標(biāo)題: Titlebook: Cystogenesis; Jong Hoon Park,Curie Ahn Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Natu [打印本頁] 作者: 出租 時間: 2025-3-21 17:25
書目名稱Cystogenesis影響因子(影響力)
書目名稱Cystogenesis影響因子(影響力)學(xué)科排名
書目名稱Cystogenesis網(wǎng)絡(luò)公開度
書目名稱Cystogenesis網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cystogenesis被引頻次
書目名稱Cystogenesis被引頻次學(xué)科排名
書目名稱Cystogenesis年度引用
書目名稱Cystogenesis年度引用學(xué)科排名
書目名稱Cystogenesis讀者反饋
書目名稱Cystogenesis讀者反饋學(xué)科排名
作者: collateral 時間: 2025-3-21 23:03 作者: Friction 時間: 2025-3-22 04:26
Cell Proliferation and Apoptosis in ADPKDisruption of either . or ., the main causative genes of ADPKD, intracellular calcium homeostasis and cAMP accumulation are disrupted, which in turn leads to altered signaling in the pathways that regulate cell proliferation. These dysregulations finally stimulate the development of fluid-filled cyst作者: 乞討 時間: 2025-3-22 07:37
Inflammation and Fibrosis in ADPKDtant pathway related to this disease. However, studies on the interactions of inflammation and fibrosis with polycystic kidney disease have been limited. Inflammation is one of the protective systems involved in the response to foreign molecules. In PKD, it was reported that the activity of signalin作者: 籠子 時間: 2025-3-22 10:36
Functional Study of the Primary Cilia in ADPKDays such as Wnt, PDGFRα, Hh, and mechanosignaling are localized to the membrane of the primary cilium. In the kidney, primary cilia extend from the cell membrane to the lumen of renal tubules to respond to fluidic stress. Recent studies have indicated that the disruption of ciliary proteins includin作者: dowagers-hump 時間: 2025-3-22 13:43
Epigenetic Regulation in Cystogenesismodification, and gene regulation by microRNAs are well-known epigenetic modulations that are closely associated with several cellular processes and diverse disease states, such as cancers, even under precancerous conditions. More recently, several studies have indicated that epigenetic changes may 作者: dowagers-hump 時間: 2025-3-22 21:07 作者: occult 時間: 2025-3-23 00:01
Diagnostic Evaluation as a Biomarker in Patients with ADPKD declines over a long period of time, the evaluation of treatment effects in ADPKD has been very difficult. Therefore, there has been a great interest to find out the “better” surrogate marker or biomarker which reflects disease progression. Biomarkers in ADPKD should have three clinical implication作者: Mercurial 時間: 2025-3-23 03:50
Clinical Trials and a View Toward the Future of ADPKDies, autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disease, and is characterized by the progressive enlargement of bilateral renal cysts, resulting in end-stage kidney failure. Progress in genetics and molecular pathobiology has enabled the development of therape作者: 擁護(hù) 時間: 2025-3-23 05:32 作者: famine 時間: 2025-3-23 09:47 作者: 拋物線 時間: 2025-3-23 17:12 作者: Occipital-Lobe 時間: 2025-3-23 21:40 作者: 攀登 時間: 2025-3-24 01:56 作者: DAMN 時間: 2025-3-24 05:45
https://doi.org/10.1007/978-3-642-91395-2 (PKD), suggesting that the malformation or absence of primary cilia is a driving force of the onset of PKD. Therefore, in this chapter, the renal cystogenesis mechanism induced by cilia defects and pathogenic ciliary proteins associated with PKD development will be described.作者: 潔凈 時間: 2025-3-24 07:19 作者: 正式通知 時間: 2025-3-24 14:44
Anleitung zur Untersuchung der Lebensmittelter from the treatment, and (3) they should be easy to evaluate short-term outcome after treatment, which will demonstrate hard outcome. Herein, we will discuss currently available surrogate biomarkers including the volume of total kidney and urinary molecular markers.作者: conscribe 時間: 2025-3-24 18:16 作者: 向外 時間: 2025-3-24 20:00 作者: Paradox 時間: 2025-3-25 02:10
Cell Proliferation and Apoptosis in ADPKDce between cell proliferation and apoptosis seems to contribute to cyst growth and renal tissue remodeling in ADPKD. In this section, the mechanisms through which cell proliferation and apoptosis are involved in disease progression, and further, how those signaling pathways impinge on each other in ADPKD will be discussed.作者: adequate-intake 時間: 2025-3-25 04:46
Functional Study of the Primary Cilia in ADPKD (PKD), suggesting that the malformation or absence of primary cilia is a driving force of the onset of PKD. Therefore, in this chapter, the renal cystogenesis mechanism induced by cilia defects and pathogenic ciliary proteins associated with PKD development will be described.作者: 本土 時間: 2025-3-25 08:08 作者: 清真寺 時間: 2025-3-25 15:35
Diagnostic Evaluation as a Biomarker in Patients with ADPKDter from the treatment, and (3) they should be easy to evaluate short-term outcome after treatment, which will demonstrate hard outcome. Herein, we will discuss currently available surrogate biomarkers including the volume of total kidney and urinary molecular markers.作者: Bravura 時間: 2025-3-25 16:48 作者: 職業(yè) 時間: 2025-3-25 23:57
Validation of Effective Therapeutic Targets for ADPKD Using Animal Modelsches using PKD animal models would shed light on the development of potential therapeutic strategies for PKD. Here, we provide an update on the current evidence obtained by the in vivo evaluation of PKD therapeutic candidates and discuss the effect of therapeutic targets.作者: IRATE 時間: 2025-3-26 00:44
https://doi.org/10.1007/978-3-642-91395-2 pathways, such as the negative growth regulation, G protein activation, and canonical and non-canonical Wnt pathways. According to the “second hit” model, an additional somatic mutation results in the expansion of cyst growth. In this chapter we discuss the genetic mechanisms and signaling pathways involved in ADPKD.作者: 沉著 時間: 2025-3-26 05:42
0065-2598 rials in ADPKD research.Opens the door for the development oAutosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) 作者: Neonatal 時間: 2025-3-26 11:29
G. H. Simmons M.D.,M. Fislibein M.D.ches using PKD animal models would shed light on the development of potential therapeutic strategies for PKD. Here, we provide an update on the current evidence obtained by the in vivo evaluation of PKD therapeutic candidates and discuss the effect of therapeutic targets.作者: 惡臭 時間: 2025-3-26 16:01 作者: BOGUS 時間: 2025-3-26 18:37 作者: 饑荒 時間: 2025-3-27 00:20
978-981-10-9511-5The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor作者: CREST 時間: 2025-3-27 04:10 作者: extinct 時間: 2025-3-27 09:17 作者: overbearing 時間: 2025-3-27 09:59
https://doi.org/10.1007/978-3-642-91395-2isruption of either . or ., the main causative genes of ADPKD, intracellular calcium homeostasis and cAMP accumulation are disrupted, which in turn leads to altered signaling in the pathways that regulate cell proliferation. These dysregulations finally stimulate the development of fluid-filled cyst作者: 出汗 時間: 2025-3-27 13:44 作者: 先行 時間: 2025-3-27 21:07
https://doi.org/10.1007/978-3-642-91395-2ays such as Wnt, PDGFRα, Hh, and mechanosignaling are localized to the membrane of the primary cilium. In the kidney, primary cilia extend from the cell membrane to the lumen of renal tubules to respond to fluidic stress. Recent studies have indicated that the disruption of ciliary proteins includin作者: doxazosin 時間: 2025-3-28 01:04 作者: Scintillations 時間: 2025-3-28 05:05 作者: 磨坊 時間: 2025-3-28 09:12
Anleitung zur Untersuchung der Lebensmittel declines over a long period of time, the evaluation of treatment effects in ADPKD has been very difficult. Therefore, there has been a great interest to find out the “better” surrogate marker or biomarker which reflects disease progression. Biomarkers in ADPKD should have three clinical implication作者: Mingle 時間: 2025-3-28 11:17 作者: 消滅 時間: 2025-3-28 14:37
Jong Hoon Park,Curie AhnPresents key challenges in the study of Autosomal dominant polycystic kidney disease (ADPKD).Covers basic cellular mechanisms and clinical trials in ADPKD research.Opens the door for the development o作者: 過度 時間: 2025-3-28 20:09
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/d/image/242603.jpg作者: miscreant 時間: 2025-3-29 00:44
Cystogenesis978-981-10-2041-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: CLIFF 時間: 2025-3-29 07:02
