標(biāo)題: Titlebook: Clinical Applications of Mass Spectrometry in Drug Analysis; Methods and Protocol Uttam Garg Book 2024Latest edition The Children?s Mercy H [打印本頁(yè)] 作者: Washington 時(shí)間: 2025-3-21 17:36
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書目名稱Clinical Applications of Mass Spectrometry in Drug Analysis影響因子(影響力)學(xué)科排名
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書目名稱Clinical Applications of Mass Spectrometry in Drug Analysis網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書目名稱Clinical Applications of Mass Spectrometry in Drug Analysis被引頻次
書目名稱Clinical Applications of Mass Spectrometry in Drug Analysis被引頻次學(xué)科排名
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書目名稱Clinical Applications of Mass Spectrometry in Drug Analysis年度引用學(xué)科排名
書目名稱Clinical Applications of Mass Spectrometry in Drug Analysis讀者反饋
書目名稱Clinical Applications of Mass Spectrometry in Drug Analysis讀者反饋學(xué)科排名
作者: 吵鬧 時(shí)間: 2025-3-21 23:54 作者: 暴發(fā)戶 時(shí)間: 2025-3-22 00:51 作者: dictator 時(shí)間: 2025-3-22 04:50 作者: tic-douloureux 時(shí)間: 2025-3-22 09:48 作者: 圖表證明 時(shí)間: 2025-3-22 16:34 作者: 圖表證明 時(shí)間: 2025-3-22 20:59
Inszenierung und Kontingenz: Fallstudien,cted from plasma with methanol containing deuterated internal standards. Turbulent flow chromatography coupled with reversed-phase HPLC was used for separation, while the mass spectrometer was set in the positive ion mode. This method has proven accurate and rapid and allowed for timely dose adjustm作者: labile 時(shí)間: 2025-3-22 23:33 作者: profligate 時(shí)間: 2025-3-23 01:42 作者: disrupt 時(shí)間: 2025-3-23 06:08 作者: Vertebra 時(shí)間: 2025-3-23 10:48
Mass Spectrometry in Clinical Laboratory: Applications in Therapeutic Drug Monitoring and Toxicologo present “off-the-shelf” and “ready-to-use” protocols of recent developments in new assays to help the clinical laboratory community adopt the technology and analysis for the betterment of patient care.作者: 好色 時(shí)間: 2025-3-23 17:50
Quantitative LC-MS/MS Analysis of Amphetamines and Cocaine in Human Urine,t response for each analyte at a given concentration is normalized against stable isotope-labeled internal standard. In addition, the assay can be multiplexed across more than one LC channel to obtain high-sample throughput.作者: 過(guò)于光澤 時(shí)間: 2025-3-23 21:04
Quantitative LC-MS/MS Method for the Simultaneous Measurement of Six Antiepileptics and Pentobarbittopiramate, zonisamide) and that of pentobarbital by LC-MS/MS. Liquid-liquid sample extraction is followed by reversed-phase chromatography using biphenyl HPLC column and gradient elution. Two MRM transitions are monitored for each drug, and their heavy isotope labeled internal standards. Six-point 作者: OATH 時(shí)間: 2025-3-24 00:33
Analysis of Barbiturates in Urine by LC-MS/MS, method helps gain efficiency in a high-volume laboratory environment. Additional features of this protocol that help in efficiency gain are automated extraction using Hamilton? liquid handling system and algorithmic data review using Ascent? software.作者: 邊緣帶來(lái)墨水 時(shí)間: 2025-3-24 03:39 作者: infatuation 時(shí)間: 2025-3-24 07:49 作者: Resistance 時(shí)間: 2025-3-24 13:04
Determination of Busulfan and Melphalan in Plasma by Turbulent Flow Chromatography-Tandem Mass Speccted from plasma with methanol containing deuterated internal standards. Turbulent flow chromatography coupled with reversed-phase HPLC was used for separation, while the mass spectrometer was set in the positive ion mode. This method has proven accurate and rapid and allowed for timely dose adjustm作者: WAX 時(shí)間: 2025-3-24 15:56 作者: 經(jīng)典 時(shí)間: 2025-3-24 21:18
https://doi.org/10.1007/3-7908-1668-Xwith a bias of ?0.2–5%. The intra- and inter-day imprecision were less than 5.0% for all the analytes. The linear assay ranges were 0.3–26?μg/mL for GPN, 0.15–24?μg/mL for LCM, 7.4–1881?ng/mL for PER, 0.03–13?μg/mL for PRG, 0.78–90?μg/mL for RFM, and 0.3–43?μg/mL for VGB.作者: 珊瑚 時(shí)間: 2025-3-25 00:59 作者: 語(yǔ)源學(xué) 時(shí)間: 2025-3-25 03:21
Developments in Cardiovascular Medicinentent from each patient-derived plasma sample. After completing a second stage of sample dilution (5000-fold overall), a 2 μL volume?of the plasma extract is analyzed using the liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based bioanalytical method described.作者: 威脅你 時(shí)間: 2025-3-25 09:41 作者: Friction 時(shí)間: 2025-3-25 12:33
Quantification of Gabapentin, Lacosamide, Perampanel, Pregabalin, Rufinamide, and Vigabatrin in Serwith a bias of ?0.2–5%. The intra- and inter-day imprecision were less than 5.0% for all the analytes. The linear assay ranges were 0.3–26?μg/mL for GPN, 0.15–24?μg/mL for LCM, 7.4–1881?ng/mL for PER, 0.03–13?μg/mL for PRG, 0.78–90?μg/mL for RFM, and 0.3–43?μg/mL for VGB.作者: nutrition 時(shí)間: 2025-3-25 17:40 作者: 迷住 時(shí)間: 2025-3-25 21:49 作者: Connotation 時(shí)間: 2025-3-26 01:15
Serum and Urine Quantification of Delta-8 and Delta-9 Tetrahydrocannabinol Carboxylic Acid Using Gaergo glucuronidation. This method describes how to separate and quantify Δ9-THC-COOH and Δ8-THC-COOH in serum or urine using gas chromatography-mass spectrometry (GC-MS) and a deuterated internal standard.作者: 率直 時(shí)間: 2025-3-26 04:43
Book 2024Latest edition known pitfalls.?.Authoritative and up-to-date, .Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Second Edition. serves as a valuable resource for laboratory professionals who arealready utilizing mass spectrometry or considering bringing this technology to their labs..作者: Commemorate 時(shí)間: 2025-3-26 11:29
Book 2024Latest editionlity of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a sing作者: Femish 時(shí)間: 2025-3-26 15:34
1064-3745 expertsThis fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reag作者: ALLAY 時(shí)間: 2025-3-26 19:52 作者: 壓艙物 時(shí)間: 2025-3-26 23:04
Anlage des Forschungsprojektes,/MS method that can simultaneously analyze 49 commonly prescribed compounds in oral fluid. The assay is performed on an AB Sciex 4500 electrospray ionization mass spectrometer in multiple reaction monitoring mode.作者: legislate 時(shí)間: 2025-3-27 02:18 作者: CLIFF 時(shí)間: 2025-3-27 06:44 作者: 懸崖 時(shí)間: 2025-3-27 13:27 作者: 大酒杯 時(shí)間: 2025-3-27 17:38
https://doi.org/10.1007/978-1-4613-1605-3ent. The assay has a quantitative analytical range of 5?ng/mL–1000?ng/mL represented at seven levels for each of the four analytes. A unique stable isotopically labeled analogue is used as internal standard for each analyte. For high-throughput performance, the assay can be multiplexed between two LC channels.作者: paradigm 時(shí)間: 2025-3-27 18:32
https://doi.org/10.1007/978-3-322-94149-7tional isomers Δ8-THC-COOH and Δ9-THC-COOH as well as 7-carboxy cannabidiol (CBD-COOH) in urine that includes reverse-phase solid-phase extraction (SPE), followed by liquid chromatographic separation with a perfluorophenyl column, and detection by tandem mass spectrometry (LC-MS/MS).作者: 凈禮 時(shí)間: 2025-3-28 01:57
High-Throughput Quantitative LC-MS/MS Analysis of Benzodiazepines in Human Urine,into the LC-MS/MS instrument. Reversed-phase liquid chromatography is used to separate the mixture, and the TSQ Endura triple-quadrupole (QqQ) MS instrument performs detection via positive-mode electrospray ionization multiple reaction monitoring.作者: Free-Radical 時(shí)間: 2025-3-28 04:05 作者: 悶熱 時(shí)間: 2025-3-28 07:01
,11-Nor-9-Carboxy-Δ8-Tetrahydrocannabinol, 7-Carboxy Cannabidiol, and 11-Nor-9-Carboxy-Δ9-Tetrahydrotional isomers Δ8-THC-COOH and Δ9-THC-COOH as well as 7-carboxy cannabidiol (CBD-COOH) in urine that includes reverse-phase solid-phase extraction (SPE), followed by liquid chromatographic separation with a perfluorophenyl column, and detection by tandem mass spectrometry (LC-MS/MS).作者: 不足的東西 時(shí)間: 2025-3-28 12:22
Triazole Antifungal Quantification for Therapeutic Drug Monitoring in Serum by Liquid Chromatographe, centrifugation, and filtration. Analyte separation is achieved by reverse-phase chromatography using a dC18 column and a linear gradient of methanol in water. Analytes are detected by multiple reaction monitoring mass spectrometry and quantitated by comparison to a standard curve.作者: 托人看管 時(shí)間: 2025-3-28 15:58
Untargeted High-Resolution Mass Spectrometry for Detection of Natural Products and Confiscated Powdpropriate), in order to obtain and test the drugs, plants, herbals, or chemicals that were taken. Methods are needed for the extraction, purification, and untargeted mass spectral analysis of drugs from the donated or seized materials.作者: 勉強(qiáng) 時(shí)間: 2025-3-28 20:59 作者: affinity 時(shí)間: 2025-3-29 02:48 作者: 愚笨 時(shí)間: 2025-3-29 03:57
https://doi.org/10.1007/3-7908-1668-Xecialized clinical laboratories for decades. In clinical laboratories, it is used for compound identification and quantification. Due to the ability to provide specific identification, high sensitivity, and simultaneous analysis of multiple analytes (>100) in recent years, application of MS in routi作者: 倫理學(xué) 時(shí)間: 2025-3-29 09:58 作者: essential-fats 時(shí)間: 2025-3-29 12:53
https://doi.org/10.1007/3-7908-1668-Xpregabalin (PRG), rufinamide (RFM), and vigabatrin (VGB) have been approved and marketed since 1989. Accurate measurement of serum concentration of the antiepileptic drugs is crucial to achieve optimal efficacy and avoid adverse events. We describe an accurate and precise liquid chromatography-tande作者: 殖民地 時(shí)間: 2025-3-29 17:20
Developments in Cardiovascular Medicine(AED) can help control the incidence of epileptic seizures. AED therapeutic regimens often need to be individually tailored. Therapeutic drug monitoring (TDM) of AED is required to optimize therapeutic efficacy and minimize the risk of any associated destructive toxicities. We describe a turbulent f作者: 多骨 時(shí)間: 2025-3-29 20:37
Developments in Cardiovascular MedicineEDs can be used as single agents but are commonly administered in combination, as a multi-drug regimen. AEDs have narrow therapeutic windows. Therapeutic ranges may not be properly defined, and symptoms of toxic serum concentrations may include increased frequency of seizures, as seen when AED conce作者: OREX 時(shí)間: 2025-3-30 00:39 作者: 讓步 時(shí)間: 2025-3-30 06:06
Developments in Cardiovascular Medicineections in acute myeloid leukemia (AML) patients after receiving hematopoietic stem cell transplantation (HSCT). Recent studies have shown that atovaquone has shown potential as an anticancer agent. The high variability in atovaquone bioavailability prompts the need for therapeutic drug monitoring, 作者: 單調(diào)女 時(shí)間: 2025-3-30 08:13
https://doi.org/10.1007/978-1-4613-1605-3hy-tandem mass spectrometry (UPLC-MS/MS) using deuterated internal standards. This assay detects the presence of nine barbiturate drugs—amobarbital, barbital, butalbital, butabarbital, mephobarbital, secobarbital, pentobarbital, phenobarbital, and thiopental. This protocol describes two LC separatio作者: 史前 時(shí)間: 2025-3-30 16:06
https://doi.org/10.1007/978-1-4613-1605-3 a quantitative assay for phenobarbital, butalbital, pentobarbital/amobarbital, and secobarbital, as well as for confirmations following positive immunoassay drug screens in patient urine. Briefly, urine specimens are processed via dilute and shoot, i.e., by mixing the sample with 20 times volume of作者: Muscularis 時(shí)間: 2025-3-30 18:53 作者: beta-carotene 時(shí)間: 2025-3-30 22:42 作者: 接觸 時(shí)間: 2025-3-31 03:47
https://doi.org/10.1007/978-1-4613-1605-3in human urine. The assay is based on the direct and hydrolysis-free sample preparation protocol, i.e., dilute and shoot, whereby clarified urine specimens are diluted in internal standard reagent and injected into the LC-MS/MS instrument. The analytical platform employs reversed-phase liquid chroma作者: PRISE 時(shí)間: 2025-3-31 08:09 作者: Consensus 時(shí)間: 2025-3-31 10:54
Inszenierung und Kontingenz: Fallstudien,tudies have demonstrated that this combination of alkylating agents is very effective and well-tolerated prior to HCT. This combination is widely used for acute leukemia, advanced lymphoid malignancies, and multiple myeloma. Our goal was to develop an assay for the rapid measurement of both compound作者: 方便 時(shí)間: 2025-3-31 13:36 作者: incontinence 時(shí)間: 2025-3-31 18:02 作者: scotoma 時(shí)間: 2025-3-31 23:49
https://doi.org/10.1007/978-3-322-94149-7malignancies and bone marrow failure syndromes. While allo-HCT can be highly effective, it is met with significant bone marrow conditioning regimen-related toxicities and complications such as infections related to poor immune reconstitution. This chapter describes the measurement of clofarabine and作者: AGONY 時(shí)間: 2025-4-1 05:09 作者: CYN 時(shí)間: 2025-4-1 08:05
Anlage des Forschungsprojektes,y for direct observation of a sample collection and, thus, a lower risk of adulteration. To address this trend, we have developed a quantitative LC-MS/MS method that can simultaneously analyze 49 commonly prescribed compounds in oral fluid. The assay is performed on an AB Sciex 4500 electrospray ion作者: intricacy 時(shí)間: 2025-4-1 14:04
Uttam GargIncludes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts
