標(biāo)題: Titlebook: Chromothripsis; Methods and Protocol Franck Pellestor Book 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018 Massive [打印本頁] 作者: deteriorate 時間: 2025-3-21 16:31
書目名稱Chromothripsis影響因子(影響力)
書目名稱Chromothripsis影響因子(影響力)學(xué)科排名
書目名稱Chromothripsis網(wǎng)絡(luò)公開度
書目名稱Chromothripsis網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Chromothripsis被引頻次
書目名稱Chromothripsis被引頻次學(xué)科排名
書目名稱Chromothripsis年度引用
書目名稱Chromothripsis年度引用學(xué)科排名
書目名稱Chromothripsis讀者反饋
書目名稱Chromothripsis讀者反饋學(xué)科排名
作者: 自負的人 時間: 2025-3-21 21:03 作者: 向下 時間: 2025-3-22 03:17 作者: 逃避責(zé)任 時間: 2025-3-22 06:05 作者: 藝術(shù) 時間: 2025-3-22 11:06
Analysis of Chromothripsis by Combined FISH and Microarray Analysisermine the organization of abnormal genomes after chromothripsis and other types of complex genome rearrangement. DNA microarrays can identify the changes in copy number, but they do not give information on the organization of the abnormal chromosomes, balanced rearrangements, or abnormalities of th作者: 表示問 時間: 2025-3-22 14:11 作者: 表示問 時間: 2025-3-22 20:43
Identification of Chromothripsis in Biopsy Using SNP-Based Microarrays have shown that chromothripsis or chromoanasynthesis can result in complex genomic rearrangements by a single catastrophic event rather than several incremental steps. These two novel phenomena suggest an evolutionary modality for cancer cells to circumvent individual mutational events with one si作者: 金桌活畫面 時間: 2025-3-23 00:35
Detection of Chromothripsis in Plantsly complex structural rearrangements. In plants, chromothripsis has been observed as a result of mitotic malfunction connected with the incomplete loss of haploid inducer chromosomes during uniparental genome elimination. Uniparental genome elimination, a process that results in haploid induction, i作者: 興奮過度 時間: 2025-3-23 04:24 作者: Feature 時間: 2025-3-23 09:16
Experimental Determination of Checkpoint Adaptation by?Mitotic Shake-Off and Microscopy this process frequently contain micronuclei, which can lead to genomic change and chromothripsis. In this chapter we describe how to induce checkpoint adaptation and detect it by time-lapse video and immunofluorescence microscopy and how to isolate cells undergoing checkpoint adaptation from a tota作者: molest 時間: 2025-3-23 12:23
A Role for Retrotransposons in Chromothripsisf chromosomes. Following chromosomal shattering, DNA fragments are stitched together in a seemingly random manner resulting in complex genomic rearrangements including sequence shuffling, deletions, and inversions of varying size. This genomic catastrophe has been observed in cancer genomes and the 作者: 聯(lián)邦 時間: 2025-3-23 14:37 作者: SUE 時間: 2025-3-23 18:21 作者: Ceramic 時間: 2025-3-24 01:53
Study of Telomere Dysfunction in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instabilitydysfunction genomically, cellularly, and chromosomally, respectively. We used these approaches to study association between telomere dysfunction and degree of genomic instability related to TP53 mutations in LoVo isogenic cell lines. We found a strong correlation between degree of genomic instabilit作者: Arbitrary 時間: 2025-3-24 04:05 作者: 非實體 時間: 2025-3-24 08:23
Book 2018 Beginning with a section exploring the genesis and impact of chromothripsis, the collection continues by covering the identification of chromothripsis, the causal mechanisms of chromothripsis, the bioinformatics tools for chromothripsis analysis, and experimental systems recently developed for the 作者: CANE 時間: 2025-3-24 14:33
Clinical Consequences of Chromothripsis and Other Catastrophic Cellular Eventsntroduce representative cases of human disorders arising from somatic or germline chromothripsis or similar catastrophic events. In this chapter, we use the term “chromoanagenesis” to indicate all catastrophic events including chromothripsis.作者: 使人煩燥 時間: 2025-3-24 15:57 作者: 低能兒 時間: 2025-3-24 22:38
Metabolism, Crisis, and Elasticityntroduce representative cases of human disorders arising from somatic or germline chromothripsis or similar catastrophic events. In this chapter, we use the term “chromoanagenesis” to indicate all catastrophic events including chromothripsis.作者: flaunt 時間: 2025-3-25 01:25 作者: gait-cycle 時間: 2025-3-25 04:01
https://doi.org/10.1007/978-1-4842-5581-0ds are also useful in detecting chromothripsis in biopsy samples. Issues related to sample collection, storage, and transport, especially with tumor biopsies, may limit the options for sequencing studies, and in such cases, SNP-based microarray may be a viable alternative for detecting chromothripsis.作者: ARY 時間: 2025-3-25 07:28 作者: 咽下 時間: 2025-3-25 15:18 作者: acrophobia 時間: 2025-3-25 18:36
Metabolism, Crisis, and Elasticity gametogenesis and early embryonic development may contribute to the emergence of chromothripsis. Multiple lines of evidence support the assumption that chromothripsis may arise more frequently than previously thought in both gametogenesis and early human embryogenesis.作者: Silent-Ischemia 時間: 2025-3-25 23:44
Potential Role of Chromothripsis in the Genesis of Complex Chromosomal Rearrangements in Human Gamet gametogenesis and early embryonic development may contribute to the emergence of chromothripsis. Multiple lines of evidence support the assumption that chromothripsis may arise more frequently than previously thought in both gametogenesis and early human embryogenesis.作者: 萬靈丹 時間: 2025-3-26 00:52 作者: superfluous 時間: 2025-3-26 05:36 作者: Conserve 時間: 2025-3-26 10:03 作者: 反復(fù)無常 時間: 2025-3-26 12:49 作者: 漸強 時間: 2025-3-26 20:04 作者: 專橫 時間: 2025-3-26 23:05
Chromothripsis and the Macroevolution Theoryothripsis in species evolution. The occurrence of chromothripsis appears to be in good agreement with macroevolution models proposed as a complement to phyletic gradualism. The emergence of this unexpected phenomenon may help to demonstrate the contribution of chromosome rearrangements to speciation process.作者: deficiency 時間: 2025-3-27 04:51 作者: Deduct 時間: 2025-3-27 07:21 作者: Obliterate 時間: 2025-3-27 09:59
Detection of Impaired DNA Replication and Repair in Micronuclei as Indicators of Genomic Instability micronuclei basic general functions, such as DNA replication and repair. The detection of DNA repair and replication defects in micronuclei is described here, as well as the analysis of chromosome breakage and inaccurate reassembly of broken segments in the daughter cells, as indirect methods to detect chromothripsis.作者: pacific 時間: 2025-3-27 14:31
The Genomic Characteristics and Origin of Chromothripsis result from lagging chromosomes encapsulated in micronuclei, as well as from telomere fusions followed by chromosome bridge formation. In this chapter, we will outline the genomic characteristics of chromothripsis, and we present genomic methodologies that enable the detection of chromothripsis. Fu作者: 烤架 時間: 2025-3-27 21:38 作者: 多產(chǎn)子 時間: 2025-3-27 23:07 作者: palpitate 時間: 2025-3-28 05:27
A Role for Retrotransposons in Chromothripsisthods chapter, I discuss how to apply available bioinformatic tools and the hallmarks of retrotransposon mobilization to breakpoint junctions to assess the role for active and inactive retrotransposon sequences in chromothriptic events.作者: anchor 時間: 2025-3-28 07:35
Genes, Proteins, and Biological Pathways Preventing Chromothripsisipsis occurred after experimental induction of telomere crisis after which dicentric chromosomes sustained TREX1-mediated resolution of chromosome bridges and kataegis. Third, DNA polymerase Polθ-dependent chromothripsis has been documented. Finally, a family with chromothripsis after L1 element-dep作者: Defraud 時間: 2025-3-28 13:43
Engels’s Legacy to Anthropology result from lagging chromosomes encapsulated in micronuclei, as well as from telomere fusions followed by chromosome bridge formation. In this chapter, we will outline the genomic characteristics of chromothripsis, and we present genomic methodologies that enable the detection of chromothripsis. Fu作者: Pert敏捷 時間: 2025-3-28 17:50
https://doi.org/10.1007/978-1-4842-5581-0alities of the chromosome homologues is preserved. Here we describe strategies for working out the organization of highly rearranged genomes by combining SNP array data with various metaphase FISH methods. This approach can also be used to address some of the uncertainties arising from whole genome 作者: 慢跑鞋 時間: 2025-3-28 19:13 作者: 要素 時間: 2025-3-28 23:49 作者: 瑣碎 時間: 2025-3-29 05:09 作者: 墻壁 時間: 2025-3-29 08:04
1064-3745 s and Protocols. serves as a vital resource for cell biologists, molecular biologists, cytogeneticists, and geneticists investigating chromothripsis, but also for students and researchers new to the field of chromothripsis and genomic instability..978-1-4939-9283-6978-1-4939-7780-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Dissonance 時間: 2025-3-29 12:58
Chromothripsis978-1-4939-7780-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: intricacy 時間: 2025-3-29 18:17
https://doi.org/10.1007/978-1-4842-5581-0 this process frequently contain micronuclei, which can lead to genomic change and chromothripsis. In this chapter we describe how to induce checkpoint adaptation and detect it by time-lapse video and immunofluorescence microscopy and how to isolate cells undergoing checkpoint adaptation from a total cell population.作者: Substance 時間: 2025-3-29 21:56 作者: condescend 時間: 2025-3-30 02:18 作者: 河潭 時間: 2025-3-30 05:02 作者: 嘲笑 時間: 2025-3-30 08:45 作者: Apoptosis 時間: 2025-3-30 16:06 作者: Indurate 時間: 2025-3-30 18:58 作者: 沉默 時間: 2025-3-30 21:37 作者: Heresy 時間: 2025-3-31 02:23
