標(biāo)題: Titlebook: DNA Repair and Human Disease; Adayabalam S. Balajee Book 2006 Springer-Verlag US 2006 DNA.DNA repair.Telomere.Xeroderma pigmentosum.aging. [打印本頁] 作者: 太平間 時(shí)間: 2025-3-21 16:13
書目名稱DNA Repair and Human Disease影響因子(影響力)
書目名稱DNA Repair and Human Disease影響因子(影響力)學(xué)科排名
書目名稱DNA Repair and Human Disease網(wǎng)絡(luò)公開度
書目名稱DNA Repair and Human Disease網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱DNA Repair and Human Disease被引頻次
書目名稱DNA Repair and Human Disease被引頻次學(xué)科排名
書目名稱DNA Repair and Human Disease年度引用
書目名稱DNA Repair and Human Disease年度引用學(xué)科排名
書目名稱DNA Repair and Human Disease讀者反饋
書目名稱DNA Repair and Human Disease讀者反饋學(xué)科排名
作者: patriot 時(shí)間: 2025-3-21 21:42
https://doi.org/10.1007/978-3-030-80606-4oth transcription and NER. . and . encode two subunits of TFIIH, and also TTDA has been recendy identified as a new component of the TFIIH complex. The discovery of this unexpected link between DNA repair and transcription was crucial to rationalize the TTD pathological phenotype as well as the puzz作者: 牛馬之尿 時(shí)間: 2025-3-22 01:57
https://doi.org/10.1007/978-3-642-31322-6BRCA1 in discrete nuclear .. FANCD2 is also independently phosphorylated by ATM in response to ionising radiation and interacts with the MRE1 l/Rad50/NBSl complex, which is directly involved in homologous recombination DNA repair pathway and in cell cycle checkpoint response to DNA damage. Available作者: Nostalgia 時(shí)間: 2025-3-22 05:36
https://doi.org/10.1007/978-3-642-31322-6eview is focused on the potential functions of . in both DNA repair and cell cycle checkpoint regulation and how deficiencies in these overlapping functions can lead to some of the phenotypic features of AT patients.作者: aggravate 時(shí)間: 2025-3-22 12:43
https://doi.org/10.1007/978-3-030-37293-4cells has identified the involvement of potential DNA repair factors in such pathways. Studies by us and others have shown the association between the DNA repair factors and telomere function in mammalian cells. Mice deficient in a DNA-break sensing molecule, PARP-1 (poly [ADP]-ribopolymerase), have作者: Radiculopathy 時(shí)間: 2025-3-22 14:04
Human Premature Aging Disorders and Dysfunction of DNA Repair,ocalization studies all suggest WRN’s participation in multiple DNA metabolic pathways for maintaining genomic integrity. CS arises from mutations in the CSA and CSB genes. While CSA belongs to “WD” repeat containing protein family, CSB is a member of SNF2-like family with only a DNA stimulated ATPa作者: Radiculopathy 時(shí)間: 2025-3-22 19:14
Trichothiodystrophy,oth transcription and NER. . and . encode two subunits of TFIIH, and also TTDA has been recendy identified as a new component of the TFIIH complex. The discovery of this unexpected link between DNA repair and transcription was crucial to rationalize the TTD pathological phenotype as well as the puzz作者: 有法律效應(yīng) 時(shí)間: 2025-3-22 23:05
The Fanconi Anemia/BRCA Pathway,BRCA1 in discrete nuclear .. FANCD2 is also independently phosphorylated by ATM in response to ionising radiation and interacts with the MRE1 l/Rad50/NBSl complex, which is directly involved in homologous recombination DNA repair pathway and in cell cycle checkpoint response to DNA damage. Available作者: cardiovascular 時(shí)間: 2025-3-23 04:53
Is Ataxia Telangiectasia a Result of Impaired Coordination between DNA Repair and Cell Cycle Checkpeview is focused on the potential functions of . in both DNA repair and cell cycle checkpoint regulation and how deficiencies in these overlapping functions can lead to some of the phenotypic features of AT patients.作者: 檔案 時(shí)間: 2025-3-23 08:54
Orchestration of Telomeres and DNA Repair Factors in Mammalian Cells,cells has identified the involvement of potential DNA repair factors in such pathways. Studies by us and others have shown the association between the DNA repair factors and telomere function in mammalian cells. Mice deficient in a DNA-break sensing molecule, PARP-1 (poly [ADP]-ribopolymerase), have作者: HERTZ 時(shí)間: 2025-3-23 12:50 作者: d-limonene 時(shí)間: 2025-3-23 14:31 作者: iodides 時(shí)間: 2025-3-23 19:12 作者: 昏暗 時(shí)間: 2025-3-23 23:44
Oberes Sprunggelenk — Spezieller Teiled by premature onset of age-related phenotypic changes (such as cataract and greying of hair etc) and genome instability. Cells derived from CS patients are defective in DNA repair, and CS patients display severe neurological abnormalities and certain features of premature aging. The accelerated ag作者: insurgent 時(shí)間: 2025-3-24 05:37
Oberes Sprunggelenk — Allgemeiner Teilpress illegitimate recombination, particularly during the repair of DNA double strand breaks. Five . family genes have been identified in humans, and three (., and .) have been identified as defective in the human genetic disorders; Bloom syndrome, Werner syndrome, and a subset of Rothmund-Thomson s作者: 開始發(fā)作 時(shí)間: 2025-3-24 10:15 作者: 重疊 時(shí)間: 2025-3-24 12:12 作者: BOOR 時(shí)間: 2025-3-24 16:47 作者: 越自我 時(shí)間: 2025-3-24 22:09
https://doi.org/10.1007/978-3-642-31322-6ility and DNA repair pathways that have evolved in the human genome to prevent the harmful effects of exposure to DNA damaging agents. One such disorder is Fanconi Anemia, an autosomal recessive disease characterized by an increased spontaneous and DNA cross-linkers induced chromosome instability, p作者: Arable 時(shí)間: 2025-3-25 01:04
https://doi.org/10.1007/978-3-642-31322-6langiectasia, immunodeficiency, chromosomal instability and radio sensitivity with an increased predisposition to lymphoid cancer in childhood. The gene responsible for AT, ataxia telangiectasia mutated (ATM), has been cloned and its protein product has been biochemically characterized as a serine/t作者: majestic 時(shí)間: 2025-3-25 05:14 作者: 生意行為 時(shí)間: 2025-3-25 09:12 作者: 商品 時(shí)間: 2025-3-25 12:25
Book 2006.DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries. .作者: Minatory 時(shí)間: 2025-3-25 16:14 作者: 羽毛長成 時(shí)間: 2025-3-25 22:27
978-1-4899-9899-6Springer-Verlag US 2006作者: 激怒某人 時(shí)間: 2025-3-26 01:29 作者: 分開如此和諧 時(shí)間: 2025-3-26 07:59
tational inactivation of a single gene leads to complex phen.DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries. .978-1-4899-9899-6978-0-387-36802-3作者: Mangle 時(shí)間: 2025-3-26 11:18
https://doi.org/10.1007/978-3-030-37293-4As highlighted above, the role of oxidative stress in the pathogenesis of AD is a burgeoning field. However, while much is known, much remains unknown as to the impact of therapeutic intervention in patients with disease. Translation of basic scientific findings into efficacious treatment strategies remains to be determined.作者: Adulterate 時(shí)間: 2025-3-26 15:00 作者: 擔(dān)憂 時(shí)間: 2025-3-26 19:47
Human Premature Aging Disorders and Dysfunction of DNA Repair,ed by premature onset of age-related phenotypic changes (such as cataract and greying of hair etc) and genome instability. Cells derived from CS patients are defective in DNA repair, and CS patients display severe neurological abnormalities and certain features of premature aging. The accelerated ag作者: 600 時(shí)間: 2025-3-27 00:53
DNA Repair Aspects for RecQ Helicase Disorders,press illegitimate recombination, particularly during the repair of DNA double strand breaks. Five . family genes have been identified in humans, and three (., and .) have been identified as defective in the human genetic disorders; Bloom syndrome, Werner syndrome, and a subset of Rothmund-Thomson s作者: 驚奇 時(shí)間: 2025-3-27 03:54
Trichothiodystrophy,dation, ichthyosis, and, in many patients, cutaneous photosensitivity but no cancer incidence. All sun-sensitive TTD cases appear to be defective in nudeotide excision repair (NER) as a consequence of alterations in one of three genes, namely . and .. Intriguingly, in view of the very marked differe作者: 內(nèi)部 時(shí)間: 2025-3-27 05:43
Roles of the BRCA1 and BRCA2 Breast Cancer Susceptibility Proteins in DNA Repair,encoded proteins. BRCA1 and BRCA2 have now been linked to a wide variety of cellular functions through binding or colocalization with other proteins. In this chapter we focus on the best characterized of these potential functions, DNA repair.作者: Rct393 時(shí)間: 2025-3-27 09:29
Radiosensitivity of Cells Derived from Down Syndrome Patients,mental retardation accompanied by an increased incidence of cancer development in various tissues and organs. DS patients also show signs of premature aging phenotypes. Many of the phenotypic features of DS patients are presumably due to the excess of genetic material of chromosome 21. Cells derived作者: Ptosis 時(shí)間: 2025-3-27 13:44 作者: 多產(chǎn)魚 時(shí)間: 2025-3-27 19:13 作者: REP 時(shí)間: 2025-3-28 01:17 作者: 先兆 時(shí)間: 2025-3-28 03:44
Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients,esult in multisystem disorders. Mutations in the same gene can result in different clinical outcomes and severity depending on the site of a mutation and the gene dosage. This is further complicated by the possibility of pleiotropic effects caused by disturbances in other cellular processes. While n作者: etidronate 時(shí)間: 2025-3-28 09:17
Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients,ot discussed here, attempts to recapitulate the human genotype-phenotype relationships using transgenic mice are providing valuable insights into these disorders. It may soon be possible to determine a patient’s clinical prognosis by analyzing the site of the mutation in the affected gene.作者: cavity 時(shí)間: 2025-3-28 14:17
tational inactivation of a single gene leads to complex phen.DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries. .978-1-4899-9899-6978-0-387-36802-3作者: THROB 時(shí)間: 2025-3-28 15:38 作者: HUMP 時(shí)間: 2025-3-28 20:22
Oberes Sprunggelenk — Allgemeiner Teilns and hypermutability observed in cultured cells. These data suggest that each of these helicases contributes to maintaining genomic stability and that an important function of these helicases appears to be the resolution of recombination intermediates.作者: 平常 時(shí)間: 2025-3-29 01:23
DNA Repair Aspects for RecQ Helicase Disorders,ns and hypermutability observed in cultured cells. These data suggest that each of these helicases contributes to maintaining genomic stability and that an important function of these helicases appears to be the resolution of recombination intermediates.作者: BATE 時(shí)間: 2025-3-29 03:25
Radiosensitivity of Cells Derived from Down Syndrome Patients, aging phenotypes. Many of the phenotypic features of DS patients are presumably due to the excess of genetic material of chromosome 21. Cells derived from DS patients show abnormal response to ionizing radiation-induced DNA damage, and this review deals with some aspects of the radiosensitive phenotype in DS.作者: 著名 時(shí)間: 2025-3-29 10:06
Arthur Miller and American Tragedyot discussed here, attempts to recapitulate the human genotype-phenotype relationships using transgenic mice are providing valuable insights into these disorders. It may soon be possible to determine a patient’s clinical prognosis by analyzing the site of the mutation in the affected gene.作者: MAIM 時(shí)間: 2025-3-29 13:35
Book 1998a history and readings of the many praise and commemorative poems to or about Keats (collected in an appendix) from the time of his early death up to the present day and a consequent rethinking of Keats‘s own poems and poetics. Keats emerges as a poet uniquely available and useful to the experimenta作者: Chameleon 時(shí)間: 2025-3-29 18:42
