標(biāo)題: Titlebook: Computational Methods in Systems Biology; 6th International Co Monika Heiner,Adelinde M. Uhrmacher Conference proceedings 2008 Springer-Ver [打印本頁(yè)] 作者: miserly 時(shí)間: 2025-3-21 18:54
書目名稱Computational Methods in Systems Biology影響因子(影響力)
書目名稱Computational Methods in Systems Biology影響因子(影響力)學(xué)科排名
書目名稱Computational Methods in Systems Biology網(wǎng)絡(luò)公開度
書目名稱Computational Methods in Systems Biology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Computational Methods in Systems Biology被引頻次
書目名稱Computational Methods in Systems Biology被引頻次學(xué)科排名
書目名稱Computational Methods in Systems Biology年度引用
書目名稱Computational Methods in Systems Biology年度引用學(xué)科排名
書目名稱Computational Methods in Systems Biology讀者反饋
書目名稱Computational Methods in Systems Biology讀者反饋學(xué)科排名
作者: CROW 時(shí)間: 2025-3-21 20:20 作者: legislate 時(shí)間: 2025-3-22 02:34
An Exact Brownian Dynamics Method for Cell Simulation,copy and single particle tracking, evidences are accumulating that the cells may be taking advantage of intracellular spatial features to realize and optimize their functions. Computer simulation is a useful means to bridge the gap between the microscopic, physico-chemical picture of how macro-molec作者: 浪費(fèi)時(shí)間 時(shí)間: 2025-3-22 07:48 作者: Ingenuity 時(shí)間: 2025-3-22 12:23 作者: INTER 時(shí)間: 2025-3-22 15:30 作者: INTER 時(shí)間: 2025-3-22 17:03
Functional Evolution of Ribozyme-Catalyzed Metabolisms in a Graph-Based Toy-Universe,y abstract and specific, have proven to be helpful in explaining properties and behavior observed in real world metabolic reaction networks, such as the occurrence of hub-metabolites. We propose here a more complex and intuitive graph-based model combined with an artificial chemistry. Instead of dif作者: Restenosis 時(shí)間: 2025-3-23 00:02 作者: NOTCH 時(shí)間: 2025-3-23 04:01
A Language for Biochemical Systems,BS with features directed towards practical, large-scale applications, thus yielding LBS: a .. The two main extensions are expressions for modifying large complexes in a step-wise manner and parameterised modules with a notion of subtyping; LBS also has nested declarations of species and compartment作者: 榨取 時(shí)間: 2025-3-23 09:33
The Attributed Pi Calculus,ility, the calculus is parametrized with the language . which defines possible values of attributes. . can express polyadic synchronization as in pi@ and thus diverse compartment organizations. A non-deterministic and a stochastic semantics, where rates may depend on attribute values, is introduced.作者: irritation 時(shí)間: 2025-3-23 10:34 作者: BOLUS 時(shí)間: 2025-3-23 13:58
Automatic Complexity Analysis and Model Reduction of Nonlinear Biochemical Systems,t time scales. In this paper we present and apply two novel methods aimed at automatic complexity and model reduction by numerical algorithms. The first method combines dynamic sensitivity analysis with singular value decomposition. The aim is to determine the minimal dimension of the kinetic model 作者: 未開化 時(shí)間: 2025-3-23 21:11
Formal Analysis of Abnormal Excitation in Cardiac Tissue,mal analysis of cardiac arrhythmic events, namely Early Afterdepolarizations (EADs). The goal is to quantify (for the first time) the contribution of the overall sodium (Na.), potassium (K.) and calcium (Ca.) currents to the occurrence of EADs during the plateau phase of the cardiac action potential作者: bleach 時(shí)間: 2025-3-24 00:41 作者: 阻擋 時(shí)間: 2025-3-24 03:58
,SED-ML – An XML Format for the Implementation of the MIASE Guidelines,epted formats to encode the structure of models. However, the problem of describing the simulations to be run using those models has not yet been tackled in a satisfactory way. The community believes that providing detailed information about simulation recipes will highly improve the efficient use o作者: 舊式步槍 時(shí)間: 2025-3-24 07:13
On Parallel Stochastic Simulation of Diffusive Systems,lgorithms to simulate them, including the well-known and widespread Gillespie SSA, are strictly sequential. Here we investigate, in a general way, how to characterize the simulation of biochemical systems in terms of Discrete Event Simulation. We dissect their inherent parallelism in order both to e作者: 脖子 時(shí)間: 2025-3-24 13:49 作者: BAIL 時(shí)間: 2025-3-24 18:55 作者: HEPA-filter 時(shí)間: 2025-3-24 21:18 作者: 杠桿 時(shí)間: 2025-3-25 00:37
Conference proceedings 2008tock, Germany, in September 2008. The 21 revised full papers presented together with the summaries of 5 invited papers were carefully reviewed and selected from more than 60 submissions. The papers cover theoretical or applied contributions that are motivated by a biological question focusing on mod作者: INCH 時(shí)間: 2025-3-25 04:38 作者: Peristalsis 時(shí)間: 2025-3-25 11:26 作者: 表否定 時(shí)間: 2025-3-25 12:28
Component-Based Modelling of RNA Structure Folding,with other model components like RNA binding proteins. An example of transcriptional attenuation will be given where model components of RNA polymerase, the folding RNA molecule, and the translating ribosome play together in a composed dynamic model.作者: FAWN 時(shí)間: 2025-3-25 19:39 作者: Relinquish 時(shí)間: 2025-3-25 23:38 作者: 新鮮 時(shí)間: 2025-3-26 03:28 作者: 使苦惱 時(shí)間: 2025-3-26 05:12 作者: 威脅你 時(shí)間: 2025-3-26 08:45
Successful Science and Engineering Teachingoptimize their functions. Computer simulation is a useful means to bridge the gap between the microscopic, physico-chemical picture of how macro-molecules diffuse and react, and the scales of time and space where biochemistry and physiology take place.作者: 是剝皮 時(shí)間: 2025-3-26 16:28
An Exact Brownian Dynamics Method for Cell Simulation,optimize their functions. Computer simulation is a useful means to bridge the gap between the microscopic, physico-chemical picture of how macro-molecules diffuse and react, and the scales of time and space where biochemistry and physiology take place.作者: 主動(dòng) 時(shí)間: 2025-3-26 19:00 作者: 原諒 時(shí)間: 2025-3-26 23:54 作者: Basal-Ganglia 時(shí)間: 2025-3-27 03:25
https://doi.org/10.1007/978-1-4020-6910-9tax, static semantics and a translation to a variant of coloured Petri nets. Translation to other formalisms such as ordinary differential equations and continuous time Markov chains is also possible.作者: 失望未來 時(shí)間: 2025-3-27 07:48 作者: 死亡 時(shí)間: 2025-3-27 12:38 作者: 狗舍 時(shí)間: 2025-3-27 16:52
https://doi.org/10.1007/978-981-99-9291-1algorithms. This paper presents the results of an empirical study, which subsumes several thousand simulation runs. It aims at exploring the performance of different SSA implementations and comparing them to an approximation via .-Leaping, while using different event queues and random number generators.作者: DRAFT 時(shí)間: 2025-3-27 17:52
Social Movement Targeting Companiesso provides guarantees on the probability of it generating Type-I (i.e., false-positive) and Type-II (i.e., false-negative) errors. Moreover, these error bounds are pre-specified by the user. We demonstrate . by verifying stochastic effects and bistability in the dynamics of the T-cell receptor signaling network.作者: byline 時(shí)間: 2025-3-27 22:42 作者: Incorruptible 時(shí)間: 2025-3-28 03:02
A Language for Biochemical Systems,tax, static semantics and a translation to a variant of coloured Petri nets. Translation to other formalisms such as ordinary differential equations and continuous time Markov chains is also possible.作者: 浪蕩子 時(shí)間: 2025-3-28 06:31
Formal Analysis of Abnormal Excitation in Cardiac Tissue,by simulations with classical AP models based on complex systems of nonlinear differential equations. Our approach offers a simple formal technique for the prediction of conditions leading to arrhythmias (EADs) from a limited set of experimental measurements, and can be invaluable for devising new anti-arrhythmic strategies.作者: 消耗 時(shí)間: 2025-3-28 10:36
On Parallel Stochastic Simulation of Diffusive Systems,to select the parallelization technique which provides the greater benefits, as well as to touch its limits. We then focus on reaction-diffusion systems: we design and implement an efficient parallel algorithm for simulating such systems that include both reactions between entities and movements throughout the space.作者: 顛簸地移動(dòng) 時(shí)間: 2025-3-28 16:53 作者: wreathe 時(shí)間: 2025-3-28 20:07
Statistical Model Checking in ,: Applications to the Automated Analysis of T-Cell Receptor Signalinso provides guarantees on the probability of it generating Type-I (i.e., false-positive) and Type-II (i.e., false-negative) errors. Moreover, these error bounds are pre-specified by the user. We demonstrate . by verifying stochastic effects and bistability in the dynamics of the T-cell receptor signaling network.作者: 進(jìn)取心 時(shí)間: 2025-3-29 01:55
On a Continuous Degree of Satisfaction of Temporal Logic Formulae with Applications to Systems Biolormalized in temporal logic. We also show how it can be used to define a measure of robustness of a biological model with respect to some specification. These methods are evaluated on models of the cell cycle and of the MAPK signalling cascade.作者: Constant 時(shí)間: 2025-3-29 03:35 作者: 寬宏大量 時(shí)間: 2025-3-29 08:02
Courses for Non-science Studentsic parameters are usually absent for most systems of biological interest. Moreover, the models consist of a large number of variables, are strongly nonlinear and include different time-scales, which make them difficult to handle both mathematically and computationally.作者: 迎合 時(shí)間: 2025-3-29 13:16
Successful Science and Engineering Teachingupported analysis techniques include stochastic simulation at the molecular level, ordinary di..erential equations, probabilistic model checking and numerical analysis of a continuous time Markov chain.作者: observatory 時(shí)間: 2025-3-29 16:16 作者: ALIAS 時(shí)間: 2025-3-29 22:35
https://doi.org/10.1007/978-1-4020-6910-9 The stochastic semantics is based on continuous time Markov chains. A simulation algorithm is developed which is firmly rooted in this stochastic semantics. Two examples underline the applicability of . to systems biology: Euglena’s movement in phototaxis, and cooperative protein binding in gene regulation of bacteriophage lambda.作者: 抓住他投降 時(shí)間: 2025-3-30 03:29
https://doi.org/10.1007/978-1-4020-6910-9me. We illustrate these features with a model of an existing biological system, a simple oscillatory pathway in cyanobacteria. We then discuss future research directions, in particular routes to applying the calculus in the study of evolutionary properties of biochemical pathways.作者: 解開 時(shí)間: 2025-3-30 06:17 作者: 熄滅 時(shí)間: 2025-3-30 11:21 作者: 大火 時(shí)間: 2025-3-30 12:30 作者: 籠子 時(shí)間: 2025-3-30 16:56 作者: 整體 時(shí)間: 2025-3-30 22:12
Successful Science and Engineering Teachingival or fecundity. We define potential fitness correlates, describe methods for automatically measuring them from simulations and implement a simple clock using the Gillespie stochastic simulation algorithm within StochKit. We determine what fraction of examined mutations with small effects on the r作者: 糾纏,纏繞 時(shí)間: 2025-3-31 04:06 作者: 諄諄教誨 時(shí)間: 2025-3-31 06:30 作者: macabre 時(shí)間: 2025-3-31 11:17 作者: SEVER 時(shí)間: 2025-3-31 14:57
A Partial Granger Causality Approach to Explore Causal Networks Derived From Multi-parameter Data,the participating entities. We also demonstrate the ability of our method to deal with latent and exogenous variables present in the system. We then applied this method to a highly replicated gene expression microarray time series data to infer causal influences between gene expression events involv作者: 摘要記錄 時(shí)間: 2025-3-31 19:02 作者: 燒瓶 時(shí)間: 2025-3-31 22:42
The Distribution of Mutational Effects on Fitness in a Simple Circadian Clock,ival or fecundity. We define potential fitness correlates, describe methods for automatically measuring them from simulations and implement a simple clock using the Gillespie stochastic simulation algorithm within StochKit. We determine what fraction of examined mutations with small effects on the r作者: Inflammation 時(shí)間: 2025-4-1 03:30
,SED-ML – An XML Format for the Implementation of the MIASE Guidelines, exchange of part of the information required to implement the MIASE guidelines. SED-ML is independent of the formats used to encode the models – as long as they are expressed in XML –, and it is independent of the software tools used to run the simulations. Several test implementations are being de作者: correspondent 時(shí)間: 2025-4-1 08:30
Courses for Non-science Studentslving genes, RNAs, proteins, metabolites, and small signalling molecules. In theory, it is possible to write down mathematical models of these networks, and study these by means of classical analysis and simulation tools. In practice, this is not easy to achieve though, as quantitative data on kinet作者: Brain-Waves 時(shí)間: 2025-4-1 11:12
Successful Science and Engineering Teachingic style of modelling is adopted, and a variety of analysis techniques can be applied to a single model expression. Such an approach facilitates easy validation of analysis results when the analyses address the same issues [3] and enhanced insight when the analyses are complementary [4]. Currently s作者: landfill 時(shí)間: 2025-4-1 16:29 作者: Bravado 時(shí)間: 2025-4-1 21:11
Writing to Learn: Reflective Writingormation: Chemical concentration such as calcium ions, chemical modification such as phosphorylation cascades, conformational information such as allosteric modulations, and electrical signals such as membrane depolarisation. One cannot claim to understand neuronal function when focussing on a singl作者: 女上癮 時(shí)間: 2025-4-2 00:59 作者: CURT 時(shí)間: 2025-4-2 06:36
