標題: Titlebook: Clinical Trials of Antidepressants; How Changing the Mod Martin M. Katz Book 2016 The Author(s) 2016 depression.major depressive disorders. [打印本頁] 作者: otitis-externa 時間: 2025-3-21 19:21
書目名稱Clinical Trials of Antidepressants影響因子(影響力)
書目名稱Clinical Trials of Antidepressants影響因子(影響力)學科排名
書目名稱Clinical Trials of Antidepressants網(wǎng)絡公開度
書目名稱Clinical Trials of Antidepressants網(wǎng)絡公開度學科排名
書目名稱Clinical Trials of Antidepressants被引頻次
書目名稱Clinical Trials of Antidepressants被引頻次學科排名
書目名稱Clinical Trials of Antidepressants年度引用
書目名稱Clinical Trials of Antidepressants年度引用學科排名
書目名稱Clinical Trials of Antidepressants讀者反饋
書目名稱Clinical Trials of Antidepressants讀者反饋學科排名
作者: 僵硬 時間: 2025-3-22 00:10
Communications Satellite Serviceso not only achieve the primary aim of determining efficacy for a targeted disorder, but to extend results to encompass all clinical actions of the drug. It introduces the Multivantaged (MV) procedure as the methodological approach designed to enhance the amount of information from the standard trial.作者: characteristic 時間: 2025-3-22 04:08
M. A. Mayo,M. E. Taliansky,C. Fritschescribes the methods and the evidence leading to the generation of the three major dimensions and the 11 behavioral and mood components, their reliabilities and validities. It utilizes figures and tables from earlier research on their development.作者: 銀版照相 時間: 2025-3-22 08:29 作者: Brittle 時間: 2025-3-22 12:05
2192-8363 investigators, drug companies and patients.Includes suppleme.This brief guide takes current clinical trial protocols totask and replaces them with a contemporary framework for improvingnext-generation antidepressants and their underlying science. Innovative modelsare based on a nuanced, neurological作者: mercenary 時間: 2025-3-22 16:29
https://doi.org/10.5822/978-1-61091-581-6g the secondary aims. The chapter illustrates the importance of the secondary aims for advancing science in this area, generally. It highlights that limiting the goals of these inordinately expensive experiments to the efficacy of the trial drug for one targeted disorder, is deemed wasteful and shortsighted.作者: mercenary 時間: 2025-3-22 18:13 作者: Matrimony 時間: 2025-3-23 00:09 作者: Outshine 時間: 2025-3-23 02:22 作者: PAN 時間: 2025-3-23 07:56 作者: 送秋波 時間: 2025-3-23 11:37
Prediction and Shortening the Clinical Trial: Further Advantages of the Component-Specific Model,effective trial drugs for several weeks, and will markedly reduce costs to drug companies of the clinical trial itself. This evidence will hopefully stimulate more participation of companies in antidepressant drug development.作者: FLAT 時間: 2025-3-23 15:23
Introduction,s have occurred at great expense, leading to discouragement and diverting of industry to other issues. The chapter provides the rationale for why a new approach to evaluation in the trials is necessary.作者: venous-leak 時間: 2025-3-23 18:26 作者: commune 時間: 2025-3-23 22:25 作者: chronology 時間: 2025-3-24 05:25
,Achieving the “Ideal” Clinical Trial: An Example of Applying the Merged Componential and Establishe two week treatment results, and the nature of the component behavioral, mood and cognitive effects. It also, introduces the capacity afforded by the model to predict the outcome of the clinical trial, based on the two week results, opening the possibility of shortening future trials.作者: 歡樂東方 時間: 2025-3-24 09:41 作者: 寬宏大量 時間: 2025-3-24 11:11 作者: 口音在加重 時間: 2025-3-24 17:56
Why Now the Need for a New Clinical Trials Model for Antidepressants?,lier like assumptions to be wrong. When the new more comprehensive, componential trial is applied, it is also shown that new applications of the drug to the treatment of other disorders are uncovered.作者: 敘述 時間: 2025-3-24 21:10 作者: commute 時間: 2025-3-25 01:32 作者: Cryptic 時間: 2025-3-25 05:11 作者: Ataxia 時間: 2025-3-25 09:51 作者: 藐視 時間: 2025-3-25 13:26
Satellites of Other Celestial Bodies,te the increasing number of patients now diagnosed and seeking more effective treatment, and the fact that only one third can be successfully treated with the effective drugs. A major part of the problem is that no novel drugs have been developed during the past three decades, and many trial failure作者: faultfinder 時間: 2025-3-25 17:18
Satellites pour la navigation (GPS),tions about how and why the then new “antidepressants” were effective. These assumptions are described. They have assumed, e.g., that the drugs are specific for the depressive disorders. Based on research conducted since then, that assumption has been shown for the most part, to be invalid. The evid作者: delusion 時間: 2025-3-25 23:42 作者: Talkative 時間: 2025-3-26 01:53
Communications Satellite Servicesinduced clinical actions, not only changes produced in the overall severity of the disorder. The goal of achieving secondary aims is to render the trial a sound, scientific experiment, not merely, an applied exercise designed to determine overall efficacy. The new models are designed specifically, t作者: BIDE 時間: 2025-3-26 04:59
M. A. Mayo,M. E. Taliansky,C. Fritsch evaluated. Most of the assumptions are now shown to be invalid. The multivantaged method was developed to achieve both the primary and secondary aims of the trial. It provides the methods required to identify and measure the specific components and dimensions of the targeted disorder. The chapter d作者: 聽寫 時間: 2025-3-26 09:57
https://doi.org/10.1007/978-3-662-09796-0ided a good example of a “component-specific“ clinical trial. The results of that study are described demonstrating how the model works to achieve both the primary and secondary or profile of action results. The profile integrates the onset of clinical actions, the sequence, emphasizing the early or作者: Saline 時間: 2025-3-26 15:32
https://doi.org/10.5822/978-1-61091-581-6though both are equally strong in achieving the primary aim of evaluating overall efficacy, the established model has little to contribute to achieving the secondary aims. The chapter illustrates the importance of the secondary aims for advancing science in this area, generally. It highlights that l作者: 碌碌之人 時間: 2025-3-26 19:36 作者: 突變 時間: 2025-3-26 22:59
https://doi.org/10.1007/978-3-319-56774-7he Video Interview Behavior Evaluation Scales (VIBES), provides a videotaped standard interview, administered at baseline and weekly intervals during treatment, and a set of observational scales to measure symptomatic and physically expressive changes in behavior and mood. Advantages of videotaping 作者: BIDE 時間: 2025-3-27 04:22 作者: 為寵愛 時間: 2025-3-27 05:42 作者: adhesive 時間: 2025-3-27 12:10
https://doi.org/10.1007/978-3-319-56774-7d later actions of new drugs. Despite obvious strengths, it has limited usage due to problems associated with privacy of patient data. Where this can be overcome it can in future studies be a highly effective approach for the evaluation of new agents.作者: debouch 時間: 2025-3-27 14:49 作者: alabaster 時間: 2025-3-27 19:51 作者: wreathe 時間: 2025-3-27 22:51
Conclusions, uncovering of the applicability of the treatment to other mental disorders. The approaches, in addition offer the possibility of shortening trials to 2 to 3 weeks, resulting in markedly reducing costs and providing important relief and benefits to patients currently on ineffective treatments for ma作者: 水槽 時間: 2025-3-28 05:21 作者: 似少年 時間: 2025-3-28 07:59
Introduction,te the increasing number of patients now diagnosed and seeking more effective treatment, and the fact that only one third can be successfully treated with the effective drugs. A major part of the problem is that no novel drugs have been developed during the past three decades, and many trial failure作者: tattle 時間: 2025-3-28 12:15 作者: 死貓他燒焦 時間: 2025-3-28 15:42 作者: spondylosis 時間: 2025-3-28 20:55
Aims and Basic Requirements of Clinical Trials: Conventional and Component-Specific Models,induced clinical actions, not only changes produced in the overall severity of the disorder. The goal of achieving secondary aims is to render the trial a sound, scientific experiment, not merely, an applied exercise designed to determine overall efficacy. The new models are designed specifically, t作者: Basal-Ganglia 時間: 2025-3-29 00:34 作者: 存在主義 時間: 2025-3-29 04:35
,Achieving the “Ideal” Clinical Trial: An Example of Applying the Merged Componential and Establisheided a good example of a “component-specific“ clinical trial. The results of that study are described demonstrating how the model works to achieve both the primary and secondary or profile of action results. The profile integrates the onset of clinical actions, the sequence, emphasizing the early or作者: 寬度 時間: 2025-3-29 10:37
Comparing the Component-Specific Model Directly with the Established Diagnosis-Specific Trial,though both are equally strong in achieving the primary aim of evaluating overall efficacy, the established model has little to contribute to achieving the secondary aims. The chapter illustrates the importance of the secondary aims for advancing science in this area, generally. It highlights that l
