標(biāo)題: Titlebook: DNA Damage and Repair; Volume 2: DNA Repair Jac A. Nickoloff,Merl F. Hoekstra Book 1998 Springer Science+Business Media New York 1998 Activ [打印本頁] 作者: Addendum 時間: 2025-3-21 18:48
書目名稱DNA Damage and Repair影響因子(影響力)
書目名稱DNA Damage and Repair影響因子(影響力)學(xué)科排名
書目名稱DNA Damage and Repair網(wǎng)絡(luò)公開度
書目名稱DNA Damage and Repair網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱DNA Damage and Repair被引頻次
書目名稱DNA Damage and Repair被引頻次學(xué)科排名
書目名稱DNA Damage and Repair年度引用
書目名稱DNA Damage and Repair年度引用學(xué)科排名
書目名稱DNA Damage and Repair讀者反饋
書目名稱DNA Damage and Repair讀者反饋學(xué)科排名
作者: 天然熱噴泉 時間: 2025-3-21 22:41 作者: DEAF 時間: 2025-3-22 03:46 作者: 不能平靜 時間: 2025-3-22 06:51
Nature of Lesions Formed by Ionizing Radiation,e the source of higher-level damage (killing, mutation, transformation). Of course, the damage that is produced initially by radiation is subject to enzymatic repair, and hence, to assess the ability of a cell to repair the change, it is important to know the identities of the types of damage. Produ作者: 尊重 時間: 2025-3-22 11:27 作者: Vasoconstrictor 時間: 2025-3-22 13:18
Biochemistry of Mammalian DNA Mismatch Repair,ative errors and to protect their DNA from various types of damage .. Mismatch repair systems enhance the fidelity of DNA replication by correcting replicative errors skipped by the DNA polymerase during editing. Mutants defective in mismatch repair enzymes are marked by genome instability and/or mu作者: Vasoconstrictor 時間: 2025-3-22 17:23 作者: helper-T-cells 時間: 2025-3-22 22:23
Role of HMG and Other Proteins in Recognition of Cisplatin DNA Damage, of DNA damage. Presumably, damage recognition is mediated by specific damage-recognition proteins (DRPs), which recognize particular types of DNA lesions and/or specific DNA conformations resulting from adduct formation, such as that following binding of .-diaminedichloroplatinum (II) (cisplatin or作者: NUL 時間: 2025-3-23 04:54
TFIIH,iscovery that one of its subunits was XP-B (ERCC3), a protein known to be involved in nucleotide excision repair (NER; . Chapter 18), put it at the focus of both transcription and DNA repair fields. Further studies in humans and yeast have shown that additional subunits of TFIIH, including XP-D, p62作者: 執(zhí)拗 時間: 2025-3-23 08:04
Mammalian DNA Repair and the Cellular DNA Polymerases,NA, damaged DNA sites must be repaired, and organisms have several DNA repair pathways that are vital in maintaining genome stability. Each individual DNA repair pathway (i.e., error-free repair, base excision repair, nucleotide excision repair, and so forth) is generally similar throughout nature, 作者: 即席演說 時間: 2025-3-23 10:51
Cellular Functions of Mammalian DNA Ligases,ent, such as ionizing radiation, or as a consequence of DNA repair proteins recognizing and excising DNA damage. Thus, the majority of DNA repair mechanisms, including recombinational repair pathways, share a common essential step, phosphodiester bond formation, that restores the integrity of the DN作者: nonsensical 時間: 2025-3-23 15:55
Modulations in Chromatin Structure During DNA Damage Formation and DNA Repair, dynamic structure of chromatin. Understanding the modulation of DNA damage and repair in chromatin, as well as the modulation of chromatin structure by DNA damage and its repair processing, is necessary for understanding the fate of potential mutagenic and carcinogenic lesions in DNA. The central i作者: prostate-gland 時間: 2025-3-23 19:59
Transcriptional Responses to Damage Created by Ionizing Radiation, living cells. IR causes a spectrum of DNA lesions .,including DNA single-strand breaks (SSBs), double-strand breaks (DSBs), DNA—protein crosslinks (intra- and interstrand), and apurinic/apyrimidinic sites (. Chapter 5). The extent of DSBs correlates well with lethality following IR .. IR also damag作者: 能夠支付 時間: 2025-3-24 01:47
Posttranslational Mechanisms Leading to Mammalian Gene Activation in Response to Genotoxic Stress,lar responses occur in unicellular (. Chapters 7 and 18 in vol. 1) and multicellular eukaryotes. In mammalian cells, changes in gene expression are initiated and signaled primarily through posttranslational modifications of key regulatory molecules. Almost immediately on exposing cells to genotoxic 作者: Inordinate 時間: 2025-3-24 03:02
Mechanisms for DNA Double-Strand Break Repair in Eukaryotes,mes, cell death, or cancer. Eukaryotic cells have evolved specific mechanisms for repairing DSBs by either homologous recombination (HR) or nonhomologous recombination (NHR) pathways. This chapter will summarize recent progress in understanding these pathways in eukaryotes. Of particular interest is作者: genuine 時間: 2025-3-24 07:48
Cellular Functions of Mammalian DNA Ligases,anisms, including recombinational repair pathways, share a common essential step, phosphodiester bond formation, that restores the integrity of the DNA substrate molecule(s). In addition, DNA-joining events are required to link together the Okazaki fragments generated during lagging strand DNA synthesis.作者: aggravate 時間: 2025-3-24 12:23 作者: 虛構(gòu)的東西 時間: 2025-3-24 17:47
Mechanisms for DNA Double-Strand Break Repair in Eukaryotes,ous recombination (NHR) pathways. This chapter will summarize recent progress in understanding these pathways in eukaryotes. Of particular interest is the surprising discovery that the nonhomologous pathway shares at least four gene products with V(D)J recombination, a site-specific recombination pathway that generates immunological diversity.作者: 自愛 時間: 2025-3-24 19:11 作者: 思鄉(xiāng)病 時間: 2025-3-25 00:43
coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.978-1-4757-5015-7978-1-59259-455-9作者: chronicle 時間: 2025-3-25 03:21 作者: GLOSS 時間: 2025-3-25 07:37
Archaeoastronomy in the Roman Worldbioassay system through either a mitogenic or mutagenic mechanism ., most of the known potent carcinogens are strong mutagens, and it is these genotoxic carcinogens that are the subject of this chapter.作者: Redundant 時間: 2025-3-25 12:59
https://doi.org/10.1007/978-3-319-21885-4rder to repair, recover, and survive, mammalian cells must first recognize this DNA or membrane damage. Otherwise, the consequences of DNA damage tolerance have been shown to lead to increased rates of mutation and ultimately carcinogenesis, as observed in DNA mismatch repair-deficient cells ..作者: 切掉 時間: 2025-3-25 16:57
https://doi.org/10.1007/978-3-319-21885-4on appears to account for most changes in gene expression, changes in mRNA . or in protein stability (e.g., p53) also can contribute to the changes in protein levels that occur in response to genotoxic stress.作者: 落葉劑 時間: 2025-3-25 22:19
Exogenous Carcinogen-DNA Adducts and Their Repair in Mammalian Cells,bioassay system through either a mitogenic or mutagenic mechanism ., most of the known potent carcinogens are strong mutagens, and it is these genotoxic carcinogens that are the subject of this chapter.作者: fixed-joint 時間: 2025-3-26 02:15 作者: perjury 時間: 2025-3-26 07:44 作者: Mendicant 時間: 2025-3-26 08:34 作者: Neonatal 時間: 2025-3-26 15:02
Role of HMG and Other Proteins in Recognition of Cisplatin DNA Damage, CDDP) to DNA. Once bound to DNA, DRPs are likely to have a major influence on the subsequent processing of specific types of DNA damage. For example, DRPs may influence the kinetics of repair of particular DNA abducts and, hence, determine the physiological response of cells to specific DNA-damaging agents.作者: Forsake 時間: 2025-3-26 17:09
Long-Term Human–Environment Relationsrmed is a potent mutagenic substrate for DNA synthesis, since it can be incorporated opposite adenine as well as cytosine in DNA, at almost equal efficiencies .. In this case, both types of transversions, A-T to C-G and G-C to T-A, would be induced ..作者: 態(tài)學(xué) 時間: 2025-3-26 23:30
Long-Term Human–Environment Relationsnetic diversification .. Mismatch repair is best understood in . (. Chapter 11 in vol. 1). . mutants defective in repair have been isolated and the repair enzymes have been purified and characterized in vitro. A considerable amount of information is also available about mismatch repair in the yeast . (. Chapter 19 in vol. 1).作者: 放縱 時間: 2025-3-27 01:52
The Pottery Pathway at the Ceremonial Center for both functions. This chapter summarizes recent data, which with the identification of the cyclin-dependent kinase (Cdk7) as another integral component of TFIIH, extends the possible roles of the complex to cell-cycle regulation and point to a crucial role for the complex in the overall function of the cell.作者: obviate 時間: 2025-3-27 08:55
Mammalian Enzymes for Preventing Mutations Caused by Oxidation of Guanine Nucleotides,rmed is a potent mutagenic substrate for DNA synthesis, since it can be incorporated opposite adenine as well as cytosine in DNA, at almost equal efficiencies .. In this case, both types of transversions, A-T to C-G and G-C to T-A, would be induced ..作者: Blemish 時間: 2025-3-27 09:51 作者: Angioplasty 時間: 2025-3-27 16:34
TFIIH, for both functions. This chapter summarizes recent data, which with the identification of the cyclin-dependent kinase (Cdk7) as another integral component of TFIIH, extends the possible roles of the complex to cell-cycle regulation and point to a crucial role for the complex in the overall function of the cell.作者: deceive 時間: 2025-3-27 21:31 作者: cauda-equina 時間: 2025-3-28 00:17
Augusto S. Auler,Luís Beethoven Pilóa(chǎn)nisms, including recombinational repair pathways, share a common essential step, phosphodiester bond formation, that restores the integrity of the DNA substrate molecule(s). In addition, DNA-joining events are required to link together the Okazaki fragments generated during lagging strand DNA synthesis.作者: GENRE 時間: 2025-3-28 04:20 作者: Bronchial-Tubes 時間: 2025-3-28 08:46
https://doi.org/10.1007/978-3-319-21885-4ous recombination (NHR) pathways. This chapter will summarize recent progress in understanding these pathways in eukaryotes. Of particular interest is the surprising discovery that the nonhomologous pathway shares at least four gene products with V(D)J recombination, a site-specific recombination pathway that generates immunological diversity.作者: FLAG 時間: 2025-3-28 14:27 作者: 貿(mào)易 時間: 2025-3-28 15:16
Archaeoastronomy in the Roman WorldPhotoreactivation was discovered by chance in 1949 during a study of UV-induced mutagenesis when unexpected results were obtained that could be attributed to a greatly enhanced survival of UV-irradiated . conidia after illumination with visible light .. A similar phenomenon was found for the survival of UV-irradiated bacteriophages in ..作者: 公豬 時間: 2025-3-28 22:13
DNA Photolyases,Photoreactivation was discovered by chance in 1949 during a study of UV-induced mutagenesis when unexpected results were obtained that could be attributed to a greatly enhanced survival of UV-irradiated . conidia after illumination with visible light .. A similar phenomenon was found for the survival of UV-irradiated bacteriophages in ..作者: vibrant 時間: 2025-3-29 02:57 作者: Engulf 時間: 2025-3-29 06:33 作者: 血友病 時間: 2025-3-29 07:36
Archaeoastronomy in the Roman Worldance An essential set of repair pathways must be operative in all living systems to maintain genomic stability in the face of the natural endogenous threats to DNA as well as those resulting from cellular exposures to radiation and chemicals in the external environment. The intrinsic chemical labili作者: entreat 時間: 2025-3-29 13:15 作者: 多節(jié) 時間: 2025-3-29 16:22
Archaeoastronomy in the Roman Worldtional Agency for Research on Cancer, 60 or more of these chemicals are probably carcinogenic in humans .. Despite recent exciting discoveries of inherited susceptibilities to cancer, such as the association of certain colon cancers with a deficiency in mismatch repair (.; . Chapter 20), Doll has ar作者: 可觸知 時間: 2025-3-29 23:41 作者: dialect 時間: 2025-3-30 03:42 作者: 打谷工具 時間: 2025-3-30 08:04 作者: 腐敗 時間: 2025-3-30 11:08
https://doi.org/10.1007/978-3-319-31400-6nd . were shown to possess a postreplicative mismatch correction system whose function involved the resynthesis of long tracts of DNA, up to several kilobases in length .. In addition, . was shown by Lieb . to possess an additional, very short-patch (VSP) mismatch repair pathway, which is dedicated 作者: landmark 時間: 2025-3-30 16:25 作者: Spongy-Bone 時間: 2025-3-30 16:51 作者: Insul島 時間: 2025-3-30 22:32
The Pottery Pathway at the Ceremonial CenterNA, damaged DNA sites must be repaired, and organisms have several DNA repair pathways that are vital in maintaining genome stability. Each individual DNA repair pathway (i.e., error-free repair, base excision repair, nucleotide excision repair, and so forth) is generally similar throughout nature, 作者: indigenous 時間: 2025-3-31 04:00
Augusto S. Auler,Luís Beethoven Pilóent, such as ionizing radiation, or as a consequence of DNA repair proteins recognizing and excising DNA damage. Thus, the majority of DNA repair mechanisms, including recombinational repair pathways, share a common essential step, phosphodiester bond formation, that restores the integrity of the DN作者: AUGER 時間: 2025-3-31 07:22 作者: CHURL 時間: 2025-3-31 12:02
https://doi.org/10.1007/978-3-319-21885-4 living cells. IR causes a spectrum of DNA lesions .,including DNA single-strand breaks (SSBs), double-strand breaks (DSBs), DNA—protein crosslinks (intra- and interstrand), and apurinic/apyrimidinic sites (. Chapter 5). The extent of DSBs correlates well with lethality following IR .. IR also damag作者: Pepsin 時間: 2025-3-31 17:25 作者: stressors 時間: 2025-3-31 20:00
https://doi.org/10.1007/978-3-319-21885-4mes, cell death, or cancer. Eukaryotic cells have evolved specific mechanisms for repairing DSBs by either homologous recombination (HR) or nonhomologous recombination (NHR) pathways. This chapter will summarize recent progress in understanding these pathways in eukaryotes. Of particular interest is作者: CYT 時間: 2025-3-31 23:47
