標(biāo)題: Titlebook: Clinical Applications of Mass Spectrometry in Biomolecular Analysis; Methods and Protocol Uttam Garg Book 2022Latest edition The Editor(s) [打印本頁] 作者: fathom 時間: 2025-3-21 16:30
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書目名稱Clinical Applications of Mass Spectrometry in Biomolecular Analysis被引頻次
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書目名稱Clinical Applications of Mass Spectrometry in Biomolecular Analysis讀者反饋
書目名稱Clinical Applications of Mass Spectrometry in Biomolecular Analysis讀者反饋學(xué)科排名
作者: 壓倒性勝利 時間: 2025-3-22 00:02 作者: Ligneous 時間: 2025-3-22 04:28
Uttam GargIncludes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts作者: myelography 時間: 2025-3-22 08:36
Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/227756.jpg作者: Jubilation 時間: 2025-3-22 12:23 作者: 原告 時間: 2025-3-22 16:58 作者: 原告 時間: 2025-3-22 18:21 作者: 徹底明白 時間: 2025-3-22 21:44
Nicholas H. Bingham ScD,Rüdiger Kiesel PhDses. Specific acylcarnitines accumulate as a result of various organic acidurias and fatty acid oxidation disorders, and, thus, acylcarnitines profiles are used for the diagnosis of these disorders. Acylcarnitines monitoring can also be used for the follow-up of patients with these disorders. Tandem作者: 前兆 時間: 2025-3-23 02:24
Nicholas H. Bingham ScD,Rüdiger Kiesel PhDa as a clinical diagnostic test. Determination of SAM/SAH in plasma (20?μL) was performed by high-performance liquid chromatography coupled with electrospray positive ionization tandem mass spectrometry (HPLC-ESI-MS/MS). Calibrators (SAM and SAH) and internal standards (.H.-SAM and .H.-SAH) were inc作者: MAUVE 時間: 2025-3-23 07:05
Stochastic Processes in Continuous Time,. Its measurement is also used in the investigation of adrenal incidentaloma, adrenal carcinoma, Addison’s disease, congenital adrenal hyperplasia, renal artery stenosis, and renal tubular channelopathies. We describe a simple and robust method for the accurate and precise measurement of aldosterone作者: Popcorn 時間: 2025-3-23 10:22
Nicholas H. Bingham ScD,Rüdiger Kieselomponent in the detection of inborn errors of metabolism for six decades. Detection of amino acids using mass spectrometry offers advantages in speed and analytic specificity. Employing methanol extraction and controlled butylation, C8 reversed-phase chromatography, and MS/MS detection, 32 amino aci作者: vasculitis 時間: 2025-3-23 16:19 作者: 擴(kuò)音器 時間: 2025-3-23 18:31 作者: Melatonin 時間: 2025-3-24 01:35 作者: neolith 時間: 2025-3-24 02:39
Multifactors Model and Portfolio Management cortisol is of immense clinical benefit. In particular, salivary cortisol levels have been shown to correlate well with diurnal changes in cortisol levels in serum and have been used widely for monitoring of cortisol levels for diagnosis and prognosis purposes. We present a sensitive, fast, and rob作者: 協(xié)迫 時間: 2025-3-24 08:24
Time Series of Return and Volatilityrenal or pituitary tumor. While serum cortisol levels fluctuate in response to time of day, stress, and concentrations of cortisol-binding globulin (CBG), a 24-h urine collection measures the cortisol produced over the entire day and does not suffer from as much variability as a serum measurement..W作者: 使害怕 時間: 2025-3-24 13:11 作者: 酷熱 時間: 2025-3-24 17:19 作者: Ascribe 時間: 2025-3-24 19:05 作者: Opponent 時間: 2025-3-25 02:01
Risk-sharing in the Pharmaceutical Industryitter in human cerebrospinal fluid (CSF) as a clinical diagnostic test. Determination of CSF GABA has clinical utility in diagnosing inborn errors of GABA metabolism, specifically for deficiencies of GABA-transaminase and succinic semialdehyde dehydrogenase. Quantitation of CSF GABA is performed uti作者: 別炫耀 時間: 2025-3-25 03:46 作者: reject 時間: 2025-3-25 07:40
Contributions to Management Sciencemovanillic acid (HVA) and vanillylmandelic acid (VMA) are important catecholamine metabolites that can be measured to provide relatively rapid laboratory diagnosis and clinical follow-up of neuroblastoma. We present a procedure to quantify HVA and VMA in urine samples which have been diluted to a cr作者: Instinctive 時間: 2025-3-25 15:11
Risk-sharing in the Pharmaceutical Industryleacetic acid (5-HIAA) is the primary urinary metabolite of serotonin, making measurement of 5-HIAA useful in the diagnosis and management of carcinoid tumors. Here we describe a simple, inexpensive, and fast method for the detection and quantification of 5-HIAA in urine. Samples are prepared by sim作者: Obstruction 時間: 2025-3-25 19:10 作者: frozen-shoulder 時間: 2025-3-25 22:21
1064-3745 expertsThis updated volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and作者: seroma 時間: 2025-3-26 00:44 作者: Expand 時間: 2025-3-26 07:30
A Simple, Fast, and Reliable LC-MS/MS Method for the Measurement of Homovanillic Acid and Vanillylmon a reverse-phase liquid chromatography column followed by detection using electrospray ionization triple quadrupole mass spectrometry (ESI-MS/MS), wherein qualifier and quantifier ion transitions are monitored. This is a simple and fast analytical method with an injection-to-injection time of 4?min.作者: Lasting 時間: 2025-3-26 10:26 作者: 無政府主義者 時間: 2025-3-26 12:50 作者: 性上癮 時間: 2025-3-26 19:36
System Performance Monitoring in Clinical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)s, largely following CLSI-C62A guidance. Though routine checks ensure the quality of results reported for each run, there is also a need to evaluate metrics between runs over time. Post-implementation performance monitoring of LC-MS/MS methods is typically focused on calibration curves, retention times, peak intensities, and ion ratios.作者: Insulin 時間: 2025-3-26 23:23 作者: Fresco 時間: 2025-3-27 03:16
https://doi.org/10.1007/978-3-642-38598-8nalysis of many analytes. Other advantages of mass spectrometry include simultaneous analysis of multiple analytes (>100) and generally limited requirement for specialized reagents. Commonly measured analytes by mass spectrometry include metabolites, drugs, hormones, and proteins.作者: Slit-Lamp 時間: 2025-3-27 06:44
Jos Brils,Werner Brack,Jan E. Vermaats, largely following CLSI-C62A guidance. Though routine checks ensure the quality of results reported for each run, there is also a need to evaluate metrics between runs over time. Post-implementation performance monitoring of LC-MS/MS methods is typically focused on calibration curves, retention times, peak intensities, and ion ratios.作者: 大洪水 時間: 2025-3-27 12:04
Risk-sharing in the Pharmaceutical Industryple 1:1 dilution. The instrumental analysis is performed by chromatographic separation on a reverse-phase analytical column followed by detection using a triple quadrupole mass spectrometer with electrospray ionization in positive ion mode. Data are acquired by multiple reaction monitoring (MRM).作者: Exonerate 時間: 2025-3-27 15:05 作者: AGOG 時間: 2025-3-27 19:36
Nicholas H. Bingham ScD,Rüdiger Kiesel, and limits of detection are at least 1.0?μM. Important isobaric amino acids are distinguished by chromatography or by unique patterns of fragmentation following collision-induced dissociation (CID). The technique employs commercially available reagents and may be expanded and customized for specific clinical or research settings.作者: PON 時間: 2025-3-27 23:54
Time Series of Return and VolatilityUrine samples, combined with stable isotope-labeled internal standards, are extracted by liquid-liquid extraction using ethyl acetate and hexane. An API 5500 mass spectrometer operated in positive atmospheric pressure chemical ionization (APCI) mode is used for detection.作者: 帶子 時間: 2025-3-28 05:27
Risk Diversification and Market Index Modelr the simultaneous determination of these analytes using a normal-phase HILIC column after analyte derivatization. The approach is suitable for neonatal screening follow-ups and monitoring of the treatment for creatine deficiency syndromes.作者: 同義聯(lián)想法 時間: 2025-3-28 07:07
Contributions to Management Scienceod cells. Fatty acids are hydrolyzed and extracted from the biological matrix, followed by derivatization with pentafluorobenzyl bromide and subsequent analysis by gas chromatography-negative chemical ionization-mass spectrometry (GC-NCI-MS).作者: 欄桿 時間: 2025-3-28 14:00 作者: Oration 時間: 2025-3-28 17:07 作者: 橫條 時間: 2025-3-28 20:03
Comprehensive Determination of Amino Acids for Diagnosis of Inborn Errors of Metabolism,, and limits of detection are at least 1.0?μM. Important isobaric amino acids are distinguished by chromatography or by unique patterns of fragmentation following collision-induced dissociation (CID). The technique employs commercially available reagents and may be expanded and customized for specific clinical or research settings.作者: spondylosis 時間: 2025-3-29 01:14
Measurement of Urinary Free Cortisol and Cortisone by LC-MS/MS,Urine samples, combined with stable isotope-labeled internal standards, are extracted by liquid-liquid extraction using ethyl acetate and hexane. An API 5500 mass spectrometer operated in positive atmospheric pressure chemical ionization (APCI) mode is used for detection.作者: Optic-Disk 時間: 2025-3-29 06:14 作者: CON 時間: 2025-3-29 10:57 作者: Genistein 時間: 2025-3-29 15:25
Quantitation of Neuroblastoma Markers Homovanillic Acid (HVA) and Vanillylmandelic Acid (VMA) in Urbis(trimethylsilyl)trifluoroacetamide (BSTFA) with 1% trimethylchlorosilane (TMCS) and pyridine mixture is added to the dried extract to create trimethylsilyl derivatives of HVA and VMA. The derivatized compounds are measured using gas chromatography–mass spectrometry (GC/MS).作者: 越自我 時間: 2025-3-29 15:34 作者: 有組織 時間: 2025-3-29 21:40
https://doi.org/10.1007/978-3-319-14157-2y the ones encountered most often. The method presented here is performed on urine and utilizes butanolic HCL to derivatize acylcarnitines, ultra-performance liquid chromatography to resolve C4- and C5-DC isomers and isobars, and quantitation of these species using multiple-reaction monitoring (MRM).作者: choleretic 時間: 2025-3-30 03:10 作者: HAWK 時間: 2025-3-30 06:04
Multifactors Model and Portfolio Managementssay has a total run time of 5.8?minutes and a limit of quantification of 0.5?ng/mL with a linear range up to 100?ng/mL. No carryover was observed at 10?μg/mL. This assay also incorporates the routine monitoring of prednisolone, a potential interferent to salivary cortisol.作者: 過濾 時間: 2025-3-30 09:28
Risk Diversification and Market Index Modelsamples are reconstituted in a water:methanol solution and separated chromatographically using a reversed-phase HPLC column. Subsequent mass spectrometry is performed using both positive ion mode for Te and negative ion mode for E2.作者: 都相信我的話 時間: 2025-3-30 13:48 作者: 柔美流暢 時間: 2025-3-30 17:57 作者: Harness 時間: 2025-3-30 22:25 作者: 租約 時間: 2025-3-31 02:18 作者: Mendicant 時間: 2025-3-31 07:17 作者: 骨 時間: 2025-3-31 10:44
Book 2022Latest editionooting and avoiding known pitfalls.?.Cutting-edge and practical,?.Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols, Second Edition.?is an ideal resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories..作者: Indurate 時間: 2025-3-31 14:05
Introduction to Mass Spectrometry for Bimolecular Analysis in a Clinical Laboratory,en used in research and specialized clinical laboratories for decades, only in recent years has mass spectrometry become popular in routine clinical laboratories. Mass spectrometry, especially when coupled with gas chromatography or liquid chromatography, provides very specific and often sensitive a作者: 占卜者 時間: 2025-3-31 17:50 作者: resilience 時間: 2025-4-1 01:14 作者: predict 時間: 2025-4-1 03:42 作者: 含沙射影 時間: 2025-4-1 08:38 作者: 膽小懦夫 時間: 2025-4-1 12:43
Comprehensive Determination of Amino Acids for Diagnosis of Inborn Errors of Metabolism,omponent in the detection of inborn errors of metabolism for six decades. Detection of amino acids using mass spectrometry offers advantages in speed and analytic specificity. Employing methanol extraction and controlled butylation, C8 reversed-phase chromatography, and MS/MS detection, 32 amino aci作者: FUME 時間: 2025-4-1 16:26
Quantification of Branched-Chain Amino Acids in Plasma by High-Performance Liquid Chromatography-Ta in the body. Deficiency in branched-chain ketoacid dehydrogenase complex, an enzyme required for metabolism of those amino acids, will lead to elevation and accumulation of BCAA and ketoacids in bodily fluids. This results in maple syrup urine disease (MSUD), a condition estimated to affect 1 in 10作者: Airtight 時間: 2025-4-1 21:44
Quantitation of Butyrylcarnitine, Isobutyrylcarnitine, and Glutarylcarnitine in Urine Using Ultra-Pation disorders, specific acylcarnitine species accumulate in a pattern that is characteristic for each disease. For this reason, acylcarnitine analysis is widely used for screening and diagnosis of inherited disorders of metabolism. The most common method for acylcarnitine analysis uses flow inject
