標(biāo)題: Titlebook: Clinical Epidemiology; Practice and Methods Patrick S. Parfrey,Brendan J. Barrett Book 2021Latest edition Springer Science+Business Media, [打印本頁] 作者: 從未迷惑 時間: 2025-3-21 19:13
書目名稱Clinical Epidemiology影響因子(影響力)
作者: 自戀 時間: 2025-3-21 21:19
Book 2021Latest editionular Biology. series format, chapters include introductions to their respective topics, lists of various types of bias, step-by-step, readily reproducible protocols for different research designs, and tips on troubleshooting and avoiding known pitfalls..Cutting-edge and thorough, .Clinical Epidemiol作者: Measured 時間: 2025-3-22 02:06
M. Colacino,E. Piervitali,P. Grigionitific research team might incorporate a strong and effective ELSI program within its broader research mandate. We begin by describing the historical context of ELSI research and the development of GE.LS research in the Canadian context. We then illustrate how some ELSI research might unfold by outli作者: indigenous 時間: 2025-3-22 08:32
Hermann Suida,Heinrich Salvaterrans. The domain coverage of commonly used generic short forms varies substantially. Individualized measurement of quality of life is possible, but resource intensive. Focus groups are useful, not only for scale development but also to confirm the appropriateness of existing instruments..Under classic作者: OWL 時間: 2025-3-22 11:57
https://doi.org/10.1007/978-3-322-96002-3effects with smaller sample sizes. However, to be useful, surrogate outcomes have to be validated to ensure that the effect of therapy on them truly reflects the effect of therapy on the important clinical outcomes of interest.作者: 花束 時間: 2025-3-22 15:31
Physiology of Nonpulsatile Circulationcs and epidemiology, which historically have functioned separately, have been integrated into a hybrid discipline referred to as genetic epidemiology. In this chapter, we review methods for establishing the genetic burden of complex genetic disease, followed by methods for gene and/or genetic varian作者: 花束 時間: 2025-3-22 18:31
Ethical, Legal, and Social Issues (ELSI) in Clinical Genetics Research,tific research team might incorporate a strong and effective ELSI program within its broader research mandate. We begin by describing the historical context of ELSI research and the development of GE.LS research in the Canadian context. We then illustrate how some ELSI research might unfold by outli作者: paragon 時間: 2025-3-22 23:01 作者: 憎惡 時間: 2025-3-23 02:22 作者: NOT 時間: 2025-3-23 08:32
Genetic Epidemiology of Complex Phenotypes,cs and epidemiology, which historically have functioned separately, have been integrated into a hybrid discipline referred to as genetic epidemiology. In this chapter, we review methods for establishing the genetic burden of complex genetic disease, followed by methods for gene and/or genetic varian作者: 深淵 時間: 2025-3-23 09:49 作者: Optic-Disk 時間: 2025-3-23 17:01 作者: muffler 時間: 2025-3-23 20:13
Hermann Suida,Heinrich Salvaterrassments in trials. Therefore, familiarity with the strategies used to account for missing data is necessary. Measures that incorporate both survival and QoL are helpful for treatment decisions. The definition of minimal clinically important differences in QoL scores is important and often derived using inadequate methods.作者: Kidnap 時間: 2025-3-23 23:45
Randomized Controlled Trials 2: Analysis,nd stopping rules, mortality comparisons, composite outcomes, research design including run-in periods, factorial, stratified and crossover designs, number needed to treat, power issues, multivariate modeling, subgroup analysis, competing risks, and hypothesis-generating analyses.作者: florid 時間: 2025-3-24 03:10
Randomized Controlled Trials 4: Planning, Analysis, and Interpretation of Quality-of-Life Studies,ssments in trials. Therefore, familiarity with the strategies used to account for missing data is necessary. Measures that incorporate both survival and QoL are helpful for treatment decisions. The definition of minimal clinically important differences in QoL scores is important and often derived using inadequate methods.作者: 遣返回國 時間: 2025-3-24 07:10
Book 2021Latest editionmaking, and a new section on changing health-related behaviors. The chapters in this book are organized into six parts: Part One focuses on framing clinical research questions and choosing a suitable design; biases that may occur in clinical research; and the ethics associated with doing conducting 作者: 飾帶 時間: 2025-3-24 13:57
https://doi.org/10.1007/978-1-349-09381-6stical relevance. The hierarchy of evidence for clinical decision-making places randomized controlled trials (RCT) or systematic review of good-quality RCTs at the top of the evidence pyramid. Prognostic and etiologic questions are best addressed with longitudinal cohort studies.作者: 附錄 時間: 2025-3-24 17:21 作者: Alcove 時間: 2025-3-24 20:44 作者: 初次登臺 時間: 2025-3-25 03:13
Mikhail V. Nezlin,Evgenii N. Snezhkinzed in the effect estimates (model coefficients). The error element of the model represents the variability in the data unexplained by the model and is used to build measures of precisions around the point estimates (Confidence Intervals).作者: bonnet 時間: 2025-3-25 05:22 作者: manifestation 時間: 2025-3-25 11:18
Physiology of Nonpulsatile Circulationitive and negative tests, and receiver operating characteristic (ROC) curves. The role of the test in a diagnostic pathway has then to be determined, following which the effect on patient outcome should be examined.作者: 蛛絲 時間: 2025-3-25 15:02
On Framing the Research Question and Choosing the Appropriate Research Design,stical relevance. The hierarchy of evidence for clinical decision-making places randomized controlled trials (RCT) or systematic review of good-quality RCTs at the top of the evidence pyramid. Prognostic and etiologic questions are best addressed with longitudinal cohort studies.作者: 過去分詞 時間: 2025-3-25 17:54
Research Ethics for Clinical Researchers,ss of informed consent, and step-by-step practical guidelines are described. The issue of inclusivity in research is touched upon, and suggestions are provided. Practical advice is provided for researchers to guide their interactions with research ethics boards.作者: 催眠藥 時間: 2025-3-25 20:06
Longitudinal Studies 1: Determinants of Risk,founders are present, and specific studies designs have their own inherent forms of bias. Careful study design may minimize bias. Establishing casual association based on observational methods requires due consideration of the quality of the individual study and knowledge of their limitations.作者: 免費(fèi) 時間: 2025-3-26 03:19 作者: spondylosis 時間: 2025-3-26 06:27
Longitudinal Studies 3: Data Modeling Using Standard Regression Models and Extensions,e subjects or group of subjects, observations are not independent and the underlying correlation needs to be addressed in the analysis. In these circumstances, extended models are necessary to handle complexities related to clustered data, and repeated measurements of time-varying predictors and/or outcomes.作者: 戲服 時間: 2025-3-26 10:20 作者: glamor 時間: 2025-3-26 15:34
https://doi.org/10.1007/978-1-349-09381-6he types of bias that exist and also to be able to assess their impact on the magnitude and direction of the observed effect. The following chapter reviews the epidemiological concepts of selection bias, information bias, intervention bias, and confounding and discusses ways in which these sources of bias can be minimized.作者: 單獨(dú) 時間: 2025-3-26 17:19 作者: Corral 時間: 2025-3-26 23:45
Basic Design Criteria for Rotary Blood Pumps(IPCW), accelerated failure time models, and contamination adjusted intent-to-treat analysis. These methods are particularly useful in assessing the “prescribed efficacy” of the study treatment, which can aid clinical decision-making.作者: 強(qiáng)有力 時間: 2025-3-27 03:45 作者: diathermy 時間: 2025-3-27 05:48 作者: LASH 時間: 2025-3-27 09:46 作者: REIGN 時間: 2025-3-27 15:19
Der Angriff des Eisens in Elektrolyten,scribes the major principles of matching applied to case–control, cohort, and propensity score studies. Matched study designs provide several advantages for controlling confounding in observational studies; however, they remain vulnerable to residual confounding, and can even introduce bias when implemented incorrectly.作者: 個人長篇演說 時間: 2025-3-27 18:34
Der Wasserstoffgehalt des Eisens,urrent chapter, we describe the general approach to developing a risk prediction model. We then illustrate how these methods are applied in the development and validation of the kidney failure risk equation (KFRE), which accurately predicts the risk of kidney failure in patients with chronic kidney disease stages 3–5.作者: 沒血色 時間: 2025-3-28 01:10 作者: obsession 時間: 2025-3-28 05:57
Longitudinal Studies 4: Matching Strategies to Evaluate Risk,scribes the major principles of matching applied to case–control, cohort, and propensity score studies. Matched study designs provide several advantages for controlling confounding in observational studies; however, they remain vulnerable to residual confounding, and can even introduce bias when implemented incorrectly.作者: 膠水 時間: 2025-3-28 08:16
Longitudinal Studies 5: Development of Risk Prediction Models for Patients with Chronic Disease,urrent chapter, we describe the general approach to developing a risk prediction model. We then illustrate how these methods are applied in the development and validation of the kidney failure risk equation (KFRE), which accurately predicts the risk of kidney failure in patients with chronic kidney disease stages 3–5.作者: 替代品 時間: 2025-3-28 13:25
Randomized Controlled Trials 1: Design,sed to ensure the proper application of epidemiological principles resulting in clinical studies that are feasible and generalizable. In addition, funding strategies and trial team composition are discussed.作者: Munificent 時間: 2025-3-28 16:25 作者: Hearten 時間: 2025-3-28 21:26
Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/227932.jpg作者: Resistance 時間: 2025-3-29 02:49 作者: 切割 時間: 2025-3-29 05:20
https://doi.org/10.1007/978-3-030-60720-3assified by stage of research: literature review and publication, design of the study and selection of subjects, execution of the intervention, measurement of exposures and outcomes, data analysis, and interpretation and publication. Definitions are provided for each type of bias listed.作者: 星星 時間: 2025-3-29 10:22
https://doi.org/10.1007/978-1-0716-1138-8clinical genetics; Biomarkers; prediction models; Translational research; ; ethics作者: Pcos971 時間: 2025-3-29 11:31 作者: Indigence 時間: 2025-3-29 17:41
https://doi.org/10.1007/978-1-349-09381-6e question requires definition of patients, interventions, controls, and outcomes. The goal of research design is to minimize error, ensure adequate samples, measure input and output variables appropriately, consider external and internal validities, limit bias, and address clinical as well as stati作者: 充氣女 時間: 2025-3-29 22:15
https://doi.org/10.1007/978-1-349-09381-6tive measures or treatments, the analysis of the risks and benefits of diagnostic and therapeutic maneuvers, and the evaluation of health care services. In all areas, the main focus is to describe the relationship between exposure and outcome and to determine one of the following: prevalence, incide作者: 注意 時間: 2025-3-30 03:28
https://doi.org/10.1007/978-3-030-60720-3assified by stage of research: literature review and publication, design of the study and selection of subjects, execution of the intervention, measurement of exposures and outcomes, data analysis, and interpretation and publication. Definitions are provided for each type of bias listed.作者: Lignans 時間: 2025-3-30 06:36 作者: COMA 時間: 2025-3-30 11:00
M. Colacino,E. Piervitali,P. Grigioni various impacts of science and technology on society. In Canada, GE.LS (Genetics, Ethical, Economic, Environmental, Legal, Social issues) is the term used to describe ELSI studies in the context of genetics and genomics research. It is intentionally more expansive in that GE.LS explicitly brings ec作者: Gyrate 時間: 2025-3-30 13:11 作者: ostracize 時間: 2025-3-30 20:18 作者: 手術(shù)刀 時間: 2025-3-30 22:29
Mikhail V. Nezlin,Evgenii N. Snezhkinme. Traditional regression techniques are used to model outcome data when each epidemiological unit is observed once. These models include generalized linear models for quantitative continuous, discrete, or qualitative outcome responses, and models for time-to-event data. When data come from the sam作者: 寬宏大量 時間: 2025-3-31 01:11 作者: Meager 時間: 2025-3-31 06:49 作者: DRAFT 時間: 2025-3-31 10:02 作者: 針葉樹 時間: 2025-3-31 13:33 作者: Fortify 時間: 2025-3-31 20:00 作者: 注意到 時間: 2025-4-1 01:27 作者: 教育學(xué) 時間: 2025-4-1 03:18 作者: 我沒有命令 時間: 2025-4-1 07:10
https://doi.org/10.1007/978-3-322-96002-3ssure that statistical power is sufficiently high when the probability of falsely rejecting a true null hypothesis (type I error) is kept acceptably small. This chapter overviews the fundamental of sample size calculation for standard types of outcomes for 2-group studies. It also considers (1) the
