標(biāo)題: Titlebook: Chromosomal Translocations and Genome Rearrangements in Cancer; Janet D. Rowley,Michelle M. Le Beau,Terence H. Rab Book 2015 Springer Inte [打印本頁] 作者: magnify 時間: 2025-3-21 17:34
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer影響因子(影響力)
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer影響因子(影響力)學(xué)科排名
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer網(wǎng)絡(luò)公開度
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer被引頻次
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer被引頻次學(xué)科排名
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer年度引用
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer年度引用學(xué)科排名
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer讀者反饋
書目名稱Chromosomal Translocations and Genome Rearrangements in Cancer讀者反饋學(xué)科排名
作者: debunk 時間: 2025-3-21 23:50
Molecular Genetics Methods in Discovery of Chromosome Structurerom single nucleotide changes to those involving parts of chromosomes or whole chromosomes, likely reflect the many different solutions taken by individual tumours to escape normal growth regulatory mechanisms. A variety of molecular and cytogenetic techniques, differing in resolution and capabiliti作者: 門閂 時間: 2025-3-22 00:40
Mechanisms of Recurrent Chromosomal Translocationsrrent chromosomal translocations are found in various cancers. Recently developed high-throughput approaches to clone genome-wide translocations that involve site-specific DSBs have provided new insights into mechanisms of chromosomal translocations. Such studies confirmed that, beyond cellular sele作者: biosphere 時間: 2025-3-22 07:24 作者: Arresting 時間: 2025-3-22 10:59 作者: FLIT 時間: 2025-3-22 16:04 作者: FLIT 時間: 2025-3-22 17:12 作者: 太空 時間: 2025-3-22 21:18
Immunoglobulin and , Rearrangements in Multiple Myeloma Pathogenesisined significance. Both are characterized by hyperdiploidy and recurrent immunoglobulin gene translocations that all result in the direct or indirect dysregulation of the CCND/RB1 pathway. Analysis of the translocation breakpoints suggests that they most frequently occur as a result of an error duri作者: cyanosis 時間: 2025-3-23 02:13
Chromosomal Translocations in B Cell Lymphomasnant transformation of mature B cells, most commonly at the germinal centre (GC) stage of differentiation. Analogous to most cancer types, these tumours are caused by alterations of oncogenes and tumour suppressor genes, some of which have specific roles in GC development. This chapter will focus on作者: Negligible 時間: 2025-3-23 06:13
Chromosomal Translocations and Gene Rearrangements in Acute Lymphoblastic Leukaemia lymphoid blast cells resembling early B- or T-cell progenitors. ALL occurs as a result of genetic, epigenetic and chromosomal aberrations that lead to unregulated cellular proliferation, a block in lymphocyte differentiation, aberrant cell survival and enhanced self-renewal. Chromosomal lesions can作者: Indent 時間: 2025-3-23 13:04
Acute Promyelocytic Leukaemia: From a Specific Translocation to Cure by Targeted Therapies differentiation by a hormone, retinoic acid (RA), and the miraculous complete remissions that this drug yields in patients. This led to 25 years of extensive molecular explorations of the pathogenesis of this disease, starting with the identification of the retinoic acid receptor alpha (RARA) as th作者: DRILL 時間: 2025-3-23 13:58 作者: hereditary 時間: 2025-3-23 20:32
Fusion Oncogenes of Sarcomasction components and transcription factors. The oncogenes discussed here act as regulators of transcription. FET family and . oncoproteins bind DNA with target gene specificity causing specific tumour types with limited morphological variation. Tumours expressing . fusion proteins show larger morpho作者: DRILL 時間: 2025-3-24 01:56 作者: 免除責(zé)任 時間: 2025-3-24 02:28 作者: 有其法作用 時間: 2025-3-24 08:18
Molecular Genetics Methods in Discovery of Chromosome Structurees for high throughput or single cell analysis, for example, have been used to investigate the altered state of tumour genomes. Some of these methods have become the mainstay of clinical cancer diagnosis and patient management.作者: 共棲 時間: 2025-3-24 12:55
Mechanisms of Recurrent Chromosomal Translocationsction forces, basic mechanistic factors, including DSB frequency and persistence, as well as aspects of three dimensional genome organization, can contribute to recurrent translocations in a cell population. This review discusses our current view of the contribution of such mechanistic factors to recurrent chromosomal translocations.作者: osculate 時間: 2025-3-24 16:51
Chronic Myeloid Leukaemiasuccessful therapeutic advance in CML. In this chapter, we review the implications of BCR-ABL1 signalling in CML, how this knowledge revolutionized CML treatment, and discuss approaches to further improving therapeutic response by the targeting of leukaemic stem cells.作者: 我就不公正 時間: 2025-3-24 22:36
Chromosomal Translocations in B Cell Lymphomas the mechanisms and consequences of chromosomal translocations and other genetic lesions involved in the pathogenesis of the most common types of mature B cell lymphomas, including Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B Cell Lymphoma, and Burkitt Lymphoma.作者: Bouquet 時間: 2025-3-25 02:56 作者: Polydipsia 時間: 2025-3-25 04:33 作者: 熱心助人 時間: 2025-3-25 09:43
Translocations in Ewing Sarcomaing the molecular processes governed by these rearrangements promises to generate immediately actionable therapeutic strategies. This chapter discusses the defining role that translocations and their after-effects play in Ewing sarcoma.作者: 來這真柔軟 時間: 2025-3-25 12:11 作者: 全等 時間: 2025-3-25 18:10
From Social Protection to Social Commons,es for high throughput or single cell analysis, for example, have been used to investigate the altered state of tumour genomes. Some of these methods have become the mainstay of clinical cancer diagnosis and patient management.作者: 救護(hù)車 時間: 2025-3-25 20:59 作者: neutralize 時間: 2025-3-26 00:39
https://doi.org/10.1007/978-3-658-40565-6successful therapeutic advance in CML. In this chapter, we review the implications of BCR-ABL1 signalling in CML, how this knowledge revolutionized CML treatment, and discuss approaches to further improving therapeutic response by the targeting of leukaemic stem cells.作者: 向前變橢圓 時間: 2025-3-26 06:13 作者: scrutiny 時間: 2025-3-26 09:45 作者: Temporal-Lobe 時間: 2025-3-26 14:41 作者: 包租車船 時間: 2025-3-26 17:17 作者: 啟發(fā) 時間: 2025-3-27 00:20 作者: 密碼 時間: 2025-3-27 01:23
Studying Youth and Social Movementsf tumours, the second application has been to correlate the chromosomal abnormalities with various clinical parameters, again resulting in many thousands of publications, although to date the translation of laboratory observations into clinical practice is still not widespread.作者: Harass 時間: 2025-3-27 07:31 作者: 團(tuán)結(jié) 時間: 2025-3-27 13:23 作者: 形上升才刺激 時間: 2025-3-27 14:16
malities and the subsequent cellular consequences. Exploring themes involving oncogenes, such as by chromosomal translocations, other genome rearrangements and somatic mutations, this book is a review of the field of cancer genetics that presages a new era, as whole genome sequencing becomes more ac作者: fertilizer 時間: 2025-3-27 19:39 作者: 審問 時間: 2025-3-28 00:49 作者: Enliven 時間: 2025-3-28 02:19
American Patterns of Work and Retirementulin or T-cell receptor loci, often mediated by RAG-mediated double-strand breaks. Furthermore, we summarise recent findings from genome and transcriptome resequencing of ALLs that have implications for prognosis and targeted therapy.作者: cumber 時間: 2025-3-28 07:43 作者: 心胸開闊 時間: 2025-3-28 13:31
Chromosomal Translocations and Gene Rearrangements in Acute Lymphoblastic Leukaemiaulin or T-cell receptor loci, often mediated by RAG-mediated double-strand breaks. Furthermore, we summarise recent findings from genome and transcriptome resequencing of ALLs that have implications for prognosis and targeted therapy.作者: FLUSH 時間: 2025-3-28 16:11
https://doi.org/10.1007/978-3-319-19983-2Cancer genomes; Chromosomal abnormalities; Chromosomal translocations; Genome rearrangement; Somatic mut作者: Resistance 時間: 2025-3-28 20:01
978-3-319-79292-7Springer International Publishing Switzerland 2015作者: TIGER 時間: 2025-3-28 23:30 作者: Bucket 時間: 2025-3-29 03:54
http://image.papertrans.cn/c/image/226336.jpg作者: angina-pectoris 時間: 2025-3-29 09:11 作者: CRAFT 時間: 2025-3-29 12:22
From Social Protection to Social Commons,rom single nucleotide changes to those involving parts of chromosomes or whole chromosomes, likely reflect the many different solutions taken by individual tumours to escape normal growth regulatory mechanisms. A variety of molecular and cytogenetic techniques, differing in resolution and capabiliti作者: Ingrained 時間: 2025-3-29 18:14
Redefining the Agenda for Social Justicerrent chromosomal translocations are found in various cancers. Recently developed high-throughput approaches to clone genome-wide translocations that involve site-specific DSBs have provided new insights into mechanisms of chromosomal translocations. Such studies confirmed that, beyond cellular sele作者: 噴油井 時間: 2025-3-29 21:01 作者: Spinal-Fusion 時間: 2025-3-30 00:28
https://doi.org/10.1057/9780230554689s that partially inhibit DNA synthesis, inducing replication stress. The common fragile sites (CFS) are numerous in the human genome, and are essentially observed in all individuals. Although the molecular basis for chromosome fragility of CFSs remains incompletely understood, there is now general a作者: 袋鼠 時間: 2025-3-30 07:57 作者: 尊嚴(yán) 時間: 2025-3-30 10:34
