標題: Titlebook: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy; Emmanuel Donnadieu Book 2016 Springer International Publishing Switz [打印本頁] 作者: 櫥柜 時間: 2025-3-21 18:23
書目名稱Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy影響因子(影響力)
書目名稱Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy影響因子(影響力)學科排名
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書目名稱Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy網(wǎng)絡(luò)公開度學科排名
書目名稱Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy被引頻次
書目名稱Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy被引頻次學科排名
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書目名稱Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy年度引用學科排名
書目名稱Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy讀者反饋
書目名稱Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy讀者反饋學科排名
作者: 繼而發(fā)生 時間: 2025-3-21 20:35 作者: indemnify 時間: 2025-3-22 03:50 作者: 喚起 時間: 2025-3-22 07:44 作者: infantile 時間: 2025-3-22 08:43 作者: chiropractor 時間: 2025-3-22 16:20 作者: chiropractor 時間: 2025-3-22 19:49 作者: spinal-stenosis 時間: 2025-3-22 21:59
Vascular Normalization, T Cell Trafficking and Anti-tumor Immunity, at the tumor blood vessel interface and how therapies that are effective in normalizing the tumor vasculature such as anti-VEGF, tyrosine kinase inhibitors and vaccines targeting tumor blood vessel-associated antigens, among others, can re-establish T cell infiltration into an inflammatory tumor mi作者: tooth-decay 時間: 2025-3-23 01:57
Disruption of Anti-tumor T Cell Responses by Cancer-Associated Fibroblasts,espite their crucial role. Indeed, CAFs have been recently shown to be one of the more potent immune-suppressive cells of the tumor micro-environment. This chapter focuses on their roles on immune components of the tumor micro-environment, especially T cells. CAFs can impact T cells in two major way作者: constitutional 時間: 2025-3-23 09:35 作者: Collision 時間: 2025-3-23 13:14
Homing Improvement: Boosting T Cell Trafficking for Cancer Immunotherapy,mmatory migration of T cells is possible by modulating any number of components in the leukocyte migration machinery, from chemo-attractants, to integrins, to extracellular matrix adhesion ligands. Promising results suggest that the homing problem can indeed be overcome to remove a major barrier in 作者: 連鎖,連串 時間: 2025-3-23 15:36
Chemokines and T Cell Trafficking into Tumors: Strategies to Enhance Recruitment of T Cells into Tue transferred cytotoxic T cells are providing a possible means of overcoming such obstacles. Integration of such strategies in immunotherapy protocols may hopefully pave the way to a more successful clinical application of T cell immunotherapy.作者: surrogate 時間: 2025-3-23 18:55
2196-5501 that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy..978-3-319-82528-1978-3-319-42223-7Series ISSN 2196-5501 Series E-ISSN 2196-551X 作者: 打擊 時間: 2025-3-23 23:13 作者: cunning 時間: 2025-3-24 03:45
Book 2016velopment. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy..作者: 瑣事 時間: 2025-3-24 09:05 作者: 無能性 時間: 2025-3-24 14:09 作者: Benign 時間: 2025-3-24 15:50
2196-5501 niciples to T cell migration during efficient immune responsThis volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers.?However, despite recent suc作者: Feigned 時間: 2025-3-24 21:31
K. F. Leonhardt,R. v. Tiepermann,M. Dosstion, focusing on extra- and intracellular guidance cues gained primarily from intravital two photon imaging, and relate this with the efficient unfolding of adaptive immune responses. From this, we outline the challenges that T cells face entering and maneuvering inside non-lymphoid tissues including tumor sites.作者: Inscrutable 時間: 2025-3-25 00:25
Basic Rules of T Cell Migration,tion, focusing on extra- and intracellular guidance cues gained primarily from intravital two photon imaging, and relate this with the efficient unfolding of adaptive immune responses. From this, we outline the challenges that T cells face entering and maneuvering inside non-lymphoid tissues including tumor sites.作者: 鋸齒狀 時間: 2025-3-25 07:01
Book 2016py is starting to transform the treatment of advanced cancers.?However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume作者: linguistics 時間: 2025-3-25 10:43 作者: 贊成你 時間: 2025-3-25 13:30 作者: 序曲 時間: 2025-3-25 19:32 作者: 返老還童 時間: 2025-3-25 20:47
Emmanuel DonnadieuGives the latest research on specific defects in T cell trafficking, which hinder the success of cancer immunotherapy.Provides the basic priniciples to T cell migration during efficient immune respons作者: 革新 時間: 2025-3-26 00:09 作者: 充足 時間: 2025-3-26 07:08 作者: 類型 時間: 2025-3-26 10:40 作者: 土產(chǎn) 時間: 2025-3-26 13:22
M. D. Maines,M. J. Tomio,V. Janouseketed immunotherapies. Treatments, such as cancer vaccines, CAR T cells and immune checkpoint inhibitors, aim to activate and harness T cells against cancer. However, tumors induce pathological angiogenesis and, at the same time, condition the tumor blood vessels to form a tumor vascular network that作者: Costume 時間: 2025-3-26 20:46 作者: 強制令 時間: 2025-3-26 22:02
Duane R. Hospenthal,Thomas J. Walshies. It is now recognized that not only the density, but also the organization of tumor-infiltrating immune cells is critical for the shaping of the tumor microenvironment. In human cancers, several levels of structuration of lymphoid aggregates have been observed, including Tertiary Lymphoid Struct作者: Occipital-Lobe 時間: 2025-3-27 05:04
Russell E. Lewis,Nathan P. Wiederholds in leukemia using CAR-modified T cells and in metastatic melanoma using tumor-infiltrating lymphocytes have provided impetus to expand adoptive cellular immunotherapy into treatment of solid tumors. In this setting, adoptively-transferred T cells face a hostile tumor environment that suppresses th作者: 青少年 時間: 2025-3-27 06:43
Luis Ostrosky-Zeichner,Jack D. Sobellogical conditions. Yet they are also expressed in tumors and their metastases. There, they mediate a variety of tumor-specific functions, including the recruitment of different immune cell populations to the tumor site. These cells may have a pro- or anti-tumoral function. Yet the cells mediating t作者: 社團 時間: 2025-3-27 10:48 作者: 吹氣 時間: 2025-3-27 17:29
Basic Rules of T Cell Migration,enhancing antitumor responses, have kindled a huge interest in cancer immunotherapy. In fact, adoptive cell therapy (ACT) of tumor-recognizing T cells has led to complete recession of tumors in a subset of melanoma patients. Yet, the molecular mechanisms that guide T cells to infiltrate tumor tissue作者: 生命層 時間: 2025-3-27 18:01
Regulation of Anti-tumor T Cell Migration and Function: Contribution of Real-Time Imaging,nt a major cell type in the antitumor immune response as they can specifically recognize and target transformed cells. Immunotherapies based on enhancing antitumor T cell functions are being actively developed with many clinical trials underway. Yet, the definition of basic migratory patterns of lym作者: 先行 時間: 2025-3-27 22:54
Vascular Normalization, T Cell Trafficking and Anti-tumor Immunity,eted immunotherapies. Treatments, such as cancer vaccines, CAR T cells and immune checkpoint inhibitors, aim to activate and harness T cells against cancer. However, tumors induce pathological angiogenesis and, at the same time, condition the tumor blood vessels to form a tumor vascular network that作者: 慌張 時間: 2025-3-28 02:20
Disruption of Anti-tumor T Cell Responses by Cancer-Associated Fibroblasts,t the only component of a tumor and the non-cancer cell part of the tumor has been termed stroma. The tumor stroma comprises cells of at least three different origins: endothelial, mesenchymal and hematopoietic, thereby forming a complex microenvironment. Among these three elements, immune cells hav作者: Fraudulent 時間: 2025-3-28 07:00
Cancer-Associated Tertiary Lymphoid Structures, from Basic Knowledge Toward Therapeutic Target in Cies. It is now recognized that not only the density, but also the organization of tumor-infiltrating immune cells is critical for the shaping of the tumor microenvironment. In human cancers, several levels of structuration of lymphoid aggregates have been observed, including Tertiary Lymphoid Struct作者: CUMB 時間: 2025-3-28 11:42
Homing Improvement: Boosting T Cell Trafficking for Cancer Immunotherapy,s in leukemia using CAR-modified T cells and in metastatic melanoma using tumor-infiltrating lymphocytes have provided impetus to expand adoptive cellular immunotherapy into treatment of solid tumors. In this setting, adoptively-transferred T cells face a hostile tumor environment that suppresses th作者: Commentary 時間: 2025-3-28 17:57 作者: PON 時間: 2025-3-28 21:49
Strategies to Enhance Migration and Persistence of Chimeric Antigen Receptor (CAR)-T Cells into TumThis result has been obtained through the improvement of the methodologies used to expand ex vivo antigen-specific T cells, and through technology advancements in T-cell engineering aimed at transferring into these cells chimeric antigen receptors (CAR) or αβTCRs chains. High enthusiasm is especiall
