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標題: Titlebook: Cytokines: Interleukins and Their Receptors; Razelle Kurzrock,Moshe Talpaz Book 1995 Kluwer Academic Publishers 1995 cytokine.cytokines.on [打印本頁]

作者: Covenant    時間: 2025-3-21 18:53
書目名稱Cytokines: Interleukins and Their Receptors影響因子(影響力)




書目名稱Cytokines: Interleukins and Their Receptors影響因子(影響力)學科排名




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書目名稱Cytokines: Interleukins and Their Receptors網絡公開度學科排名




書目名稱Cytokines: Interleukins and Their Receptors被引頻次




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作者: Vulnerable    時間: 2025-3-22 00:07

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https://doi.org/10.1007/978-3-476-03745-9e of mast cells to IL-3 or IL-4. It is now known that all these activities are mediated by IL-10. This chapter will summarize our present knowledge of IL-10 structure, its relationship to its viral counterpart BCRF1, and the various functional activities described for these factors.
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0927-3042 mal and abnormal human development. Today, it isapparent that cytokines orchestrate growth from the early embryonicstage to maturity and are responsible for the normal function ofvirtually every organ system. Furthermore, virtually all diseasestates have been associated, at least in part, with cytok
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https://doi.org/10.1007/978-3-476-03745-9eral leukocyte chemotactic factors such as C5a, leukotriene B., and bacteria-derived formyl peptide have been long described [2]. However, these factors can induce Chemotaxis of any type of leukocytes, thus suggesting the existence of a cell-type-specific leukocyte chemotactic factor(s) in addition to these nonspecific ones.
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Book 1995normal human development. Today, it isapparent that cytokines orchestrate growth from the early embryonicstage to maturity and are responsible for the normal function ofvirtually every organ system. Furthermore, virtually all diseasestates have been associated, at least in part, with cytokineaberrat
作者: JAUNT    時間: 2025-3-23 09:54
https://doi.org/10.1007/978-3-476-03745-9me receptor, and possess identical biological activities [21,22]. In contrast to the agonist activities of IL-1α and IL-1β, IL-1RA is a specific antagonist of IL-1 that acts by blocking the binding of IL-1 to its cell surface receptors [23–25].
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Interleukin-1 and its inhibitors: Implications for disease biology and therapy,me receptor, and possess identical biological activities [21,22]. In contrast to the agonist activities of IL-1α and IL-1β, IL-1RA is a specific antagonist of IL-1 that acts by blocking the binding of IL-1 to its cell surface receptors [23–25].
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作者: 煩擾    時間: 2025-3-24 09:28
Interleukin-7 and lymphopoiesis: Biological and clinical implications,ion, IL-7 appears to hold promise in enhancing antimicrobial responses. This chapter describes in detail the current status of IL-7 as a regulator of lymphopoiesis and effector cell function, and the potential therapeutic implications of the IL-7 preclinical studies performed in mice.
作者: 心神不寧    時間: 2025-3-24 14:04
Interleukin-3 and its receptor,em and to direct it to specific targets [1], Among these, IL-3 (or multi-CSF) is known as a pleiotropic cytokine with a broad spectrum of target cells and functions. This article summarizes relevant data about this molecule that has been the topic of several recent review articles [2–5].
作者: GRAVE    時間: 2025-3-24 17:25
Interleukin-6: A comprehensive review,ent progress in the analysis of IL-6-activated signal transduction mechanisms. IL-6 expression in different disease states has been demonstrated; IL-6 may be involved as a mediator in certain aspects in the pathogenesis of infection, autoimmunity, and malignancy.
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作者: 無關緊要    時間: 2025-3-25 00:50
Control of thrombocytopoiesis: Current state of the art,elet production.[1] The cells of the megakaryocyte lineage include the primitive, actively proliferating progenitors cells as well as mature post-mitotic megakaryocytes undergoing maturational development (Figure 1). The complex nature of this developmental hierarchy is underscored by the wide varie
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Interleukin-2: Its rationale and role in the treatment of patients with cancer,ne marrow-derived cell suspensions [1]. They further characterized the cells proliferating in response to this growth factor as T cells [2]. Helper and cytotoxic T cells expanded in this T-cell growth factor maintained their in vitro and in vivo activity [3–6]. The gene for this T-cell growth factor
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Structure and function of interleukin-4 and its receptor, T lymphocytes, mast cells, and basophils [1–5]. Consistent with the pleiotropic nature of this molecule, the receptors for IL-4 have been identified on many different cell types, including hematopoietic and non-hematopoietic cells (see reveiws [6,7]). Recent studies have identified a couple of nove
作者: 殺人    時間: 2025-3-25 20:37
Interleukin-5: An overview,n/IgE complex or calcium ionophores [1,2]. The study of murine (m) IL-5 originated in the search for T-cell-replacing factor (TRF), which induces 2,4-dinitrophenyl (DNP)-primed B cells to differentiate into anti-DNP IgG-producing cells [3], as well as the proliferation of BCL. B-cell tumor cells int
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A novel leukocyte chemotactic and activating cytokine, interleukin-8 (IL-8),iltration into a site of inflammation. Limited types of leukocytes infiltrate, depending upon the type, degree, and timing of tissue injuries [1]. Several leukocyte chemotactic factors such as C5a, leukotriene B., and bacteria-derived formyl peptide have been long described [2]. However, these facto
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Interleukin-10 (IL-10),cells. IL-10 was detected independently in several laboratories. Fiorentino et al. [1] described a cytokine secreted by ‘type 2’ murine helper T-cell clones which inhibited cytokine production by ‘type 1’ helper T-cell clones. It was therefore designated as cytokine synthesis inhibitory factor (CSIF
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Interleukin-11 (IL-11) and its receptor: Biology and potential clinical applications in thrombocytos. It is believed that the steady-state equilibrium of hematopoiesis results from the interplay between these stromal cells and stem/progenitor cells through cell-cell contact and local production of cytokines. We have analyzed the growth-factor production of a primate stromal fibroblast cell line,
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Book 1995spects. .Cytokines: Interleukins andtheir. .Receptors. should be of interest to a wide variety ofresearchers including clinical hematologists, oncologists,immunologists, in addition to medical and PhD students and researcherswith an interest in cytokines. .
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0927-3042 clinical aspects. .Cytokines: Interleukins andtheir. .Receptors. should be of interest to a wide variety ofresearchers including clinical hematologists, oncologists,immunologists, in addition to medical and PhD students and researcherswith an interest in cytokines. .978-1-4612-8528-1978-1-4613-1241-3Series ISSN 0927-3042 Series E-ISSN 2509-8497
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Kai Brodersen,Bernhard Zimmermannserved. Thus cytokines can act at all positions of the hematopoietic family tree, and the response can differ from proliferation and differentiation of progenitor cells to functional activation of mature cells. Under physiological conditions, during constitutive hematopoiesis, the regulatory cytokin
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Antik?rper in der Krebsbek?mpfung T and NK cells [2,6], and to facilitate cytolytic T-lymphocyte (CTL) responses [7,8]. All of these activities are shared by IL-12 with other interleukins such as IL-2. However, IL-12 has more recently been found to play a critical and unique role in promoting T.1-type cytokine responses [9,10], the
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New Antimalarial Trioxanes and Endoperoxides cytokines described previously, namely IL-4 and IL-2, respectively [2–4]. This coincidence of function is paralleled by these cytokines sharing at least some of their receptor components [5–7], and it is now clear that this mechanism is repetitively utilized in the immune system [8]. A full underst
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Interleukin-5: An overview,ated and provide a convenient biological assay for IL-5 [12]. In humans, human (h) IL-5 inducs the production of eosinophils from bone marrow progenitors and works for survival and priming of eosinophils in vitro [11]. hIL-5 expression was observed in many diseases with eosinophilia, suggesting that
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Interleukin-12: A pivotal regulator of cell-mediated immunity, T and NK cells [2,6], and to facilitate cytolytic T-lymphocyte (CTL) responses [7,8]. All of these activities are shared by IL-12 with other interleukins such as IL-2. However, IL-12 has more recently been found to play a critical and unique role in promoting T.1-type cytokine responses [9,10], the
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Interleukin-9: Structural characteristics and biologic properties,ecificity for certain T-Helper clones [1]. In the presence of IL-9 containing supernatants, stable T-cell lines could be derived in the absence of feeder cells and antigen. The growth factor present in such supernatants was further purified, its corresponding cDNA was cloned, and provisionally designated P40 [2].
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https://doi.org/10.1007/978-1-4613-1241-3cytokine; cytokines; oncology
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https://doi.org/10.1007/978-3-476-03745-9factor. Two distinct IL-1 polypeptides termed IL-1α and IL-1β, have been identified and are known to be the products of distinct genes. IL-1α and IL-1β are members of a family of cytokines that also includes the IL-1 receptor antagonist protein (IL-1RA) [1,2]. Although found predominantly in monocyt
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https://doi.org/10.1007/978-3-476-03745-9 T lymphocytes, mast cells, and basophils [1–5]. Consistent with the pleiotropic nature of this molecule, the receptors for IL-4 have been identified on many different cell types, including hematopoietic and non-hematopoietic cells (see reveiws [6,7]). Recent studies have identified a couple of nove




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