標(biāo)題: Titlebook: Clinical Proteomics; Methods and Protocol Fernando J. Corrales,Alberto Paradela,Miguel Marci Book 2022 The Editor(s) (if applicable) and Th [打印本頁] 作者: fibrous-plaque 時(shí)間: 2025-3-21 16:09
書目名稱Clinical Proteomics影響因子(影響力)
書目名稱Clinical Proteomics影響因子(影響力)學(xué)科排名
書目名稱Clinical Proteomics網(wǎng)絡(luò)公開度
書目名稱Clinical Proteomics網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Clinical Proteomics被引頻次
書目名稱Clinical Proteomics被引頻次學(xué)科排名
書目名稱Clinical Proteomics年度引用
書目名稱Clinical Proteomics年度引用學(xué)科排名
書目名稱Clinical Proteomics讀者反饋
書目名稱Clinical Proteomics讀者反饋學(xué)科排名
作者: 駕駛 時(shí)間: 2025-3-21 22:33
Lecture Notes in Mechanical Engineering approach, which includes a specific chemical acetylation reaction on unmodified lysine residues that carry heavy isotopes. The procedures described here have been applied to cell line cultures and to clinically relevant samples stored as both snap-frozen and formalin-fixed paraffin-embedded (FFPE) 作者: Affiliation 時(shí)間: 2025-3-22 03:12
Quality control and validation,ent diagnostic MS feature that allow the confidence of MS-based identifications. Our method is based on the concept of generation of hyper-citrullinated library with high-pH reversed-phase peptide fractionation that allows to enrich in low abundance citrullinated peptides and amplify the effect of c作者: jealousy 時(shí)間: 2025-3-22 04:38 作者: strain 時(shí)間: 2025-3-22 10:29 作者: 倔強(qiáng)不能 時(shí)間: 2025-3-22 13:59
1064-3745 nd practical, .Clinical Proteomics: Methods and Protocols. serves as an ideal guide for researchers working to expand upon the knowledge base needed to push forward toward a more personalized version of medicine..978-1-0716-1938-4978-1-0716-1936-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 倔強(qiáng)不能 時(shí)間: 2025-3-22 17:21 作者: 原始 時(shí)間: 2025-3-22 21:45 作者: 勤勞 時(shí)間: 2025-3-23 03:27
pH/Acetonitrile-Gradient Reversed-Phase Fractionation of Enriched Hyper-Citrullinated Library in Coent diagnostic MS feature that allow the confidence of MS-based identifications. Our method is based on the concept of generation of hyper-citrullinated library with high-pH reversed-phase peptide fractionation that allows to enrich in low abundance citrullinated peptides and amplify the effect of c作者: 實(shí)現(xiàn) 時(shí)間: 2025-3-23 08:06 作者: AWE 時(shí)間: 2025-3-23 13:22
Accurate Prediction of Protein Sequences for Proteogenomics Data Integration,-specific protein sequences that can be used as a drop-in replacement in existing approaches for peptide and protein identification using popular database search engines such as MSFragger, SearchGUI/PeptideShaker.作者: Minatory 時(shí)間: 2025-3-23 14:53
Fernando J. Corrales,Alberto Paradela,Miguel MarciIncludes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts作者: 真實(shí)的你 時(shí)間: 2025-3-23 21:40
Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/228185.jpg作者: 生命層 時(shí)間: 2025-3-23 22:38
https://doi.org/10.1007/978-1-0716-1936-0Precision medicine; Individual phenotypes; Disease progression; Therapeutic targets; Sample processing; T作者: Exposition 時(shí)間: 2025-3-24 03:49 作者: jabber 時(shí)間: 2025-3-24 08:09
Knud Kristensen,Elisabeth N?rbygaardterferent material is mandatory to achieve an ample proteome coverage by mass spectrometry. The study of biological fluids is always challenging due to their specific biochemical composition. However, there is increasing interest in their characterization as it will provide proteins that may advice 作者: 埋伏 時(shí)間: 2025-3-24 11:31 作者: Munificent 時(shí)間: 2025-3-24 18:50
Safety for Future Transport and Mobility mass tag labeling coupled with two-dimensional liquid chromatography and tandem mass spectrometry (TMT-LC/LC-MS/MS). Recently, we have established a robust method for direct profiling of undepleted cerebrospinal fluid (CSF) proteome with the 16-plex TMTpro method, in which we optimized parameters i作者: 開始發(fā)作 時(shí)間: 2025-3-24 20:48 作者: 惰性氣體 時(shí)間: 2025-3-25 02:19 作者: 似少年 時(shí)間: 2025-3-25 04:20 作者: 半導(dǎo)體 時(shí)間: 2025-3-25 09:13 作者: Melanoma 時(shí)間: 2025-3-25 11:57
https://doi.org/10.1007/978-94-011-4916-7nt disease areas including cancer. Precision medicine is most frequently based on the detection of genomic markers that correlate with the efficacy of selected targeted therapies. However, since nongenetic mechanisms also contribute to disease biology, there is a considerable interest of using prote作者: Endearing 時(shí)間: 2025-3-25 16:11
Quality control and validation,siological and pathological processes. Several methods to detect citrullinated proteins have been developed, including color development reagent, fluorescence, phenylglyoxal, and antibody-based methods. These methods yet suffer from limitations in sensitivity, specificity, or citrullinated site dete作者: 消散 時(shí)間: 2025-3-25 23:35 作者: forthy 時(shí)間: 2025-3-26 01:09 作者: HAWK 時(shí)間: 2025-3-26 05:17 作者: Dendritic-Cells 時(shí)間: 2025-3-26 12:24 作者: 饑荒 時(shí)間: 2025-3-26 14:48 作者: 粗俗人 時(shí)間: 2025-3-26 17:30 作者: 只有 時(shí)間: 2025-3-26 22:33 作者: 全面 時(shí)間: 2025-3-27 04:41
Philosophy of Advanced Interpretations mass spectrometry (XL-MS). EM (especially its cryogenic variant cryo-EM) has proven to be a very powerful tool for the structural determination of proteins and protein complexes, even at an atomic level. In a complementary way, XL-MS allows the precise characterization of particular interactions wh作者: 代理人 時(shí)間: 2025-3-27 08:45
https://doi.org/10.1007/978-94-009-0669-3of a living organism. Various aspects of genome variability affecting either the sequence or abundance level of proteins are discussed in this book chapter, such as the effect of single-nucleotide variants or larger genomic structural variants on the proteome. Next, various sequencing technologies a作者: 梯田 時(shí)間: 2025-3-27 11:50 作者: decode 時(shí)間: 2025-3-27 13:50
Clinical Proteomics978-1-0716-1936-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Osmosis 時(shí)間: 2025-3-27 18:23
Prediction of Shallow Gas from Seismic Datawhere it has become the reference method because it is simple, fast, and highly reproducible. We describe the different procedures used in the routine for pathogen identification using the Bruker MALDI Biotyper. system.作者: Bumptious 時(shí)間: 2025-3-27 23:32
Bile Processing Protocol for Improved Proteomic Analysis,terferent material is mandatory to achieve an ample proteome coverage by mass spectrometry. The study of biological fluids is always challenging due to their specific biochemical composition. However, there is increasing interest in their characterization as it will provide proteins that may advice 作者: Fissure 時(shí)間: 2025-3-28 02:21 作者: poliosis 時(shí)間: 2025-3-28 09:02 作者: LAVA 時(shí)間: 2025-3-28 12:44
Data-Independent Acquisition Mass Spectrometry-Based Deep Proteome Analysis for Hydrophobic Protein amounts in blood inhibit detection of other proteins in DBS by liquid chromatography-mass spectrometry (LC-MS/MS) without preenrichment. Sodium carbonate precipitation (SCP) can concentrate hydrophobic proteins from DBS and effectively remove soluble hydrophilic proteins. Furthermore, SCP combinati作者: 杠桿 時(shí)間: 2025-3-28 15:47 作者: 抵制 時(shí)間: 2025-3-28 21:40 作者: Fecal-Impaction 時(shí)間: 2025-3-29 01:47
Lysine Acetylation Stoichiometry Analysis at the Proteome Level,ical pathways are targets of this PTM. The lysine acetylation is a reversible modification controlled by two main groups of enzymes, lysine acetyltransferases responsible for transferring the acetyl group of acetylCoA to the side chain of lysine residues and lysine deacetylases which effectively rem作者: Somber 時(shí)間: 2025-3-29 04:31
Implementation of Clinical Phosphoproteomics and Proteomics for Personalized Medicine,nt disease areas including cancer. Precision medicine is most frequently based on the detection of genomic markers that correlate with the efficacy of selected targeted therapies. However, since nongenetic mechanisms also contribute to disease biology, there is a considerable interest of using prote作者: follicular-unit 時(shí)間: 2025-3-29 09:58 作者: 就職 時(shí)間: 2025-3-29 13:43 作者: 災(zāi)禍 時(shí)間: 2025-3-29 18:15
Generation of HLA Allele-Specific Spectral Libraries to Identify and Quantify Immunopeptidomes by Srred to as the immunopeptidome, is conducive to the success of a wide range of immunotherapies. The development of tools that enable the deconvolution of immunopeptidomes in the context of disease can help improve the specificity and effectiveness of therapeutic strategies targeting these peptides, 作者: 夸張 時(shí)間: 2025-3-29 22:10
Immunopeptidomic Analysis of the Phosphopeptidome Displayed by HLA Class I Molecules,s. In addition to conventional nonmodified peptides, these complex mixtures also contain phosphorylated species, which may be of great interest for personalized cancer immunotherapy. Here, we provide a detailed protocol to identify phosphopeptides displayed by human HLA class I molecules consisting 作者: CURL 時(shí)間: 2025-3-30 02:16
Development of a Standardized MRM Method for the Quantification of One Carbon Metabolism Enzymes, alkylating agent in living cells, and glutathione, their most important nonenzymatic antioxidant defense. Impairment of 1CM in hepatocytes is a recognized factor associated to chronic liver disorders and hepatocellular carcinoma. With this in mind, we have proposed the concept of functional biomark作者: Multiple 時(shí)間: 2025-3-30 06:47
Molecular Histology Analysis of Cryopreserved Tissue Using Peptide/Protein MALDI-TOF Imaging Mass Sion of peptides, small proteins, and other molecules within biological tissues. The obtained signals can be correlated with underlying tissue architecture, without any geometrical distortion, enabling the so-called molecular histology. Here, we analyzed cryopreserved tissue samples employing the MAL作者: 吸氣 時(shí)間: 2025-3-30 11:58
The Human Protein Atlas and Antibody-Based Tissue Profiling in Clinical Proteomics,in the intact tissue environment. Stringent procedures and proper antibody validation strategies are however needed to ensure reliability of results. Application-specific strategies have been proposed by the scientific community to ensure high quality despite variations in sample preparation between作者: 盲信者 時(shí)間: 2025-3-30 13:26
Microbial Identification in the Clinical Microbiology Laboratory Using MALDI-TOF-MS,where it has become the reference method because it is simple, fast, and highly reproducible. We describe the different procedures used in the routine for pathogen identification using the Bruker MALDI Biotyper. system.作者: BIBLE 時(shí)間: 2025-3-30 19:33 作者: 高度贊揚(yáng) 時(shí)間: 2025-3-30 20:49
Accurate Prediction of Protein Sequences for Proteogenomics Data Integration,of a living organism. Various aspects of genome variability affecting either the sequence or abundance level of proteins are discussed in this book chapter, such as the effect of single-nucleotide variants or larger genomic structural variants on the proteome. Next, various sequencing technologies a作者: ESPY 時(shí)間: 2025-3-31 03:16 作者: cavity 時(shí)間: 2025-3-31 08:40
Introduction to Occupational Safety, debris, and the second step in which microbial cells are broken up and microbiota proteins recovered for MS analysis. Detailed procedures for sample preparation, protein extraction, trypsin digestion, and mass spectrometry analysis for gut microbiota samples are provided.作者: BRAND 時(shí)間: 2025-3-31 10:38 作者: 血統(tǒng) 時(shí)間: 2025-3-31 16:32
MS-Based Extracellular Vesicle (EVs) Analysis: An Application to Helminth-Secreted EVs,ted by helminths, and describe a validated approach to characterize the proteins from different compartments of EVs. These proteins could be further developed into suitable diagnostic and vaccine candidates against these devastating infections.作者: CRAMP 時(shí)間: 2025-3-31 17:48
Sample Processing for Metaproteomic Analysis of Human Gut Microbiota, debris, and the second step in which microbial cells are broken up and microbiota proteins recovered for MS analysis. Detailed procedures for sample preparation, protein extraction, trypsin digestion, and mass spectrometry analysis for gut microbiota samples are provided.作者: Aerophagia 時(shí)間: 2025-3-31 23:33
Implementation of Clinical Phosphoproteomics and Proteomics for Personalized Medicine,teomic and phosphoproteomic analysis compatible with routine analysis of clinical samples. We also outline bioinformatic pipelines based on statistical learning that use these proteomics datasets as input to quantify kinase activities and predict drug responses in cancer cells.