標(biāo)題: Titlebook: DNA Vaccines; Methods and Protocol Douglas B. Lowrie,Robert G. Whalen Book 2000 Springer Science+Business Media New York 2000 [打印本頁] 作者: 指責(zé) 時(shí)間: 2025-3-21 16:57
書目名稱DNA Vaccines影響因子(影響力)
書目名稱DNA Vaccines影響因子(影響力)學(xué)科排名
書目名稱DNA Vaccines網(wǎng)絡(luò)公開度
書目名稱DNA Vaccines網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱DNA Vaccines被引頻次
書目名稱DNA Vaccines被引頻次學(xué)科排名
書目名稱DNA Vaccines年度引用
書目名稱DNA Vaccines年度引用學(xué)科排名
書目名稱DNA Vaccines讀者反饋
書目名稱DNA Vaccines讀者反饋學(xué)科排名
作者: 骨 時(shí)間: 2025-3-21 23:39 作者: patriarch 時(shí)間: 2025-3-22 02:45
On Automatic Design of Neuro-fuzzy Systemsonkeys (.), . in mice (.,.), malaria in mice (.,.), and genital herpes simplex virus in guinea pigs (.). Recently, DNA vaccines for the protection against influenza (Merck Research Laboratories, Rahway, NJ), malaria (Vical Inc., San Diego, CA), and HIV (Apollon Inc., Philadelphia, PA), have entered 作者: innovation 時(shí)間: 2025-3-22 06:30 作者: meditation 時(shí)間: 2025-3-22 10:24
Ana Starcevic,Boris Vucinic,Ilona Karpiel’s cells and induce expression of the transgene. Moreover, immunization with purified TAA peptides or with antigen-presenting cells, such as dendritic cells, pulsed with TAA peptides have been proposed.作者: Acumen 時(shí)間: 2025-3-22 13:44
Ashlesha Kumar,Kuldip Singh Sangwan,Dhiraj IL-12 and IFN-γ, with little secretion of Th2 cytokines (.,.). These effects can also be obtained with synthetic oligonucleotides (ODN) (.,.) or plasmid DNA vectors (.) containing CpG immunostimulatory motifs. From a teleological view, it appears likely that the rapid immune activation in response 作者: Acumen 時(shí)間: 2025-3-22 18:55
Artificial Intelligence and Soft Computing7 [.–.], and GM-CSF [.,.]), chemokines (TCA-3 [.], RANTES [.], MIP-1 [.]), and costimulatory molecules (CD40L [.], B7-1 [.] and B7-2 [.]) could enhance or modify the specific immune responses elicited by DNA immunization (. .).作者: PANG 時(shí)間: 2025-3-22 23:52
Development and Characterization of Lyophilized DNA Vaccine Formulations,onkeys (.), . in mice (.,.), malaria in mice (.,.), and genital herpes simplex virus in guinea pigs (.). Recently, DNA vaccines for the protection against influenza (Merck Research Laboratories, Rahway, NJ), malaria (Vical Inc., San Diego, CA), and HIV (Apollon Inc., Philadelphia, PA), have entered 作者: Phonophobia 時(shí)間: 2025-3-23 04:21 作者: infatuation 時(shí)間: 2025-3-23 06:12 作者: 河流 時(shí)間: 2025-3-23 10:17 作者: chalice 時(shí)間: 2025-3-23 14:00
Cytokine and Costimulatory Factor-Encoding Plasmids as Adjuvants for DNA Vaccination,7 [.–.], and GM-CSF [.,.]), chemokines (TCA-3 [.], RANTES [.], MIP-1 [.]), and costimulatory molecules (CD40L [.], B7-1 [.] and B7-2 [.]) could enhance or modify the specific immune responses elicited by DNA immunization (. .).作者: Geyser 時(shí)間: 2025-3-23 19:22 作者: white-matter 時(shí)間: 2025-3-23 23:16 作者: mosque 時(shí)間: 2025-3-24 04:35 作者: 鞭打 時(shí)間: 2025-3-24 10:30
On Automatic Design of Neuro-fuzzy Systemsications in the past few years. Injection of mouse muscle with naked DNA (plasmid DNA in saline) resulted in significant episomal expression from a number of encoded reporter genes such as firefly luciferase, chloramphenicol acetyltransferase, and β-galactosidase (.). DNA vaccination has been shown 作者: 失眠癥 時(shí)間: 2025-3-24 13:31
Lecture Notes in Computer Scienceally each immunized by injection of 100 μg on four occasions, so that an experiment with 50 mice requires 20 mg DNA as a minimum. The Qiagen tip-10,000 (Giga) column is intended to deliver up to 10 mg of high copy-number plasmid DNA from .. We have found that by repeatedly regenerating the column an作者: 輪流 時(shí)間: 2025-3-24 15:27
Lecture Notes in Computer Science of antibody responses, demonstrated that injection of “naked” DNA could result in antigen expression in an immunogenic form (.). This observation and the subsequent demonstration that intramuscular injections of plasmid DNA encoding influenza nucleoprotein could protect mice against a challenge wit作者: ANT 時(shí)間: 2025-3-24 20:00 作者: concubine 時(shí)間: 2025-3-25 00:59
Artificial Intelligence and Soft Computingl (i.d.) injection of pure plasmid DNA (“naked” DNA), or biolistic introduction of DNA-coated gold particles into the epidermis with a “gene gun.” It is also possible to deliver naked or liposome-formulated DNA to mucosal surfaces.作者: blight 時(shí)間: 2025-3-25 03:35
Artificial Intelligence and Soft Computingsponse; live infectious agents and inactivated or subunit vaccine preparations. Live infectious agents generally are most efficacious, but there is always a risk factor when using this type of vaccine. The major advantage of inactivated and subunit preparations is their safety; however, limited effi作者: 爭吵 時(shí)間: 2025-3-25 11:28 作者: 過份 時(shí)間: 2025-3-25 13:22 作者: 要控制 時(shí)間: 2025-3-25 18:36 作者: 嬉耍 時(shí)間: 2025-3-25 23:27 作者: 單挑 時(shí)間: 2025-3-26 02:26
Artificial Intelligence and Soft Computingof cancer, autoimmunity, and allergy (.). Until recently, however, the cellular events by which injected plasmid DNA elicits potent antibody and cytotoxic T-lymphocyte (CTL) responses were largely unknown. Upon intramuscular (i.m.) injection of naked DNA, predominant expression of transfected DNA oc作者: Irrepressible 時(shí)間: 2025-3-26 06:28 作者: micronutrients 時(shí)間: 2025-3-26 10:59 作者: Callus 時(shí)間: 2025-3-26 12:59
Artificial Intelligence and Soft Computinglate and deliver purified plasmid DNA into mouse tissues. They discovered that direct injection of lipid-DNA complexes into muscle resulted in measurable protein expression. A belated control experiment without lipid led to the serendipitous discovery that “naked” plasmid DNA was taken up and expres作者: detach 時(shí)間: 2025-3-26 18:41
Artificial Intelligence and Soft Computing induce markedly stronger CD8. cytotoxic T lymphocyte (CTL) activity than do traditional peptide vaccines through their particular mechanism of antigen presentation mediated by MHC class I molecules. Induction of CTL specific to pathogenic viruses is thought to provide a reliable means of protecting作者: 合并 時(shí)間: 2025-3-26 22:51 作者: 描述 時(shí)間: 2025-3-27 03:35
Production of Plasmid DNA in Industrial Quantities According to cGMP Guidelines,sary to develop an easy, cost-effective, industrial scale process for production of plasmid DNA (. .). One main issue is that the process should conform to cGMP guidelines and be acceptable to the FDA or other national regulatory agencies. The cGMP environment should be implemented independently of the intended use of the DNA product.作者: inspired 時(shí)間: 2025-3-27 07:53 作者: Ganglion-Cyst 時(shí)間: 2025-3-27 09:56 作者: Ingrained 時(shí)間: 2025-3-27 16:52
DNA Vaccines978-1-59259-688-1Series ISSN 1543-1894 Series E-ISSN 1940-6037 作者: 整頓 時(shí)間: 2025-3-27 17:59 作者: vascular 時(shí)間: 2025-3-27 22:12
Artificial Intelligence and Soft Computingl (i.d.) injection of pure plasmid DNA (“naked” DNA), or biolistic introduction of DNA-coated gold particles into the epidermis with a “gene gun.” It is also possible to deliver naked or liposome-formulated DNA to mucosal surfaces.作者: HILAR 時(shí)間: 2025-3-28 05:14 作者: LAST 時(shí)間: 2025-3-28 07:06 作者: septicemia 時(shí)間: 2025-3-28 12:07
Repeated Use of Qiagen Columns in Large-Scale Preparation of Plasmid DNA,0 (Giga) column is intended to deliver up to 10 mg of high copy-number plasmid DNA from .. We have found that by repeatedly regenerating the column and reapplying the flowthrough volume of DNA extract, we can readily obtain 2–4-fold increased yields, up to 40 mg, from the standard 2.5 L broth culture.作者: 案發(fā)地點(diǎn) 時(shí)間: 2025-3-28 15:11 作者: 伙伴 時(shí)間: 2025-3-28 22:42
Artificial Intelligence and Soft Computingcacy and duration of immunity and/or high cost may limit the usefulness of these types of vaccines. DNA vaccines represent a new and potentially powerful approach to the development of subunit vaccines.作者: Apoptosis 時(shí)間: 2025-3-28 23:28 作者: 爭論 時(shí)間: 2025-3-29 03:15 作者: 羽毛長成 時(shí)間: 2025-3-29 11:00
https://doi.org/10.1007/978-3-319-19324-3s led to a need to increase the level of supercoiled plasmid purity as well as the methodology utilized to produce these plasmids at large scale. Several parameters of the purification process need to be addressed:作者: itinerary 時(shí)間: 2025-3-29 15:15 作者: 動機(jī) 時(shí)間: 2025-3-29 16:19 作者: 未成熟 時(shí)間: 2025-3-29 23:44
In Vitro Assay of Immunostimulatory Activities of Plasmid Vectors,o the immune system. Although the trafficking of the plasmid and its protein product is not well understood, the generation of responses ultimately involves a bone marrow-derived antigen presenting cell (.).作者: 大吃大喝 時(shí)間: 2025-3-30 02:09
Optimization of DNA Vaccines Through the Use of Molecular Adjuvants,lls, which become the in vivo protein source for the production of antigen. This antigen then is the focus of the resulting immune response. This vaccination technique is being explored as an immunization strategy against a variety of infectious diseases as well as cancer.作者: SEMI 時(shí)間: 2025-3-30 05:14
Book 2000 in the scientific literature of the last decades. However, the present state of affairs appears to date from observations made discreetly in 1988 by Wolff, Malone, Felgner, and colleagues, which were described in a 1989 patent and published in 1990. Quite surprisingly, they showed that genes carrie作者: 健談 時(shí)間: 2025-3-30 11:53
1543-1894 d- cerned in the scientific literature of the last decades. However, the present state of affairs appears to date from observations made discreetly in 1988 by Wolff, Malone, Felgner, and colleagues, which were described in a 1989 patent and published in 1990. Quite surprisingly, they showed that ge作者: largesse 時(shí)間: 2025-3-30 15:57 作者: Foregery 時(shí)間: 2025-3-30 16:56 作者: Ophthalmologist 時(shí)間: 2025-3-30 21:35 作者: HILAR 時(shí)間: 2025-3-31 04:41 作者: 織布機(jī) 時(shí)間: 2025-3-31 07:24
Artificial Intelligence and Soft Computingting the antigenic peptide on their MHC class I molecules. Alternatively, the priming of CTLs may be mediated by professional APC taking up antigen released from muscle cells. Finally, CTL priming may involve direct transfection of APC occurring, albeit at low level, and that the CTLs are activated by the transfected APC.作者: xanthelasma 時(shí)間: 2025-3-31 09:20 作者: 高興一回 時(shí)間: 2025-3-31 14:56
Intramuscular Injection of DNA Vaccines in Fish,pecific DNA sequences (CpG motifs), in a particular nucleotide context, act as immunostimulants (.,.). No study has been reported yet assessing these immunostimulatory sequences in fish, but it would be unlikely that the same sequences are effective in all animal species (Weeratna et al., this volume).作者: 新手 時(shí)間: 2025-3-31 20:35
Development of DNA Vaccines for Salmonid Fish,r advantages are the elimination of any possibility of reversion to virulence since the DNA vaccine encodes only a portion of the viral genome, the relative stability of the DNA preparation; the ease of DNA preparation; and, importantly, the elicitation of a robust immune response in fish.作者: aggrieve 時(shí)間: 2025-4-1 00:11
The Use of Bone Marrow-Chimeric Mice in Determining the MHC Restriction of Epitope-Specific Cytotoxting the antigenic peptide on their MHC class I molecules. Alternatively, the priming of CTLs may be mediated by professional APC taking up antigen released from muscle cells. Finally, CTL priming may involve direct transfection of APC occurring, albeit at low level, and that the CTLs are activated by the transfected APC.作者: Alopecia-Areata 時(shí)間: 2025-4-1 04:36 作者: Dawdle 時(shí)間: 2025-4-1 06:13