標(biāo)題: Titlebook: Computational Methods in Systems Biology; 12th International C Pedro Mendes,Joseph O. Dada,Kieran Smallbone Conference proceedings 2014 Spr [打印本頁(yè)] 作者: quick-relievers 時(shí)間: 2025-3-21 16:13
書目名稱Computational Methods in Systems Biology影響因子(影響力)
書目名稱Computational Methods in Systems Biology影響因子(影響力)學(xué)科排名
書目名稱Computational Methods in Systems Biology網(wǎng)絡(luò)公開度
書目名稱Computational Methods in Systems Biology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Computational Methods in Systems Biology被引頻次
書目名稱Computational Methods in Systems Biology被引頻次學(xué)科排名
書目名稱Computational Methods in Systems Biology年度引用
書目名稱Computational Methods in Systems Biology年度引用學(xué)科排名
書目名稱Computational Methods in Systems Biology讀者反饋
書目名稱Computational Methods in Systems Biology讀者反饋學(xué)科排名
作者: Costume 時(shí)間: 2025-3-21 21:08 作者: 物質(zhì) 時(shí)間: 2025-3-22 02:51
Model Integration and Crosstalk Analysis of Logical Regulatory Networksduce an approach for coupling models taking uncertainties concerning the crosstalk into account. Using constraintbased modeling and formal verification techniques, a pool of possible integrated models is generated in agreement with previously validated behavior of the isolated models as well as addi作者: 上下倒置 時(shí)間: 2025-3-22 05:06 作者: saturated-fat 時(shí)間: 2025-3-22 10:33 作者: 南極 時(shí)間: 2025-3-22 13:21
Radial Basis Function Approximations of Bayesian Parameter Posterior Densities for Uncertainty Analyle formation of gradients for cell guidance. One of the key issues for this class of models is the estimation of kinetic parameters from given measurement data, the so called parameter estimation. Measurement noise and the limited amount of data, give rise to uncertainty in estimates which can be ca作者: 南極 時(shí)間: 2025-3-22 19:49 作者: Engaging 時(shí)間: 2025-3-23 00:15 作者: Flatter 時(shí)間: 2025-3-23 01:41 作者: Herd-Immunity 時(shí)間: 2025-3-23 05:36
Characterization of Reachable Attractors Using Petri Net Unfoldingsg the response and differentiation capabilities of a dynamical system. In the scope of qualitative models of interaction networks, the computation of attractors reachable from a given state of the network faces combinatorial issues due to the state space explosion..In this paper, we present a new al作者: inconceivable 時(shí)間: 2025-3-23 13:46
Dynamic Modeling and Simulation of Leukocyte Integrin Activation through an Electronic Design Automaico simulations of a biochemical model allows one to test different experimental conditions, helping in the discovery of the dynamics that regulate the system. Several characteristics and issues of biological system modeling are common to the electronics system modeling, such as concurrency, reactiv作者: 諷刺 時(shí)間: 2025-3-23 16:13 作者: Feckless 時(shí)間: 2025-3-23 21:55
A Rule-Based Model of Base Excision Repairtions or whether substrate specificity is sufficient to explain how DNA intermediates are channeled from one repair enzyme to the other. In order to address these questions we designed a model of the Base Excision Repair pathway in Kappa, a rule based formalism for modeling protein-protein and prote作者: 較早 時(shí)間: 2025-3-24 00:02 作者: Exhilarate 時(shí)間: 2025-3-24 05:25
Exploring the Cellular Objective in Flux Balance Constraint-Based Models analysis (FBA). FBA requires not only the stoichiometry of the network, but also an appropriate cellular objective function and possible additional physico-chemical constraints to predict the set of resulting flux distributions of an organism..To compute the metabolic flux distributions in microbes作者: 物質(zhì) 時(shí)間: 2025-3-24 09:19
Optimization Based Design of Synthetic Oscillators from Standard Biological Partsfied performance requirements, to automatically find the circuit configuration and its tuning so that self-sustained oscillations meeting the requirements are produced. To solve this design problem, we present a methodology based on mixed-integer nonlinear optimization. This method also takes into a作者: 幾何學(xué)家 時(shí)間: 2025-3-24 14:21 作者: neuron 時(shí)間: 2025-3-24 18:13
Conference proceedings 2014er submissions. The papers are organized in topical sections on formalisms for modeling biological processes, model inference from experimental data, frameworks for model verification, validation, and analysis of biological systems, models and their biological applications, computational approaches for synthetic biology, and flash posters.作者: Type-1-Diabetes 時(shí)間: 2025-3-24 22:26 作者: 打火石 時(shí)間: 2025-3-25 00:46 作者: Nucleate 時(shí)間: 2025-3-25 07:04 作者: gout109 時(shí)間: 2025-3-25 08:37 作者: transplantation 時(shí)間: 2025-3-25 14:40 作者: characteristic 時(shí)間: 2025-3-25 16:43
Research Model and Propositions,ed models of osmostress-inducible gene expression in yeast, we show . that our stochastic control approach outperforms deterministic control design in the regulation of single cells. The present new contribution leads to envision the application of the proposed framework to . experiments on yeast.作者: 辮子帶來(lái)幫助 時(shí)間: 2025-3-25 21:29 作者: SNEER 時(shí)間: 2025-3-26 01:09 作者: deriver 時(shí)間: 2025-3-26 05:34
Towards Real-Time Control of Gene Expression at the Single Cell Level: A Stochastic Control Approached models of osmostress-inducible gene expression in yeast, we show . that our stochastic control approach outperforms deterministic control design in the regulation of single cells. The present new contribution leads to envision the application of the proposed framework to . experiments on yeast.作者: Anticoagulant 時(shí)間: 2025-3-26 11:50
Model Integration and Crosstalk Analysis of Logical Regulatory Networkstional experimental observations. Correlation- and causality-based analysis allows us to uncover the importance of particular crosstalk connections for specific functionalities leading to new biological insights and starting points for experimental design. We illustrate our approach studying crosstalk between the MAPK and mTor signaling pathways.作者: CURL 時(shí)間: 2025-3-26 13:59 作者: concert 時(shí)間: 2025-3-26 19:16 作者: 確定 時(shí)間: 2025-3-27 00:33 作者: instill 時(shí)間: 2025-3-27 02:46
Comparative Effectiveness Researchidelines for properly tuning them. The performance of this procedure and its advantages are illustrated with a well known benchmark problem considering several scenarios of data availability and measurement noise.作者: irritation 時(shí)間: 2025-3-27 08:14 作者: 憤怒事實(shí) 時(shí)間: 2025-3-27 10:49 作者: Carcinoma 時(shí)間: 2025-3-27 17:23
Uncertainty Analysis for Non-identifiable Dynamical Systems: Profile Likelihoods, Bootstrapping and n-identifiable parameters. We showed that bootstrapping, multi-start optimisation, and Fisher information matrix based approaches yield misleading results for parameters which are structurally non-identifiable. We provide a simple and intuitive explanation for this, using geometric arguments.作者: 倒轉(zhuǎn) 時(shí)間: 2025-3-27 17:47 作者: 漂亮 時(shí)間: 2025-3-27 22:40 作者: GREG 時(shí)間: 2025-3-28 05:49
Optimal Management of Agricultural Systemsve proportion of cell death caused by bystander signalling, the risk of non-lethal damage and the probability of observing bystander signalling for a given dose. This work provides the foundation for modelling bystander effects caused by biologically realistic dose distributions, with implications for cancer therapies.作者: 鳥籠 時(shí)間: 2025-3-28 06:39 作者: 搖曳 時(shí)間: 2025-3-28 10:54
A Rule-Based Model of Base Excision Repairddress these questions we designed a model of the Base Excision Repair pathway in Kappa, a rule based formalism for modeling protein-protein and protein-DNA interactions. We use this model to shed light on the key role of the scaffolding protein XRCC1 in coordinating the repair process.作者: 哎呦 時(shí)間: 2025-3-28 16:41 作者: 舉止粗野的人 時(shí)間: 2025-3-28 21:39 作者: FLACK 時(shí)間: 2025-3-29 01:11
Conference proceedings 2014 UK, in November 2014. .The 16 regular papers presented together with 6 poster papers were carefully reviewed and selected from 31 regular and 18 poster submissions. The papers are organized in topical sections on formalisms for modeling biological processes, model inference from experimental data, 作者: 無(wú)底 時(shí)間: 2025-3-29 06:30 作者: installment 時(shí)間: 2025-3-29 10:59 作者: CLOWN 時(shí)間: 2025-3-29 14:33
Trace Simplifications Preserving Temporal Logic Formulae with Case Study in a Coupled Model of the C of trace simplifications which are correct to perform for some common temporal logic formulae. We give some general soundness theorems, and apply this approach to period and phase constraints on the circadian clock and the cell cycle. In this application, temporal logic patterns are used to compute作者: Adrenaline 時(shí)間: 2025-3-29 17:24 作者: 平 時(shí)間: 2025-3-29 22:36
Exploring the Cellular Objective in Flux Balance Constraint-Based Modelserent classes of optimality criteria and the effect of single (or combinations of) standard constraints in order to improve the predictive power of intracellular flux distribution. These were evaluated to compare predicted fluxes to published experimental .C-labelling fluxomic datasets using two met作者: 集合 時(shí)間: 2025-3-30 00:18 作者: 入會(huì) 時(shí)間: 2025-3-30 05:47
Assessing Patient-Centered Outcomesand it is possible to directly query the network instead with an appropriate tool. For ensuring a good query time, we will rely on a state of the art SAT solver, working on a propositional encoding of ., and enriched with a simple SMT-like solver ensuring . consistency with stoichiometric constraint作者: 保守 時(shí)間: 2025-3-30 10:21 作者: Accede 時(shí)間: 2025-3-30 14:40
Success in Changing Environments of trace simplifications which are correct to perform for some common temporal logic formulae. We give some general soundness theorems, and apply this approach to period and phase constraints on the circadian clock and the cell cycle. In this application, temporal logic patterns are used to compute作者: Herd-Immunity 時(shí)間: 2025-3-30 20:31 作者: oncologist 時(shí)間: 2025-3-30 20:49 作者: 揮舞 時(shí)間: 2025-3-31 02:20
Health Policy Research in Surgerynservation laws. In this article, we chose to focus on sparsest sets of conservation laws. We present a greedy algorithm computing a sparsest set of conservation laws equivalent to a given set of conservation laws. Benchmarks over a subset of the curated models taken from the BioModels database are 作者: Confess 時(shí)間: 2025-3-31 09:00
Assessing Patient-Centered Outcomest sub-networks enabling the metabolic system to operate in steady state with all irreversible reactions proceeding in the appropriate direction. However, when networks are complex, the number of . quickly leads to a combinatorial explosion, preventing from drawing even simple conclusions from their 作者: condone 時(shí)間: 2025-3-31 11:58 作者: faculty 時(shí)間: 2025-3-31 16:46 作者: climax 時(shí)間: 2025-3-31 20:21
