標(biāo)題: Titlebook: Data Mining Techniques for the Life Sciences; Oliviero Carugo,Frank Eisenhaber Book 2022Latest edition The Editor(s) (if applicable) and T [打印本頁] 作者: 相反 時(shí)間: 2025-3-21 18:27
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書目名稱Data Mining Techniques for the Life Sciences網(wǎng)絡(luò)公開度學(xué)科排名
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書目名稱Data Mining Techniques for the Life Sciences被引頻次學(xué)科排名
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書目名稱Data Mining Techniques for the Life Sciences年度引用學(xué)科排名
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書目名稱Data Mining Techniques for the Life Sciences讀者反饋學(xué)科排名
作者: LIMN 時(shí)間: 2025-3-21 20:46
Oliviero Carugo,Frank EisenhaberIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts作者: 幻想 時(shí)間: 2025-3-22 03:36 作者: NEG 時(shí)間: 2025-3-22 05:00 作者: 藥物 時(shí)間: 2025-3-22 09:08
978-1-0716-2097-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines作者: EXULT 時(shí)間: 2025-3-22 14:49 作者: EXULT 時(shí)間: 2025-3-22 20:27
Collaborative Networked Organizationsture. These data can then be used to perform network analysis, to assign putative roles to uncharacterized proteins and to investigate their involvement in cellular pathways..This chapter gives a brief overview of publicly available molecular interaction databases and focuses on the members of the I作者: arrogant 時(shí)間: 2025-3-22 22:07
Some American Research Concerns on VO biomacromolecular structures is the Protein Data Bank (PDB). It is managed by wwPDB, a consortium of five partner institutions: the Protein Data Bank in Europe (PDBe), the Research Collaboratory for Structural Bioinformatics (RCSB), the Protein Data Bank Japan (PDBj), the BioMagResBank (BMRB), and 作者: 男學(xué)院 時(shí)間: 2025-3-23 05:19
Sanaz Nikghadam-Hojjati,José Barata. Intrinsically disordered proteins are ubiquitous proteins that fulfill essential biological functions while lacking a stable 3D structure. Their conformational heterogeneity is encoded by the amino acid sequence, thereby allowing intrinsically disordered proteins or regions to be recognized based 作者: floodgate 時(shí)間: 2025-3-23 05:35 作者: 審問 時(shí)間: 2025-3-23 12:50
Christian Zinke-Wehlmann,Julia Friedrichdiction upon variations, we now realize that all the approaches are poorly performing when tested on specific cases and that there is large space for improvement. Why this is so? Is it wrong the underlying assumption that experimental protein thermodynamics in solution reflects the thermodynamics of作者: deficiency 時(shí)間: 2025-3-23 15:52 作者: Lignans 時(shí)間: 2025-3-23 18:34
W. Mulder,P. H. H. Rongen,G. R. Meijering aggregation or order-disorder conformational transitions. Surprisingly, bioinformatic platforms often disregard the protein context in their modeling. In a recent work, we proposed that modeling how pH affects protein net charge and hydrophobicity might allow us to forecast pH-dependent aggregat作者: Psa617 時(shí)間: 2025-3-23 23:27
Felipe Bittencourt,Ricardo J. Rabelo results similar to those produced by principal components analysis of a molecular dynamics simulation, but with only a fraction of the computational effort. Here, we provide a brief overview of the theory and describe three methods for carrying out NMA, including the use of one of the on-line servi作者: Nutrient 時(shí)間: 2025-3-24 03:48 作者: 改革運(yùn)動(dòng) 時(shí)間: 2025-3-24 06:41
Bart Bogaard,Baris Ozkan,Sybren de Kinderenal organization is in action for gene expression, tissue and organ architectures, and ecological systems..The still more common approach to such state of affairs is to think that causally relevant events originate from the lower level in the form of perturbations, that climb up the hierarchy reachin作者: 記憶 時(shí)間: 2025-3-24 14:23
https://doi.org/10.1007/978-3-031-42622-3ies in biological macromolecules. In this chapter, the most recent studies and applications of B-factors in protein engineering and structural biology are briefly summarized. Particular emphasis is given to the limitations in using B-factors, in order to prevent inappropriate applications. It is eve作者: attenuate 時(shí)間: 2025-3-24 15:05 作者: myelography 時(shí)間: 2025-3-24 22:06 作者: Default 時(shí)間: 2025-3-25 01:47 作者: 罐里有戒指 時(shí)間: 2025-3-25 05:49 作者: 多產(chǎn)魚 時(shí)間: 2025-3-25 09:24 作者: 知識(shí) 時(shí)間: 2025-3-25 13:07 作者: 抒情短詩 時(shí)間: 2025-3-25 19:45
Pre- and Post-publication Verification for Reproducible Data Mining in Macromolecular Crystallographh foundations that reproducible data mining is based. Data rates are expanding considerably be they at synchrotrons, the X-ray free electron lasers (XFELs), electron cryomicroscopes (cryoEM), or at the neutron facilities. The work of a person as a referee or user with a narrative and its underpinnin作者: 使成波狀 時(shí)間: 2025-3-25 20:30 作者: 遺傳 時(shí)間: 2025-3-26 01:52
Optimizing the Parametrization of Homologue Classification in the Pan-Genome Computation for a Bactetity (60%) and coverage (50–60%) in the pairwise alignment) for the orthologous clustering of gene sequences. We find that the sequence identity threshold influences the number of gene families ~3 times stronger than the sequence coverage threshold.作者: 舊病復(fù)發(fā) 時(shí)間: 2025-3-26 06:46 作者: 誘使 時(shí)間: 2025-3-26 11:31 作者: 凝結(jié)劑 時(shí)間: 2025-3-26 13:34 作者: CRAMP 時(shí)間: 2025-3-26 19:24 作者: Afflict 時(shí)間: 2025-3-27 00:00 作者: 或者發(fā)神韻 時(shí)間: 2025-3-27 02:51
Hamideh Afsarmanesh,Luis M. Camarinha-Matosh foundations that reproducible data mining is based. Data rates are expanding considerably be they at synchrotrons, the X-ray free electron lasers (XFELs), electron cryomicroscopes (cryoEM), or at the neutron facilities. The work of a person as a referee or user with a narrative and its underpinnin作者: idiopathic 時(shí)間: 2025-3-27 07:40
Bart Bogaard,Baris Ozkan,Sybren de Kinderenzation. These measures, while keeping their original physical meaning, must not impose theoretical premises not verifiable in biological frameworks. We will show here how relatively simple and largely hypothesis-free multidimensional statistics tools can satisfactorily meet these criteria.作者: transplantation 時(shí)間: 2025-3-27 12:15
Bart Bogaard,Baris Ozkan,Sybren de Kinderentity (60%) and coverage (50–60%) in the pairwise alignment) for the orthologous clustering of gene sequences. We find that the sequence identity threshold influences the number of gene families ~3 times stronger than the sequence coverage threshold.作者: medieval 時(shí)間: 2025-3-27 14:50
https://doi.org/10.1007/978-3-031-42622-3selectivity. The mechanism-agnostic and cost-effective computational methods are widely applicable to various cancer types, which are amenable to drug testing, as the computational methods take as input only the phenotypic measurements of a subset of drug combinations, without requiring target infor作者: febrile 時(shí)間: 2025-3-27 21:00 作者: 象形文字 時(shí)間: 2025-3-28 01:04 作者: 親屬 時(shí)間: 2025-3-28 02:12 作者: 角斗士 時(shí)間: 2025-3-28 10:08 作者: BRIEF 時(shí)間: 2025-3-28 14:15 作者: textile 時(shí)間: 2025-3-28 15:15
Profiles of Natural and Designed Protein-Like Sequences Effectively Bridge Protein Sequence Gaps: Im protein families. Powerful profile-based sequence search methods rely on a sequence space continuum to identify non-trivial relationships through homology detection. The computational design of protein-like sequences that serve as “artificial linkers” is useful in identifying relationships between 作者: scotoma 時(shí)間: 2025-3-28 20:05
Turning Failures into Applications: The Problem of Protein ΔΔ, Predictiondiction upon variations, we now realize that all the approaches are poorly performing when tested on specific cases and that there is large space for improvement. Why this is so? Is it wrong the underlying assumption that experimental protein thermodynamics in solution reflects the thermodynamics of作者: Psa617 時(shí)間: 2025-3-28 23:59 作者: 描繪 時(shí)間: 2025-3-29 05:56 作者: 催眠 時(shí)間: 2025-3-29 08:48
Extracting the Dynamic Motion of Proteins Using Normal Mode Analysis results similar to those produced by principal components analysis of a molecular dynamics simulation, but with only a fraction of the computational effort. Here, we provide a brief overview of the theory and describe three methods for carrying out NMA, including the use of one of the on-line servi作者: palliate 時(shí)間: 2025-3-29 14:05 作者: 震驚 時(shí)間: 2025-3-29 15:38 作者: insert 時(shí)間: 2025-3-29 22:58
Uses and Abuses of the Atomic Displacement Parameters in Structural Biologyies in biological macromolecules. In this chapter, the most recent studies and applications of B-factors in protein engineering and structural biology are briefly summarized. Particular emphasis is given to the limitations in using B-factors, in order to prevent inappropriate applications. It is eve作者: 毛細(xì)血管 時(shí)間: 2025-3-30 00:42
Optimizing the Parametrization of Homologue Classification in the Pan-Genome Computation for a Bactel sequence diversity within organism populations, strain collections, clades, etc. A single genome is no longer sufficient to describe bacteria of interest, but instead, the genomic repertoire of all existing strains is the key to the metabolic, evolutionary, or pathogenic potential of a species. Th作者: Gourmet 時(shí)間: 2025-3-30 05:15
Computational Pipeline for Rational Drug Combination Screening in Patient-Derived Cellstherapies as next-line regimens. However, due to a massive number of possible drug combinations to test, there is a need for systematic and rational approaches to finding safe and effective drug combinations for each individual patient. This protocol describes an ecosystem of computational methods t作者: 鋼盔 時(shí)間: 2025-3-30 12:17
Deep Mining from Omics Datadely available to researchers. This has afforded clinicians, bioinformaticians, statisticians, and data scientists the opportunity to apply their innovations in feature mining and predictive modeling to a rich data resource to develop a wide range of generalizable prediction models. What has become 作者: 媽媽不開心 時(shí)間: 2025-3-30 13:16 作者: antidote 時(shí)間: 2025-3-30 18:49
Christian Zinke-Wehlmann,Julia Friedrichw how to cope with the problem of understanding which protein positions may be of interest for biotechnological and biomedical purposes. By applying a consensus procedure, we indicate possible strategies for the result interpretation.作者: craving 時(shí)間: 2025-3-30 20:59 作者: Tidious 時(shí)間: 2025-3-31 03:43
W. Mulder,P. H. H. Rongen,G. R. Meijerst dedicated software to predict pH-dependent aggregation, and DispHred is the first pH-dependent predictor of protein disorder. Here we dissect the features of these two software applications to train and assist scientists in studying pH-dependent conformational changes in IDPs.作者: Blood-Clot 時(shí)間: 2025-3-31 08:23
IMEx Databases: Displaying Molecular Interactions into a Single, Standards-Compliant Datasette molecular interaction data to the highest caliber, following a detailed curation model and supplying rich metadata by employing common curation rules and harmonized standards. The IMEx Consortium provides comprehensively annotated molecular interaction data integrated into a single, non-redundant, open access dataset.
