標題: Titlebook: Death Receptors in Cancer Therapy; Wafik S. El-Deiry Book 2005 Humana Press 2005 TNF.apoptosis.carcinoma.cell.cell death.gene therapy.inte [打印本頁] 作者: 轉(zhuǎn)變 時間: 2025-3-21 17:58
書目名稱Death Receptors in Cancer Therapy影響因子(影響力)
書目名稱Death Receptors in Cancer Therapy影響因子(影響力)學科排名
書目名稱Death Receptors in Cancer Therapy網(wǎng)絡公開度
書目名稱Death Receptors in Cancer Therapy網(wǎng)絡公開度學科排名
書目名稱Death Receptors in Cancer Therapy被引頻次
書目名稱Death Receptors in Cancer Therapy被引頻次學科排名
書目名稱Death Receptors in Cancer Therapy年度引用
書目名稱Death Receptors in Cancer Therapy年度引用學科排名
書目名稱Death Receptors in Cancer Therapy讀者反饋
書目名稱Death Receptors in Cancer Therapy讀者反饋學科排名
作者: Hot-Flash 時間: 2025-3-22 00:05
https://doi.org/10.1007/978-3-030-22094-5 None of the other members of the TNFR family identified to date contain recognizable intracellular domains, and instead present binding sites for interactions with TNF receptor-associated factors (TRAFs) and other adaptor proteins.作者: Ointment 時間: 2025-3-22 01:00 作者: FAR 時間: 2025-3-22 07:04
Mammalian Cell Death Pathways,immune surveillance/suppression of cancer. Caspase activation is highly regulated and defects at virtually all levels of death regulation are observed in cancer. This chapter focuses on the cell biology, biochemistry, and genetics of programmed cell death.作者: CLAY 時間: 2025-3-22 11:41
Death Signaling and Therapeutic Applications of TRAIL,ecules, ligand-type cytokine molecules including the tumor necrosis factor (TNF) family members have been best characterized. The TNF family members most extensively characterized for death signaling and structure include TNF-α, Fas ligand (FasL), and TNF-related apoptosis-inducing ligand (TRAIL).作者: 朋黨派系 時間: 2025-3-22 13:41 作者: 朋黨派系 時間: 2025-3-22 18:52
Regulation of Death Receptors by Synthetic Retinoids,s such as acne and psoriasis, and in the prevention or treatment of certain types of cancer, such as the treatment of acute promyelocytic leukemia (APL) and cutaneous T-cell lymphoma, reversal of premalignant lesions, and inhibition of the development of second primary tumors (.,.).作者: voluble 時間: 2025-3-23 00:15
Proapoptotic Gene Silencing Via Methylation in Human Tumors,eath, disassembly of various cellular components, and eventual engulfment of the resulting cellular debris (.,.). Inappropriate apoptosis has been associated with a variety of pathological conditions, such as neurodegenerative disorders, autoimmune phenomena, mitochondrial disorders, ischemic damage and cancer (.,.).作者: obstruct 時間: 2025-3-23 02:14
Book 2005ors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.作者: 投票 時間: 2025-3-23 08:15
Book 2005g agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death recept作者: 白楊魚 時間: 2025-3-23 09:48 作者: condone 時間: 2025-3-23 16:50
Ceramide, Ceramidase, and FasL Gene Therapy in Prostate Cancer,or bioactive lipids (.–.). Thus, regulation of sphingolipid metabolism appears involved in regulation of cell growth, differentiation, senescence, and programmed cell death, and possibly, as proposed herein, favoring growth of a subset of prostate cancers.作者: 無畏 時間: 2025-3-23 18:00
Spyridon Karageorgos,Hamid Bassiriimmune surveillance/suppression of cancer. Caspase activation is highly regulated and defects at virtually all levels of death regulation are observed in cancer. This chapter focuses on the cell biology, biochemistry, and genetics of programmed cell death.作者: 放逐某人 時間: 2025-3-23 23:52 作者: 泥沼 時間: 2025-3-24 04:58
Laurence Arbibe,Philippe Sansonetting apoptosis-related proteins contribute to either development or progression of human cancers. In this chapter, we present an overview of the death receptor pathway and its dysregulation in cancers. We then review the current knowledge of death receptor mutations that have been detected in humans.作者: Disk199 時間: 2025-3-24 10:25 作者: 悠然 時間: 2025-3-24 14:27 作者: 存心 時間: 2025-3-24 15:51
2196-9906 olecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance 作者: erythema 時間: 2025-3-24 22:35 作者: FLAX 時間: 2025-3-25 03:03
https://doi.org/10.1007/978-1-4613-1137-9or bioactive lipids (.–.). Thus, regulation of sphingolipid metabolism appears involved in regulation of cell growth, differentiation, senescence, and programmed cell death, and possibly, as proposed herein, favoring growth of a subset of prostate cancers.作者: gout109 時間: 2025-3-25 06:26 作者: archetype 時間: 2025-3-25 07:54
Death Receptor Signaling in Embryonic Ectodermal Development,n the absence or presence of sweat gland function—hidrotic ectodermal dysplasia (or Clouston syndrome) and hypohidrotic ectodermal dysplasias (HEDs). Recent studies suggest an important role of signaling via the tumor necrosis factor receptor (TNFR) family in the pathogenesis of hypohidrotic ectoder作者: Misnomer 時間: 2025-3-25 15:35
Adaptor Proteins in Death Receptor Signaling,he function of each adaptor, we hope to construct a blueprint of the various signaling channels triggered by death receptors, providing a foundation for further scientific investigations and practical therapeutic designs.作者: occult 時間: 2025-3-25 19:54 作者: FLUSH 時間: 2025-3-25 22:21 作者: 細菌等 時間: 2025-3-26 02:40 作者: ERUPT 時間: 2025-3-26 07:52 作者: curettage 時間: 2025-3-26 10:21
TRAIL in Cancer Therapy,ignaling by mechanisms that remain poorly understood. Interestingly, a number of recent reports suggest that a key to the success of TRAIL in cancer therapy is to use it in conjunction with chemo- or radiotherapy. Such a concept of combination therapy is gaining ground in eliminating tumors that are作者: 記憶 時間: 2025-3-26 13:47
Expression and Regulation of Death Receptors in Multiple Myeloma and Prostate Carcinoma,on level following genotoxic stress was prevented or attenuated in prostate cancer cells stably expressing a dominant-negative p53 mutant. Of the TNF family members, one that has received much attention recently is Apo2L/TRAIL (Apo2 ligand or TNF-related apoptosis-inducing ligand). Apo2L/TRAIL is un作者: Jingoism 時間: 2025-3-26 18:41 作者: fatty-streak 時間: 2025-3-26 23:58
Sensitizing Tumor Cells by Targeting Death Receptor Signaling Inhibitors,d resistance, and strategies to enhance sensitivity or overcome resistance have been devised. In this chapter the role, function, and regulation of the death receptor signaling pathway inhibitors, how they can be targeted therapeutically, and the implications for future cancer therapies will be disc作者: NEX 時間: 2025-3-27 04:25 作者: 衰老 時間: 2025-3-27 06:06
Randy Q. Cron,Edward M. Behrensn the absence or presence of sweat gland function—hidrotic ectodermal dysplasia (or Clouston syndrome) and hypohidrotic ectodermal dysplasias (HEDs). Recent studies suggest an important role of signaling via the tumor necrosis factor receptor (TNFR) family in the pathogenesis of hypohidrotic ectoder作者: encomiast 時間: 2025-3-27 09:55 作者: CHAR 時間: 2025-3-27 14:27
https://doi.org/10.1007/978-1-59259-129-9lysis has revealed a core apoptotic program in . comprised of three genes: CED-3, CED-4, and CED-9, with the first two promoting apoptosis and the latter inhibiting it. Epistatic analysis has identified CED-3 as the most downstream component of this program, suggesting that the functions of CED-4 an作者: Nerve-Block 時間: 2025-3-27 19:40
Laurence Arbibe,Philippe Sansonettianoma lines by culture in TRAIL was also associated with decreased expression of TRAIL-R2 protein, but TRAIL-R2 mRNA levels were similar to those in parental high-TRAIL-R2 expressing cells. The latter model was used to explore post-transcriptional regulation of TRAIL-R2. Expression from a luciferase作者: Lamina 時間: 2025-3-27 23:28
Michael S. Rolph,Stefan H. E. Kaufmannrnal symmetry. The consensus DNA sequence for p53 binding is 5′-PuPuPuC(A/T-A/T)GPyPyPy- N(0-13)-PuPuPuC(A/T-A/T)GPyPyPy-3′, with the third C and seventh G being highly conserved in the 10-base-pair half-sites (.). Identification of transcriptional targets of p53 has been critical in dissecting path作者: cavity 時間: 2025-3-28 03:54 作者: 基因組 時間: 2025-3-28 07:35
Arne von Bonin,Solveig H. Moré,Minka Breloerignaling by mechanisms that remain poorly understood. Interestingly, a number of recent reports suggest that a key to the success of TRAIL in cancer therapy is to use it in conjunction with chemo- or radiotherapy. Such a concept of combination therapy is gaining ground in eliminating tumors that are作者: 燒瓶 時間: 2025-3-28 12:22 作者: concise 時間: 2025-3-28 15:46 作者: 四海為家的人 時間: 2025-3-28 22:47
L. M. L. Tuyt,W. H. A. Dokter,E. Vellengad resistance, and strategies to enhance sensitivity or overcome resistance have been devised. In this chapter the role, function, and regulation of the death receptor signaling pathway inhibitors, how they can be targeted therapeutically, and the implications for future cancer therapies will be disc作者: mettlesome 時間: 2025-3-29 00:22 作者: Institution 時間: 2025-3-29 03:15
Resistance to Apoptosis in Cancer Therapy,se. Parallel efforts have defined the evolutionarily conserved components of the apoptotic pathway, inspiring efforts to characterize the functional status of these components in human tumor cells. Although core pathway defects have been documented, the apoptotic pathway appears to be intact in most作者: 態(tài)度暖昧 時間: 2025-3-29 09:09
Structures of TNF Receptors and Their Interactions With Ligands, apoptosis, modulation of the immune system, and regulation of developmental pathways in some tissue types. Some TNFRs positively regulate cell growth, whereas others initiate apoptotic pathways upon stimulation by ligand (.). These contradictory biological activities are determined to some extent b作者: ovation 時間: 2025-3-29 14:12
Death Receptor Signaling in Embryonic Ectodermal Development,o derivatives of ectoderm (e.g., skin, nails, sweat glands, or teeth) (.). More than 150 different types of EDs have been identified, and the combined incidence of these disorders may be as high as 7 per 10,000 births. However, a large number of cases go undetected due to the relatively mild phenoty作者: Cocker 時間: 2025-3-29 18:31
Adaptor Proteins in Death Receptor Signaling,ch for the past several years. The major advances arising from these studies have been the characterization of critical signal-transducing adaptor molecules and the delineation of parallel but opposing signaling pathways, some inducing apoptosis and others promoting cell survival. An imbalance in fa作者: 逗它小傻瓜 時間: 2025-3-29 20:56 作者: antenna 時間: 2025-3-29 23:55 作者: Overdose 時間: 2025-3-30 05:35 作者: FRAX-tool 時間: 2025-3-30 10:11
Regulation of Death Receptors,ation. The expression of the members of the death receptor family is tightly regulated and varies among tissues. Dysregulation of death receptor expression is implicated in the pathogenesis of various diseases, including cancer, autoimmune disorders, neurodegenerative diseases, and infections. In th作者: creatine-kinase 時間: 2025-3-30 13:53
Regulation of Trail Receptor Expression in Human Melanoma,s a major determinant of the sensitivity of melanoma cell lines to TRAIL-induced apoptosis. Transcriptional events regulating TRAIL death receptor expression have been the focus of much study, but our investigations point to a more important role for posttranscriptional events in regulation of TRAIL作者: Fretful 時間: 2025-3-30 18:44
Regulation of Death Receptors by Synthetic Retinoids,erentiation, and apoptosis of many cell types (.). Thus, they play important roles in regulating, among other things, embryonic development, hematopoiesis, bone formation, glucose and lipid metabolism, and carcinogenesis (.). Currently, retinoids are used clinically in the treatment of skin disorder作者: Palatial 時間: 2025-3-30 22:36 作者: cancer 時間: 2025-3-31 01:22
Proapoptotic Gene Silencing Via Methylation in Human Tumors,de. This process plays a crucial role in the normal life cycle of organisms, facilitating embryonic development, metamorphosis, cellular specialization; maintaining homeostasis (.,.). Apoptosis is characterized by a complex set of tightly controlled biochemical and molecular events leading to cell d作者: 浪蕩子 時間: 2025-3-31 05:50 作者: 防銹 時間: 2025-3-31 10:17 作者: innovation 時間: 2025-3-31 13:57 作者: 牽連 時間: 2025-3-31 20:41 作者: Emg827 時間: 2025-4-1 00:50
Sensitizing Tumor Cells by Targeting Death Receptor Signaling Inhibitors,ctive area of research in the development of novel anticancer therapies. Systemic delivery of FasL causes hepatotoxicity, limiting its use to local administration (.). In contrast, preclinical studies with TRAIL show that systemic delivery of the soluble form is well tolerated in nonhuman primates (作者: 小蟲 時間: 2025-4-1 05:32 作者: INCUR 時間: 2025-4-1 07:47
https://doi.org/10.1385/159259851XTNF; apoptosis; carcinoma; cell; cell death; gene therapy; interferon; melanoma; prostate cancer; tumor作者: 魔鬼在游行 時間: 2025-4-1 13:45 作者: Esophagitis 時間: 2025-4-1 16:38 作者: exophthalmos 時間: 2025-4-1 20:24 作者: indifferent 時間: 2025-4-2 01:11
