標(biāo)題: Titlebook: Computational Medicine; Tools and Challenges Zlatko Trajanoski Book 2012 Springer-Verlag Wien 2012 computational medicine [打印本頁] 作者: Taylor 時間: 2025-3-21 16:26
書目名稱Computational Medicine影響因子(影響力)
作者: nullify 時間: 2025-3-21 20:16
Book 2012l, two types of analyses for mass spectrometry data are reviewed: labeled quantitative proteomics and lipidomics, followed by protein sequence analysis and a 3D structure and drug design chapter. Finally, three chapters on clinical applications focus on the integration of biomolecular and clinical d作者: Cardioplegia 時間: 2025-3-22 02:38 作者: Cpr951 時間: 2025-3-22 05:59
High-Throughput Characterization and Comparison of Microbial Communities,nally, different sequencing approaches ahead of the bioinformatics analysis are considered. Furthermore, the application of microbiome analysis in medical research is shown by selected medical studies..The chapter is addressed to microbial ecologists or medical researchers without or little bioinfor作者: 高爾夫 時間: 2025-3-22 10:51
Lipidomics, Mass Spectrometry, and Bioinformatics,S data, with special emphasis on their applicability to available MS techniques. Furthermore, we discuss how the acquired measures for lipid abundance can be utilized for comparative purposes. Finally, we present both a brief overview of ongoing efforts in the establishment of a uniform lipid nomenc作者: 祖?zhèn)髫敭a(chǎn) 時間: 2025-3-22 12:53 作者: 祖?zhèn)髫敭a(chǎn) 時間: 2025-3-22 19:36 作者: Confound 時間: 2025-3-22 22:42
Competing Approaches in Economicsnally, different sequencing approaches ahead of the bioinformatics analysis are considered. Furthermore, the application of microbiome analysis in medical research is shown by selected medical studies..The chapter is addressed to microbial ecologists or medical researchers without or little bioinfor作者: 廣口瓶 時間: 2025-3-23 04:52
Jeremy Black,Donald M. MacRaildS data, with special emphasis on their applicability to available MS techniques. Furthermore, we discuss how the acquired measures for lipid abundance can be utilized for comparative purposes. Finally, we present both a brief overview of ongoing efforts in the establishment of a uniform lipid nomenc作者: 有特色 時間: 2025-3-23 05:34
Jeremy Black,Donald M. MacRaildom 3D structural data. Recently designed approaches for structure-based annotations, computational docking, 3D structure-based virtual screening, and interactome analysis are described, with particular accent on the advances over previous methods and on their intrinsic limitations. Few practical exa作者: myriad 時間: 2025-3-23 10:35
Zlatko TrajanoskiShows the connection from basic bioinformatics to application in biological as well as therapeutic questions.Gives insight into state-of-the-art IT solutions for application in medicine.Written by a e作者: Ambulatory 時間: 2025-3-23 17:10 作者: 必死 時間: 2025-3-23 20:44
https://doi.org/10.1007/978-0-230-21342-5cleotide polymorphisms (SNPs) and even large-scale genome resequencing. However, the inference of biological significance to association and mutation screening studies for complex diseases remains challenging and requires a sound knowledge about available bioinformatic data resources. The effects of作者: defuse 時間: 2025-3-23 23:19 作者: 圓錐 時間: 2025-3-24 03:25
Competing Approaches in Economicsn body are still poorly understood. The recent introduction of next-generation sequencing technologies allows for the first time an unbiased and in-depth characterization of a microbiome based on the sequence of certain marker genes. However, analysis of the huge amount of sequence data generated in作者: Interferons 時間: 2025-3-24 09:54 作者: Inflated 時間: 2025-3-24 11:52
Jeremy Black,Donald M. MacRailds spectrometers measure mass spectra of peptides on the basis of which software packages can infer protein detection. By tagging proteins from distinct samples with heavy and light mass labels, relative protein abundances in different conditions are compared, e.g., healthy versus diseased individual作者: fledged 時間: 2025-3-24 15:21
Jeremy Black,Donald M. MacRaildracting enormous interest in science, since it delivers information complementary to genomics and proteomics. This uptrend was triggered by progress in mass spectrometry; however, the burgeoning of lipidomics as a major area of research started relatively late compared to that of proteomics. A major作者: 抵消 時間: 2025-3-24 19:02
Jeremy Black,Donald M. MacRaildat can be translated into protein sequences. This review considers the different concepts applicable to sequence analysis and function prediction of globular and non-globular protein segments. The publicly accessible ANNOTATOR software environment integrates most of the reliable protein sequence-bas作者: Commonplace 時間: 2025-3-25 02:54 作者: Integrate 時間: 2025-3-25 06:12
Jeremy Black,Donald M. MacRaildht the various sources for generating data with specific focus on medium- and large-scale omics approaches as well as relevant public databases. We then give an overview of the computational methods necessary to analyze primary data as well as bioinformatics tools for using databases, extracting pat作者: 特征 時間: 2025-3-25 07:58 作者: 紅潤 時間: 2025-3-25 11:52
Longitudinal and Time-Series Analysis,conductor have emerged as a standard research environment to investigate and analyze high-throughput data. Therefore, we present and discuss existing packages, available in R or Bioconductor, that provide methods for . by means of networks. In particular, we summarize packages to reconstruct and ana作者: 劇毒 時間: 2025-3-25 17:50 作者: FUSC 時間: 2025-3-25 21:06 作者: 音樂戲劇 時間: 2025-3-26 01:47 作者: 的是兄弟 時間: 2025-3-26 05:48
Cloud Computing,etic laboratories to the limits of data storage and computational power. Therefore, new approaches are needed to eliminate these shortcomings and provide possibilities to use current algorithms in the area of bioinformatics with improved usability. A possible starting point is cloud computing with t作者: harmony 時間: 2025-3-26 08:34 作者: Presbycusis 時間: 2025-3-26 16:21
Microarray Meta-Analysis: From Data to Expression to Biological Relationships,gene function, regulation, and co-expression, to clinical use in diagnosis and prognosis. Over the last decade, a large number of microarray experiments have become available in public repositories often addressing similar or related hypotheses. The large compendia of gene expression data provide th作者: Fatten 時間: 2025-3-26 17:33 作者: Aspirin 時間: 2025-3-26 23:00
Lipidomics, Mass Spectrometry, and Bioinformatics,racting enormous interest in science, since it delivers information complementary to genomics and proteomics. This uptrend was triggered by progress in mass spectrometry; however, the burgeoning of lipidomics as a major area of research started relatively late compared to that of proteomics. A major作者: Bravura 時間: 2025-3-27 03:38
,Protein Sequence–Structure–Function–Network Links Discovered with the ANNOTATOR Software Suite: Appat can be translated into protein sequences. This review considers the different concepts applicable to sequence analysis and function prediction of globular and non-globular protein segments. The publicly accessible ANNOTATOR software environment integrates most of the reliable protein sequence-bas作者: 好開玩笑 時間: 2025-3-27 08:04
3D Structure and Drug Design,vel lead compounds and drugs and in the characterization of the biochemical mechanisms underlying the pharmacological and biological activity. Given that this information driven process is grounded on the experimental or computational determinations of the 3D structures, this chapter begins with a d作者: 直言不諱 時間: 2025-3-27 10:40
Integrating Biomolecular and Clinical Data for Cancer Research: Concepts and Challenges,ht the various sources for generating data with specific focus on medium- and large-scale omics approaches as well as relevant public databases. We then give an overview of the computational methods necessary to analyze primary data as well as bioinformatics tools for using databases, extracting pat作者: 痛打 時間: 2025-3-27 14:01
Applied Data Mining: From Biomarker Discovery to Decision Support Systems,tudy design consideration and bioanalytic concepts for generating biomedical data, followed by various data mining and information retrieval procedures such as feature selection, classification as well as statistical and clinical validation. The reviewed methods are illustrated by real examples from作者: 脾氣暴躁的人 時間: 2025-3-27 21:23
Network-Based Methods for Computational Diagnostics by Means of R,conductor have emerged as a standard research environment to investigate and analyze high-throughput data. Therefore, we present and discuss existing packages, available in R or Bioconductor, that provide methods for . by means of networks. In particular, we summarize packages to reconstruct and ana作者: 警告 時間: 2025-3-27 23:07
-art IT solutions for application in medicine.Written by a e.Computational methodologies and modeling play a growing role for investigating mechanisms, and for the diagnosis and therapy of human diseases. This progress gave rise to computational medicine, an interdisciplinary field at the interface 作者: 表被動 時間: 2025-3-28 05:05
Book 2012progress gave rise to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling as well as computational simulation techniques specifically 作者: lacrimal-gland 時間: 2025-3-28 07:55
,Protein Sequence–Structure–Function–Network Links Discovered with the ANNOTATOR Software Suite: Apped function prediction methods, protein domain databases and pathway, and protein–protein interaction collections developed in academia. As application example, the structural and functional domains of mel-28/ELYS, an important nuclear protein, are delineated and are proposed for experimental follow-up in structural biology and functional studies.作者: CESS 時間: 2025-3-28 10:36
Applied Data Mining: From Biomarker Discovery to Decision Support Systems, preclinical and clinical studies, and the application in medical decision making is discussed. This chapter is anticipated to address to those with a bioinformatics background as well as biomedical researchers who are interested in the application of computational methods in biomarker discovery and medical decision making.作者: 辯論 時間: 2025-3-28 17:53 作者: 集合 時間: 2025-3-28 21:41
Jeremy Black,Donald M. MacRaildwe discuss future challenges and suggest how a combined computational/experimental approaches can lead to new insights into the molecular mechanisms of cancer, and improved diagnosis and prognosis of the disease.作者: compel 時間: 2025-3-29 02:10 作者: 傻瓜 時間: 2025-3-29 05:24 作者: BIAS 時間: 2025-3-29 08:55
Jeremy Black,Donald M. MacRailded function prediction methods, protein domain databases and pathway, and protein–protein interaction collections developed in academia. As application example, the structural and functional domains of mel-28/ELYS, an important nuclear protein, are delineated and are proposed for experimental follow-up in structural biology and functional studies.作者: languid 時間: 2025-3-29 15:24
Experiments and Observational Studies, preclinical and clinical studies, and the application in medical decision making is discussed. This chapter is anticipated to address to those with a bioinformatics background as well as biomedical researchers who are interested in the application of computational methods in biomarker discovery and medical decision making.作者: preeclampsia 時間: 2025-3-29 18:45
