標(biāo)題: Titlebook: Computational Methods in Systems Biology; 18th International C Alessandro Abate,Tatjana Petrov,Verena Wolf Conference proceedings 2020 Spri [打印本頁] 作者: frustrate 時(shí)間: 2025-3-21 18:02
書目名稱Computational Methods in Systems Biology影響因子(影響力)
書目名稱Computational Methods in Systems Biology影響因子(影響力)學(xué)科排名
書目名稱Computational Methods in Systems Biology網(wǎng)絡(luò)公開度
書目名稱Computational Methods in Systems Biology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Computational Methods in Systems Biology被引頻次
書目名稱Computational Methods in Systems Biology被引頻次學(xué)科排名
書目名稱Computational Methods in Systems Biology年度引用
書目名稱Computational Methods in Systems Biology年度引用學(xué)科排名
書目名稱Computational Methods in Systems Biology讀者反饋
書目名稱Computational Methods in Systems Biology讀者反饋學(xué)科排名
作者: 哎呦 時(shí)間: 2025-3-21 23:37
C. Max Schmidt M.D., Ph.D., MBAly resides in states of up- and downregulation and generates bimodal protein distributions. In the context of our invariance result, we investigate how the choice of lifetime distribution affects the rates of metastable transitions between the two modes of the distribution. The phase-type model, bei作者: FISC 時(shí)間: 2025-3-22 01:37 作者: 小卷發(fā) 時(shí)間: 2025-3-22 05:20
https://doi.org/10.1007/978-0-85729-313-8he result is completely independent of the reaction rates and depends solely on the input concentrations. The functions computed by rate-independent CRNs have been characterized mathematically as the set of piecewise linear functions from input species. However, this does not provide a mean to decid作者: 藐視 時(shí)間: 2025-3-22 11:06
Writing a Grant/Obtaining Funding bimolecular reactions. In this paper, we study the theoretical and practical complexities of the quadratic transformation. We show that both problems of minimizing either the number of variables (i.e., molecular species) or the number of monomials (i.e.?elementary reactions) in a quadratic transfor作者: NORM 時(shí)間: 2025-3-22 15:16 作者: NORM 時(shí)間: 2025-3-22 17:36 作者: Pedagogy 時(shí)間: 2025-3-22 22:01 作者: grandiose 時(shí)間: 2025-3-23 02:07 作者: 乞丐 時(shí)間: 2025-3-23 08:54 作者: 恫嚇 時(shí)間: 2025-3-23 10:51
Accelerating Reactions at the DNA Can Slow Down Transient Gene Expression a number of arbitrarily connected DNA configurations, without feedback. In our first result, we analytically show that, if all switching rates are uniformly speeded up, then, as expected, the protein transient is faster and the noise is smaller. Our second result finds that, counter-intuitively, if作者: Infirm 時(shí)間: 2025-3-23 15:57
Graphical Conditions for Rate Independence in Chemical Reaction Networkshe result is completely independent of the reaction rates and depends solely on the input concentrations. The functions computed by rate-independent CRNs have been characterized mathematically as the set of piecewise linear functions from input species. However, this does not provide a mean to decid作者: epicondylitis 時(shí)間: 2025-3-23 19:16 作者: 不能平靜 時(shí)間: 2025-3-23 23:17
Comparing Probabilistic and Logic Programming Approaches to Predict the Effects of Enzymes in a Neur a role in neurodegenerative diseases, in particular on Alzheimer Disease (AD). The first study used Microarray gene expression datasets from the Hippocampus of 10 AD patients and 13 healthy ones, the perturbation and thus the prediction was done .. The second one, used RNA-seq data from human umbil作者: Nebulous 時(shí)間: 2025-3-24 03:26
Synthesis and Simulation of Ensembles of Boolean Networks for Cell Fate Decisionr network regulating the cell fate decisions in cancer progression. It appears that the ensemble-based approach to Boolean modelling brings new insights on the variability of synergistic interacting mutations effect concerning propensity of a cancer cell to metastasize.作者: inhibit 時(shí)間: 2025-3-24 07:50
Classifier Construction in Boolean Networks Using Algebraic Methodsuse the structure of the BN and the constraints. This calls for an algebraic approach. Indeed we demonstrate that this problem can be reformulated into the language of algebraic geometry. While already interesting in itself, this allows us to use Gr?bner bases to construct an algorithm for finding s作者: 不透明 時(shí)間: 2025-3-24 11:16 作者: harmony 時(shí)間: 2025-3-24 15:34
Interval Constraint Satisfaction and Optimization for Biological Homeostasis and Multistationaritychniques to find species in biochemical systems that verify homeostasis, and a similar method for testing multistationarity. We test homeostasis, ACR and multistationarity on a large collection of biochemical models from the Biomodels and DOCSS databases. The codes used in this paper are publicly available at: ..作者: 眨眼 時(shí)間: 2025-3-24 19:08 作者: 暗諷 時(shí)間: 2025-3-25 02:16
Choosing, and Being, a Good Mentorf chokepoints on the growth rate is assessed on a number of metabolic networks. A software tool has been implemented to facilitate the computation of growth dependent chokepoints by the practitioners.作者: 聲音刺耳 時(shí)間: 2025-3-25 06:25
Stephanie S. Kim,Timothy R. Donahueat allow the control to be eventually released. Moreover, our method can incorporate information about the attractors to find new control strategies that would escape usual percolation-based methods. We show the applicability of our approach to two cell fate decision models.作者: 不整齊 時(shí)間: 2025-3-25 10:11 作者: Agronomy 時(shí)間: 2025-3-25 13:54 作者: inculpate 時(shí)間: 2025-3-25 18:52
Growth Dependent Computation of Chokepoints in Metabolic Networksf chokepoints on the growth rate is assessed on a number of metabolic networks. A software tool has been implemented to facilitate the computation of growth dependent chokepoints by the practitioners.作者: 結(jié)束 時(shí)間: 2025-3-25 20:33 作者: backdrop 時(shí)間: 2025-3-26 01:15
Qualitative Analysis of Mammalian Circadian Oscillations: Cycle Dynamics and Robustness provides a detailed view of the attractor, suggesting improvements in the design of the model’s logical rules and highlighting groups of transitions that are essential for the attractor’s robustness.作者: botany 時(shí)間: 2025-3-26 07:04
Core Models of Receptor Reactions to Evaluate Basic Pathway Designs Enabling Heterogeneous Commitmens the extent of biological heterogeneity observed .. Particularly, we focus on a positive feedback loop on caspase-8, the impacts of initial condition variations and the relevance of the caspase-8 degradation.作者: CEDE 時(shí)間: 2025-3-26 10:35 作者: paragon 時(shí)間: 2025-3-26 14:34
0302-9743 held in Konstanz, Germany, in September 2020.*.The 17 full papers and 5 tool papers were carefully reviewed and selected from 30 submissions. In addition 3 abstracts of invited talks and 2 tutorials have been included in this volume. Topics of interest include formalisms for modeling biological proc作者: Missile 時(shí)間: 2025-3-26 19:39
Conference proceedings 2020nstanz, Germany, in September 2020.*.The 17 full papers and 5 tool papers were carefully reviewed and selected from 30 submissions. In addition 3 abstracts of invited talks and 2 tutorials have been included in this volume. Topics of interest include formalisms for modeling biological processes; mod作者: CLAP 時(shí)間: 2025-3-26 23:17
Choosing, and Being, a Good Mentorximations can be automated. An implementation and example models are available online at .. We apply our techniques and tools to derive an expression for the mean velocity of a two-legged walker protein on DNA.作者: 聾子 時(shí)間: 2025-3-27 05:05
Jacob R. Peschman MD,Jon C. Gould MD can be then analysed using a fixed-point parameter synthesis algorithm to obtain all satisfying parametrisations. We evaluate the scalability of the method and demonstrate its applicability in a biological case study.作者: radiograph 時(shí)間: 2025-3-27 08:33 作者: 節(jié)約 時(shí)間: 2025-3-27 11:40
Parallel Parameter Synthesis for Multi-affine Hybrid Systems from Hybrid CTL Specifications can be then analysed using a fixed-point parameter synthesis algorithm to obtain all satisfying parametrisations. We evaluate the scalability of the method and demonstrate its applicability in a biological case study.作者: 變異 時(shí)間: 2025-3-27 17:17 作者: novelty 時(shí)間: 2025-3-27 20:24 作者: Mendacious 時(shí)間: 2025-3-27 23:39 作者: 取消 時(shí)間: 2025-3-28 04:50 作者: NOT 時(shí)間: 2025-3-28 10:17
https://doi.org/10.1007/978-3-030-60327-4artificial intelligence; bioinformatics; boolean networks; computer networks; correlation analysis; forma作者: 粉筆 時(shí)間: 2025-3-28 11:38
978-3-030-60326-7Springer Nature Switzerland AG 2020作者: 容易做 時(shí)間: 2025-3-28 14:58
Choosing, and Being, a Good Mentornguages and concurrency, and 2) mean field approximations (MFAs), a collection of approximation techniques ubiquitous in the study of complex dynamics. Using existing tools from algebraic graph rewriting, as well as new ones, we build a framework which generates rate equations for stochastic GTSs an作者: 傳染 時(shí)間: 2025-3-28 21:02
C. Max Schmidt M.D., Ph.D., MBA molecule fluctuates in time due to the random occurrence of production and degradation reactions. Here we consider a stochastic model for a self-regulating transcription factor whose lifespan (or time till degradation) follows a general distribution modelled as per a multi-dimensional phase-type pr作者: 名字 時(shí)間: 2025-3-29 00:56 作者: integral 時(shí)間: 2025-3-29 05:05
https://doi.org/10.1007/978-0-85729-313-8ation principles are abstracted away to focus on the main dynamical properties of the network structure. In their interpretation by ordinary differential equations, we say that a CRN with distinguished input and output species computes a positive real function ., if for any initial concentration . o作者: 晚來的提名 時(shí)間: 2025-3-29 07:47
Writing a Grant/Obtaining Funding When the variable is exactly constant, one talks about absolute concentration robustness (ACR). A dual and equally important property is ., which means that the system has multiple steady states and possible outputs, at constant parameters. We propose a new computational method based on interval te作者: Pulmonary-Veins 時(shí)間: 2025-3-29 14:47 作者: ureter 時(shí)間: 2025-3-29 17:45 作者: 品嘗你的人 時(shí)間: 2025-3-29 21:28 作者: 安定 時(shí)間: 2025-3-30 00:06 作者: 癡呆 時(shí)間: 2025-3-30 07:40
https://doi.org/10.1007/978-3-030-14644-3states and transitions. For biological systems, it becomes a challenging task to compare such mathematical objects with biological knowledge, or interpret the transitions inside an attractor in terms of the sequence of events in a biological cycle. A recent methodology generates summary graphs to he作者: 云狀 時(shí)間: 2025-3-30 08:53 作者: 主動(dòng)脈 時(shí)間: 2025-3-30 12:59 作者: Comedienne 時(shí)間: 2025-3-30 20:35
Success in Academic Surgery: Clinical Trialsnd tissue engineering. In this work, we study the control of biological networks, modelled as Boolean networks, to identify control paths driving the dynamics of the network from a source attractor (undesired cells) to the target attractor (desired cells). Instead of achieving the control in one ste作者: 撫慰 時(shí)間: 2025-3-30 23:55
Opportunities in Medical Student Education, which we observe through data and we model as parametrised continuous-time Markov Chains. The new approach simultaneously integrates learning models from data, done by likelihood-free Bayesian inference, specifically Approximate Bayesian Computation, with formal verification over models, done by st作者: 摘要 時(shí)間: 2025-3-31 04:33
