標(biāo)題: Titlebook: DNA Helicases and DNA Motor Proteins; Maria Spies Book 2013 The Editor(s) (if applicable) and The Author(s), under exclusive license to Sp [打印本頁] 作者: 高出來的名詞 時(shí)間: 2025-3-21 16:27
書目名稱DNA Helicases and DNA Motor Proteins影響因子(影響力)
書目名稱DNA Helicases and DNA Motor Proteins影響因子(影響力)學(xué)科排名
書目名稱DNA Helicases and DNA Motor Proteins網(wǎng)絡(luò)公開度
書目名稱DNA Helicases and DNA Motor Proteins網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱DNA Helicases and DNA Motor Proteins被引頻次
書目名稱DNA Helicases and DNA Motor Proteins被引頻次學(xué)科排名
書目名稱DNA Helicases and DNA Motor Proteins年度引用
書目名稱DNA Helicases and DNA Motor Proteins年度引用學(xué)科排名
書目名稱DNA Helicases and DNA Motor Proteins讀者反饋
書目名稱DNA Helicases and DNA Motor Proteins讀者反饋學(xué)科排名
作者: 條約 時(shí)間: 2025-3-21 23:30
Structure and Mechanisms of SF1 DNA Helicases, involved in essential processes in both DNA and RNA metabolism in all organisms. In addition to conserved amino acid sequences, they also share a common structure containing two RecA-like motifs involved in ATP binding and hydrolysis and nucleic acid binding and unwinding. Unwinding is facilitated 作者: 推遲 時(shí)間: 2025-3-22 02:28
Structure and Mechanisms of SF2 DNA Helicases,ons that constitute these processes. Many of these machines use single-stranded nucleic acids as templates, and their actions are often regulated by the participation of nucleic acids in multimeric structures and macromolecular assemblies that restrict access to chemical information. Superfamily II 作者: adhesive 時(shí)間: 2025-3-22 06:09 作者: 易受刺激 時(shí)間: 2025-3-22 12:43 作者: 上下倒置 時(shí)間: 2025-3-22 16:32 作者: 上下倒置 時(shí)間: 2025-3-22 18:51 作者: Bravado 時(shí)間: 2025-3-22 21:45
RecQ Helicases: Conserved Guardians of Genomic Integrity,RecQ family members have been identified: BLM, WRN, RECQ4, RECQ1 and RECQ5. Defects in three of these give rise to Bloom’s syndrome (BLM), Werner’s syndrome (WRN) and Rothmund–Thomson/RAPADILINO/Baller–Gerold (RECQ4) syndromes. These syndromes are characterised by cancer predisposition and/or premat作者: 代替 時(shí)間: 2025-3-23 03:07 作者: 人類學(xué)家 時(shí)間: 2025-3-23 08:12 作者: 范例 時(shí)間: 2025-3-23 11:10 作者: 頌揚(yáng)本人 時(shí)間: 2025-3-23 14:08
The FtsK Family of DNA Pumps, one cell compartment to another in eubacteria. In the first section of this chapter, we address a list of the cellular functions of the different members of the FtsK family that have been so far studied. Soon after their discovery, interest for the FstK proteins spread because of their unique bioch作者: transdermal 時(shí)間: 2025-3-23 18:48
ATP-Dependent Chromatin Remodeling,cleosomes and higher order chromatin structures. In order to overcome the barrier presented by chromatin structures to the protein machinery carrying out these processes, the cell relies on a class of enzymes called chromatin remodeling complexes which catalyze ATP-dependent restructuring and reposi作者: Accolade 時(shí)間: 2025-3-23 22:49 作者: 事物的方面 時(shí)間: 2025-3-24 03:09 作者: Graduated 時(shí)間: 2025-3-24 06:36
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/d/image/260148.jpg作者: LEVY 時(shí)間: 2025-3-24 10:55
978-1-4899-9851-4The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines作者: 排斥 時(shí)間: 2025-3-24 17:08 作者: Synapse 時(shí)間: 2025-3-24 22:45 作者: laparoscopy 時(shí)間: 2025-3-25 03:01 作者: Picks-Disease 時(shí)間: 2025-3-25 04:14 作者: 祖先 時(shí)間: 2025-3-25 08:24 作者: modifier 時(shí)間: 2025-3-25 12:54
https://doi.org/10.1007/978-3-8348-8620-0ons in human helicase genes are responsible for a variety of genetic disorders and are associated with tumorigenesis. A number of missense mutations in human helicase genes are linked to chromosomal instability diseases characterized by age-related disease or associated with cancer, providing incent作者: EWE 時(shí)間: 2025-3-25 18:34
https://doi.org/10.1007/978-3-8348-8620-0unmet clinical need for improved herpes antivirals. The successful compounds, acyclovir; penciclovir and their orally bioavailable prodrugs valaciclovir and famciclovir, ultimately block virus replication by inhibiting virus-specific DNA-polymerase. The helicase–primase (HP) complex offers a distinc作者: 保存 時(shí)間: 2025-3-25 20:23 作者: 未成熟 時(shí)間: 2025-3-26 02:14 作者: Decongestant 時(shí)間: 2025-3-26 05:15
https://doi.org/10.1007/978-3-658-27654-6integrity of the DNA. Helicases often play a central role in these repair pathways and have shown to be essential for diverse tasks within these mechanisms. In prokaryotic nucleotide excision repair (NER) for example the two helicases UvrB and UvrD assume vastly different functions. While UvrB is in作者: Venules 時(shí)間: 2025-3-26 11:22
https://doi.org/10.1007/978-3-658-27654-6ands. A more encompassing taxonomy that captures alternative enzymatic roles has defined helicases as a sub-class of molecular motors that move directionally and processively along nucleic acids, the so-called “translocases”. However, even this definition may be limiting in capturing the full scope 作者: 詞匯表 時(shí)間: 2025-3-26 13:11 作者: Hyperlipidemia 時(shí)間: 2025-3-26 19:13 作者: 積極詞匯 時(shí)間: 2025-3-26 23:02 作者: 盤旋 時(shí)間: 2025-3-27 03:56
Book 2013icases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies?the editors?aim to provide a unified view on how helicases function in the cell, are regulated in r作者: 斥責(zé) 時(shí)間: 2025-3-27 07:57 作者: 增強(qiáng) 時(shí)間: 2025-3-27 12:41 作者: 老巫婆 時(shí)間: 2025-3-27 14:40 作者: 恃強(qiáng)凌弱 時(shí)間: 2025-3-27 20:24
https://doi.org/10.1007/978-3-8348-8620-0g strand maturation and termination of replication all depend on helicases. Moreover, if disaster strikes and a replication fork breaks down then reloading of the replication machinery is effected by helicases, at least in bacteria. This chapter describes how helicases function in these multiple ste作者: Counteract 時(shí)間: 2025-3-27 22:14 作者: 水槽 時(shí)間: 2025-3-28 02:53
https://doi.org/10.1007/978-3-8348-8620-0--resistance among mutants already shows subtle differences between compounds in this respect. The impact of resistance on the drug development in the clinic will also be considered. Finally, herpesvirus latency remains as the most important barrier to a therapeutic cure. Whether or not helicase pri作者: 規(guī)章 時(shí)間: 2025-3-28 09:12
https://doi.org/10.1007/978-3-658-27654-6 outcomes are dependent upon these helicase enzymes. Since mutations in some of these helicases lead to cancer predisposition in humans and mice, studies on them have clear relevance to human health and disease.作者: 協(xié)迫 時(shí)間: 2025-3-28 11:28 作者: Colonnade 時(shí)間: 2025-3-28 16:17
https://doi.org/10.1007/978-3-658-27654-6ly of RNA helicases and with a model bacterial system, the ATP-dependent Type III restriction-modification enzymes. Further examples are discussed and illustrate the wide-ranging examples of molecular switches in genome metabolism.作者: 偽造者 時(shí)間: 2025-3-28 20:27
,Tiefgaragen, Parkh?user, Rampen,branes. The different activities required for the oriented transport of DNA across cell compartments are achieved by three separate modules within the FtsK proteins: a DNA translocation module, an orientation module and an anchoring module. In the second part of this chapter, we review the structura作者: AWE 時(shí)間: 2025-3-29 01:45
,Tiefgaragen, Parkh?user, Rampen,operate as histone octamer-anchored directional DNA translocases in order to disrupt DNA–histone interactions and catalyze nucleosome sliding. Remodeling mechanisms are family-specific and depend on factors such as how the enzyme engages with nucleosomal and linker DNA, features of DNA loop intermed作者: Affiliation 時(shí)間: 2025-3-29 05:15 作者: 不安 時(shí)間: 2025-3-29 09:01 作者: Forsake 時(shí)間: 2025-3-29 12:27 作者: mastopexy 時(shí)間: 2025-3-29 16:53 作者: Cpap155 時(shí)間: 2025-3-29 23:30 作者: 大都市 時(shí)間: 2025-3-30 03:22 作者: 不適當(dāng) 時(shí)間: 2025-3-30 04:53
DNA Helicases in NER, BER, and MMR,) UvrD again plays a central role. The different tasks of this protein in the different repair pathways highlight the importance of regulative protein–protein interactions to fine-tune its helicase activity. In other DNA repair pathways the role of the helicases involved is sometimes not as well cha作者: Medicare 時(shí)間: 2025-3-30 09:04
Roles for Helicases as ATP-Dependent Molecular Switches,ly of RNA helicases and with a model bacterial system, the ATP-dependent Type III restriction-modification enzymes. Further examples are discussed and illustrate the wide-ranging examples of molecular switches in genome metabolism.
