標題: Titlebook: Clinical Pharmacology: Current Topics and Case Studies; Markus Müller (Professor and Head of Department) Book 20101st edition Springer-Ver [打印本頁] 作者: monster 時間: 2025-3-21 19:50
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書目名稱Clinical Pharmacology: Current Topics and Case Studies讀者反饋學科排名
作者: 帶子 時間: 2025-3-21 23:59 作者: 輕率看法 時間: 2025-3-22 03:19 作者: Control-Group 時間: 2025-3-22 07:32 作者: 水獺 時間: 2025-3-22 11:24 作者: 抵制 時間: 2025-3-22 16:19
Clinical trials - interventional studiest who conducted a trial with an appropriately controlled design from a modern point of view. In 1747 when scurvy was a common disease among sailors James Lind administered different acidic substances to 12 sailors affected with scurvy to test who benefits most. Five pairs of the seamen were given vi作者: 抵制 時間: 2025-3-22 17:47 作者: 著名 時間: 2025-3-22 22:26 作者: alcohol-abuse 時間: 2025-3-23 03:40
Pharmacokinetics II: 14C-labelled microdosing in assessing drug pharmacokinetics at Phase-0d at a microdose compared to a therapeutic dose has grown steadily. Based on current data in the public domain, there are 23 drugs where microdose and therapeutic dose pharmacokinetics can be compared. Of these, 84% scale within a factor of 2 for oral administration and 100% for intravenous administ作者: 共同時代 時間: 2025-3-23 09:33 作者: 幻想 時間: 2025-3-23 12:57 作者: Eulogy 時間: 2025-3-23 15:45
Current concepts of pharmacogenetics, pharmacogenomics, and the “druggable” genomelity can be translated into clinical practice. According to the current intriguing concepts of pharmacogenetics and pharmacogenomics, genetic information of individuals will be used to avoid “trial and error” scenarios during medication. Based on evidence from genomic testing, medicine is expected t作者: 是突襲 時間: 2025-3-23 20:56
Biomarkerstifying biological markers as indicators for an underlying disease is an elementary concept in medicine. Since the beginning of the medical skill of healing, signs and symptoms have been interpreted by medical doctors and guided diagnosis and treatment of their patients. With the emergence of the bi作者: BRAND 時間: 2025-3-24 01:00 作者: Albinism 時間: 2025-3-24 06:24 作者: mechanism 時間: 2025-3-24 06:36 作者: 集合 時間: 2025-3-24 14:22
Safe Filler Injection Techniquesronic diseases and the determination of number of patients affected by a disease, the latter being a cornerstone of public healthcare and preventive medicine. Epidemiological research provides a methodological basis for determination of factors involved in disease progression and risk.作者: DAFT 時間: 2025-3-24 17:56
Epidemiology and bio statisticsronic diseases and the determination of number of patients affected by a disease, the latter being a cornerstone of public healthcare and preventive medicine. Epidemiological research provides a methodological basis for determination of factors involved in disease progression and risk.作者: Project 時間: 2025-3-24 22:53
Andrew M. Dearden,Michael D. Harrison, (b) clinically, by administering appropriate drug therapy to patients and (c) within a regulatory framework, to provide guidance on the risk/benefit ratio of drug candidates in drug development and drug reimbursement.作者: defeatist 時間: 2025-3-25 00:38 作者: 同時發(fā)生 時間: 2025-3-25 04:54 作者: xanthelasma 時間: 2025-3-25 09:12 作者: Ingratiate 時間: 2025-3-25 15:14 作者: 陳腐的人 時間: 2025-3-25 18:19
Observational studies studies seemed to gradually displace observational research in the field of clinical pharmacology, because they permitted fair comparisons at much higher levels of internal validity. An important breakthrough of this concept was seen after Archie Cochrane had published his very influential book on effectiveness and efficiency in 1972 [2].作者: 樹膠 時間: 2025-3-25 21:33 作者: humectant 時間: 2025-3-26 01:30
Tools in clinical pharmacology - imaging techniquesetic resonance imaging (MRI), X-ray computed tomography (CT) or ultrasound imaging. Furthermore there is the up-and-coming possibility to combine different imaging modalities such as PET/CT, SPECT/CT, and MRI/PET in order to match functional to anatomical information.作者: 輕浮女 時間: 2025-3-26 07:47 作者: 凹處 時間: 2025-3-26 11:21
Safe Filler Injection Techniques. In general, drug development is ideally a step-wise procedure in which information gained from early, typically smaller, studies is used to plan and perform larger studies with more detailed objectives.作者: 細胞學 時間: 2025-3-26 13:03
https://doi.org/10.1007/978-94-6091-936-7r clinical decision making emerged as they were correlated with the pathology and the clinical course of disease states. This “traditional identification” of biomarkers as an observational site product of clinical practice led to the identification of the majority of clinical biomarkers employed in clinical practice today.作者: 橢圓 時間: 2025-3-26 19:07
Phase-I studies and first-in-human trials. In general, drug development is ideally a step-wise procedure in which information gained from early, typically smaller, studies is used to plan and perform larger studies with more detailed objectives.作者: Nibble 時間: 2025-3-26 21:09 作者: morale 時間: 2025-3-27 01:52 作者: Armory 時間: 2025-3-27 05:22
Peter A. Lindsay,John A. McDermid a large number of powerful drugs which were rapidly developed by industry in response to the challenge posed by the HIV pandemic, success rates in (2) are determined by the discovery of an entirely new and/or previously overlooked concept for the pathogenesis of gastric diseases, i.e. a Helicobacte作者: SMART 時間: 2025-3-27 09:52 作者: Fecal-Impaction 時間: 2025-3-27 16:01
Safe Filler Injection Techniquesifferent stages of drug discovery, which can also be applied in the drug development process. PK-PD relationships can be expressed by numerous mathematical models which have been increasingly demonstrated to be predictive of therapeutic outcomes during the development process. The PK-PD modelling an作者: ELUDE 時間: 2025-3-27 19:21 作者: 使困惑 時間: 2025-3-28 00:32 作者: 官僚統(tǒng)治 時間: 2025-3-28 02:44
Clinical Pharmacology: Current Topics and Case Studies作者: alcohol-abuse 時間: 2025-3-28 06:37 作者: 即席 時間: 2025-3-28 10:44
y but also provides insight in current topics like genomics, imaging technology and issues in drug reimbursement. A number of concrete case studies in clinical drug research and development help to give a better understanding of the general principles of CP. .978-3-7091-0144-5作者: 組成 時間: 2025-3-28 17:27
Current issues in drug development a large number of powerful drugs which were rapidly developed by industry in response to the challenge posed by the HIV pandemic, success rates in (2) are determined by the discovery of an entirely new and/or previously overlooked concept for the pathogenesis of gastric diseases, i.e. a Helicobacte作者: nitroglycerin 時間: 2025-3-28 21:35 作者: 晚來的提名 時間: 2025-3-29 01:12 作者: Limpid 時間: 2025-3-29 05:42
Current concepts of pharmacogenetics, pharmacogenomics, and the “druggable” genome still lie ahead until genomic medicine will become routine clinical practice. In this chapter, important facts of the principles in genomic medicine are summarized, providing insight into ways how genetic information of an individual can be used to improve drug safety and efficacy, and further can 作者: COMA 時間: 2025-3-29 08:25
Andrew M. Dearden,Michael D. Harrisondern therapeutics” and that “drug therapy varies widely among individuals” [1]. These two statements set the stage for the discipline of Clinical Pharmacology (CP) which pursues two main goals: (1) an empirical description of conditions under which drug actions vary in humans and (2) to determine an作者: paltry 時間: 2025-3-29 13:24
Peter A. Lindsay,John A. McDermides, most notably infections, have extremely satisfying therapeutic success rates and many serious diseases like diabetes mellitus or some forms of cancer have become chronic, stable diseases and do not lead to extreme shortages of life years any longer. Prime examples for success stories in drug dev作者: Dorsal 時間: 2025-3-29 19:32
Peter A. Lindsay,John A. McDermidjectives: first, into an obligation to protect patients against ineffective or harmful drugs, and second, to protect patients against the consequences of untreated disease. The first objective results in a gatekeeper function and obliges regulators to apply stringent standards of assessment and to d作者: 商談 時間: 2025-3-29 21:01
Xun Yi,Kwork-Yan Lam,Yong-Fei Han“Beveridge Systems”, by private health insurance providers, or by independent, non-profit statutory institutions - the so-called “Bismarck” system [1, 2]. Notably, this has also been the case for Medicare in the USA due to the Medicare Prescription Drug Improvement and Modernization Act, which was p作者: BRIDE 時間: 2025-3-30 02:44 作者: 馬具 時間: 2025-3-30 05:42 作者: 突襲 時間: 2025-3-30 11:44 作者: ANTIC 時間: 2025-3-30 14:22
Safe Filler Injection Techniquesion, and complexity or severity of infection. Therapeutic response to an anti-infective agent or its pharmacological effect is often associated with high variability in clinical situations. Pharmacokinetics (PK) and pharmacodynamics (PD) contribute to a better understanding of the relationship betwe作者: 步履蹣跚 時間: 2025-3-30 17:55 作者: extinguish 時間: 2025-3-30 21:56
Safe Filler Injection Techniquescent years the scope of epidemiological research has become much boarder, including the research for optimal treatment approaches in both acute and chronic diseases and the determination of number of patients affected by a disease, the latter being a cornerstone of public healthcare and preventive m作者: 容易生皺紋 時間: 2025-3-31 03:04
Safe Clavicle Fracture Surgery,either functional or anatomical modalities. Functional modalities are capable of visualizing biological processes within organs or tissues at a molecular level. Positron emission tomography (PET) and single photon emission computed tomography (SPECT) are well established tools, whereas optical imagi作者: 自由職業(yè)者 時間: 2025-3-31 07:57 作者: 鼓掌 時間: 2025-3-31 12:52 作者: Deduct 時間: 2025-3-31 14:32
Markus Müller (Professor and Head of Department)Comprehensive overview of current topics in clinical pharmacology.Case studies for every issue.Added value for employees in drug research and development作者: fetter 時間: 2025-3-31 18:10
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