標(biāo)題: Titlebook: Co-signal Molecules in T Cell Activation; Immune Regulation in Miyuki Azuma,Hideo Yagita Book 2019 Springer Nature Singapore Pte Ltd. 2019 [打印本頁] 作者: 故障 時(shí)間: 2025-3-21 19:49
書目名稱Co-signal Molecules in T Cell Activation影響因子(影響力)
書目名稱Co-signal Molecules in T Cell Activation影響因子(影響力)學(xué)科排名
書目名稱Co-signal Molecules in T Cell Activation網(wǎng)絡(luò)公開度
書目名稱Co-signal Molecules in T Cell Activation網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Co-signal Molecules in T Cell Activation被引頻次
書目名稱Co-signal Molecules in T Cell Activation被引頻次學(xué)科排名
書目名稱Co-signal Molecules in T Cell Activation年度引用
書目名稱Co-signal Molecules in T Cell Activation年度引用學(xué)科排名
書目名稱Co-signal Molecules in T Cell Activation讀者反饋
書目名稱Co-signal Molecules in T Cell Activation讀者反饋學(xué)科排名
作者: 哀求 時(shí)間: 2025-3-21 21:48 作者: 盟軍 時(shí)間: 2025-3-22 02:15 作者: 珊瑚 時(shí)間: 2025-3-22 05:56 作者: ARC 時(shí)間: 2025-3-22 09:26
Molecular Dynamics of Co-signal Molecules in T-Cell Activationgger the full activation signal. Co-stimulation receptors also accumulate, mostly at the TCR-MC, and induce signals that positively and negatively modulate the direction and magnitude of T-cell activation. CD28 initially colocalizes with the TCR-MC but then migrates to a distinct region of the cSMAC作者: JAMB 時(shí)間: 2025-3-22 15:40 作者: JAMB 時(shí)間: 2025-3-22 18:44 作者: debouch 時(shí)間: 2025-3-22 22:10 作者: extemporaneous 時(shí)間: 2025-3-23 05:25 作者: etidronate 時(shí)間: 2025-3-23 05:53 作者: 松緊帶 時(shí)間: 2025-3-23 12:47
Cancer Immunotherapy Targeting Co-signal Moleculesre is no doubt about an importance of co-signal molecules as one of the most promising targets in anti-cancer drugs. However, it should be noted that the proportion of patients who have objective and durable responses to immune checkpoint blockade remains less than 30% in majority of cancers. Thus, 作者: 設(shè)施 時(shí)間: 2025-3-23 17:07
https://doi.org/10.1007/978-3-030-51005-3doctrine. Since the discovery of CD28, a variety of co-signal molecules, including co-stimulatory and co-inhibitory receptors and ligands, have been identified. These molecules fine-tune various immune responses both in the primary or secondary lymphoid tissues and in the peripheral tissues. Most co作者: 菊花 時(shí)間: 2025-3-23 20:22 作者: podiatrist 時(shí)間: 2025-3-23 23:11 作者: 特征 時(shí)間: 2025-3-24 05:28 作者: 迅速飛過 時(shí)間: 2025-3-24 08:45
Majd Zouda,Tomo Nishizawa,Larry Benczegger the full activation signal. Co-stimulation receptors also accumulate, mostly at the TCR-MC, and induce signals that positively and negatively modulate the direction and magnitude of T-cell activation. CD28 initially colocalizes with the TCR-MC but then migrates to a distinct region of the cSMAC作者: Decibel 時(shí)間: 2025-3-24 14:10 作者: 改正 時(shí)間: 2025-3-24 16:14
Caroline Wehrmann,Ineke Henze–Rietveldon is derived from their ability to control and restrict the availability of co-signal molecules to other T cells. However, Tregs themselves also depend on many of the same co-signals for their own homeostasis, making this a complex system of feedback. In this chapter, we discuss the critical role o作者: formula 時(shí)間: 2025-3-24 19:49
Caroline Wehrmann,Ineke Henze–Rietveldtory and inhibitory co-signals. Among various co-receptors, those in the CD28/CTLA-4 family play fundamental roles in the regulation of lymphocytes by modulating the strength, quality, and/or duration of the antigen receptor signal. The development of the lethal lymphoproliferative disorder and vari作者: HPA533 時(shí)間: 2025-3-25 01:41
Science and Technology Governance and Ethicshly specialized environment where immune activation can be detrimental, it is crucial to understand mechanisms by which the immune system is regulated during neurological diseases. The system of co-signaling pathways provides the immune system with the means to fine-tune immune responses by turning 作者: 內(nèi)疚 時(shí)間: 2025-3-25 06:08 作者: Innocence 時(shí)間: 2025-3-25 11:08
Mazharul M. Islam,M. Moazzem Hossainre is no doubt about an importance of co-signal molecules as one of the most promising targets in anti-cancer drugs. However, it should be noted that the proportion of patients who have objective and durable responses to immune checkpoint blockade remains less than 30% in majority of cancers. Thus, 作者: 魔鬼在游行 時(shí)間: 2025-3-25 15:28 作者: 變異 時(shí)間: 2025-3-25 18:25 作者: 迅速飛過 時(shí)間: 2025-3-25 21:35
Control of Regulatory T Cells by Co-signal Moleculeson is derived from their ability to control and restrict the availability of co-signal molecules to other T cells. However, Tregs themselves also depend on many of the same co-signals for their own homeostasis, making this a complex system of feedback. In this chapter, we discuss the critical role of co-signaling in Treg cell biology.作者: 他很靈活 時(shí)間: 2025-3-26 01:45
https://doi.org/10.1007/978-981-32-9717-3Costimulation; Coinhibition; Immune Regulation; CD28; TNF-TNFR; T lymphocytes; Cancer Immunotherapy作者: HEDGE 時(shí)間: 2025-3-26 06:35
978-981-32-9719-7Springer Nature Singapore Pte Ltd. 2019作者: 文字 時(shí)間: 2025-3-26 10:45 作者: 容易做 時(shí)間: 2025-3-26 13:01
Caroline Wehrmann,Ineke Henze–Rietveldon is derived from their ability to control and restrict the availability of co-signal molecules to other T cells. However, Tregs themselves also depend on many of the same co-signals for their own homeostasis, making this a complex system of feedback. In this chapter, we discuss the critical role of co-signaling in Treg cell biology.作者: 摘要 時(shí)間: 2025-3-26 17:24 作者: MAZE 時(shí)間: 2025-3-26 23:55
Book 2019are explained and the future therapeutic potential in the aforementioned diseases is evaluated..Co-signal Molecules in?T Cell Activation?.will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.? ?.作者: creditor 時(shí)間: 2025-3-27 03:38 作者: 膽汁 時(shí)間: 2025-3-27 05:56
Challenges of Nuclear Power Production,e in the context of infection, inflammation, and cancer. We will also discuss how these TNFR co-signals are critical for immune regulation and have therapeutic potential for the treatment of T-cell-mediated diseases.作者: 漂浮 時(shí)間: 2025-3-27 10:11
Cultural Studies of Science Educationses, via recognition of a specific motif. Consequently, each co-stimulatory receptor transduces a unique pattern of signaling pathways. This review focuses on our current understanding of the intracellular signaling pathways provided by co-stimulatory and co-inhibitory molecules, including B7:CD28 f作者: BUMP 時(shí)間: 2025-3-27 17:22
Majd Zouda,Tomo Nishizawa,Larry Benczeoves to the cSMAC, CTLA-4 directly accumulates at the cSMAC. PD-1 inhibits activation by inducing dephosphorylation of TCR-upstream signaling molecules by transiently recruiting SHP2, whereas CTLA-4 competes with CD28 for CD80/86?binding within the signaling cSMAC. In general, for both positive and 作者: Nerve-Block 時(shí)間: 2025-3-27 21:00
Caroline Wehrmann,Ineke Henze–Rietveldlated adverse events of anti-CTLA-4 and anti-PD-1/PD-L1 therapies and the successful clinical application of the CD28 blocking therapy using CTLA-4-Ig to the treatment of arthritis assure their crucial roles in the regulation of autoimmunity in human. Accumulating evidences in mice and humans indica作者: overreach 時(shí)間: 2025-3-28 01:46
Science and Technology Governance and Ethicsy no drugs targeting these pathways have been successfully developed this far. Here, we will review the current literature on some important co-signaling pathways in multiple sclerosis (MS), Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and ischemic stroke to underst作者: endarterectomy 時(shí)間: 2025-3-28 04:22 作者: heartburn 時(shí)間: 2025-3-28 09:40 作者: 冒號 時(shí)間: 2025-3-28 12:16 作者: 創(chuàng)新 時(shí)間: 2025-3-28 15:22
Signal Transduction Via Co-stimulatory and Co-inhibitory Receptorsses, via recognition of a specific motif. Consequently, each co-stimulatory receptor transduces a unique pattern of signaling pathways. This review focuses on our current understanding of the intracellular signaling pathways provided by co-stimulatory and co-inhibitory molecules, including B7:CD28 f作者: Indurate 時(shí)間: 2025-3-28 18:50
Molecular Dynamics of Co-signal Molecules in T-Cell Activationoves to the cSMAC, CTLA-4 directly accumulates at the cSMAC. PD-1 inhibits activation by inducing dephosphorylation of TCR-upstream signaling molecules by transiently recruiting SHP2, whereas CTLA-4 competes with CD28 for CD80/86?binding within the signaling cSMAC. In general, for both positive and 作者: Oafishness 時(shí)間: 2025-3-29 02:51 作者: 精致 時(shí)間: 2025-3-29 05:41 作者: 組成 時(shí)間: 2025-3-29 10:24
Costimulation Blockade in Transplantation pathways can also lead to graft tolerance (Boenisch O, Sayegh MH, Najafian N, Curr Opin Organ Transplant 13:373–378, 2008). However, T-cell costimulation involves an incredibly complex array of interactions that may act simultaneously or at different times in the immune response and whose relative 作者: geriatrician 時(shí)間: 2025-3-29 15:23
Book 2019and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal mole作者: florid 時(shí)間: 2025-3-29 16:13
