作者: IRATE 時(shí)間: 2025-3-21 20:34 作者: 高原 時(shí)間: 2025-3-22 03:12
Controlled Nanoscale Motion978-3-540-49522-2Series ISSN 0075-8450 Series E-ISSN 1616-6361 作者: Jacket 時(shí)間: 2025-3-22 05:16 作者: macrophage 時(shí)間: 2025-3-22 09:58 作者: 輪流 時(shí)間: 2025-3-22 14:46
https://doi.org/10.1007/978-3-662-42945-7addressed in this chapter is how does the fundamental chemistry of ATP hydrolysis in- fluence the observed organization of linear molecular motors seen today with a focus on myosin. This chapter is written to ask in simple terms what can be gained by reconsidering the chemistry of ATP hydrolysis.作者: 輪流 時(shí)間: 2025-3-22 17:50 作者: congenial 時(shí)間: 2025-3-23 00:06
https://doi.org/10.1007/978-3-662-42945-7s between cell body and synapse that takes place within extremely long, narrow axons requires motor-driven active transport along polarized microtubules. We summarize some imaging and theoretical modeling strategies recently developed to better understand axonal transport and neuronal function. Our 作者: 蔑視 時(shí)間: 2025-3-23 03:21 作者: TOXIN 時(shí)間: 2025-3-23 08:34 作者: Anguish 時(shí)間: 2025-3-23 11:28
https://doi.org/10.1007/978-3-662-42945-7 tens of microns) in various intra- and intercellular transport processes. These ubiquitous structures are often formed from flat membranes by highly localized forces generated by either the pulling of motor proteins or the pushing of polymerizing cytoskeletal filaments. In this chapter we give an o作者: 和諧 時(shí)間: 2025-3-23 16:33 作者: Lime石灰 時(shí)間: 2025-3-23 21:25 作者: dermatomyositis 時(shí)間: 2025-3-24 01:53
https://doi.org/10.1007/978-3-662-42945-7om equilibrium, such as a biomolecule stretched irreversibly using optical tweezers. The key to decoding this information resides in the external work, ., performed on the system. I will give a brief summary of three theoretical predictions that relate nonequilibrium statistical fluctuations in . to作者: SEVER 時(shí)間: 2025-3-24 06:06 作者: 枯萎將要 時(shí)間: 2025-3-24 08:46 作者: atopic-rhinitis 時(shí)間: 2025-3-24 13:48 作者: 菊花 時(shí)間: 2025-3-24 15:04
https://doi.org/10.1007/978-3-662-42945-7nto rotation. Rotation may be transmitted via belts or gears, converted into linear motion by various linkages, or used to drive propellers to produce fluid motion. Examples of macroscopic rotors include engines which couple to combustible energy sources, windmills which couple to air flows, and mos作者: 階層 時(shí)間: 2025-3-24 21:09 作者: 知識(shí)分子 時(shí)間: 2025-3-25 01:05 作者: 故意釣到白楊 時(shí)間: 2025-3-25 03:30 作者: 格子架 時(shí)間: 2025-3-25 09:09
https://doi.org/10.1007/978-3-662-42950-1y ordered in the filament lattice of the muscle sarcomere. In contrast to this wellordered structure, most in vitro studies are performed with the contractile proteins in a disordered arrangement. Here we first review the existing in vitro motility assays and then consider how they can be improved b作者: 易彎曲 時(shí)間: 2025-3-25 11:59 作者: Gossamer 時(shí)間: 2025-3-25 18:39 作者: 使增至最大 時(shí)間: 2025-3-25 22:06
Nanodevices for Single Molecule Studies,ile existing technology enables the analysis of a variety of biological systems, new tools are needed for increasing the efficiency of current methods, and for developing new ones altogether. Interest has grown in single molecule analysis for these reasons.作者: Amplify 時(shí)間: 2025-3-26 02:50
https://doi.org/10.1007/978-3-662-42945-7 is a bacterium 1 μm in diameter. It swims in a nutrient medium, counting molecules of interest as it goes along. On the basis of these counts, it accumulates in regions that it deems more favorable. How does nature design, construct, and operate such a nanomachine?作者: headway 時(shí)間: 2025-3-26 08:21 作者: TAIN 時(shí)間: 2025-3-26 10:07 作者: optic-nerve 時(shí)間: 2025-3-26 14:53 作者: Pantry 時(shí)間: 2025-3-26 17:58
F. Holle Prof. Dr.,W. Hart Priv.-Doz. Dr.stinct mechanisms (i) electrostatic interactions, based on asymmetric shape of electrostatic potential inside the pore, and (ii) electro-mechanical gate placed at the entrance of a conical pore, responsive to the external field applied across the membrane. Biosensors consisting of single conical nanotubes are discussed as well.作者: ineffectual 時(shí)間: 2025-3-26 22:55 作者: STING 時(shí)間: 2025-3-27 04:35
Tuning Ion Current Rectification in Synthetic Nanotubes,stinct mechanisms (i) electrostatic interactions, based on asymmetric shape of electrostatic potential inside the pore, and (ii) electro-mechanical gate placed at the entrance of a conical pore, responsive to the external field applied across the membrane. Biosensors consisting of single conical nanotubes are discussed as well.作者: Halfhearted 時(shí)間: 2025-3-27 06:10 作者: WATER 時(shí)間: 2025-3-27 12:27
https://doi.org/10.1007/978-3-662-42945-7verview of the theory of membrane nanotubes, their biological relevance, and the most recent experiments designed for the study of their formation and dynamics. We also discuss the effect of membrane proteins or lipid composition on the shape of the tubes, and the effect of antagonistic motor proteins on tube formation.作者: tattle 時(shí)間: 2025-3-27 17:19
https://doi.org/10.1007/978-3-662-42945-7iated with the mutual relocation of the enzyme relative to the polymer substrate is the most likely source. A comparison between the mechanism underlying the nanoscale motion of enzymes working on polysaccharides, with various known types of energy catalysing the motion is discussed.作者: 正式演說(shuō) 時(shí)間: 2025-3-27 20:09
https://doi.org/10.1007/978-3-662-42945-7tein molecules. This suggests that DNA-based nanodevices powered by DNA-based molecular motors may find application in fields such as chemistry, materials science, and medicine. Here we describe the principles by which the motors that power these devices work and survey the range of devices that have been constructed.作者: Herbivorous 時(shí)間: 2025-3-27 23:40
Studies of DNA-Protein Interactions at the Single Molecule Level with Magnetic Tweezers, DNA’s topology (topoisomerases), unwind it (helicases) or translocate it (FtsK). We will show how the new tools at our disposal can be used to gain an unprecedented description of the binding properties (on and off-times) and the enzymes’ kinetic constants that are often out of reach of more classical, bulk techniques.作者: 清澈 時(shí)間: 2025-3-28 05:06
Membrane Nanotubes,verview of the theory of membrane nanotubes, their biological relevance, and the most recent experiments designed for the study of their formation and dynamics. We also discuss the effect of membrane proteins or lipid composition on the shape of the tubes, and the effect of antagonistic motor proteins on tube formation.作者: Mortal 時(shí)間: 2025-3-28 07:48
Macromolecular Motion at the Nanoscale of Enzymes Working on Polysaccharides,iated with the mutual relocation of the enzyme relative to the polymer substrate is the most likely source. A comparison between the mechanism underlying the nanoscale motion of enzymes working on polysaccharides, with various known types of energy catalysing the motion is discussed.作者: Arthr- 時(shí)間: 2025-3-28 11:45
Using DNA to Power the Nanoworld,tein molecules. This suggests that DNA-based nanodevices powered by DNA-based molecular motors may find application in fields such as chemistry, materials science, and medicine. Here we describe the principles by which the motors that power these devices work and survey the range of devices that have been constructed.作者: 北極人 時(shí)間: 2025-3-28 17:50
Book 2007ol of motion at the nanoscale therefore requires physical understanding and technical approaches that are fundamentally different from those that are successful at the macroscale...This volume provides an introduction to the state-of-the-art of controlled nanoscale motion in biological and artificia作者: enfeeble 時(shí)間: 2025-3-28 19:10
Book 2007of synthetic molecular motors...The chapters in this book are based on selected contributions on the 2005 Nobel Symposium to Controlled Nanoscale Motion and are written by leading experts in their fields..作者: 兩種語(yǔ)言 時(shí)間: 2025-3-28 23:57
0075-8450 brication of synthetic molecular motors...The chapters in this book are based on selected contributions on the 2005 Nobel Symposium to Controlled Nanoscale Motion and are written by leading experts in their fields..978-3-662-50088-0978-3-540-49522-2Series ISSN 0075-8450 Series E-ISSN 1616-6361 作者: inhibit 時(shí)間: 2025-3-29 03:38 作者: 擁擠前 時(shí)間: 2025-3-29 09:54 作者: Resign 時(shí)間: 2025-3-29 13:59 作者: MAIZE 時(shí)間: 2025-3-29 16:05
When is a Distribution Not a Distribution, and Why Would You Care: Single-Molecule Measurements of tutorial on the models we use to think about the physics, the limited and noisy data, and how to squeeze the maximum amount of physics from these data. The second half is about our experiments and results.作者: GRIPE 時(shí)間: 2025-3-29 21:41 作者: 捏造 時(shí)間: 2025-3-30 00:05 作者: 愛(ài)管閑事 時(shí)間: 2025-3-30 06:05 作者: Foolproof 時(shí)間: 2025-3-30 11:32
How Linear Motor Proteins Work,the cytoplasm resembles a gel with a mesh size of approximately 50 nm, which makes the passive transport of organelle-sized particles impossible. For elongated cells such as neurons, even proteins and small metabolites have to be actively transported.作者: synovium 時(shí)間: 2025-3-30 14:02 作者: Cardioplegia 時(shí)間: 2025-3-30 16:41
Artificial Dipolar Molecular Rotors,chapter we discuss the miniaturization of rotary machines all the way to the molecular scale, where chemical groups form the rotary and stationary parts. For a recent review of molecules with rotary and stationary parts see [1].作者: harmony 時(shí)間: 2025-3-31 00:42 作者: 形上升才刺激 時(shí)間: 2025-3-31 01:32
How Linear Motor Proteins Work,ement is not generally associated with plants, cytoplasmic streaming in plant cells can reach velocities greater than 50 μm/s and thus constitutes one of the fastest forms of directed movement. Unicellular eukaryotic organisms and prokaryotes display diverse mechanisms by which they are able to acti作者: Tinea-Capitis 時(shí)間: 2025-3-31 07:02
Axonal Transport: Imaging and Modeling of a Neuronal Process,s between cell body and synapse that takes place within extremely long, narrow axons requires motor-driven active transport along polarized microtubules. We summarize some imaging and theoretical modeling strategies recently developed to better understand axonal transport and neuronal function. Our 作者: 緯線 時(shí)間: 2025-3-31 11:39
Intracellular Transport and Kinesin Superfamily Proteins: Structure, Function and Dynamics,gnificant functions in intracellular transport, which is fundamental for cellular morphogenesis, functioning, and survival. We showed that KIFs not only transport various membranous organelles, proteins complexes and mRNAs fundamental for cellular functions but also play significant roles in higher 作者: grovel 時(shí)間: 2025-3-31 15:01 作者: obstinate 時(shí)間: 2025-3-31 18:27 作者: 協(xié)定 時(shí)間: 2025-3-31 22:38
Macromolecular Motion at the Nanoscale of Enzymes Working on Polysaccharides,oduce oligomers as a result of depolymerisation. Enzyme catalysed polymerisation of polysaccharides may also create motion of entire species (bacteria). The energy balance show the clear role of biochemically accessible energy in most of such examples, whereas in others, conformational changes assoc作者: 讓步 時(shí)間: 2025-4-1 02:28 作者: calorie 時(shí)間: 2025-4-1 08:37 作者: 實(shí)施生效 時(shí)間: 2025-4-1 13:28
When is a Distribution Not a Distribution, and Why Would You Care: Single-Molecule Measurements of sional diffusion of LacI repressor proteins along elongated Lambda DNA using single molecule imaging techniques. We find that (1) LacI diffuses along nonspecific sequences of DNA in the form of 1D Brownian motion; (2) the observed 1D diffusion coefficients D. vary over an unexpectedly large range, f作者: insidious 時(shí)間: 2025-4-1 17:24
