標題: Titlebook: Current Advances in Osteosarcoma; Eugenie S. Kleinerman, M.D. Book 20141st edition Springer Nature Switzerland AG 2014 bone cancer.cancer. [打印本頁] 作者: nourish 時間: 2025-3-21 19:35
書目名稱Current Advances in Osteosarcoma影響因子(影響力)
書目名稱Current Advances in Osteosarcoma影響因子(影響力)學(xué)科排名
書目名稱Current Advances in Osteosarcoma網(wǎng)絡(luò)公開度
書目名稱Current Advances in Osteosarcoma網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Current Advances in Osteosarcoma被引頻次
書目名稱Current Advances in Osteosarcoma被引頻次學(xué)科排名
書目名稱Current Advances in Osteosarcoma年度引用
書目名稱Current Advances in Osteosarcoma年度引用學(xué)科排名
書目名稱Current Advances in Osteosarcoma讀者反饋
書目名稱Current Advances in Osteosarcoma讀者反饋學(xué)科排名
作者: 奴才 時間: 2025-3-21 22:19
Wnt Signaling in Osteosarcomaonal co-activator β-catenin, which ultimately controls key developmental gene expressions. Given the central role of this mediator, inhibition of Wnt/β-catenin signaling has been investigated as a potential strategy for cancer control. In OS, several secreted protein families modulate the Wnt/β-cate作者: 極小 時間: 2025-3-22 01:45
Receptor Tyrosine Kinases in Osteosarcoma: Not Just the Usual Suspectse then validated using independent validation experiments. From these results, we identified four RTKs (Axl, EphB2, FGFR2, and Ret) that have not been previously studied in osteosarcoma and provide targets for the development of novel therapeutics.作者: 慢慢沖刷 時間: 2025-3-22 05:56 作者: 奴才 時間: 2025-3-22 09:47
Developmental Pathways Hijacked by OsteosarcomaThis pathway also helps regulate expression of the mature osteoblast protein osteocalcin. YAP also regulates expression of MT1-MMP, a membrane-bound matrix metalloprotease responsible for remodeling the extracellular matrix surrounding the osteoblasts. YAP, in turn, can be regulated by the ERBB fami作者: 政府 時間: 2025-3-22 15:22 作者: 政府 時間: 2025-3-22 19:00
Role of Ezrin in Osteosarcoma Metastasis protein that associated with OS and other cancers. Ezrin is the prototypical ERM (Ezrin/Radixin/Moesin) protein family member. ERMs function as linker proteins connecting the actin cytoskeleton and the plasma membrane. Since our initial identification of ezrin in pediatric sarcoma, an increasing un作者: 輕快來事 時間: 2025-3-22 22:31 作者: 獨白 時間: 2025-3-23 02:14 作者: 催眠藥 時間: 2025-3-23 08:48
Using Canine Osteosarcoma as a Model to Assess Efficacy of Novel Therapies: Can Old Dogs Teach Us Nethout chemotherapy that could not be done in humans with osteosarcoma due to ethical concerns. This chapter will focus on the novel therapies in the dog that have been reported or are in veterinary clinical trials at the author’s institution. It is hoped that collaboration between veterinary oncolog作者: 發(fā)微光 時間: 2025-3-23 13:41
Oncolytic Viruses for Potential Osteosarcoma Therapy specific and replication competent viruses. Osteosarcoma is a challenging malignancy to identify novel targets for therapy due to its complex genetic make-up. Oncolytic virotherapy may be a promising approach as a novel therapeutic, not dependent on consistent expression of a single target. In this作者: 貪婪地吃 時間: 2025-3-23 17:49 作者: insurrection 時間: 2025-3-23 20:34 作者: hidebound 時間: 2025-3-24 00:08 作者: arrogant 時間: 2025-3-24 06:11
Worship Spaces: 1001–2000 Seatse then validated using independent validation experiments. From these results, we identified four RTKs (Axl, EphB2, FGFR2, and Ret) that have not been previously studied in osteosarcoma and provide targets for the development of novel therapeutics.作者: NATTY 時間: 2025-3-24 07:27
https://doi.org/10.1007/978-1-4939-3097-5ls and pericytes, are the major source of Notch activation in osteosarcoma tumors in vivo and in patients. As a result, Notch pathway expression is not expected to be uniform across a tumor but likely to be highest in those areas immediately adjacent to blood vessels. Therapeutic targeting of the No作者: 大火 時間: 2025-3-24 12:54 作者: 瑣事 時間: 2025-3-24 17:59
Jarno Drost,Benedetta Artegiani,Hans Clevers sensitivity to GCB in LM7 cells. By contrast, inhibiting autophagy in K7M3 cells decreased GCB sensitivity. Defining the role autophagy plays in chemotherapy response in different tumor types has become of greater importance in order to identify the best suitable therapeutic approach. In this chapt作者: 不可接觸 時間: 2025-3-24 22:41 作者: dysphagia 時間: 2025-3-25 01:04 作者: 喪失 時間: 2025-3-25 03:43
Jagdeep Kaur,Dilip Shah,John Fellersof zebrafish based cancer research, such as robotic high-throughput multicolor injection systems and advanced imaging methods are discussed. Furthermore, various use of zebrafish embryos for screening drug regimens by combinations of chemotherapy, novel drug deliverers, and immune system modulators 作者: kyphoplasty 時間: 2025-3-25 10:45
Biolistic Transformation of Wheatthout chemotherapy that could not be done in humans with osteosarcoma due to ethical concerns. This chapter will focus on the novel therapies in the dog that have been reported or are in veterinary clinical trials at the author’s institution. It is hoped that collaboration between veterinary oncolog作者: 合唱隊 時間: 2025-3-25 15:43 作者: Synapse 時間: 2025-3-25 17:26 作者: 神圣將軍 時間: 2025-3-25 21:05
Book 20141st editionlogical characteristics that have been uncovered in the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and it is also the most common histological form of bone cancer.?It accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children a作者: 憤慨一下 時間: 2025-3-26 00:14 作者: 不如樂死去 時間: 2025-3-26 06:52 作者: 溝通 時間: 2025-3-26 10:48 作者: magnate 時間: 2025-3-26 13:40 作者: 費解 時間: 2025-3-26 20:44
HER-2 Involvement in Osteosarcomadescribed. This pathway has also been explored as a therapeutic target with at least one study of trastuzumab for the treatment of osteosarcoma completed. Other studies utilizing alternative approaches to target the HER-2 receptor for the treatment of osteosarcoma have been considered.作者: 流動性 時間: 2025-3-26 22:07 作者: 打算 時間: 2025-3-27 02:29
MicroRNAs in Osteosarcomagenesisable malignancy with virtually no apparent precursor neoplasms that are partway along a disease path toward OS? With this conundrum as a backdrop, the discovery of every new native molecule with power to impact a cell’s biology is usually quickly followed by a search to see if this type of molecule contains the key to unlock OS biology.作者: Permanent 時間: 2025-3-27 06:17 作者: hegemony 時間: 2025-3-27 12:04 作者: Salivary-Gland 時間: 2025-3-27 16:45 作者: crockery 時間: 2025-3-27 19:50
Christin Gasch,Klaus Pantel,Sabine Riethdorf century. The first agents that held promise were doxorubicin and high-dose methotrexate with leucovorin (citrovorin factor) in the mid-1970s. Since then, other agents that can eliminate or cause regression of tumor have been discovered: cis-diamminedichloroplatinum II (cisplatin) and the oxazaphosp作者: 民間傳說 時間: 2025-3-27 23:48
Worship Spaces: 1001–2000 Seatsnt metastasis. Despite current multidisciplinary treatments, there has not been a drastic change in overall prognosis within the last two decades. With current treatments, 60–70 % of patients with localized disease survive. Given a propensity of Wnt signaling to control multiple cellular processes, 作者: 制定法律 時間: 2025-3-28 03:49 作者: 意見一致 時間: 2025-3-28 06:52
https://doi.org/10.1007/978-1-4939-3097-5th in malignant cells and nonmalignant components of tumors, make it more difficult to define Notch as simply an oncogene or a tumor suppressor. The cell-autonomous behaviors caused by Notch pathway manipulation may vary between cell lines but can include changes in proliferation, migration, invasiv作者: Veneer 時間: 2025-3-28 10:46 作者: Heretical 時間: 2025-3-28 18:10 作者: 誘使 時間: 2025-3-28 20:53 作者: Urgency 時間: 2025-3-29 02:18 作者: Lumbar-Stenosis 時間: 2025-3-29 03:04
Jarno Drost,Benedetta Artegiani,Hans Clevers of epidermal growth factor receptor pathway to breast cancer and the finding that HER-2 was expressed in a proportion of osteosarcoma, it was reasonable to investigate this pathway further. Investigations of HER-2 in osteosarcoma have led to the publication of numerous conflicting reports with rega作者: 混雜人 時間: 2025-3-29 07:46
Assessment of Aggressiveness of , on Wheat pediatric sarcoma patients such as those with osteosarcoma (OS), despite successful management of the primary tumor through multimodality approaches, the development of metastases, commonly to the lungs, is the cause of death. Significant improvements in long-term outcome for these patients have no作者: 最有利 時間: 2025-3-29 14:38 作者: 諂媚于性 時間: 2025-3-29 16:11
Jagdeep Kaur,Dilip Shah,John Fellers, zebrafish has become a comprehensive model for cancer research. Hence, zebrafish embryos and full-grown fish have been instrumental for studies of leukemia, melanoma, pancreatic cancer, bone tumors, and other malignancies. Although because of its similarities to human osteogenesis zebrafish appear作者: Catheter 時間: 2025-3-29 20:57
Biolistic Transformation of Wheatdog also shares many of our diseases including cancer such as osteosarcoma. Like the human, osteosarcoma is the most common bone malignancy of the dog and death from pulmonary metastasis is the most common outcome. The incidence of this spontaneous bone neoplasm occurs ten times more frequently that作者: affect 時間: 2025-3-30 00:25
James M. Humber,Robert F. Almedered at a rapid pace finally making its way into clinical trials. A large number of both wild-type and genetically altered viruses with a preferential replication-competency for tumor cells have been studied in tissue cultures, animal models and in humans, with an ever increasing repertoire of new vir作者: 陰郁 時間: 2025-3-30 07:08
https://doi.org/10.1007/978-1-59259-451-1sease specific proteins expressed on tumor vasculature have been identified by in vivo phage display technology and the diversity of the tumor-associated vasculature has provided the basis for the development of targeted therapeutics. Investigators recently screened a phage display library in a huma作者: Venules 時間: 2025-3-30 10:00 作者: Peculate 時間: 2025-3-30 12:25 作者: 明智的人 時間: 2025-3-30 19:28
https://doi.org/10.1007/978-3-319-04843-7bone cancer; cancer; metastasis; osteosarcoma; pediatric cancer作者: 蹣跚 時間: 2025-3-30 23:12 作者: padding 時間: 2025-3-31 01:54 作者: monochromatic 時間: 2025-3-31 06:06 作者: indubitable 時間: 2025-3-31 11:08 作者: 容易生皺紋 時間: 2025-3-31 17:01
Understanding the Role of Notch in Osteosarcomath in malignant cells and nonmalignant components of tumors, make it more difficult to define Notch as simply an oncogene or a tumor suppressor. The cell-autonomous behaviors caused by Notch pathway manipulation may vary between cell lines but can include changes in proliferation, migration, invasiv作者: 外貌 時間: 2025-3-31 20:12
Developmental Pathways Hijacked by Osteosarcomathe normal counterpart’s development can aid in understanding the malignant state. This is certainly true for osteosarcoma and the normal developmental pathways that guide osteoblast development that are changed in the genesis of osteogenic sarcoma. A carefully regulated crescendo–decrescendo expres作者: morale 時間: 2025-4-1 01:10
