標(biāo)題: Titlebook: DNA and Histone Methylation as Cancer Targets; Atsushi Kaneda,Yu-ichi Tsukada Book 2017 Springer International Publishing AG 2017 Demethyl [打印本頁(yè)] 作者: 凝固 時(shí)間: 2025-3-21 17:32
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets影響因子(影響力)
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets被引頻次
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets被引頻次學(xué)科排名
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets年度引用
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets年度引用學(xué)科排名
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets讀者反饋
書(shū)目名稱(chēng)DNA and Histone Methylation as Cancer Targets讀者反饋學(xué)科排名
作者: Suppository 時(shí)間: 2025-3-21 22:12
The Molecular Basis of DNA Methylationand is crucial for development, especially in higher eukaryotes. Three DNA (cytosine-5)-methyltransferases, Dnmt1, Dnmt3a, and Dnmt3b, have been identified. Dnmt3a and Dnmt3b are mainly responsible for establishing DNA methylation patterns in the genome. Factors interacting with Dnmt3a or Dnmt3b, hi作者: hangdog 時(shí)間: 2025-3-22 00:35
The Molecular Basis of DNA Demethylationng DNA methylation have been well characterized, those involved in demethylation have remained elusive until recently. Mounting evidence now suggests that the TET proteins, a family of AlkB-like Fe(II)/α-ketoglutarate-dependent dioxygenases, initiate active DNA demethylation by oxidizing 5-methylcyt作者: 巨頭 時(shí)間: 2025-3-22 07:47 作者: decode 時(shí)間: 2025-3-22 10:34 作者: overrule 時(shí)間: 2025-3-22 16:02 作者: overrule 時(shí)間: 2025-3-22 17:53 作者: 小步走路 時(shí)間: 2025-3-23 00:59
Misregulation of Histone Methylation Regulators in Cancerl processes through divergent transcription activities. Recently, aberrant histone modifications have been shown to contribute significantly towards many diseases, notably cancer. Here, we summarize the known drivers leading to misregulation of DNA and histone methylation in cancer, and current ther作者: Amplify 時(shí)間: 2025-3-23 04:21 作者: 剛毅 時(shí)間: 2025-3-23 07:47
DNA Methylation and Dysregulation of miRNA in Cancerthe expression of protein coding/noncoding RNAs by repressing translation or cleaving RNA transcripts in a sequence-depending manner. The unique characteristic function of miRNAs is to regulate RNA transcripts in human cells. Therefore, dysregulated expression of miRNAs can disrupt tightly regulated作者: 爭(zhēng)吵加 時(shí)間: 2025-3-23 13:16 作者: 包裹 時(shí)間: 2025-3-23 15:57
DNA and Histone Methylation in Brain Cancerifferent malignant stages, including histologically benign forms and highly aggressive states, most gliomas are clinically challenging for neuro-oncologists because of their infiltrative growth patterns and inherent relapse tendency with increased malignancy and dismal prognosis. Extensive genetic a作者: Endoscope 時(shí)間: 2025-3-23 20:51
DNA and Histone Methylation in Gastric Cancerwith aberrant DNA hypermethylation as well as genetic alterations, and the both these infectious agents are involved in various molecular events. This chapter focuses on epigenetic aberrations in gastric cancer, including hypermethylation and its correlations with the two infectious agents as well a作者: Myofibrils 時(shí)間: 2025-3-24 01:41 作者: 結(jié)果 時(shí)間: 2025-3-24 03:13
DNA and Histone Methylation in Lung Cancer and DNA repair/housekeeping genes. One of the major clinical needs is the discovery and clinical validation of new molecular biomarkers using non-or minimally invasive procedures to assist early diagnosis, prognosis and prediction of response to treatment. Histone methylation has profound effects o作者: Etching 時(shí)間: 2025-3-24 08:35
Atsushi Kaneda,Yu-ichi TsukadaDescribes the features of DNA and histone methylation associated with particular types of cancer.Compiles the current knowledge of the molecular basis of DNA and histone methylation and contextualizes作者: 設(shè)施 時(shí)間: 2025-3-24 14:23 作者: Infirm 時(shí)間: 2025-3-24 18:24
Nikki J. Y. Lee,Julian Stringerogical development including but not limited to cell fate determination, maintenance of tissue differentiation, and cancer occurrence. Methylation of DNA and histones, the two components of chromatin, constitutes important epigenetic mechanisms that govern chromatin-based nuclear processes. In this 作者: zonules 時(shí)間: 2025-3-24 20:25
Chinese Firms Between Hierarchy and Marketand is crucial for development, especially in higher eukaryotes. Three DNA (cytosine-5)-methyltransferases, Dnmt1, Dnmt3a, and Dnmt3b, have been identified. Dnmt3a and Dnmt3b are mainly responsible for establishing DNA methylation patterns in the genome. Factors interacting with Dnmt3a or Dnmt3b, hi作者: 軟膏 時(shí)間: 2025-3-24 23:36
The Structural Features of the CMRSng DNA methylation have been well characterized, those involved in demethylation have remained elusive until recently. Mounting evidence now suggests that the TET proteins, a family of AlkB-like Fe(II)/α-ketoglutarate-dependent dioxygenases, initiate active DNA demethylation by oxidizing 5-methylcyt作者: 氣候 時(shí)間: 2025-3-25 05:05
A Review of the Institutional Perspective reflect altered signalling/gene regulatory networks and may directly contribute to the disease state. In this short review we will focus on how DNA modification changes have contributed to our understanding of cancer progression and the hypothesis that cancer cells have an epigenome reflecting alte作者: 受傷 時(shí)間: 2025-3-25 10:38 作者: 愛(ài)了嗎 時(shí)間: 2025-3-25 14:59
Liao-Chai-Chih-Iby P’u Sung-Lingsidues and plays pivotal roles in the regulation of chromatin organization and function. Histone methylation is catalyzed by different groups of methyltransferases while methylation marks on different residues as well as different methylation states on the same residue serve as docking sites to recr作者: GRATE 時(shí)間: 2025-3-25 16:39
History and Epics in China and in the Westal modifications controlling gene expression. When gene expression goes awry, disease ensues and often this disease is some form of cancer. Thus, an understanding of histone tail modification in nucleosomes is critical in mankind’s attempts to eradicate cancers. This chapter examines our present kno作者: neologism 時(shí)間: 2025-3-25 20:48
Xiaobo Wu,Wanling Ding,Yongjiang Shil processes through divergent transcription activities. Recently, aberrant histone modifications have been shown to contribute significantly towards many diseases, notably cancer. Here, we summarize the known drivers leading to misregulation of DNA and histone methylation in cancer, and current ther作者: 的染料 時(shí)間: 2025-3-26 01:09 作者: vascular 時(shí)間: 2025-3-26 05:40 作者: Flavouring 時(shí)間: 2025-3-26 08:40 作者: 新鮮 時(shí)間: 2025-3-26 16:11
Freedom Mazwi,George T. Mudimu,Kirk Hellikerifferent malignant stages, including histologically benign forms and highly aggressive states, most gliomas are clinically challenging for neuro-oncologists because of their infiltrative growth patterns and inherent relapse tendency with increased malignancy and dismal prognosis. Extensive genetic a作者: 情感 時(shí)間: 2025-3-26 17:50
https://doi.org/10.1007/978-3-031-38913-9with aberrant DNA hypermethylation as well as genetic alterations, and the both these infectious agents are involved in various molecular events. This chapter focuses on epigenetic aberrations in gastric cancer, including hypermethylation and its correlations with the two infectious agents as well a作者: Tempor 時(shí)間: 2025-3-27 00:41 作者: evince 時(shí)間: 2025-3-27 04:06
Shida Li,Wenjie Zhou,Yunfang Wu and DNA repair/housekeeping genes. One of the major clinical needs is the discovery and clinical validation of new molecular biomarkers using non-or minimally invasive procedures to assist early diagnosis, prognosis and prediction of response to treatment. Histone methylation has profound effects o作者: Ceramic 時(shí)間: 2025-3-27 07:20
https://doi.org/10.1007/978-3-319-59786-7Demethylation; DNA; Histone; Hypermethylation; Methylation作者: 生來(lái) 時(shí)間: 2025-3-27 12:00
978-3-319-86700-7Springer International Publishing AG 2017作者: 僵硬 時(shí)間: 2025-3-27 17:10
DNA and Histone Methylation as Cancer Targets978-3-319-59786-7Series ISSN 2196-9906 Series E-ISSN 2196-9914 作者: Conspiracy 時(shí)間: 2025-3-27 18:47
Xiaobo Wu,Wanling Ding,Yongjiang Shil processes through divergent transcription activities. Recently, aberrant histone modifications have been shown to contribute significantly towards many diseases, notably cancer. Here, we summarize the known drivers leading to misregulation of DNA and histone methylation in cancer, and current therapeutic options to counter these aberrations.作者: 消瘦 時(shí)間: 2025-3-28 00:59 作者: modest 時(shí)間: 2025-3-28 02:41
Misregulation of Histone Methylation Regulators in Cancerl processes through divergent transcription activities. Recently, aberrant histone modifications have been shown to contribute significantly towards many diseases, notably cancer. Here, we summarize the known drivers leading to misregulation of DNA and histone methylation in cancer, and current therapeutic options to counter these aberrations.作者: committed 時(shí)間: 2025-3-28 07:25 作者: 清楚說(shuō)話 時(shí)間: 2025-3-28 12:51
The Molecular Basis of Histone Methylationf binding proteins at multiple molecular layers. Given?that the disruption of histone methylation and recognition has been associated with altered gene function in various diseases and human malignancy, understanding the regulation of histone methylation and recognition will also provide molecular b作者: 接觸 時(shí)間: 2025-3-28 18:21
The Molecular Basis of Histone Demethylation aspects of all seven known KDM families are reviewed as well as our present knowledge of their involvement in cancers. Control of their aberrant behavior by design of chemical inhibitors, that have the potential to be powerful cancer fighting drugs, is an expanding human endeavor and is chronicled 作者: molest 時(shí)間: 2025-3-28 19:12 作者: Flatter 時(shí)間: 2025-3-29 02:33
DNA Methylation and Dysregulation of miRNA in Cancerrs, including DNA methyltransferases (DNMTs), histone deacetylases (HDACs), and polycomb group genes. When this complicated feedback loop between miRNAs and epigenetics is dysregulated by aberrant expression of miRNAs, normal physiological functions are disrupted, and as a result, several diseases o作者: Decibel 時(shí)間: 2025-3-29 06:55
Genomic Imprinting Syndromes and Cancer general imprinting mechanisms, representative clinical features and causative molecular alterations of eight imprinting syndromes are described. In addition, representative molecular alterations of imprinted DMRs or imprinted genes associated with tumors are also described.作者: conference 時(shí)間: 2025-3-29 09:15
DNA and Histone Methylation in Brain Cancerng enzymatic modifications to DNA or histone proteins, thereby regulating gene expression, are increasingly recognized as a source of phenotypic variability in biology. Of epigenetic marks, DNA and histone methylation is a key mark that regulates gene expression and thus modulates a wide range of on作者: MINT 時(shí)間: 2025-3-29 12:59
Liao-Chai-Chih-Iby P’u Sung-Lingf binding proteins at multiple molecular layers. Given?that the disruption of histone methylation and recognition has been associated with altered gene function in various diseases and human malignancy, understanding the regulation of histone methylation and recognition will also provide molecular b作者: defendant 時(shí)間: 2025-3-29 18:42
History and Epics in China and in the West aspects of all seven known KDM families are reviewed as well as our present knowledge of their involvement in cancers. Control of their aberrant behavior by design of chemical inhibitors, that have the potential to be powerful cancer fighting drugs, is an expanding human endeavor and is chronicled 作者: Stress-Fracture 時(shí)間: 2025-3-29 21:27
Yun Schüler-Zhou,Margot Schüller,Magnus Brodd by histone deacetylases. This chapter focuses on outlining representative histone acetyltransferases and their molecular mechanisms, to provide a picture of how their substrate-specificity is ensured. Next, how bromodomains recognize their target residues is presented. Finally, the molecular mecha作者: Rodent 時(shí)間: 2025-3-30 00:15 作者: 做事過(guò)頭 時(shí)間: 2025-3-30 04:38 作者: 并排上下 時(shí)間: 2025-3-30 08:41
Freedom Mazwi,George T. Mudimu,Kirk Hellikerng enzymatic modifications to DNA or histone proteins, thereby regulating gene expression, are increasingly recognized as a source of phenotypic variability in biology. Of epigenetic marks, DNA and histone methylation is a key mark that regulates gene expression and thus modulates a wide range of on作者: OGLE 時(shí)間: 2025-3-30 15:33
2196-9906 ular basis of DNA and histone methylation and contextualizes.This book will focus on DNA and histone methylation in epigenetics and describe how it is involved in the molecular mechanisms responsible for the development of cancer. Chapters will summarize the current knowledge of the molecular basis 作者: PAC 時(shí)間: 2025-3-30 16:51
