標(biāo)題: Titlebook: Control of Metabolic Processes; Athel Cornish-Bowden,María Luz Cárdenas Book 1990 Springer Science+Business Media New York 1990 Amino acid [打印本頁] 作者: CLAST 時間: 2025-3-21 18:46
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書目名稱Control of Metabolic Processes讀者反饋
書目名稱Control of Metabolic Processes讀者反饋學(xué)科排名
作者: 煩擾 時間: 2025-3-21 21:10 作者: 埋葬 時間: 2025-3-22 02:57 作者: NOMAD 時間: 2025-3-22 07:56 作者: 無效 時間: 2025-3-22 11:49
Peter A. Wieringa,Henk G. Stassenyond the threshold-generating step. Control of flux indeed appears to be distributed over the various steps of a pathway (Kacser & Bums, 1973; Westerhoff ., 1984). The reversible shutting down of the flux above a suprathreshold stimulation should, however, prove a most efficient way of generating sharp transitions under steady-state conditions.作者: 側(cè)面左右 時間: 2025-3-22 15:37 作者: 側(cè)面左右 時間: 2025-3-22 19:54 作者: Afflict 時間: 2025-3-23 01:12
Essentials of Nevanlinna Theory,s. This does not necessarily imply that control analysis is better than the other two theories. It does, however, suggest that control analysis is easier to understand for the mathematically untrained.作者: 混亂生活 時間: 2025-3-23 04:43
David D. Woods,Nadine B. Sarter between 10% and 90% of full activity) if its concentration increases at least three-fold. Even a Hill coefficient as high as 6, rarely seen in nature, would only lower this ratio to two-fold. Furthermore, as flux control coefficients in reality are usually less than unity, the sensitivity of the pathway to the effector is decreased accordingly.作者: defenses 時間: 2025-3-23 08:03
Modern Control Theories: a Consumers’ Tests. This does not necessarily imply that control analysis is better than the other two theories. It does, however, suggest that control analysis is easier to understand for the mathematically untrained.作者: Toxoid-Vaccines 時間: 2025-3-23 11:33
Properties Needed for the Enzymes of an Interconvertible Cascade to Generate a Highly Sensitive Resp between 10% and 90% of full activity) if its concentration increases at least three-fold. Even a Hill coefficient as high as 6, rarely seen in nature, would only lower this ratio to two-fold. Furthermore, as flux control coefficients in reality are usually less than unity, the sensitivity of the pathway to the effector is decreased accordingly.作者: 欺騙世家 時間: 2025-3-23 14:47 作者: SEEK 時間: 2025-3-23 19:31
Recent Studies on Borel Directions,ral metabolic system, though the specific example treated in their paper was a linear pathway. Their methods of deriving expressions for flux control coefficients could be applied to other pathways [for example, a branched pathway: Kacser (1983)1, but on a case by case argument from first principles.作者: Antagonist 時間: 2025-3-24 02:00
History and Original Thoughts on the Control Theoretic Approachhall nevertheless address this history in those terms. Hopefully some grandchildren will be reading too. But let me note at the outset that I am not a scientific historian and that I present this history from a rather personal view.作者: Exonerate 時間: 2025-3-24 02:36
Control Coefficients and the Matrix Methodral metabolic system, though the specific example treated in their paper was a linear pathway. Their methods of deriving expressions for flux control coefficients could be applied to other pathways [for example, a branched pathway: Kacser (1983)1, but on a case by case argument from first principles.作者: indubitable 時間: 2025-3-24 06:31
Book 1990It sets out to present the current state of understanding of the principles governing the way fluxes and concentrations are maintained and controlled in metabolic systems. Although this is a topic that has held the interest of biochemists for many years, it is only quite recently that the methods of作者: LEVY 時間: 2025-3-24 13:48
The Nature and Role of Theory in Metabolic Controlscience. In this introductory chapter, therefore, I plan to discuss these questions, with the hope of providing a context in which the claims of metabolic control theory as a legitimate theory can be discussed. Elsewhere (Cornish-Bowden, 1989) I have discussed the criticisms of metabolic control the作者: overrule 時間: 2025-3-24 15:43 作者: 斷言 時間: 2025-3-24 22:24
Comparison of Accuracy of Alternative Models for Biochemical Pathwaysageau, 1989.), and of the specific operations involved in the execution of an analysis (as described by Savageau in Chapter 4 of this book) all have shown that these three theories are related variants based on the ., even though some of the specific aims and applications of each approach may appear作者: febrile 時間: 2025-3-25 01:49 作者: epicardium 時間: 2025-3-25 03:31
Practical Determination of Control Coefficients in Metabolic Pathwaysddition of enzyme.This is often extremely difficult to achieve. With this regard indirect methods exist by which local properties (elasticity or special elasticity coefficients) are calculated first. Then control coefficients are calculated by using the equations corresponding to the theorems of met作者: 牽索 時間: 2025-3-25 10:36 作者: indemnify 時間: 2025-3-25 13:28
cooperativity. Even those who have become convinced that the classical ideas provide only the starting point for understanding metabolic control have been by no means unanimous in their assess- ment of the direction in which one should advance. In this book we have tried to include all of the current points o978-1-4757-9858-6978-1-4757-9856-2作者: Fortuitous 時間: 2025-3-25 17:55 作者: Isometric 時間: 2025-3-25 22:04
https://doi.org/10.1007/978-3-662-02915-2 the biochemical network in a straightforward fashion. The parameters of the .-system — rate constants and kinetic orders — are readily related to experimental data. The steady-state behaviour is characterized by a set of linear algebraic equations that can be solved symbolically or numerically. The作者: drusen 時間: 2025-3-26 00:48
https://doi.org/10.1007/978-3-662-02915-2ageau, 1989.), and of the specific operations involved in the execution of an analysis (as described by Savageau in Chapter 4 of this book) all have shown that these three theories are related variants based on the ., even though some of the specific aims and applications of each approach may appear作者: 沒收 時間: 2025-3-26 06:11 作者: FLORA 時間: 2025-3-26 09:28 作者: Cerumen 時間: 2025-3-26 16:15 作者: Bouquet 時間: 2025-3-26 20:16
The Nature and Role of Theory in Metabolic Control), which built on earlier work of Higgins (1963, 1965). Although the main ideas in this theory have become much more widely accepted by biochemists as a whole in the past few years, acceptance is far from universal, and criticisms have come from various directions. Some of these are set out and disc作者: Vulnerary 時間: 2025-3-26 22:57
History and Original Thoughts on the Control Theoretic Approacho some, at least, I am considered a grandfather of the field. I am not sure how I came to be a grandfather without ever being a father. Yet let that be, for I accept the accolade with sincere appreciation even though I think it partly, if not wholly, apocryphal. But if there are grandfathers, there 作者: 發(fā)出眩目光芒 時間: 2025-3-27 02:13 作者: fender 時間: 2025-3-27 05:50 作者: 烤架 時間: 2025-3-27 10:31
Comparison of Accuracy of Alternative Models for Biochemical Pathways(1969., 1970, 1971, 1972), ., originated by Kacser & Bums (1973) and Heinrich and Rapoport (1974, 1975), and the theory originated by Crabtree & Newsholme (1978, 1985, 1987), which I shall call . (cf. Sorribas & Savageau, 1989.). All three theories have the ultimate goal to yield insight into the fu作者: dapper 時間: 2025-3-27 15:30 作者: 有抱負(fù)者 時間: 2025-3-27 18:11 作者: Nonflammable 時間: 2025-3-27 22:51
The Structural Approach to Metabolic Control Analysis II: Geometrical Aspectses a way of analysing the sensitivity of a metabolic system to perturbation of the environment or of its internal state. This method extends and generalizes the matrix method proposed by Fell & Sauro (1985) and Westerhoff & Chen (1984).作者: Adenocarcinoma 時間: 2025-3-28 05:21 作者: escalate 時間: 2025-3-28 07:14
Performance Indices in Metabolic Systems: a Criterion for Evaluating Effectiveness in Metabolic Regus (enzymic rates, and transport across membrane or combination of them). Furthermore, there must be at least one source metabolite or first metabolite and at least one final product. The pathway occurs in a viscous medium, sometimes heterogeneous with different diffusion rates in likely spatially or作者: 神圣在玷污 時間: 2025-3-28 13:04 作者: altruism 時間: 2025-3-28 16:35
Zero-order Ultrasensitivity in Interconvertible Enzyme Systemsse are to be elicited by relatively small changes in stimulus, i.e. substrate or effector in the case of enzymes (Koshland ., 1982). An important role is nevertheless retained in metabolic systems by other reactions in the pathway since these will determine whether any abrupt change is propagated be作者: conscribe 時間: 2025-3-28 19:03
Metabolic Control by the Cyclic Cascade Mechanism: a Study of , Glutamine Synthetasece the amide nitrogen atom of glutamine is a preferred nitrogen source for the biosynthesis of virtually all amino acids, purine and pyrimidine nucleotides, NAD and glucosamine-6-phosphate, it is rigorously regulated in bacteria which synthesize their own amino acids. [For reviews, see Stadtman & Gi作者: Hamper 時間: 2025-3-28 23:34
Properties Needed for the Enzymes of an Interconvertible Cascade to Generate a Highly Sensitive Respnsitivity in the response of a pathway to an effector. Consequently the understanding of the mechanisms that allow a high degree of sensitivity should constitute a major goal of any theory of metabolic control. Cooperativity in the response of an enzyme to an effector is undoubtedly an important mec作者: 搜尋 時間: 2025-3-29 05:17 作者: Lacerate 時間: 2025-3-29 09:56 作者: Ischemia 時間: 2025-3-29 13:22 作者: 鉆孔 時間: 2025-3-29 16:00 作者: Recessive 時間: 2025-3-29 19:44 作者: Expiration 時間: 2025-3-30 03:58
The Spread Relation and Its Applications,o some, at least, I am considered a grandfather of the field. I am not sure how I came to be a grandfather without ever being a father. Yet let that be, for I accept the accolade with sincere appreciation even though I think it partly, if not wholly, apocryphal. But if there are grandfathers, there 作者: 競選運(yùn)動 時間: 2025-3-30 05:22 作者: Dappled 時間: 2025-3-30 09:14
https://doi.org/10.1007/978-3-662-02915-2 from the large number of interacting components in biochemical systems and the complex nonlinear character of these interactions. The Power-Law Formalism (Savageau, 1969.) is an example of such a language that underlies several recent attempts to develop an understanding of integrated biochemical s作者: etiquette 時間: 2025-3-30 14:07 作者: 引水渠 時間: 2025-3-30 19:19
Essentials of Nevanlinna Theory,e . developed by Savageau (1969) and . formulated independently by Kacser & Bums (1973) and Heinrich & Rapoport (1974). Crabtree & Newsholme (1985, 1987) have combined aspects of these two theories in their treatment of control of metabolism. (This theory has been called . by Savageau and colleagues作者: 我的巨大 時間: 2025-3-30 23:51
Essentials of Nevanlinna Theory,s environment nor on its internal state, but only on its structure. The models used in metabolic control theory, or more generally in biochemical kinetic theory, can be constructed in two steps: defining first the stoicheiometric reaction scheme, and giving then the expressions of the rate functions作者: ENNUI 時間: 2025-3-31 04:07
