標(biāo)題: Titlebook: Computational Genome Analysis; An Introduction Richard C. Deonier,Michael S. Waterman,Simon Tavar Textbook 2005 Springer-Verlag New York 20 [打印本頁(yè)] 作者: advocate 時(shí)間: 2025-3-21 16:23
書目名稱Computational Genome Analysis影響因子(影響力)
作者: CROAK 時(shí)間: 2025-3-21 23:12
Textbook 2005us examples based upon the R statistics package..- Extensive descriptions and explanations to complement the analytical development..- More than 100 illustrations and diagrams (some in color) to reinforce concepts and present key results from the primary literature..- Exercises at the end of chapter作者: instill 時(shí)間: 2025-3-22 04:17
Words,of letters drawn from an alphabet, which in the case of DNA is the set of letters A, C, G, and T. A word of length . is called a “.-word” or “.-.”; we use these terms interchangeably. For example, individual bases are 1-tuples, dinucleotides are 2-tuples, and codons are triplets, or 3-tuples. GGGT is a 4-word or 4-tuple.作者: STIT 時(shí)間: 2025-3-22 06:19
Word Distributions and Occurrences, Today, given a genome sequence, we could design PCR primers flanking the DNA of interest and by PCR could amplify just that segment. Prior to the development of rapid genomic sequencing technologies, the process was much more complicated.作者: 損壞 時(shí)間: 2025-3-22 12:16 作者: 憤怒歷史 時(shí)間: 2025-3-22 15:27
https://doi.org/10.1007/0-387-28807-4Alignment; Analysis; DNA; algorithms; bioinformatics; clustering; computer; computer science; database; genom作者: 憤怒歷史 時(shí)間: 2025-3-22 17:05
978-1-4419-3162-7Springer-Verlag New York 2005作者: Flirtatious 時(shí)間: 2025-3-23 01:02 作者: 路標(biāo) 時(shí)間: 2025-3-23 04:46 作者: 揮舞 時(shí)間: 2025-3-23 05:32 作者: mucous-membrane 時(shí)間: 2025-3-23 09:47 作者: Conflict 時(shí)間: 2025-3-23 16:05 作者: Glucocorticoids 時(shí)間: 2025-3-23 21:27
Summary and Potential Applications Today, given a genome sequence, we could design PCR primers flanking the DNA of interest and by PCR could amplify just that segment. Prior to the development of rapid genomic sequencing technologies, the process was much more complicated.作者: nascent 時(shí)間: 2025-3-23 22:52 作者: 合乎習(xí)俗 時(shí)間: 2025-3-24 03:28
https://doi.org/10.1007/978-1-84996-030-4al pairs of linear chromosomes (humans have 23 pairs in each somatic cell), but prokaryotes typically have only one or a few circular (sometimes linear) chromosomes. The order of genes (or sets of genes) along a particular chromosome of a particular species is ordinarily conserved, and the list of g作者: genuine 時(shí)間: 2025-3-24 07:59
Summary and Potential Applicationseletal structures among tetrapods. The advent of protein and nucleic acid sequencing in molecular biology made possible comparison of organisms in terms of their DNA or the proteins that DNA encodes. These comparisons are important for a number of reasons. First, they can be used to establish evolut作者: 作嘔 時(shí)間: 2025-3-24 11:05
Summary and Potential Applicationsthe practicalities of the alignment process, and we demonstrate how it can be speeded up. The need for accelerated methods of alignment is connected with the potentially large number of possible alignments between two sequences (Section 6.5) and with the very large sizes of the databases that must b作者: floodgate 時(shí)間: 2025-3-24 18:27 作者: 馬籠頭 時(shí)間: 2025-3-24 20:40 作者: Dislocation 時(shí)間: 2025-3-25 00:24 作者: Paraplegia 時(shí)間: 2025-3-25 05:01
https://doi.org/10.1007/978-1-84996-030-4e for enzymes and other proteins involved in biochemical processes and their control. DNA in somatic cells is the same regardless of tissue type or physiological state. (Examples of human cells that . in DNA content are anucleate erythrocytes and gametes lacking either X or Y chromosomes.) Even thou作者: receptors 時(shí)間: 2025-3-25 10:12 作者: 胰臟 時(shí)間: 2025-3-25 13:37 作者: 受傷 時(shí)間: 2025-3-25 18:03
https://doi.org/10.1007/978-1-84996-030-4 phenotypes are determined by its genome sequence. In prior chapters, we presented a number of computational methods addressing a variety of specific biological questions. In this concluding chapter, we indicate in more detail how these tools can be employed in the context of complete genomes. Compu作者: APO 時(shí)間: 2025-3-25 21:32
Richard C. Deonier,Michael S. Waterman,Simon TavarDescribes the basic mathematics and statistics underlying computational genomics.Features free download of R software statistics package.Provides great crossover material that is interesting and acces作者: 衰老 時(shí)間: 2025-3-26 03:38
http://image.papertrans.cn/c/image/232321.jpg作者: CHASM 時(shí)間: 2025-3-26 05:00
Summary and Potential Applicationsof functionally conserved sequences (e.g., DNA sequences controlling gene expression). Finally, such comparisons between humans and other species may identify corresponding genes in model organisms, which can be genetically manipulated to develop models for human diseases.作者: 反復(fù)拉緊 時(shí)間: 2025-3-26 10:35
Summary and Potential Applicationssmid vectors. Obviously, experimental strategies are needed to convert a collection of sequences derived from large numbers of small inserts to the complete genome sequence. There have been two general approaches.作者: 是剝皮 時(shí)間: 2025-3-26 12:51
Summary and Potential Applications binding in the thermodynamic sense. This may be strong binding, as in the case of repressors binding to operators, or binding may be transient, as with restriction endonucleases. Examples of common signals in DNA are:作者: cataract 時(shí)間: 2025-3-26 18:35 作者: ineluctable 時(shí)間: 2025-3-26 23:29
Sequence Alignment,of functionally conserved sequences (e.g., DNA sequences controlling gene expression). Finally, such comparisons between humans and other species may identify corresponding genes in model organisms, which can be genetically manipulated to develop models for human diseases.作者: rectum 時(shí)間: 2025-3-27 04:20 作者: 仔細(xì)閱讀 時(shí)間: 2025-3-27 09:13
Signals in DNA, binding in the thermodynamic sense. This may be strong binding, as in the case of repressors binding to operators, or binding may be transient, as with restriction endonucleases. Examples of common signals in DNA are:作者: MOT 時(shí)間: 2025-3-27 12:03 作者: 懸掛 時(shí)間: 2025-3-27 16:56 作者: opinionated 時(shí)間: 2025-3-27 21:23
Similarity, Distance, and Clustering,chapter and will say a little more at the end of this chapter. For more extensive discussions of clustering and classification, see Dunn and Everitt (1982), Everitt and Dunn (2001), and Johnson and Wichern (2002).作者: 蚊子 時(shí)間: 2025-3-27 22:50 作者: Obituary 時(shí)間: 2025-3-28 05:00 作者: 存在主義 時(shí)間: 2025-3-28 10:00
Textbook 2005uses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book is appropriate for a one-semester course for advanced undergraduate or beginning graduate students, and it can also intro作者: 天氣 時(shí)間: 2025-3-28 12:14 作者: incontinence 時(shí)間: 2025-3-28 15:13 作者: Rodent 時(shí)間: 2025-3-28 21:18 作者: Nomadic 時(shí)間: 2025-3-28 23:14
Genome Rearrangements, example, even though the mouse (.) contains most of the same types of genes found in humans, the genetic map of the mouse differs from that of humans. This is illustrated in Fig. 5.1 for human (.) chromosome Hsa6, which contains blocks of DNA sequences corresponding to portions of six different mouse chromosomes.作者: 存在主義 時(shí)間: 2025-3-29 05:10 作者: apropos 時(shí)間: 2025-3-29 09:06
https://doi.org/10.1007/978-1-84996-030-4chapter and will say a little more at the end of this chapter. For more extensive discussions of clustering and classification, see Dunn and Everitt (1982), Everitt and Dunn (2001), and Johnson and Wichern (2002).作者: 陶瓷 時(shí)間: 2025-3-29 12:51 作者: flimsy 時(shí)間: 2025-3-29 16:27 作者: 直覺沒有 時(shí)間: 2025-3-29 22:21
vides great crossover material that is interesting and acces.Computational Genome Analysis: An Introduction presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the ma作者: 澄清 時(shí)間: 2025-3-30 01:16
Summary and Potential Applicationsith the potentially large number of possible alignments between two sequences (Section 6.5) and with the very large sizes of the databases that must be searched. Why is it necessary to search large databases?作者: progestogen 時(shí)間: 2025-3-30 07:17 作者: 貿(mào)易 時(shí)間: 2025-3-30 10:26
Biology in a Nutshell,biological organisms. The complete inventory of all DNA that determines the identity of an organism is called its .. Biological systems are complicated, interacting multivariate networks. They can be considered at a number of different levels, ranging from populations of organisms to molecules. At t作者: 外形 時(shí)間: 2025-3-30 13:04 作者: 組成 時(shí)間: 2025-3-30 18:17
Word Distributions and Occurrences, Today, given a genome sequence, we could design PCR primers flanking the DNA of interest and by PCR could amplify just that segment. Prior to the development of rapid genomic sequencing technologies, the process was much more complicated.作者: 減至最低 時(shí)間: 2025-3-30 21:39 作者: sed-rate 時(shí)間: 2025-3-31 01:24
Genome Rearrangements,al pairs of linear chromosomes (humans have 23 pairs in each somatic cell), but prokaryotes typically have only one or a few circular (sometimes linear) chromosomes. The order of genes (or sets of genes) along a particular chromosome of a particular species is ordinarily conserved, and the list of g作者: Delectable 時(shí)間: 2025-3-31 07:39 作者: 埋伏 時(shí)間: 2025-3-31 09:17
