems can be employed directly for the delivery of peptide作者: 法律的瑕疵 時間: 2025-3-27 07:41 作者: QUAIL 時間: 2025-3-27 13:18
Kinder brauchen (auch) die ?Power Rangers‘rtainly, the development of peptide drugs will be a major area in drug research in the future. The application of peptides as clinically useful drugs is, however, seriously hampered due to substantial delivery problems. Peptides are readily degraded by enzymes in the gastrointestinal system and are 作者: miracle 時間: 2025-3-27 14:20 作者: wall-stress 時間: 2025-3-27 19:27 作者: 黃油沒有 時間: 2025-3-27 22:28 作者: 污穢 時間: 2025-3-28 05:11 作者: 鑲嵌細工 時間: 2025-3-28 07:26
Kinder brauchen (auch) die ?Power Rangers‘peptides as well as improvements in techniques leading to total chemical synthesis of lower molecular weight peptides such as ‘Zoladex’ (ICI 118630; D-Ser (Bu.).-Azgly.-LHRH; ‘Zoladex’ is a trade mark, the property of Imperial Chemical Industries PLC). However the therapeutic and commercial potentia作者: 難理解 時間: 2025-3-28 12:40
Medien ? Kultur ? Kommunikationic applications and to the design of peptide drugs. However a contributing factor to the therapeutic success of a drug is the availability of an oral formulation. For peptides and proteins, oral absorption and bioavailability is generally low (as shown in Table 2) relative to that expected of non-pe作者: 摘要記錄 時間: 2025-3-28 15:11 作者: 細微差別 時間: 2025-3-28 21:08 作者: 積習已深 時間: 2025-3-29 01:11 作者: 玉米棒子 時間: 2025-3-29 04:47
Der produktive Dialog als Verstehensmodelle surface available for drug absorption. Furthermore, the subepithelial layer is highly vascularized with large and fenestrated capillaries specially designed for rapid passage of fluid through the vascular wall (Mygind, 1978). Unlike absorption from the gastrointestinal tract the venous blood drain作者: exhilaration 時間: 2025-3-29 09:02
Vorverst?ndnis, Sinn und soziale Machthe success of this young upstart biotechnology industry. Although we were in agreement that biotechnology allows for a more rational approach to design of therapeutic agents, he argued that, “you cannot make it in the pharmaceutical industry simply on injectable hormones”. Whether or not the economi作者: Substance 時間: 2025-3-29 12:19
Der produktive Dialog als Verstehensmodelld a great deal of attention. For instance, the β-blocker propranolol (Hussain et al, 1979, 1980 a, b), the contraceptive agent progesterone (David et al, 1981; Hussain et al, 1981) and the anti-arrhythmic compound clofilium tosylate (Su et al, 1984) have been shown to be effectively absorbed via the作者: 會犯錯誤 時間: 2025-3-29 16:39 作者: relieve 時間: 2025-3-29 20:53
,Advanced Delivery Systems for Peptides and Proteins — Pharmaceutical Considerations,livery where the drug is intended to be absorbed from the gastrointestinal tract. Injectable systems (that include implants), suppositories and transdermal devices, have a more limited place in current therapy. Some of these administration systems can be employed directly for the delivery of peptide作者: 格子架 時間: 2025-3-30 02:48 作者: 沐浴 時間: 2025-3-30 04:43
Bioreversible Derivatization of Peptides,rtainly, the development of peptide drugs will be a major area in drug research in the future. The application of peptides as clinically useful drugs is, however, seriously hampered due to substantial delivery problems. Peptides are readily degraded by enzymes in the gastrointestinal system and are 作者: generic 時間: 2025-3-30 09:16 作者: PALMY 時間: 2025-3-30 13:45
Temporal and Pharmacokinetic Aspects in Delivery of Peptides and Proteins,ug. When an understanding of how an individual patient will absorb and eliminate a drug is coupled together with knowledge of the pharmacologic effects of a given amount of the drug, a particular dose can be selected that will result in clinical efficacy and minimal toxicity. Such considerations hav作者: ARY 時間: 2025-3-30 20:29
Enzymatic Barriers to Peptide and Protein Absorption and the Use of Penetration Enhancers to Modifythelia that are poorly absorptive, the presence of significant levels of enzymatic activity at various locations between the point of entry into the systemic circulation and the target site of a peptide or protein, the availability of multiple enzymes to degrade peptides and proteins at a given loca作者: 脫毛 時間: 2025-3-30 21:22
Intracellular Sorting of Proteins,orm specialized functions, such as oxidative phosphorylation within the mitochondria or ribosome assembly within the nucleolus. How do cells generate and maintain such an asymmetric, highly organized distribution of their proteins? Five major targets of protein transport have been studied in detail:作者: 裙帶關系 時間: 2025-3-31 04:40
Biodegradable Polymers for Sustained Release of Polypeptides,peptides as well as improvements in techniques leading to total chemical synthesis of lower molecular weight peptides such as ‘Zoladex’ (ICI 118630; D-Ser (Bu.).-Azgly.-LHRH; ‘Zoladex’ is a trade mark, the property of Imperial Chemical Industries PLC). However the therapeutic and commercial potentia作者: AROMA 時間: 2025-3-31 08:36
The Oral Bioavailability of Peptides and Related Drugs,ic applications and to the design of peptide drugs. However a contributing factor to the therapeutic success of a drug is the availability of an oral formulation. For peptides and proteins, oral absorption and bioavailability is generally low (as shown in Table 2) relative to that expected of non-pe作者: 苦惱 時間: 2025-3-31 12:08
Oral Delivery of Peptide Drugs,y have shown that peptides can be developed as highly effective therapeutic agents in a number of different areas. As with many other drugs, however, the therapeutic efficacy is often diminished by their inability to reach the site of action in adequate amounts, and the choice of administration rout作者: 壓碎 時間: 2025-3-31 17:08 作者: Paraplegia 時間: 2025-3-31 19:47 作者: 門閂 時間: 2025-4-1 01:35
Microspheres as a Potential Controlled Release Nasal Drug Delivery System,e surface available for drug absorption. Furthermore, the subepithelial layer is highly vascularized with large and fenestrated capillaries specially designed for rapid passage of fluid through the vascular wall (Mygind, 1978). Unlike absorption from the gastrointestinal tract the venous blood drain作者: Mystic 時間: 2025-4-1 04:20
