標(biāo)題: Titlebook: Circadian Rhythms and Their Impact on Aging; S. Michal Jazwinski,Victoria P Belancio,Steven M H Book 2017 The Editor(s) (if applicable) an [打印本頁] 作者: 爆發(fā) 時(shí)間: 2025-3-21 19:49
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書目名稱Circadian Rhythms and Their Impact on Aging讀者反饋學(xué)科排名
作者: Kindle 時(shí)間: 2025-3-21 20:50
Siedlungsstrukturen und Stadtsysteme,gression of age-related lung diseases, and the underlying molecular mechanisms, are still largely unknown. The chronobiology of the lung and the role of the circadian clock in the pathophysiology of age-related lung disease will be discussed in this chapter. We describe the molecular links between t作者: Magnificent 時(shí)間: 2025-3-22 00:50
Phasenmodelle der Stadtentwicklung,sleep, and eating at irregular hours. This is causing more stress and less time to spend outdoors. All of these factors are contributing to circadian disruption “in general” but more importantly?to circadian disruption of bone rhythms. Bone metabolism displays circadian variation that is coincident 作者: champaign 時(shí)間: 2025-3-22 05:04
Gunther Maier,Franz T?dtling,Michaela Trippltrointestinal aging is reviewed. Although we know quite a lot about the physiological and molecular mechanisms of circadian clocks in mammals, we know very little about the mechanisms of food-entrainable rhythmicity. The role played by the pineal hormone melatonin has been posited as a key to unders作者: expire 時(shí)間: 2025-3-22 11:56
Gunther Maier,Franz T?dtling,Michaela Tripplgical or cellular level. However, in mammals internal clock becomes less rhythmic and more vulnerable to external disturbing stimuli with age. In this chapter we briefly describe rodent circadian system physiology, rhythms and clock genes disturbance in aging and age-related diseases, models of gene作者: LEVER 時(shí)間: 2025-3-22 13:44
Gunther Maier,Franz T?dtling,Michaela Trippl-autonomous and consists of molecular negative feedback loops that turn over with an endogenous circa 24?h period. While daily oscillations in the activity of clock genes and proteins are well understood in young fruit flies ., much less is known about how the clock mechanism changes during organism作者: LEVER 時(shí)間: 2025-3-22 20:18 作者: 不可接觸 時(shí)間: 2025-3-23 00:08
https://doi.org/10.1007/3-211-31908-5 decreased proteostasis. Indeed, the two main intracellular protein degradation systems, autophagy and proteasome, have been shown to generally decline with age while age-related alterations of redox homeostasis has also been reported. Both antioxidant defenses and autophagy have been shown to be re作者: 宣稱 時(shí)間: 2025-3-23 01:52 作者: 珠寶 時(shí)間: 2025-3-23 09:18 作者: gene-therapy 時(shí)間: 2025-3-23 10:38 作者: FIR 時(shí)間: 2025-3-23 14:36 作者: 放氣 時(shí)間: 2025-3-23 18:19 作者: PAEAN 時(shí)間: 2025-3-23 22:45 作者: Soliloquy 時(shí)間: 2025-3-24 05:28
Circadian Rhythms and Their Impact on Aging978-3-319-64543-8Series ISSN 2199-9007 Series E-ISSN 2199-9015 作者: CUR 時(shí)間: 2025-3-24 07:30
S. Michal Jazwinski,Victoria P Belancio,Steven M HDeals in a multi-faceted way with an emerging area in longevity and healthy aging research.A book on this topic is not currently on the market.Summarizes the current state of the art and outlines futu作者: Landlocked 時(shí)間: 2025-3-24 14:21 作者: 兵團(tuán) 時(shí)間: 2025-3-24 18:30 作者: 震驚 時(shí)間: 2025-3-24 20:19
978-3-319-87816-4The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl作者: 啤酒 時(shí)間: 2025-3-25 00:00 作者: gnarled 時(shí)間: 2025-3-25 03:34 作者: 一小塊 時(shí)間: 2025-3-25 09:38
Developing Circadian Therapeutics Against Age-Related Metabolic Decline,o identify novel small-molecule therapeutics that enhance circadian and metabolic functions. Given that a weakened clock is in part responsible for the metabolic deterioration during aging, such circadian-based therapeutics could be exploited to decelerate metabolic decline and ultimately promote healthy aging.作者: Intractable 時(shí)間: 2025-3-25 14:43
Circadian Sleep-Wake Activity Patterns During Aging, for these associations. In addition, future studies will be needed to test whether interventions (e.g. physical activity, bright light exposure, cataract surgery) that regulate circadian activity rhythms will improve health outcomes in the elderly.作者: 未完成 時(shí)間: 2025-3-25 18:08 作者: Curmudgeon 時(shí)間: 2025-3-25 23:07
Gunther Maier,Franz T?dtling,Michaela Trippltanding aging and clock function, but the evidence is incomplete. Finally, new data about aging and circadian control of the intestinal microbiome is placed in the context of the circadian system as a whole.作者: plasma 時(shí)間: 2025-3-26 02:11 作者: 令人悲傷 時(shí)間: 2025-3-26 06:45
Siedlungsstrukturen und Stadtsysteme,re, the impact of external factors in the intrinsic circadian regulation will be integrated into the complex profiling of age-related lung diseases as well as chrono-therapeutic approaches. Finally, gaps in our knowledge and future directions will be discussed.作者: SLING 時(shí)間: 2025-3-26 10:38
Gunther Maier,Franz T?dtling,Michaela Tripplpresent evidence that these five metabolic linkages affecting aging provide feedback to the clock. Metabolism is not only driven by the clock, but metabolism is likely to provide feedback to the clock by a variety of metabolic mechanisms.作者: 滔滔不絕地講 時(shí)間: 2025-3-26 16:02
Pulmonary Diseases, a Matter of Time,re, the impact of external factors in the intrinsic circadian regulation will be integrated into the complex profiling of age-related lung diseases as well as chrono-therapeutic approaches. Finally, gaps in our knowledge and future directions will be discussed.作者: 酷熱 時(shí)間: 2025-3-26 17:17 作者: 植物群 時(shí)間: 2025-3-27 00:12 作者: Chipmunk 時(shí)間: 2025-3-27 02:55
Circadian System and Aging in Rodent Models,tic (clock genes mutant/knockout mice) and environmental (light-dark regimens manipulation) circadian disturbance. In the end some interventions which may be used to improve circadian output are considered.作者: Myocarditis 時(shí)間: 2025-3-27 08:21
Book 2017ism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book 作者: Talkative 時(shí)間: 2025-3-27 12:17 作者: 磨坊 時(shí)間: 2025-3-27 17:16 作者: 擦試不掉 時(shí)間: 2025-3-27 18:59 作者: 充滿裝飾 時(shí)間: 2025-3-27 23:32 作者: 劇毒 時(shí)間: 2025-3-28 03:38
https://doi.org/10.1007/3-211-31908-5for orderly organizations of muscle mitochondria. Interestingly, . whole body knockout mice develop premature aging phenotypes, while AHA-1 over-expression increases lifespan in worms. Given that mitochondrial dysfunction appears to be a common feature associated with aging, obesity, and related met作者: 事情 時(shí)間: 2025-3-28 07:03 作者: 新奇 時(shí)間: 2025-3-28 12:58
Gunther Maier,Franz T?dtling,Michaela Tripplch as cancer and diabetes and contributes to development of these pathologies. Both systems, the circadian clock and mTOR pathway, have been implicated in the control of aging in different organisms. Recently several groups reported on the existence of the crosstalk between the circadian clock and m作者: Ointment 時(shí)間: 2025-3-28 18:17 作者: MORPH 時(shí)間: 2025-3-28 20:48
Gunther Maier,Franz T?dtling,Michaela Tripplmicity in the elderly. After training, a reduction in the fragmentation of the rest-activity rhythm, an increase in amplitude of activity-rest and core temperature rhythms, and enhancement of sleep and diurnal vigilance have been reported. We may suppose that the exercise-mediated increase in core t作者: 金盤是高原 時(shí)間: 2025-3-29 01:41
Circadian Dysregulation and Melatonin Rhythm Suppression in the Context of Aging,least provisionally linked to circadian disruption and/or melatonin suppression. While the findings are not definitive, there is certainly credible data to warrant the conclusion that regular circadian rhythms at multiple levels, including a stable day:night melatonin cycle, enhance life quality and作者: 彎彎曲曲 時(shí)間: 2025-3-29 05:52
Circadian Regulation of Bone,e are many reviews on this subject matter described throughout the chapter. Rather, the focus of this chapter is to describe clock gene expression and function in bone and how their rhythms impact on osteoblast and osteoclast activity and differentiation and on bone metabolism; and then discuss vari作者: Merited 時(shí)間: 2025-3-29 08:49 作者: modish 時(shí)間: 2025-3-29 13:02
Circadian Control of Mitochondrial Dynamics and Its Implication in Aging,for orderly organizations of muscle mitochondria. Interestingly, . whole body knockout mice develop premature aging phenotypes, while AHA-1 over-expression increases lifespan in worms. Given that mitochondrial dysfunction appears to be a common feature associated with aging, obesity, and related met作者: Presbyopia 時(shí)間: 2025-3-29 17:37 作者: 范例 時(shí)間: 2025-3-29 23:29 作者: 分解 時(shí)間: 2025-3-30 03:24 作者: 美色花錢 時(shí)間: 2025-3-30 07:12 作者: 敲詐 時(shí)間: 2025-3-30 11:36
2199-9007 uman. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.978-3-319-87816-4978-3-319-64543-8Series ISSN 2199-9007 Series E-ISSN 2199-9015 作者: Expressly 時(shí)間: 2025-3-30 13:47
