標(biāo)題: Titlebook: Data Mining Techniques for the Life Sciences; Oliviero Carugo,Frank Eisenhaber Book 2016Latest edition Springer Science+Business Media New [打印本頁(yè)] 作者: LEVEE 時(shí)間: 2025-3-21 19:32
書目名稱Data Mining Techniques for the Life Sciences影響因子(影響力)
書目名稱Data Mining Techniques for the Life Sciences影響因子(影響力)學(xué)科排名
書目名稱Data Mining Techniques for the Life Sciences網(wǎng)絡(luò)公開(kāi)度
書目名稱Data Mining Techniques for the Life Sciences網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書目名稱Data Mining Techniques for the Life Sciences被引頻次
書目名稱Data Mining Techniques for the Life Sciences被引頻次學(xué)科排名
書目名稱Data Mining Techniques for the Life Sciences年度引用
書目名稱Data Mining Techniques for the Life Sciences年度引用學(xué)科排名
書目名稱Data Mining Techniques for the Life Sciences讀者反饋
書目名稱Data Mining Techniques for the Life Sciences讀者反饋學(xué)科排名
作者: exercise 時(shí)間: 2025-3-21 23:03
Protein Structure Databasese various atlases that describe each experimentally determined protein structure and provide useful links, analyses, and schematic diagrams relating to its 3D structure and biological function. Also of great interest are the databases that classify 3D structures by their folds as these can reveal ev作者: ungainly 時(shí)間: 2025-3-22 04:26 作者: geriatrician 時(shí)間: 2025-3-22 07:25
Applications of Protein Thermodynamic Database for Understanding Protein Mutant Stability and Designlly, protein stability is measured with circular dichroism, differential scanning calorimetry, and fluorescence spectroscopy using thermal and denaturant denaturation methods. These experimental data have been accumulated in the form of a database, ProTherm, thermodynamic database for proteins and m作者: follicular-unit 時(shí)間: 2025-3-22 12:16
Classification and Exploration of 3D Protein Domain Interactions Using Kbdocknction and evolutionary relationships. Additionally, structural knowledge of existing domain–domain interactions can provide a useful way to find structural templates with which to model the 3D structures of unsolved protein complexes. Here we present a straightforward guide to using the “Kbdock” pr作者: 舊石器時(shí)代 時(shí)間: 2025-3-22 13:22
Data Mining of Macromolecular Structuresimization in drug development. Applying data mining techniques on these experimentally determined structures requires a highly uniform, standardized structural data source. The Protein Data Bank (PDB) has evolved over the years toward becoming the standard resource for macromolecular structures. How作者: 舊石器時(shí)代 時(shí)間: 2025-3-22 19:05
Criteria to Extract High-Quality Protein Data Bank Subsets for Structure Users the subsets are non-redundant and of high quality. The first problem can be solved relatively easily at the sequence level or at the structural level. The second, on the contrary, needs special attention. It is not sufficient, in fact, to consider the crystallographic resolution and other feature m作者: 偏見(jiàn) 時(shí)間: 2025-3-22 22:48 作者: 自愛(ài) 時(shí)間: 2025-3-23 01:27 作者: Microaneurysm 時(shí)間: 2025-3-23 05:55 作者: antidepressant 時(shí)間: 2025-3-23 13:46
Systematic Exploration of an Efficient Amino Acid Substitution Matrix: MIQSd function. In this study, we improve amino acid substitution matrices to identify distantly related proteins. We systematically sampled and benchmarked substitution matrices generated from the principal component analysis (PCA) subspace based on a set of typical existing matrices. Based on the benc作者: preeclampsia 時(shí)間: 2025-3-23 15:56
Promises and Pitfalls of High-Throughput Biological Assaystrategies and guidelines that researchers should follow when undertaking such studies. We discuss common errors in experimental design and data analysis that lead to irreproducible and non-replicable research and provide some guidelines to avoid these common mistakes so that researchers may have con作者: Acquired 時(shí)間: 2025-3-23 21:51 作者: absorbed 時(shí)間: 2025-3-24 01:37
Predicting Conformational Disordersordered proteins are ubiquitous proteins that fulfill essential biological functions while lacking a stable 3D structure. Their conformational heterogeneity is encoded at the amino acid sequence level, thereby allowing intrinsically disordered proteins or regions to be recognized based on their seq作者: 表示向前 時(shí)間: 2025-3-24 03:32
Classification of Protein Kinases Influenced by Conservation of Substrate Binding Residues kinases are generally classified into different subfamilies based on their sequence similarity with members of known subfamilies of kinases. A functional association is then defined to the kinase based on the subfamily to which it has been characterized. However, one of the key factors that give id作者: Misgiving 時(shí)間: 2025-3-24 06:55
Spectral–Statistical Approach for Revealing Latent Regular Structures in DNA Sequenceis in the HeteroGenome database which collects the sequences similar to approximate tandem repeats in the genomes of model organisms are adduced. In consequence of further developing of the spectral–statistical approach, the techniques for recognizing latent profile periodicity are considered. These作者: harbinger 時(shí)間: 2025-3-24 13:11 作者: defendant 時(shí)間: 2025-3-24 17:51
Data Mining of Macromolecular Structuresptimization methods have on structural models and how validation tools can be used to make informed choices. We also discuss specific advantages of using the PDB_REDO databank as a resource for structural data. Finally, we will provide guidelines on how to select the most suitable protein structure 作者: 熔巖 時(shí)間: 2025-3-24 20:44
Criteria to Extract High-Quality Protein Data Bank Subsets for Structure Userse incessant growth of the Protein Data Bank and especially of the number of high-resolution structures is allowing the use of more stringent selection criteria, with a consequent improvement of the quality of the subsets of the Protein Data Bank.作者: PALSY 時(shí)間: 2025-3-24 23:51
Promises and Pitfalls of High-Throughput Biological Assaysta, and methods to correct for it are presented, as well as approaches to detect and correct for experimental biases and batch effects, which often plague high-throughput assays. We highlight the importance of sharing data and analysis code to facilitate reproducibility and present tools and softwar作者: 鴿子 時(shí)間: 2025-3-25 04:22
Classification of Protein Kinases Influenced by Conservation of Substrate Binding Residuesand render a better understanding of their functional role. In this analysis we emphasize on the possibility of using putative substrate binding information in the classification of a given kinase into a particular subfamily.作者: jovial 時(shí)間: 2025-3-25 09:03 作者: Culpable 時(shí)間: 2025-3-25 13:49
Collaborative Innovation Networksg thermodynamics, structure, and function of proteins. We describe the recent progress on the development of methods for understanding/predicting protein stability, such as (1) general trends on mutational effects on stability, (2) relationship between the stability of protein mutants and amino acid作者: 不可思議 時(shí)間: 2025-3-25 18:30
Collaborative Innovation Networksptimization methods have on structural models and how validation tools can be used to make informed choices. We also discuss specific advantages of using the PDB_REDO databank as a resource for structural data. Finally, we will provide guidelines on how to select the most suitable protein structure 作者: 充足 時(shí)間: 2025-3-25 22:10
Carlo Alberto Amadei,Monica Baraldi Borgidae incessant growth of the Protein Data Bank and especially of the number of high-resolution structures is allowing the use of more stringent selection criteria, with a consequent improvement of the quality of the subsets of the Protein Data Bank.作者: Pamphlet 時(shí)間: 2025-3-26 02:32 作者: 不安 時(shí)間: 2025-3-26 07:56 作者: STALL 時(shí)間: 2025-3-26 10:25 作者: byline 時(shí)間: 2025-3-26 13:21 作者: Coronation 時(shí)間: 2025-3-26 17:56 作者: construct 時(shí)間: 2025-3-26 20:56 作者: Anterior 時(shí)間: 2025-3-27 03:59 作者: 良心 時(shí)間: 2025-3-27 07:04 作者: 關(guān)節(jié)炎 時(shí)間: 2025-3-27 13:10
Ricardo J. Rabelo,Alexandra A. Pereira-Klen techniques are basing on extension of the notion of approximate tandem repeat. Examples of correlation of latent profile periodicity revealed in the CDSs with structural–functional properties in the proteins are given.作者: chronicle 時(shí)間: 2025-3-27 15:36 作者: 迅速成長(zhǎng) 時(shí)間: 2025-3-27 18:10 作者: 好開(kāi)玩笑 時(shí)間: 2025-3-27 23:22 作者: 玩忽職守 時(shí)間: 2025-3-28 06:02
https://doi.org/10.1007/978-3-642-77684-7we were able to deduce a novel sensitive matrix, called MIQS, which shows better detection performance for detecting distantly related proteins than those of existing matrices. This approach to derive an efficient amino acid substitution matrix might influence many fields of protein sequence analysis. MIQS is available at ..作者: STYX 時(shí)間: 2025-3-28 07:31 作者: 和平 時(shí)間: 2025-3-28 12:37
Classification and Exploration of 3D Protein Domain Interactions Using Kbdocknteractions (DPIs) at the Pfam domain family level. We also briefly explain how the Kbdock web site works, and we provide some notes and suggestions which should help to avoid some common pitfalls when working with 3D protein domain structures.作者: gain631 時(shí)間: 2025-3-28 16:07 作者: Condyle 時(shí)間: 2025-3-28 19:25 作者: 我沒(méi)有命令 時(shí)間: 2025-3-29 02:28 作者: 抵制 時(shí)間: 2025-3-29 06:00 作者: 誓言 時(shí)間: 2025-3-29 07:14 作者: nettle 時(shí)間: 2025-3-29 12:14 作者: prostate-gland 時(shí)間: 2025-3-29 19:25
Spectral–Statistical Approach for Revealing Latent Regular Structures in DNA Sequence techniques are basing on extension of the notion of approximate tandem repeat. Examples of correlation of latent profile periodicity revealed in the CDSs with structural–functional properties in the proteins are given.作者: Engaged 時(shí)間: 2025-3-29 22:53 作者: Immunoglobulin 時(shí)間: 2025-3-30 01:56 作者: 耕種 時(shí)間: 2025-3-30 07:27
Joao Marcos De Oliveira,Peter A. Gloorproject, in which IntAct and MINT joined forces to create a single resource to improve curation and software development efforts. This is exemplified as a model for the future of molecular interaction data collation and dissemination.作者: 能夠支付 時(shí)間: 2025-3-30 08:54
Update on Genomic Databases and Resources at the National Center for Biotechnology Information biology of living organisms. This huge increase in DNA sequence data presents new challenges for the information management system and the visualization tools. New strategies have been designed to bring an order to this genome sequence shockwave and improve the usability of associated data.作者: 爭(zhēng)吵 時(shí)間: 2025-3-30 14:27
The MIntAct Project and Molecular Interaction Databasesproject, in which IntAct and MINT joined forces to create a single resource to improve curation and software development efforts. This is exemplified as a model for the future of molecular interaction data collation and dissemination.作者: Abjure 時(shí)間: 2025-3-30 19:56
Oliviero Carugo,Frank EisenhaberIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia作者: START 時(shí)間: 2025-3-30 21:21 作者: GUMP 時(shí)間: 2025-3-31 01:23
Collaborative Information Seekingunts of heterogeneous data. Data for genomes, genes, gene expressions, gene variation, gene families, proteins, and protein domains are integrated with the analytical, search, and retrieval resources through the NCBI website, text-based search and retrieval system, provides a fast and easy way to na作者: Albinism 時(shí)間: 2025-3-31 06:51 作者: NICE 時(shí)間: 2025-3-31 10:12 作者: 弄皺 時(shí)間: 2025-3-31 16:27
Collaborative Innovation Networkslly, protein stability is measured with circular dichroism, differential scanning calorimetry, and fluorescence spectroscopy using thermal and denaturant denaturation methods. These experimental data have been accumulated in the form of a database, ProTherm, thermodynamic database for proteins and m作者: 寬大 時(shí)間: 2025-3-31 18:58 作者: 使長(zhǎng)胖 時(shí)間: 2025-4-1 01:27
Collaborative Innovation Networksimization in drug development. Applying data mining techniques on these experimentally determined structures requires a highly uniform, standardized structural data source. The Protein Data Bank (PDB) has evolved over the years toward becoming the standard resource for macromolecular structures. How作者: 思想靈活 時(shí)間: 2025-4-1 02:39
Carlo Alberto Amadei,Monica Baraldi Borgida the subsets are non-redundant and of high quality. The first problem can be solved relatively easily at the sequence level or at the structural level. The second, on the contrary, needs special attention. It is not sufficient, in fact, to consider the crystallographic resolution and other feature m
