作者: 死貓他燒焦 時(shí)間: 2025-3-21 23:25
,Laboratory Diagnosis of Cushing’s Disease and Syndrome,ish those who may have suggestive signs and symptoms, but may prove to be eucorticoid, from those patients who actually have increased corticosteroid production. In the latter group, it is further necessary to distinguish patients with Cushing’s disease from those with either adrenal or ectopic ACTH-producing tumors.作者: 填料 時(shí)間: 2025-3-22 01:52 作者: fabricate 時(shí)間: 2025-3-22 05:47
A Commentary on the Poems of Thomas Hardyish those who may have suggestive signs and symptoms, but may prove to be eucorticoid, from those patients who actually have increased corticosteroid production. In the latter group, it is further necessary to distinguish patients with Cushing’s disease from those with either adrenal or ectopic ACTH-producing tumors.作者: 似少年 時(shí)間: 2025-3-22 10:41 作者: 引導(dǎo) 時(shí)間: 2025-3-22 13:59
Michael Robartes and the Dancermulates the adrenal cortex in vertebrate animals and man. The N-terminal 24 amino acids are identical in all species studied. Minor species differences in amino acid composition occur in the 25–39 portion of the molecule. On a molar basis, the 1–24 amino acid sequence of the ACTH molecule possesses 作者: 引導(dǎo) 時(shí)間: 2025-3-22 19:36
https://doi.org/10.1007/978-1-349-00163-7structural sequences for these actions and the mechanisms by which they produce their effects. Most of the structure-function relationships have dealt with the steroidogenic activity of ACTH (Hofmann 1974; Schwyzer 1977). The concept has evolved that there are sequences which comprise the “active” o作者: Plaque 時(shí)間: 2025-3-23 01:13 作者: 構(gòu)成 時(shí)間: 2025-3-23 02:50
https://doi.org/10.1007/978-1-349-00163-7of ACTH is the predominant form identified in the pituitary, except for a variable fraction (previously termed big ACTH) eluting in the void volume, which represents approximately 15 %–25 % of the total ACTH content (Gewirtz and Yalow 1974; Orth and Nicholson 1977). Since at the time of these studie作者: 六個(gè)才偏離 時(shí)間: 2025-3-23 07:06
https://doi.org/10.1007/978-1-349-00163-7me that will enable clinical distinctions to be made among the various subgroups. For this reason, greatest emphasis in this chapter will be placed on the pathophysiology of Cushing’s disease, since the clinical findings associated with this condition are seen in virtually all other causes of Cushin作者: lacrimal-gland 時(shí)間: 2025-3-23 12:57
A Commentary on the Poems of Thomas Hardyish those who may have suggestive signs and symptoms, but may prove to be eucorticoid, from those patients who actually have increased corticosteroid production. In the latter group, it is further necessary to distinguish patients with Cushing’s disease from those with either adrenal or ectopic ACTH作者: peptic-ulcer 時(shí)間: 2025-3-23 15:13
https://doi.org/10.1057/9780230598904ociated atrophy of the contralateral adrenal, patients will require postoperative replacement therapy for a variable time period (3–18 months) until normal adrenocortical function is regained. Cortisol replacement therapy should be maintained at a sufficient dose to avoid symptoms of hypoadrenalism 作者: Classify 時(shí)間: 2025-3-23 19:42 作者: allude 時(shí)間: 2025-3-23 23:03 作者: 要控制 時(shí)間: 2025-3-24 03:32 作者: 莊嚴(yán) 時(shí)間: 2025-3-24 06:59
Book 1982cal use. It is perhaps difficult to believe that as recently as 35-40 years ago, before cortisone and cortisol were clinically available, the surgical removal of a benign adrenal cortical tumor in patients with Cushing‘s syndrome was associated with a prohibitive postoperative mortality rate. Within作者: 空中 時(shí)間: 2025-3-24 14:17
ACTH Action,nces smaller than 1–18 exhibit markedly diminished activity. The C-terminal 25–39 appears to influence the degradation of the molecule, so that human 1–39 has a longer duration of action than 1–24 (Baumann and Felber, 1976).作者: electrolyte 時(shí)間: 2025-3-24 18:35
0077-1015 e surgical removal of a benign adrenal cortical tumor in patients with Cushing‘s syndrome was associated with a prohibitive postoperative mortality rate. Within978-3-642-81661-1978-3-642-81659-8Series ISSN 0077-1015 作者: Wallow 時(shí)間: 2025-3-24 21:58 作者: 無(wú)能力之人 時(shí)間: 2025-3-25 02:05 作者: 易于出錯(cuò) 時(shí)間: 2025-3-25 07:08 作者: Rinne-Test 時(shí)間: 2025-3-25 10:29 作者: hypnogram 時(shí)間: 2025-3-25 12:57 作者: amenity 時(shí)間: 2025-3-25 18:34
https://doi.org/10.1057/9780230598904recovery at the pituitary level takes a longer time than does that of adrenal responsiveness to ACTH, and the excess Cortisol secretion engendered by such ACTH administration might further delay pituitary recovery.作者: 即席演說(shuō) 時(shí)間: 2025-3-25 20:36
,Treatment of Cushing’s Disease and Syndrome,recovery at the pituitary level takes a longer time than does that of adrenal responsiveness to ACTH, and the excess Cortisol secretion engendered by such ACTH administration might further delay pituitary recovery.作者: BROTH 時(shí)間: 2025-3-26 03:25
0077-1015 ry. We owe these advances to the felicitous cooperative efforts of the clinical investigator and the biochemist. Three centuries elapsed between the first recorded anatomical descrip- tion of the adrenals and the demonstration by Dr. Addison in the mid-nineteenth century of the fatal results of the 作者: 震驚 時(shí)間: 2025-3-26 06:58 作者: 直覺(jué)好 時(shí)間: 2025-3-26 08:29
,Brief Introduction to Cushing’s Syndrome and Disease,tain.” Cushing’s description of the disease included all of those physical features which today we recognize as being classical. It is also of interest that a follow-up of the patient over a period of 22 years following the onset of the disease noted her to be in “reasonably good health, though some of the stigmata of her malady still persist.”作者: Palate 時(shí)間: 2025-3-26 15:22
Physiology of Regulation of ACTH Secretion,biological steroidogenic activity equivalent to that of the ACTH. molecule. There is a marked loss of steroidogenic potency with sequences smaller than ACTH.. The duration of action is also diminished by deletion of COOH terminal sequences (Schwyzer 1964).作者: 意見(jiàn)一致 時(shí)間: 2025-3-26 17:27
Actions of Adrenocortical Hormones,corticoid actions (Baxter and Forsham 1972). It is believed that both the catabolic and anabolic responses seen with corticosteroid administration reflect the expression of similar mechanisms in different tissues (Leung and Munck 1975).作者: DOTE 時(shí)間: 2025-3-27 00:10 作者: pericardium 時(shí)間: 2025-3-27 02:24
Book 1982 these advances to the felicitous cooperative efforts of the clinical investigator and the biochemist. Three centuries elapsed between the first recorded anatomical descrip- tion of the adrenals and the demonstration by Dr. Addison in the mid-nineteenth century of the fatal results of the destructio作者: 充氣女 時(shí)間: 2025-3-27 09:17 作者: 一回合 時(shí)間: 2025-3-27 13:23
Physiology of Regulation of ACTH Secretion,mulates the adrenal cortex in vertebrate animals and man. The N-terminal 24 amino acids are identical in all species studied. Minor species differences in amino acid composition occur in the 25–39 portion of the molecule. On a molar basis, the 1–24 amino acid sequence of the ACTH molecule possesses 作者: BAIT 時(shí)間: 2025-3-27 14:04 作者: PLAYS 時(shí)間: 2025-3-27 19:34
Actions of Adrenocortical Hormones,icoid hormones., since, in cases of Cushing’s disease and syndrome, glucocorticoid concentrations may rise well into the pharmacological range (Table 4.1). These hormones affect virtually all body tissues. In recent years, investigators have sought to establish a common basic mechanism for all gluco作者: 形上升才刺激 時(shí)間: 2025-3-28 00:10 作者: CLOWN 時(shí)間: 2025-3-28 03:41 作者: dictator 時(shí)間: 2025-3-28 08:18
,Laboratory Diagnosis of Cushing’s Disease and Syndrome,ish those who may have suggestive signs and symptoms, but may prove to be eucorticoid, from those patients who actually have increased corticosteroid production. In the latter group, it is further necessary to distinguish patients with Cushing’s disease from those with either adrenal or ectopic ACTH作者: Etymology 時(shí)間: 2025-3-28 13:49
,Treatment of Cushing’s Disease and Syndrome,ociated atrophy of the contralateral adrenal, patients will require postoperative replacement therapy for a variable time period (3–18 months) until normal adrenocortical function is regained. Cortisol replacement therapy should be maintained at a sufficient dose to avoid symptoms of hypoadrenalism 作者: burnish 時(shí)間: 2025-3-28 17:21
DNA, RNA e sintesi proteica muscolare,ticolari formazioni dette cromosomi; essi rappresentano, pertanto, le molecole che contengono tutte le informazioni necessarie per la crescita, la specializzazione e la vita di ciascuna cellula. Oltre al DNA contenuto nel nucleo, ogni individuo possiede anche del DNA mitocondriale che, a differenza 作者: invert 時(shí)間: 2025-3-28 21:34 作者: 我沒(méi)有命令 時(shí)間: 2025-3-28 23:19
Zwischenfazit: Herausforderungen und unbefriedigende L?sungsvorschl?ger diese Radikall?sung noch das Zurückziehen in das eigene Schneckenhaus und die Besch?ftigung mit sich selber stellen einen gangbaren Weg dar. Es bedarf einfach nur einer neuen, klar definierten Form der Zusammenarbeit zwischen den Akteuren des Personalbereichs und den Führungskr?ften aus den andere
