標題: Titlebook: Chromosomal Alterations; Methods, Results and Günter Obe,Vijayalaxmi Book 2007 Springer-Verlag Berlin Heidelberg 2007 Aberrationen, chromos [打印本頁] 作者: 佯攻 時間: 2025-3-21 19:22
書目名稱Chromosomal Alterations影響因子(影響力)
書目名稱Chromosomal Alterations影響因子(影響力)學科排名
書目名稱Chromosomal Alterations網(wǎng)絡(luò)公開度
書目名稱Chromosomal Alterations網(wǎng)絡(luò)公開度學科排名
書目名稱Chromosomal Alterations被引頻次
書目名稱Chromosomal Alterations被引頻次學科排名
書目名稱Chromosomal Alterations年度引用
書目名稱Chromosomal Alterations年度引用學科排名
書目名稱Chromosomal Alterations讀者反饋
書目名稱Chromosomal Alterations讀者反饋學科排名
作者: cutlery 時間: 2025-3-21 21:45 作者: Ascendancy 時間: 2025-3-22 04:11
Effects of Ultraviolet Radiation on DNA,tant being pyrimidine dimers and the so-called 6-4-photoproduct. The yield of strand breaks is very low directly after exposure, but they may be formed indirectly upon further incubation. Although DNA absorbs only weakly in the UV-A region, it may be damaged indirectly via endogenous photosensitiser作者: notice 時間: 2025-3-22 05:45
Double Strand Break Repair Mechanisms in Mammalian Cells, and repair events or as potentially lethal lesions introduced by ionising radiation or drugs. In any case, DSBs have to be eliminated immediately, because of the recombinogenic capacity of the DNA ends generated by the DSB that increases the risk for undesired chromosomal aberrations (CAs). In orde作者: dainty 時間: 2025-3-22 10:49
Backup Pathways of Nonhomologous End Joining May Have a Dominant Role in the Formation of ChromosomThey have been directly implicated in cell killing, mutation induction and oncogenic transformation and have spearheaded a great number of investigations focused on their qualitative and quantitative analysis. The central aim of modern cytogenetics is the description at the molecular level of the ob作者: Urologist 時間: 2025-3-22 16:28 作者: Urologist 時間: 2025-3-22 17:35 作者: LURE 時間: 2025-3-22 22:06
Adducts, Sister-Chromatid Exchanges and Mutations Following Benzo[,]pyrene Exposure: a Review of Quion of sister-chromatid exchanges (SCE) and mutations following benzo[.]pyrene (BaP) exposure. Mean adduct levels per dose unit after exposure in vitro were higher in both human (11 studies) and animal (five studies) cells for doses below 5?μM (2.47 and 1.445 adducts per 10. nucleotides per μM, resp作者: CESS 時間: 2025-3-23 03:44 作者: Indebted 時間: 2025-3-23 06:11
Comet Assay,n. The comet assay can be applied to all cells, tissues and organs as long as it is possible to generate single cells. The concept of the assay is comparatively simple. In order to study DNA damage either directly after exposure to an agent or after repair has taken place, single cells are placed in作者: Delectable 時間: 2025-3-23 13:41 作者: 高度贊揚 時間: 2025-3-23 14:44 作者: 飛鏢 時間: 2025-3-23 19:01 作者: 發(fā)微光 時間: 2025-3-23 23:05
A Biomedical Perspective of Telomere Structure and Function,rial within the cell, preventing its exonucleolytic degradation, end-to-end fusions and other chromosome-lethal events. Interest in this multifunctional chromosome segment has increased considerably since it intervenes in cell senescence, gene transcriptional regulation, premature aging syndromes an作者: emulsify 時間: 2025-3-24 04:33 作者: 貪婪地吃 時間: 2025-3-24 08:04 作者: Axillary 時間: 2025-3-24 11:38
Sister-Chromatid Exchanges,to detect SCEs cells must be either treated with the label for one round of replication prior to treatment with the mutagen studied or treated simultaneously, but fixed and harvested following two rounds of replication. Thus, one can never be sure if the label (usually 5-bromo-2′-deoxyuridine, BrdU)作者: hidebound 時間: 2025-3-24 15:36 作者: NATTY 時間: 2025-3-24 20:44
The CAB and S&S Systems, and an Approach Towards the Classification of Complex Chromosome Exchanges interaction between three or more breaks in two or more chromosomes, i.e. they are actually “complex exchanges”. This is not obvious from the usual solid-staining methods, so nomenclature, scoring systems and theory have developed on the assumption that two-break exchanges are the norm. Such system作者: FECK 時間: 2025-3-25 03:11
https://doi.org/10.1007/978-3-642-88062-9amaged DNA sites, predominantly damaged bases, single-stand breaks, double-strand breaks and DNA–protein cross-links. Molecular oxygen enhances and thiols reduce the severity of the DNA damage. The mechanisms leading to these lesions are discussed in the light of our present knowledge of the underlying free-radical chemistry.作者: 大火 時間: 2025-3-25 05:10 作者: 小卷發(fā) 時間: 2025-3-25 10:55
Book 2007dosimetry in radiation accidents and in astronauts and as a predictive measure of cancer are topics discussed in this book. The book will help the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discusse作者: 不可接觸 時間: 2025-3-25 13:31 作者: 喪失 時間: 2025-3-25 15:48
Red Cell Structure and Its Breakdown,he culture medium. In this chapter we review the evidence for targeted and non-targeted induction of chromosomal rearrangements after exposure to ionizing radiation and speculate about potential mechanisms and their significance in radiation risk assessment.作者: observatory 時間: 2025-3-25 21:58 作者: kyphoplasty 時間: 2025-3-26 00:12 作者: GEM 時間: 2025-3-26 05:48
Sister-Chromatid Exchanges,n culture do not grow in a synchronized manner, perturbations of the cell cycle kinetics provide a potential source of error in estimating the true SCE frequency. The aim of this chapter is to discuss some problems of the SCE assay, especially those related to the use of BrdU.作者: Synapse 時間: 2025-3-26 09:42
s and as a predictive measure of cancer.Written by respected.Cytogenetics is a very important research tool in basic and applied research. The uses of cytogenetics in human-population monitoring, in biological dosimetry in radiation accidents and in astronauts and as a predictive measure of cancer a作者: 憤慨一下 時間: 2025-3-26 13:30
DNA Lesions Induced by Ionizing Radiation,amaged DNA sites, predominantly damaged bases, single-stand breaks, double-strand breaks and DNA–protein cross-links. Molecular oxygen enhances and thiols reduce the severity of the DNA damage. The mechanisms leading to these lesions are discussed in the light of our present knowledge of the underlying free-radical chemistry.作者: 引起痛苦 時間: 2025-3-26 19:25 作者: 不如樂死去 時間: 2025-3-26 23:38 作者: 偏見 時間: 2025-3-27 02:25
http://image.papertrans.cn/c/image/226330.jpg作者: magnate 時間: 2025-3-27 09:03 作者: 流動性 時間: 2025-3-27 11:44
https://doi.org/10.1007/978-3-642-88062-9ng it (“indirect effect,” mainly owing to the formation of ?OH radicals). These ionization events induce a series of free-radical reactions that eventually show up in biological end points such as mutations and reproductive cell death. Precursors of these biological end points are various kinds of d作者: abysmal 時間: 2025-3-27 16:25 作者: 打算 時間: 2025-3-27 19:48
https://doi.org/10.1007/978-3-642-88062-9 and repair events or as potentially lethal lesions introduced by ionising radiation or drugs. In any case, DSBs have to be eliminated immediately, because of the recombinogenic capacity of the DNA ends generated by the DSB that increases the risk for undesired chromosomal aberrations (CAs). In orde作者: 或者發(fā)神韻 時間: 2025-3-28 00:46 作者: 一罵死割除 時間: 2025-3-28 02:25
Red Cell Structure and Its Breakdown,energy in the nucleus of the irradiated cell causing DNA double-strand cleavage and the failure of the DNA repair machinery to faithfully restore the integrity of the genetic material. There is also increasing evidence that an irradiated cell can signal to a non-irradiated “bystander” cell and elici作者: 騙子 時間: 2025-3-28 06:50
Protoplasmatologia‘ Cell Biology Monographseing used in cancer therapy. Methylating agents attack DNA at 13 sites. The main mutagenic and carcinogenic DNA lesion is .-methylguanine, whereas both N-methylation lesions and .-methylguanine contribute to sister-chromatid exchanges, chromosomal aberrations and cell death. The contribution depends作者: 輕率的你 時間: 2025-3-28 12:30
Triggers for the Transfusion of Red Cells,ion of sister-chromatid exchanges (SCE) and mutations following benzo[.]pyrene (BaP) exposure. Mean adduct levels per dose unit after exposure in vitro were higher in both human (11 studies) and animal (five studies) cells for doses below 5?μM (2.47 and 1.445 adducts per 10. nucleotides per μM, resp作者: 不易燃 時間: 2025-3-28 14:50
https://doi.org/10.1007/978-1-4612-1798-5 cells damaged with DSB-inducing agents. The H2A histone variant, H2AX, becomes phosphorylated by the phosphatidylinositol 3-kinase-like protein kinases, ATM and ATR, within 1–3 min after ?-irradiation. The phosphorylated form, called ?-H2AX, can be visualised as discrete foci with the use of specif作者: 加強防衛(wèi) 時間: 2025-3-28 21:46 作者: 一美元 時間: 2025-3-29 00:58 作者: 合適 時間: 2025-3-29 03:12 作者: 傳授知識 時間: 2025-3-29 07:24
Atmospheric Circulation and Climate,the role of chromatin structure and remodelling in the formation of double-strand breaks and their processing into chromosome damage. Open chromatin conformation, recognized as euchromatin, possesses transcriptional activity, while tighter chromatin conformation, named heterochromatin, remains trans作者: 平項山 時間: 2025-3-29 12:37
Constructing the Export Infrastructure,rial within the cell, preventing its exonucleolytic degradation, end-to-end fusions and other chromosome-lethal events. Interest in this multifunctional chromosome segment has increased considerably since it intervenes in cell senescence, gene transcriptional regulation, premature aging syndromes an作者: 祖先 時間: 2025-3-29 15:41 作者: gnarled 時間: 2025-3-29 19:42 作者: JOT 時間: 2025-3-30 01:45
Structure and Evolution of the Milky Wayto detect SCEs cells must be either treated with the label for one round of replication prior to treatment with the mutagen studied or treated simultaneously, but fixed and harvested following two rounds of replication. Thus, one can never be sure if the label (usually 5-bromo-2′-deoxyuridine, BrdU)作者: 藕床生厭倦 時間: 2025-3-30 07:29 作者: 和平 時間: 2025-3-30 10:49 作者: 必死 時間: 2025-3-30 12:48 作者: 云狀 時間: 2025-3-30 17:30
978-3-642-09059-2Springer-Verlag Berlin Heidelberg 2007作者: 表兩個 時間: 2025-3-30 20:56 作者: prick-test 時間: 2025-3-31 01:22 作者: 廣口瓶 時間: 2025-3-31 07:56 作者: animated 時間: 2025-3-31 11:04 作者: GLIDE 時間: 2025-3-31 13:47
Nomenclature of Red Cell Shapes A commentarynt pathways are predominantly responsible for the initial removal of the majority of DSBs from the genome. From the homologyindependent pathways, both DNA-PK-dependent nonhomologous end joining (D-NHEJ) and backup nonhomologous end joining (B-NHEJ) have the potential of forming chromosome aberration作者: 容易生皺紋 時間: 2025-3-31 18:07
Triggers for the Transfusion of Red Cells,d animal cells for doses below 5?μM BaP (1.48 and 13.32 SCEs per cell per μM, respectively) than for doses of 5?μM and above (0.18 and 0.97 SCEs per cell per μM). In human cells in vitro (three studies, all below 5?μM) a non-significant downward trend in mutation frequency per dose unit with increas作者: 東西 時間: 2025-4-1 01:45
https://doi.org/10.1007/978-1-4612-1798-5 DNA to various repair factors which are colocalised in the foci. The foci are dispensable for the initial recruitment of proteins and for the early repair and signalling events. Afterwards, however, foci are needed to concentrate and retain the repair proteins in the vicinity of DSB. This seems to 作者: cochlea 時間: 2025-4-1 05:25 作者: MUT 時間: 2025-4-1 09:13
