標(biāo)題: Titlebook: Chromosomal Instability in Cancer Cells; B. Michael Ghadimi,Thomas Ried Book 2015 Springer International Publishing Switzerland 2015 Aneup [打印本頁(yè)] 作者: 拖累 時(shí)間: 2025-3-21 18:27
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells影響因子(影響力)
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells被引頻次
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells被引頻次學(xué)科排名
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells年度引用
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells年度引用學(xué)科排名
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells讀者反饋
書(shū)目名稱(chēng)Chromosomal Instability in Cancer Cells讀者反饋學(xué)科排名
作者: 音樂(lè)學(xué)者 時(shí)間: 2025-3-21 21:56
Recent Results in Cancer Researchhttp://image.papertrans.cn/c/image/226332.jpg作者: Alpha-Cells 時(shí)間: 2025-3-22 03:16
https://doi.org/10.1007/978-3-319-20291-4Aneuploidy; Cancer; DNA Repair; Disease Outcome; Genomic Instability作者: 暫時(shí)中止 時(shí)間: 2025-3-22 04:40
978-3-319-34962-6Springer International Publishing Switzerland 2015作者: 慢跑 時(shí)間: 2025-3-22 11:12 作者: Lipohypertrophy 時(shí)間: 2025-3-22 13:08 作者: Lipohypertrophy 時(shí)間: 2025-3-22 17:11 作者: 臭名昭著 時(shí)間: 2025-3-23 00:27
https://doi.org/10.1007/978-3-658-03994-3hromosomal instability. Telomeres are composed of repetitive DNA sequences (TTAGGG)n in humans, that are bound by specialized telomere binding proteins. Telomeres lose capping function in response to telomere shortening, which occurs during each division of cells that lack telomerase activity—the en作者: 暗諷 時(shí)間: 2025-3-23 02:19 作者: Conduit 時(shí)間: 2025-3-23 06:44
über Wirkung und Wert von Rhetorik consequence of an increased rate of whole chromosome missegregation during mitosis, a process known as chromosomal instability (CIN). In fact, CIN is a hallmark of human cancer and is thought to contribute to tumorigenesis, tumor progression, and the development of therapy resistance by providing a作者: 騷擾 時(shí)間: 2025-3-23 09:53
Auftrittswirkung im Corporate Speakingations and copy number alterations, giving rise to aneuploid karyotypes. The increasing detection of these genetic changes allowed the description of specific tumor entities and the associated patterns of gene expression. In fact, tumor-specific landscapes of gross genomic copy number changes, inclu作者: BARK 時(shí)間: 2025-3-23 16:38 作者: 腫塊 時(shí)間: 2025-3-23 20:12
Stephan Habscheid,Edelgard Vacekon types range from small substitutions to large structural genomic rearrangements, including complex reshuffling of the genome. Sets of mutations in individual cancer genomes may show specific signatures, which can be provoked by both exogenous and endogenous forces. One of the most remarkable muta作者: OTTER 時(shí)間: 2025-3-23 23:12 作者: Ossification 時(shí)間: 2025-3-24 04:06
Book 2015dy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification..作者: Detain 時(shí)間: 2025-3-24 09:10 作者: 外觀 時(shí)間: 2025-3-24 10:48 作者: BYRE 時(shí)間: 2025-3-24 16:34
Stephan Habscheid,Edelgard Vacekn genome structure as opposed to a gradual process of mutation and selection. This chapter focuses on the origin, prevalence and impact of chromothripsis and related complex genomic rearrangements during cancer development.作者: 詼諧 時(shí)間: 2025-3-24 21:12 作者: antedate 時(shí)間: 2025-3-25 00:20
Causes of Chromosomal Instability,cer cells exhibiting CIN. Examples include, for instance, weakened spindle checkpoint signaling, supernumerary centrosomes, defects in chromatid cohesion, abnormal kinetochore-microtubule attachments and increased spindle microtubule dynamics. Here, the mechanisms leading to CIN in human cancer cells are summarized.作者: BOGUS 時(shí)間: 2025-3-25 04:07 作者: 弓箭 時(shí)間: 2025-3-25 10:08 作者: FATAL 時(shí)間: 2025-3-25 14:54 作者: RALES 時(shí)間: 2025-3-25 18:48
Book 2015f strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for th作者: V洗浴 時(shí)間: 2025-3-25 20:06 作者: 外露 時(shí)間: 2025-3-26 03:09
https://doi.org/10.1007/978-3-658-03994-3 and to the initiation of tumors, however, initiated tumors need to reactivate telomerase in order to stabilize chromosomes and to gain immortal growth capacity. In this review, we summarize current knowledge on the role of telomeres in the maintenance of chromosomal stability and carcinogenesis.作者: 合法 時(shí)間: 2025-3-26 08:12
Auftrittswirkung im Corporate Speakingecular characterization of cytogenetic abnormalities has provided insights into the mechanisms of tumorigenesis and has, in a few instances, led to the clinical implementation of effective diagnostic and prognostic tools, as well as treatment strategies that target a specific genetic abnormality.作者: progestogen 時(shí)間: 2025-3-26 10:26
über Wirkung und Wert von Rhetorikand physiology. This chapter focuses on the current understanding of how the yeast . . responds to the acquisition of extra chromosomes and highlights how studies in aneuploid yeasts provide insights onto the effects of aneuploidy in human cells.作者: 沖擊力 時(shí)間: 2025-3-26 16:24 作者: Inscrutable 時(shí)間: 2025-3-26 17:17 作者: QUAIL 時(shí)間: 2025-3-26 22:20
Telomere Dysfunction, Chromosomal Instability and Cancer, and to the initiation of tumors, however, initiated tumors need to reactivate telomerase in order to stabilize chromosomes and to gain immortal growth capacity. In this review, we summarize current knowledge on the role of telomeres in the maintenance of chromosomal stability and carcinogenesis.作者: 下船 時(shí)間: 2025-3-27 03:36
Patterns of Chromosomal Aberrations in Solid Tumors,ecular characterization of cytogenetic abnormalities has provided insights into the mechanisms of tumorigenesis and has, in a few instances, led to the clinical implementation of effective diagnostic and prognostic tools, as well as treatment strategies that target a specific genetic abnormality.作者: 長(zhǎng)處 時(shí)間: 2025-3-27 05:26
Yeast as Models of Mitotic Fidelity,and physiology. This chapter focuses on the current understanding of how the yeast . . responds to the acquisition of extra chromosomes and highlights how studies in aneuploid yeasts provide insights onto the effects of aneuploidy in human cells.作者: bile648 時(shí)間: 2025-3-27 13:06 作者: languor 時(shí)間: 2025-3-27 14:04
0080-0015 f cancer patients.Written by acknowledged experts in the fie.This issue of .Recent Results in Cancer Research. presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer 作者: Gleason-score 時(shí)間: 2025-3-27 19:06 作者: 改進(jìn) 時(shí)間: 2025-3-27 22:30
DNA Repair and Chromosomal Translocations,y. The non-homologous end-joining repair (NHEJ) pathways seem to play the major role in the generation of chromosomal translocations. The “l(fā)andscape” of chromosomal translocation identified in malignancies is largely due to selection processes which operate on the growth advantages conveyed to the c作者: happiness 時(shí)間: 2025-3-28 02:27 作者: 攤位 時(shí)間: 2025-3-28 07:46 作者: malign 時(shí)間: 2025-3-28 11:24 作者: Shuttle 時(shí)間: 2025-3-28 17:42 作者: 一個(gè)攪動(dòng)不安 時(shí)間: 2025-3-28 19:25
Patterns of Chromosomal Aberrations in Solid Tumors,ations and copy number alterations, giving rise to aneuploid karyotypes. The increasing detection of these genetic changes allowed the description of specific tumor entities and the associated patterns of gene expression. In fact, tumor-specific landscapes of gross genomic copy number changes, inclu作者: CRAMP 時(shí)間: 2025-3-28 22:59
Yeast as Models of Mitotic Fidelity, haploid number. Aneuploidy is associated with human diseases including mental retardation, neurodegenerative diseases and cancer. In addition, aneuploidy is the major cause of spontaneous abortions and its occurrence increases with aging. Therefore, it is important to understand the molecular mecha作者: Abduct 時(shí)間: 2025-3-29 05:32
The Diverse Effects of Complex Chromosome Rearrangements and Chromothripsis in Cancer Development,on types range from small substitutions to large structural genomic rearrangements, including complex reshuffling of the genome. Sets of mutations in individual cancer genomes may show specific signatures, which can be provoked by both exogenous and endogenous forces. One of the most remarkable muta
