標(biāo)題: Titlebook: Computational Methods in Systems Biology; International Confer Muffy Calder,Stephen Gilmore Conference proceedings 2007 Springer-Verlag Ber [打印本頁(yè)] 作者: Negate 時(shí)間: 2025-3-21 19:53
書目名稱Computational Methods in Systems Biology影響因子(影響力)
書目名稱Computational Methods in Systems Biology影響因子(影響力)學(xué)科排名
書目名稱Computational Methods in Systems Biology網(wǎng)絡(luò)公開度
書目名稱Computational Methods in Systems Biology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Computational Methods in Systems Biology被引頻次
書目名稱Computational Methods in Systems Biology被引頻次學(xué)科排名
書目名稱Computational Methods in Systems Biology年度引用
書目名稱Computational Methods in Systems Biology年度引用學(xué)科排名
書目名稱Computational Methods in Systems Biology讀者反饋
書目名稱Computational Methods in Systems Biology讀者反饋學(xué)科排名
作者: Diverticulitis 時(shí)間: 2025-3-21 22:18
Simultaneous Stochastic Simulation of Multiple Perturbations in Biological Network Models, inaccurate or perturbed. An important topic is thus the sensitivity of analysis results to parameter perturbations. This investigates how seriously potential parameter perturbations affect the analysis results and to which parameters the results are most sensitive. In this paper, a stochastic simul作者: NICHE 時(shí)間: 2025-3-22 02:15 作者: Asperity 時(shí)間: 2025-3-22 05:10
On the Analysis of Numerical Data Time Series in Temporal Logic, automatically verify their satisfaction in both qualitative and quantitative models. In this paper, we propose a finite time horizon model-checking algorithm for the existential fragment of LTL with numerical constraints over the reals, with the ability to compute the range of values of the real va作者: 諂媚于人 時(shí)間: 2025-3-22 09:33
Context Sensitivity in Logical Modeling with Time Delays,automata can be very helpful. The formalism focussed on in this paper starts from the logical description developed by R. Thomas to capture network structure and qualitative behavior of a system. Using the framework of timed automata, the analysis of the dynamics can be refined by adding a continuou作者: CLASP 時(shí)間: 2025-3-22 15:33
Stochastic Simulation of Biological Systems with Dynamical Compartment Structure,led by means of concurrent calculi. While the faithful modelling of bio-systems often requires multi-compartment semantics, the original Gillespie algorithm considers only one fixed-size volume. In this paper we introduce an extended formalisation of the above algorithm which preserves the original 作者: CLASP 時(shí)間: 2025-3-22 18:22 作者: MORT 時(shí)間: 2025-3-22 23:54 作者: 失望未來(lái) 時(shí)間: 2025-3-23 02:26
Reconstruction of Mammalian Cell Cycle Regulatory Network from Microarray Data Using Stochastic Logding the computation of the Markov model parameters is able to reconstruct the topology of the SLN model in polynomial time instead of exponential as in previous study [29]. To test the performance of the method, we apply it to different datasets (both synthetic and experimental) covering the expres作者: fatuity 時(shí)間: 2025-3-23 07:51
An Automated Translation from a Narrative Language for Biological Modelling into Process Algebra,ily usable by life scientists in modelling intra-cellular systems. Secondly, we provide an automatic translation of the proposed language into Beta-binders, a bio-inspired process calculus, which allows life scientists to formally analyse and simulate their models. We use the Gp130 signalling pathwa作者: 嗎啡 時(shí)間: 2025-3-23 11:52
Expressive Models for Synaptic Plasticity,exploits process calculi as formal grounds, enjoys nice compositional properties, has a direct computational implementation that supports simulation trials, and, to our knowledge, represents the first process calculi based model of a presynaptic terminal. Simulation results have shown coherence with作者: 南極 時(shí)間: 2025-3-23 17:53 作者: licence 時(shí)間: 2025-3-23 22:00 作者: Digitalis 時(shí)間: 2025-3-23 23:05
Reconstructing Metabolic Pathways by Bidirectional Chemical Search, in a specific organism. Current knowledge of biochemical pathways as stored in public databases such as KEGG, is based on carefully curated genomic evidence for the presence of specific metabolites and enzymes that activate particular biochemical reactions. In this paper, we present an efficient me作者: 壟斷 時(shí)間: 2025-3-24 05:01 作者: 范圍廣 時(shí)間: 2025-3-24 10:22 作者: Aids209 時(shí)間: 2025-3-24 12:45
Efficient, Correct Simulation of Biological Processes in the Stochastic Pi-calculus,ficiency. The algorithm is proved correct with respect to the calculus, and then used as a basis for implementing the latest version of the SPiM stochastic simulator. The algorithm is also suitable for generating graphical animations of simulations, in order to visualise system dynamics.作者: 遷移 時(shí)間: 2025-3-24 16:38
https://doi.org/10.1007/978-1-4302-1605-6character and strength of interactions as well as time delays are context sensitive in the sense that they depend on the current state of the system. We propose an enhancement of the approach described above, integrating both structural and temporal context sensitivity.作者: 娘娘腔 時(shí)間: 2025-3-24 21:32 作者: 蔓藤圖飾 時(shí)間: 2025-3-25 00:47 作者: FOLLY 時(shí)間: 2025-3-25 07:08
Decision Diagrams for the Representation and Analysis of Logical Models of Genetic Networks,operties of the regulatory graphs. In particular, we address the question of determining conditions insuring the functionality of feedback circuits, as well as the identification of stable states. Finally, we apply these algorithms to logical models of T cell activation and differentiation.作者: Ptsd429 時(shí)間: 2025-3-25 10:48
Initiating and Executing a CRM Phaseriables occurring in a formula that makes it true in a model. We illustrate this approach for the analysis of biological data time series, provide a set of biologically relevant patterns of formulas, and evaluate them on models of the cell cycle control and MAPK signal transduction.作者: 審問(wèn),審訊 時(shí)間: 2025-3-25 13:35 作者: frozen-shoulder 時(shí)間: 2025-3-25 19:26 作者: fluoroscopy 時(shí)間: 2025-3-25 23:24 作者: hypotension 時(shí)間: 2025-3-26 02:30 作者: aviator 時(shí)間: 2025-3-26 07:41 作者: 節(jié)約 時(shí)間: 2025-3-26 12:16
Finding Paths to Successful Transitions,a precise definition of biochemically interpreted stochastic Petri nets. Although our framework is based on Petri nets, it can be applied more widely to other formalisms which are used to model and analyse biochemical networks.作者: 膽小懦夫 時(shí)間: 2025-3-26 13:27 作者: obeisance 時(shí)間: 2025-3-26 18:19
Stochastic Simulation of Biological Systems with Dynamical Compartment Structure,polyadic synchronisation. Despite of its conservativeness, S.@ is showed to allow flexible modelling of multiple compartments with dynamical structure and to provide increased biological faithfulness.作者: frenzy 時(shí)間: 2025-3-27 00:44
Reconstruction of Mammalian Cell Cycle Regulatory Network from Microarray Data Using Stochastic Logependencies from realistic data, our method gives consistently better results than Dynamic Bayesian Networks in terms of the number of correctly reconstructed edges, sensitivity and statistical significance.作者: 蕁麻 時(shí)間: 2025-3-27 02:50
Expressive Models for Synaptic Plasticity,learning. The two aims of our work, i.e. addressing neural mechanisms and validating and possibly improving, process calculi based modeling techniques are discussed throughout the paper, together with the results of experiments.作者: 行為 時(shí)間: 2025-3-27 08:59
A Unifying Framework for Modelling and Analysing Biochemical Pathways Using Petri Nets,a precise definition of biochemically interpreted stochastic Petri nets. Although our framework is based on Petri nets, it can be applied more widely to other formalisms which are used to model and analyse biochemical networks.作者: 使困惑 時(shí)間: 2025-3-27 09:59 作者: 鼓掌 時(shí)間: 2025-3-27 15:18 作者: tenosynovitis 時(shí)間: 2025-3-27 18:39 作者: 飲料 時(shí)間: 2025-3-27 23:58
Justin Mathena,Aaron Yetter,Hoss Hostetlerare first and second moments in the two stochastic settings. To analyse the Chemical Master Equation we use some recent work of Gadgil, Lee and Othmer, and to analyse the Chemical Langevin Equation we use Ito’s Lemma. We find that there is a perfect match—both modelling regimes give the same means, 作者: 憤慨一下 時(shí)間: 2025-3-28 03:33 作者: 挑剔為人 時(shí)間: 2025-3-28 08:23 作者: SLUMP 時(shí)間: 2025-3-28 13:10
Opportunities to Expand the Value of CRMboth the modelling and simulation framework of our study. We discuss the validation of the model against the available experimental data and we show some preliminary results obtained from the study of our model. All the analyses are based on stochastic simulation.作者: Bureaucracy 時(shí)間: 2025-3-28 17:26 作者: Frisky 時(shí)間: 2025-3-28 21:27
https://doi.org/10.1007/978-1-4302-1605-6automata can be very helpful. The formalism focussed on in this paper starts from the logical description developed by R. Thomas to capture network structure and qualitative behavior of a system. Using the framework of timed automata, the analysis of the dynamics can be refined by adding a continuou作者: 報(bào)復(fù) 時(shí)間: 2025-3-29 00:10
https://doi.org/10.1057/9781137369413led by means of concurrent calculi. While the faithful modelling of bio-systems often requires multi-compartment semantics, the original Gillespie algorithm considers only one fixed-size volume. In this paper we introduce an extended formalisation of the above algorithm which preserves the original 作者: Indelible 時(shí)間: 2025-3-29 03:35
Andrei Panibratov,Marina Latukhar multiple generations. We have used a Monte Carlo algorithm to model the process of dot partitioning and dilution by cell mitosis. A Genetic Algorithm was used to compare simulated and experiment quantum dot distributions, which shows that the dot fluorescence is divided with a stochastic variation作者: Mundane 時(shí)間: 2025-3-29 07:19 作者: Spartan 時(shí)間: 2025-3-29 14:49
Successes of the International Monetary Fundding the computation of the Markov model parameters is able to reconstruct the topology of the SLN model in polynomial time instead of exponential as in previous study [29]. To test the performance of the method, we apply it to different datasets (both synthetic and experimental) covering the expres作者: Expediency 時(shí)間: 2025-3-29 17:46 作者: 時(shí)代 時(shí)間: 2025-3-29 21:30
The IMF Staff’s View of the World: The exploits process calculi as formal grounds, enjoys nice compositional properties, has a direct computational implementation that supports simulation trials, and, to our knowledge, represents the first process calculi based model of a presynaptic terminal. Simulation results have shown coherence with作者: 顯而易見 時(shí)間: 2025-3-30 01:24 作者: condemn 時(shí)間: 2025-3-30 04:44
Finding Paths to Successful Transitions,ontinuous paradigms. Each perspective adds its contribution to the understanding of the system, thus the three approaches do not compete, but complement each other. We illustrate our approach by applying it to an extended model of the three stage cascade, which forms the core of the ERK signal trans作者: Entropion 時(shí)間: 2025-3-30 11:52
Successful African-American Men in a specific organism. Current knowledge of biochemical pathways as stored in public databases such as KEGG, is based on carefully curated genomic evidence for the presence of specific metabolites and enzymes that activate particular biochemical reactions. In this paper, we present an efficient me作者: 驕傲 時(shí)間: 2025-3-30 13:23
https://doi.org/10.1007/b108289ght in their dynamical behaviours. One qualitative approach consists in modelling regulatory networks in terms of logical equations (using either Boolean or multi-valued discretisation)..In this paper, we propose a novel implementation of the generalised logical formalism by means of Multi-valued De作者: 他去就結(jié)束 時(shí)間: 2025-3-30 16:57
Lecture Notes in Computer Sciencehttp://image.papertrans.cn/c/image/232786.jpg作者: 天空 時(shí)間: 2025-3-30 21:31
Modelling Yeast Pre-rRNA Processing,both the modelling and simulation framework of our study. We discuss the validation of the model against the available experimental data and we show some preliminary results obtained from the study of our model. All the analyses are based on stochastic simulation.作者: boisterous 時(shí)間: 2025-3-31 03:54 作者: Anticonvulsants 時(shí)間: 2025-3-31 06:14
A Formal and Integrated Framework to Simulate Evolution of Biological Pathways,ate pathway in connection with evolutionary algorithms to implement mutations. A fitness function is used to select individuals at any generation. The feasibility of the approach is demonstrated with a simple example.作者: 狂熱語(yǔ)言 時(shí)間: 2025-3-31 12:07 作者: Stress 時(shí)間: 2025-3-31 14:37 作者: 流動(dòng)才波動(dòng) 時(shí)間: 2025-3-31 20:42 作者: 懶惰人民 時(shí)間: 2025-3-31 22:14 作者: 暫停,間歇 時(shí)間: 2025-4-1 04:26 作者: 鞭子 時(shí)間: 2025-4-1 08:58
Computational Methods in Systems Biology978-3-540-75140-3Series ISSN 0302-9743 Series E-ISSN 1611-3349 作者: savage 時(shí)間: 2025-4-1 11:22