標(biāo)題: Titlebook: Circadian Regulation; Methods and Protocol Guiomar Solanas,Patrick -Simon Welz Book 2022 The Editor(s) (if applicable) and The Author(s), u [打印本頁] 作者: Herbaceous 時間: 2025-3-21 19:43
書目名稱Circadian Regulation影響因子(影響力)
書目名稱Circadian Regulation影響因子(影響力)學(xué)科排名
書目名稱Circadian Regulation網(wǎng)絡(luò)公開度
書目名稱Circadian Regulation網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Circadian Regulation被引頻次
書目名稱Circadian Regulation被引頻次學(xué)科排名
書目名稱Circadian Regulation年度引用
書目名稱Circadian Regulation年度引用學(xué)科排名
書目名稱Circadian Regulation讀者反饋
書目名稱Circadian Regulation讀者反饋學(xué)科排名
作者: FELON 時間: 2025-3-21 22:30
Regional Stratigraphy of North Americadence indicated disturbance of the circadian clock leads to an increased susceptibility to?several diseases. Therefore, a great effort has been made?to find small molecules that regulate circadian rhythm by high-throughput methods.?Having crystal structures of core clock proteins, makes?them?amenabl作者: follicle 時間: 2025-3-22 02:35 作者: INERT 時間: 2025-3-22 07:53
Rita Vilk?,Lina Pareigien?,Aldona Stalgien?us omic technologies. We briefly present two resources for the study of circadian omic (e.g. transcriptomic, metabolomic, proteomic) time series. First, BIO_CYCLE is a deep-learning-based program and web server that can analyze omic time series and statistically assess their periodic nature and, whe作者: 誘使 時間: 2025-3-22 12:08 作者: Jingoism 時間: 2025-3-22 13:42
https://doi.org/10.1007/978-3-319-54112-9ian rhythms exacerbates a range of human ailments including cardiovascular, metabolic, and gastrointestinal diseases. Determining the state of a patient’s circadian rhythms and clock-controlled signaling pathways has important implications for precision and personalized medicine, from improving the 作者: Jingoism 時間: 2025-3-22 20:14 作者: NOCT 時間: 2025-3-22 21:22 作者: 遺傳 時間: 2025-3-23 01:47
Irene Ring,Bernd Klauer,Bengt ?. M?nssonrcellular coupling among cell-autonomous circadian oscillators is crucial for understanding how cellular ensembles generate and sustain coherent circadian rhythms on the tissue level, and thus, rhythmic organ functions. Here we describe a protocol for studying intercellular coupling among peripheral作者: disparage 時間: 2025-3-23 06:33
Terence J. Centner,Lewell F. Gunter can be cultured for several days, the circadian clock can be synchronized, and these primary cells can be utilized for functional gene regulation analysis and metabolic studies. In this chapter, we describe detailed methodology for isolation of viable primary hepatocytes, techniques for culturing t作者: Decline 時間: 2025-3-23 12:17
Terence J. Centner,Lewell F. Gunterrinsic ~24-h rhythm can be measured in the neuronal firing rate both in vivo and in vitro, where it continues unperturbed. This robust reporter of endogenous physiology in the SCN brain slice can be widely used to study dynamic changes in SCN physiology, its changing sensitivity to phase-altering si作者: 無底 時間: 2025-3-23 17:08
Terence J. Centner,Lewell F. Gunter to periodic environmental signals (zeitgebers), and regulates subordinate oscillators elsewhere in the brain and in the periphery, a variety of molecular methods have been applied. Multiple label immunocytochemistry and in situ hybridization provide anatomical insights that complement physiological作者: 惡意 時間: 2025-3-23 18:33 作者: GLUT 時間: 2025-3-23 23:43
Michael Fritsch,Michael Wyrwichte how and with what kinetics peripheral clocks integrate circadian signals from the suprachiasmatic nucleus, which harbors the circadian master pacemaker, with other systemic and environmental cues, such as those associated with feeding and hormones. Organ sampling around the clock, followed by the作者: 疼死我了 時間: 2025-3-24 04:08 作者: 不給啤 時間: 2025-3-24 08:16
https://doi.org/10.1007/978-1-349-16849-1ally applied electric field. Here we describe the application of DEP to the measurement of circadian rhythms in a non-nucleated cell type, the human red blood cell. Using DEP, population-level electrophysiology of ~20,000 red blood cells can be measured from start to finish in less than 3?min, and c作者: 善變 時間: 2025-3-24 10:54
J. L. Roy,E. Tanczyk,P. Lapointemune defense under inflammatory conditions. In all cases, accurate measurements of the absolute number of infiltrated cells and of their localization are important to understand steady-state or inflammatory migration patterns and kinetics. Here we present a method to obtain accurate information on b作者: 短程旅游 時間: 2025-3-24 18:45
Paul E. Schenk,R. T. Haworth,G. KellingNETs are circadian in nature as mouse and human neutrophils preferentially deploy them at night or early morning. Traditionally, NETs have been quantified using a plethora of methods including immunofluorescence and ELISA-based assays; however few options are available to visualize them in vivo. Her作者: 變化 時間: 2025-3-24 20:03
Guiomar Solanas,Patrick -Simon WelzIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts作者: predict 時間: 2025-3-25 02:32
Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/226572.jpg作者: Coronation 時間: 2025-3-25 05:54
Circadian Regulation978-1-0716-2249-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: abject 時間: 2025-3-25 08:56 作者: 斥責(zé) 時間: 2025-3-25 13:19 作者: creatine-kinase 時間: 2025-3-25 16:14 作者: alcohol-abuse 時間: 2025-3-25 21:53
Isolation and Sorting of Epidermal Interfollicular Stem Cells for the Study of Circadian Rhythms,onmental challenges. For this reason, examining the circadian transcriptome of interfollicular stem cells has become a central technique for functional skin studies. In this chapter, we describe a widely adopted protocol for the isolation and analysis of circadian rhythms in adult stem cells of the epidermis.作者: 安慰 時間: 2025-3-26 02:22 作者: 話 時間: 2025-3-26 08:06 作者: 解凍 時間: 2025-3-26 11:45 作者: upstart 時間: 2025-3-26 13:35 作者: constellation 時間: 2025-3-26 20:20 作者: conjunctiva 時間: 2025-3-27 00:35
Regional Stratigraphy of North Americae to?structure-based drug design studies. Here, we describe virtual screening methods that can be utilized for the identification of small molecules regulating the activity of core clock protein Cryptochrome 1.作者: 背叛者 時間: 2025-3-27 02:31
Terence J. Centner,Lewell F. Gunterhigh-throughput capability and spatial resolution. It can be readily adapted to a wide variety of applications, such as different sample types and plate sizes, under a wide range of physiologically relevant conditions.作者: Fsh238 時間: 2025-3-27 07:31 作者: Coeval 時間: 2025-3-27 11:06 作者: FADE 時間: 2025-3-27 14:18 作者: HAIL 時間: 2025-3-27 21:09 作者: JAMB 時間: 2025-3-27 23:15
Olfa Manai Daboussi,Amel Hedhliircadian clock mechanism, and can be great therapeutic candidates. Here we describe the detailed methods of measuring cellular circadian rhythms in a high-throughput manner for chemical screening to identify compounds that affect circadian rhythms by targeting clock-related proteins.作者: shrill 時間: 2025-3-28 03:11
Terence J. Centner,Lewell F. Gunterlysis and metabolic studies. In this chapter, we describe detailed methodology for isolation of viable primary hepatocytes, techniques for culturing these cells, methods for synchronization of the circadian clock, transfection and luciferase reporter analysis, as well as glucose production assays as a functional readout of metabolic state.作者: Affiliation 時間: 2025-3-28 07:57 作者: 增減字母法 時間: 2025-3-28 13:16 作者: Inordinate 時間: 2025-3-28 17:42 作者: limber 時間: 2025-3-28 22:43 作者: 溫室 時間: 2025-3-28 23:24
Irene Ring,Bernd Klauer,Bengt ?. M?nssoning of several consecutive steps in which organotypic tissue cultures or cells can be used. Our approach targets the potential resetting mechanism at three levels: the hormone, the direct clock gene target, and the tissue clock response.作者: Cubicle 時間: 2025-3-29 03:28
Irene Ring,Bernd Klauer,Bengt ?. M?nssonpheroids to simulate in vivo tissue integrity, as well as to increase complexity of cell–cell interactions and the abundance of potential coupling factors. Circadian rhythms are monitored using live-cell imaging of spheroids equipped with circadian reporters over several days.作者: 廢除 時間: 2025-3-29 08:38 作者: 改良 時間: 2025-3-29 12:50 作者: 小卷發(fā) 時間: 2025-3-29 17:42 作者: osteocytes 時間: 2025-3-29 21:48
In Vivo Imaging of Circadian NET Formation During Lung Injury by Four-Dimensional Intravital Microsmodel of acute lung injury. The method allows four-dimensional capture and quantification of NET formation dynamics over time and should be a useful resource for those interested in visualizing neutrophil responses in vivo.作者: homeostasis 時間: 2025-3-30 02:35
Book 2022d cutting-edge,?.Circadian Regulation: Methods and Protocols .aims to be a?useful practical guide to researches to help further their study in this field.?.Chapters 3, 4, 8, and 17? are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com..作者: 單挑 時間: 2025-3-30 07:14 作者: Antimicrobial 時間: 2025-3-30 08:23 作者: Arable 時間: 2025-3-30 16:21
Michael Fritsch,Michael Wyrwichiferase reporters has emerged as a powerful method to acquire continuous, high-resolution datasets from freely moving individual mice. Here, we share our experience and protocols with this technique, using the RT-Biolumicorder setup.作者: anarchist 時間: 2025-3-30 18:46
Sleep Under Preindustrial Conditions: What We Can Learn from It,access to artificial light has delayed the daily onset of sleep but has had a smaller effect on its offset, leading to an overall reduction in sleep duration that is pervasive in modern societies. In this chapter we discuss these studies, highlight their main findings, and point to their limitations.作者: Cumulus 時間: 2025-3-31 00:22 作者: Finasteride 時間: 2025-3-31 01:11 作者: Manifest 時間: 2025-3-31 06:17 作者: 法官 時間: 2025-3-31 12:10
1064-3745 urther their study in this field.?.Chapters 3, 4, 8, and 17? are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com..978-1-0716-2251-3978-1-0716-2249-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Delectable 時間: 2025-3-31 13:24
Analysis of Complex Circadian Time Series Data Using Wavelets,te and interpret high-resolution time-dependent spectral results, analyze the main oscillatory component, and to subsequently determine these main components’ time-dependent instantaneous period, amplitude, and phase. We introduce step-by-step how such an analysis can be done by means of the easy-to作者: 喊叫 時間: 2025-3-31 18:54 作者: NAUT 時間: 2025-3-31 23:58
Anatomical Methods to Study the Suprachiasmatic Nucleus,s of the subjects. Nevertheless, it is possible to resolve intracellular colocalization and regional expression of functionally important transcripts and/or their peptide products that serve as neuromodulators or neurotransmitters. Armed with these tools and others, understanding of the mechanisms b作者: Noctambulant 時間: 2025-4-1 03:44 作者: 漂浮 時間: 2025-4-1 05:59
https://doi.org/10.1007/978-3-319-54112-9including immunofluorescence, live cell confocal microscopy, and bioluminescence. These methods can be applied to evaluate the state of circadian rhythms and circadian clock-gated cell division cycles using mouse and human intestinal enteroids.作者: 桉樹 時間: 2025-4-1 11:13
Terence J. Centner,Lewell F. Gunters of the subjects. Nevertheless, it is possible to resolve intracellular colocalization and regional expression of functionally important transcripts and/or their peptide products that serve as neuromodulators or neurotransmitters. Armed with these tools and others, understanding of the mechanisms b作者: 嬰兒 時間: 2025-4-1 17:20
Sleep Under Preindustrial Conditions: What We Can Learn from It,nd light per se can acutely inhibit sleep. Throughout evolution, these sleep regulatory systems became highly sensitive to the effects of light and they can be affected by the relatively low light intensities that are used indoors. Thus, postindustrial living conditions have created built environmen作者: 審問 時間: 2025-4-1 20:55
