標(biāo)題: Titlebook: Computational Systems Biology in Medicine and Biotechnology; Methods and Protocol Sonia Cortassa,Miguel A. Aon Book 2022 This is a U.S. gov [打印本頁] 作者: Forestall 時(shí)間: 2025-3-21 18:02
書目名稱Computational Systems Biology in Medicine and Biotechnology影響因子(影響力)
書目名稱Computational Systems Biology in Medicine and Biotechnology影響因子(影響力)學(xué)科排名
書目名稱Computational Systems Biology in Medicine and Biotechnology網(wǎng)絡(luò)公開度
書目名稱Computational Systems Biology in Medicine and Biotechnology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Computational Systems Biology in Medicine and Biotechnology被引頻次
書目名稱Computational Systems Biology in Medicine and Biotechnology被引頻次學(xué)科排名
書目名稱Computational Systems Biology in Medicine and Biotechnology年度引用
書目名稱Computational Systems Biology in Medicine and Biotechnology年度引用學(xué)科排名
書目名稱Computational Systems Biology in Medicine and Biotechnology讀者反饋
書目名稱Computational Systems Biology in Medicine and Biotechnology讀者反饋學(xué)科排名
作者: Adrenal-Glands 時(shí)間: 2025-3-21 23:32
Single-Cell Analysis of the Transcriptome and Epigenomeons and resultant gene expression changes in single cells provides unprecedented resolution and insight into cellular diversity, modes of gene regulation, transcription factor dynamics and 3D genome organization. In this chapter, we summarize the transformative single-cell epigenomic technologies th作者: 執(zhí)拗 時(shí)間: 2025-3-22 02:01
Automating Assignment, Quantitation, and Biological Annotation of Redox Proteomics Datasets with Proger and identify more redox regulated sites in proteins, they provide a systems-wide characterization of redox regulation across cellular organelles and regulatory networks. However, these large proteomic datasets require substantial data processing and analysis in order to fully interpret and compr作者: 踉蹌 時(shí)間: 2025-3-22 05:12 作者: Synchronism 時(shí)間: 2025-3-22 12:08
MITODYN: An Open Source Software for Quantitative Modeling of Mitochondrial and Cellular Energy Meta sides of the inner mitochondrial membrane, that ATP synthase uses to generate ATP. This process constitutes a bridge between carbohydrates’ central metabolism and ATP-consuming cellular functions. Moreover, the RC is responsible for a large part of reactive oxygen species (ROS) generation that play作者: 隼鷹 時(shí)間: 2025-3-22 13:05 作者: 隼鷹 時(shí)間: 2025-3-22 17:46 作者: Infiltrate 時(shí)間: 2025-3-23 00:55
Unraveling Pathways of Health and Lifespan with Integrated Multiomics Approachesal strategy where the confounding effects of diet and feeding regimens can be dissected. In this chapter, we use integrated analysis of multiomics (transcriptomics–metabolomics) data in liver from mice to gain insight into pathways associated with improved health and survival. We identify a unique m作者: 推測 時(shí)間: 2025-3-23 03:50 作者: 沙漠 時(shí)間: 2025-3-23 09:33
Multiscale Modeling of the Mitochondrial Origin of Cardiac Reentrant and Fibrillatory Arrhythmiasscalates to influence the rhythm of the heart remains incompletely understood. This is due, in part, to the complexity of the interactions formed by cardiac electrical, mechanical, and metabolic subsystems at various spatiotemporal scales that is difficult to fully comprehend solely with experiments作者: 可用 時(shí)間: 2025-3-23 11:50 作者: 舔食 時(shí)間: 2025-3-23 16:12
Computational Approaches and Tools as Applied to the Study of Rhythms and Chaos in Biology) correlations, chaotic dynamics up to brown and white noise. Herein, we propose a comprehensive analytical strategy for identifying, representing, and analyzing biological time series, focusing on two strongly linked dynamics: periodic (oscillatory) rhythms and chaos. Understanding the underlying t作者: 取之不竭 時(shí)間: 2025-3-23 19:41 作者: Aviary 時(shí)間: 2025-3-23 22:20
1064-3745 ation advice from the experts.This volume addresses the latest state-of-the-art systems biology-oriented approaches that--driven by big data and bioinformatics--are utilized by Computational Systems Biology, an interdisciplinary field that bridges experimental tools with computational tools to tackl作者: 思考才皺眉 時(shí)間: 2025-3-24 05:21 作者: 變色龍 時(shí)間: 2025-3-24 10:08 作者: Negligible 時(shí)間: 2025-3-24 11:06 作者: 未開化 時(shí)間: 2025-3-24 16:28
John G. Francis,Leslie P. Francisics data from human plasma and skeletal muscle, where the combination with epidemiological models identified a set of mitochondrial, spliceosome, and senescence proteins as well as the role of energetic pathways such as glycolysis, and electron transport pathways that regulate the aging process.作者: Antimicrobial 時(shí)間: 2025-3-24 20:00
Single-Cell Analysis of the Transcriptome and Epigenomeat have deepened our understanding of the fundamental principles of gene regulation. We provide a historical perspective of these methods, brief procedural outline with emphasis on the computational tools used to meaningfully dissect information. Our overall goal is to aid scientists using these technologies in their favorite system of interest.作者: 自戀 時(shí)間: 2025-3-25 03:09
Understanding the Human Aging Proteome Using Epidemiological Modelsics data from human plasma and skeletal muscle, where the combination with epidemiological models identified a set of mitochondrial, spliceosome, and senescence proteins as well as the role of energetic pathways such as glycolysis, and electron transport pathways that regulate the aging process.作者: pacific 時(shí)間: 2025-3-25 03:51
https://doi.org/10.1007/978-94-007-1620-9re, we describe a multiscale multiphysics heart simulator, UT-Heart, which uses unique technologies to realize the abovementioned features. As examples of its applications, models for cardiac resynchronization therapy and surgery for congenital heart disease will be also shown.作者: accomplishment 時(shí)間: 2025-3-25 09:28
J. Drew Lanham,Maria A. Whiteheadyers to examine how regional mitochondrial dysfunction elicits abnormal electrical activity, such as rebound and spiral waves, leading to reentry and fibrillation in cardiac tissue. We anticipate that this advanced modeling technology will enable new insights into the mechanisms by which changes in subcellular organelles can impact organ function.作者: kidney 時(shí)間: 2025-3-25 15:29 作者: wangle 時(shí)間: 2025-3-25 15:51
Sustaining the World‘s Wetlandsthat can be tested at the bench. To implement and perform the computational steps in the methodology, we present user-friendly tools, computer code, and guidelines. The principles of this methodology are general and can be adapted to other model organisms to extract mechanistic knowledge of their morphogenesis.作者: AVOID 時(shí)間: 2025-3-25 22:30 作者: ANNUL 時(shí)間: 2025-3-26 00:26 作者: CALL 時(shí)間: 2025-3-26 08:04
Automated Quantification and Network Analysis of Redox Dynamics in Neuronal Mitochondrialed interorganellar networks. Therefore, advanced analysis and postprocessing tools are needed to enable automated analysis to fully quantitate mitochondrial signaling events and decipher their complex spatiotemporal connectedness. Herein, we present a protocol for recording and automating analyses of signaling in neuronal mitochondrial networks.作者: ticlopidine 時(shí)間: 2025-3-26 10:16
Computational Systems Biology of Morphogenesisthat can be tested at the bench. To implement and perform the computational steps in the methodology, we present user-friendly tools, computer code, and guidelines. The principles of this methodology are general and can be adapted to other model organisms to extract mechanistic knowledge of their morphogenesis.作者: PALMY 時(shí)間: 2025-3-26 15:04
Book 2022mputational Systems Biology, an interdisciplinary field that bridges experimental tools with computational tools to tackle complex questions at the frontiers of knowledge in medicine and biotechnology. The chapters in this book are organized into six parts: systems biology of the genome, epigenome, 作者: CARE 時(shí)間: 2025-3-26 18:02
SpringerBriefs in Environmental Scienceof detailed kinetic, and in general stoichiometric models of metabolic networks at the steady state, to facilitate their optimization and avoid numerical problems. Representative results illustrate the powerful mechanistic insights that can be gained from this integrative and quantitative methodology.作者: 施魔法 時(shí)間: 2025-3-26 21:57 作者: 哎呦 時(shí)間: 2025-3-27 01:44 作者: Credence 時(shí)間: 2025-3-27 08:11 作者: 天賦 時(shí)間: 2025-3-27 11:59 作者: hemorrhage 時(shí)間: 2025-3-27 14:19 作者: 裙帶關(guān)系 時(shí)間: 2025-3-27 19:17
978-1-0716-1833-2This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright pro作者: 過濾 時(shí)間: 2025-3-27 23:06 作者: Iniquitous 時(shí)間: 2025-3-28 05:09 作者: HAVOC 時(shí)間: 2025-3-28 10:00
John Barry,Marcel Wissenburg,Marius de Geuscellular, and pathophysiologic roles of circRNAs are not fully known, but their impact on gene expression programs is beginning to emerge, as circRNAs often associate with RNA-binding proteins and nucleic acids. With rising interest in identifying circRNAs associated with disease processes, it has b作者: 妨礙議事 時(shí)間: 2025-3-28 13:57 作者: Highbrow 時(shí)間: 2025-3-28 16:07 作者: 連接 時(shí)間: 2025-3-28 19:38 作者: 沉思的魚 時(shí)間: 2025-3-29 00:08 作者: certitude 時(shí)間: 2025-3-29 05:03 作者: GRACE 時(shí)間: 2025-3-29 10:07 作者: 樂器演奏者 時(shí)間: 2025-3-29 12:30
Florian K?nig,Alexandros Paramythisal strategy where the confounding effects of diet and feeding regimens can be dissected. In this chapter, we use integrated analysis of multiomics (transcriptomics–metabolomics) data in liver from mice to gain insight into pathways associated with improved health and survival. We identify a unique m作者: 管理員 時(shí)間: 2025-3-29 18:04
https://doi.org/10.1007/978-94-007-1620-9n levels. However, it is difficult to comprehend the complex interactions occurring among the building blocks of biological systems across these scales. Recent advances in computational science supported by innovative high-performance computer hardware make it possible to develop a multiscale multip作者: Eosinophils 時(shí)間: 2025-3-29 21:19 作者: 易彎曲 時(shí)間: 2025-3-30 00:56
Abdelnaser Omran,Fulla Ismail Sharafathology. Mitochondria are both the target and the origin of multiple signaling events, including redox processes and calcium signaling which are important for organellar function and homeostasis. One way to interrogate mitochondrial function is by live cell imaging. Elaborated approaches perform im作者: BIPED 時(shí)間: 2025-3-30 07:39
Leadership: Theory and Practice,) correlations, chaotic dynamics up to brown and white noise. Herein, we propose a comprehensive analytical strategy for identifying, representing, and analyzing biological time series, focusing on two strongly linked dynamics: periodic (oscillatory) rhythms and chaos. Understanding the underlying t作者: defendant 時(shí)間: 2025-3-30 08:52
Sustaining the World‘s Wetlandsregulation and their feedback loops. Furthermore, these regulatory interactions are also linked to the biophysical forces that shape a developing tissue, creating complex interactions responsible for emergent patterns and forms. Here we show how a computational systems biology approach can aid in th作者: hidebound 時(shí)間: 2025-3-30 12:25
Book 2022olecular Biology. series format, chapters include introductions to their respective topics; criteria utilized for applying specific methodologies; lists of the necessary materials, reagents, software, databases, algorithms, mathematical models, and dedicated analytical procedures; step-by-step, read作者: Nmda-Receptor 時(shí)間: 2025-3-30 19:08 作者: MORT 時(shí)間: 2025-3-30 23:12
Automating Assignment, Quantitation, and Biological Annotation of Redox Proteomics Datasets with Promodification on any residue..Here we demonstrate how to use ProteoSushi to analyze a large, public cysteine redox proteomics dataset. ProteoSushi assigns each modified peptide to shared proteins and genes, sums or averages signal intensities for each modified site of interest, and annotates each mod作者: DIS 時(shí)間: 2025-3-31 04:28 作者: Stress 時(shí)間: 2025-3-31 06:07 作者: 勉勵(lì) 時(shí)間: 2025-3-31 12:17
Computational Approaches and Tools as Applied to the Study of Rhythms and Chaos in Biologyof a combined approach employing different analytical methodologies to synergize their strengths and mitigate their weaknesses. Specifically, we describe advantages and caveats to consider for applying probability distribution, autocorrelation analysis, phase space reconstruction, Lyapunov exponent
