標題: Titlebook: Cytokine Knockouts; Giamila Fantuzzi Book 2003Latest edition Springer Science+Business Media New York 2003 Chemokine.Immune System.autoimm [打印本頁] 作者: ALLY 時間: 2025-3-21 18:33
書目名稱Cytokine Knockouts影響因子(影響力)
書目名稱Cytokine Knockouts影響因子(影響力)學科排名
書目名稱Cytokine Knockouts網(wǎng)絡公開度
書目名稱Cytokine Knockouts網(wǎng)絡公開度學科排名
書目名稱Cytokine Knockouts被引頻次
書目名稱Cytokine Knockouts被引頻次學科排名
書目名稱Cytokine Knockouts年度引用
書目名稱Cytokine Knockouts年度引用學科排名
書目名稱Cytokine Knockouts讀者反饋
書目名稱Cytokine Knockouts讀者反饋學科排名
作者: Lyme-disease 時間: 2025-3-21 23:25
Molecular Basis for Binding Multiple Cytokines by γcr γc-dependent cytokine receptors. Molecular modeling in conjunction with site-directed mutagenesis of γc indicates that a common mechanism is responsible for the ability of γc to bind multiple cytokines. This notion is related to instances in which mutations in the extracytoplasmic region of γc resulted in X-SCID.作者: fleeting 時間: 2025-3-22 01:44
Book 2003Latest editionbout cytokine biology and physiology. For those not familiar with cytokine research, the authors present a critical discussion of the advantages and disadvantages of using cytokine knockout mice in various fields of research.作者: 異端 時間: 2025-3-22 06:14
ed, along with much important information about cytokine biology and physiology. For those not familiar with cytokine research, the authors present a critical discussion of the advantages and disadvantages of using cytokine knockout mice in various fields of research.978-1-61737-415-9978-1-59259-405-4作者: 思考才皺眉 時間: 2025-3-22 12:05
Global Maternal and Child Healthby these studies belong almost exclusively to the innate immunity compartment. This strengthens the view that disturbed recruitment of innate immunity mechanisms is at least as important in the pathogenesis of the autoimmune disease process as the antigen-specific reaction towards self.作者: TAG 時間: 2025-3-22 15:14 作者: TAG 時間: 2025-3-22 20:05 作者: 閑聊 時間: 2025-3-22 22:02
The Use of Cytokine Knockouts in Animal Models of Autoimmune Diseaseby these studies belong almost exclusively to the innate immunity compartment. This strengthens the view that disturbed recruitment of innate immunity mechanisms is at least as important in the pathogenesis of the autoimmune disease process as the antigen-specific reaction towards self.作者: DEBT 時間: 2025-3-23 01:58
A Unique Role for IL-2 in Self-Toleranceection of autoreactive CD4 T-cells is being discussed. In conclusion, it has become clear that while redundant as a T-cell growth factor, IL-2 serves a unique role as a negative regulator of the immune system with an essential task in maintaining self tolerance.作者: accomplishment 時間: 2025-3-23 09:11 作者: 遭遇 時間: 2025-3-23 10:09
Braucht die Medizin eine Anthropologie?e the pathogenic role of cytokines using knockout mice, in an attempt to relate the results obtained with models of LPS jitoxicity and those using other models of autoimmune- or chemically induced inflammation.作者: 范例 時間: 2025-3-23 15:16
https://doi.org/10.1007/978-3-030-84514-8ies for cancer treatment. This chapter reviews important insights, provided by the role of cytokine knockout mice, into the role of Thl cytokines in regulation of development and progression of neoplasia, and their potential use as cancer therapeutics.作者: insincerity 時間: 2025-3-23 19:40
https://doi.org/10.1007/978-3-030-84514-8echnology, we were limited to focusing on the use of genetically modified animals in two areas, namely, fever as a model of infection and stroke following middle cerebral artery occlusion as an approach to study brain injury and inflammation.作者: 玉米棒子 時間: 2025-3-23 23:43 作者: 領導權(quán) 時間: 2025-3-24 03:50 作者: JOT 時間: 2025-3-24 08:33
Cytokine Knockouts in Inflammatione the pathogenic role of cytokines using knockout mice, in an attempt to relate the results obtained with models of LPS jitoxicity and those using other models of autoimmune- or chemically induced inflammation.作者: infringe 時間: 2025-3-24 11:56
The Use of Cytokine Knockout Mice in Cancer Researchies for cancer treatment. This chapter reviews important insights, provided by the role of cytokine knockout mice, into the role of Thl cytokines in regulation of development and progression of neoplasia, and their potential use as cancer therapeutics.作者: 忘恩負義的人 時間: 2025-3-24 18:14 作者: 侵略者 時間: 2025-3-24 22:38 作者: excursion 時間: 2025-3-25 01:48 作者: Arroyo 時間: 2025-3-25 04:00 作者: DRAFT 時間: 2025-3-25 09:30
8), Giamila Fantuzzi and a panel of experts have generated completely new chapters to reflect the use of many novel mouse strains and the hundreds of recent studies on cytokine physiology. Comprehensive reviews of the numerous often-surprising results obtained using cytokine knockout mice are provid作者: Ablation 時間: 2025-3-25 14:28
Giamila FantuzziIncludes supplementary material: 作者: 不透明 時間: 2025-3-25 17:54
Contemporary Immunologyhttp://image.papertrans.cn/d/image/242630.jpg作者: Abduct 時間: 2025-3-25 22:04 作者: superfluous 時間: 2025-3-26 03:24
978-1-61737-415-9Springer Science+Business Media New York 2003作者: 未開化 時間: 2025-3-26 05:38
Braucht die Medizin eine Anthropologie?nes, has led to an evolution of the concept of inflammation. Although IL-1 receptor antagonist and TNF inhibitors are approved for the therapy of rheumatoid arthritis, the role of IL-1 and TNF in inflammation was discovered by studying their effect in models of endotoxin [lipopolysaccharide (LPS)] s作者: COUCH 時間: 2025-3-26 09:38
Anthropologie und Ethik der Biomedizinennial issue of how cytokines function to benefit human evolution. Usually duplication or redundancy of a gene suggests that it functions to assist the survival of the species. In the case of the proinflammatory cytokines, their role in the survival of the host is less clear since this class of cyto作者: fledged 時間: 2025-3-26 14:05 作者: Embolic-Stroke 時間: 2025-3-26 17:35
https://doi.org/10.1007/978-3-030-84514-8 adaptive responses to tumors, infectious agents, and in the bone marrow transplant setting. The use of appropriate cytokine knockout mice provides an invaluable approach to understanding the key elements of response and nonresponse in various settings. This mechanistic insight is vital for developi作者: MOCK 時間: 2025-3-27 00:12
https://doi.org/10.1007/978-3-030-84514-8ogy research. This is a fast-growing area that is expanding dramatically as genetically modified animals for cytokines, their receptors, or signalling components become available. We have focused primarily on the best-known cytokines (IL-1, IL-6, TNF-α, IL-10 & IL-4) simply to highlight the contribu作者: 連接 時間: 2025-3-27 03:50
Culture, Cancer, and Communication in Italy.). The original identification of IL-1 as an endogenous pyrogen, lymphocyte-activating factor, hemopoietin-1, and osteoclast-activating factor, serves to demonstrate its pleiotropic activity (.). IL-1, produced by cell types such as macrophages, monocytes, and synovial lining cells, induces inflamm作者: 綠州 時間: 2025-3-27 05:39 作者: 顯赫的人 時間: 2025-3-27 09:32 作者: chiropractor 時間: 2025-3-27 15:03
About the Origins of this Volumeal killer (NK) cell development and are responsible for X-linked severe combined immunodeficiency disease (X-SCID). Considerable attention has been paid to how the lack of γc expression and signaling results in failed lymphocyte development. However, γc is also an essential ligand binding subunit fo作者: kindred 時間: 2025-3-27 18:20 作者: 采納 時間: 2025-3-28 01:43 作者: 我們的面粉 時間: 2025-3-28 04:04
Robert L. Rubinstein,J. Keith,D. Wielandnd blood in response to allergic and parasitic stimuli. IL-5 also plays a central role in regulating baseline blood and tissue eosinophil numbers but is not essential for eosinophil development or migration. Thus, eosinophil accumulation into allergic tissues should not be viewed as a process that i作者: gruelling 時間: 2025-3-28 06:58 作者: 悶熱 時間: 2025-3-28 10:25 作者: CRAFT 時間: 2025-3-28 17:49 作者: 得體 時間: 2025-3-28 21:59 作者: 很像弓] 時間: 2025-3-29 02:51 作者: 悠然 時間: 2025-3-29 06:51
The Use of Cytokine Knockouts to Study Host Defense Against Infectionbute to host defense mechanisms using the very same molecular and cellular pathways involved in chronic inflammation, tissue destruction, and tissue remodeling. How does one reconcile the existence of two opposing outcomes for the host—one clearly not in the interest of survival and another vital to作者: 哥哥噴涌而出 時間: 2025-3-29 09:30
IL-1 Receptor Antagonist-Deficient Mice The disturbed balance of activity of the IL-1 system, even though it is part of the innate immune system, appears to feed into the activity of the adaptive immune response, creating autoimmune conditions. Investigating the mechanism for this specificity may well yield important insights into the na作者: Commission 時間: 2025-3-29 13:27 作者: GROUP 時間: 2025-3-29 18:46
Role of IL-5 in Immune and Pathological Responses in the Mouse pathways coexist in many disease and immune responses. Importantly, studies in IL-5. mice are disclosing an important role for this cytokine in the regulation of immune responses by modulating lymphocyte function.作者: 想象 時間: 2025-3-29 20:14
IL-10 and IL-2 Knockout Mices of CD4+ and CD8+ T cells, as well as B220+ B cells, suggesting that both T and B cells are spontaneously activated in the colonic immune response. As in the IL-10 deficient mouse, disease in the IL-2-deficient mouse is dependent upon the presence of luminal microflora and is modulated by the genet作者: nurture 時間: 2025-3-30 01:05 作者: Confidential 時間: 2025-3-30 05:33
IL-13 and Double IL-4/IL-13 Knockout Miceeneration of AHR. The roles of IL-4 and IL-13 have obvious implications for the development of therapeutic strategies for cytokine/anti-cytokine modulation of immune reactions. The use of conventional transgenic mice and gene knockout mice has already provided important functional information regard作者: CERE 時間: 2025-3-30 11:08
IL-15address specific roles for IL-15 in the generation and function of immune cells. Wherever applicable, comparisons are provided to studies in IL-15Ra deficient mice..Analysis of IL-15 and IL-15Ra deficient mice has shown that IL-15 is a crucial factor for the maturation, survival, and activation of N作者: 埋伏 時間: 2025-3-30 15:58
Anthropologie und Ethik der Biomedizinbute to host defense mechanisms using the very same molecular and cellular pathways involved in chronic inflammation, tissue destruction, and tissue remodeling. How does one reconcile the existence of two opposing outcomes for the host—one clearly not in the interest of survival and another vital to作者: 配置 時間: 2025-3-30 20:13 作者: 毀壞 時間: 2025-3-30 21:35
https://doi.org/10.1007/978-94-009-2031-6s chapter we review the generation and characterization of mice deficient in each of these cytokines. These studies have delineated essential roles for the molecules in hematopoiesis, immunity, and pulmonary homeostasis.作者: Amnesty 時間: 2025-3-31 04:23 作者: CROW 時間: 2025-3-31 07:10
