標題: Titlebook: Cholinergic Basis for Alzheimer Therapy; Robert Becker,Ezio Giacobini Book 1991 Springer Science+Business Media New York 1991 Alzheimer‘‘s [打印本頁] 作者: 葉子 時間: 2025-3-21 19:55
書目名稱Cholinergic Basis for Alzheimer Therapy影響因子(影響力)
書目名稱Cholinergic Basis for Alzheimer Therapy影響因子(影響力)學科排名
書目名稱Cholinergic Basis for Alzheimer Therapy網(wǎng)絡公開度
書目名稱Cholinergic Basis for Alzheimer Therapy網(wǎng)絡公開度學科排名
書目名稱Cholinergic Basis for Alzheimer Therapy被引頻次
書目名稱Cholinergic Basis for Alzheimer Therapy被引頻次學科排名
書目名稱Cholinergic Basis for Alzheimer Therapy年度引用
書目名稱Cholinergic Basis for Alzheimer Therapy年度引用學科排名
書目名稱Cholinergic Basis for Alzheimer Therapy讀者反饋
書目名稱Cholinergic Basis for Alzheimer Therapy讀者反饋學科排名
作者: Intellectual 時間: 2025-3-21 22:43
978-1-4899-6740-4Springer Science+Business Media New York 1991作者: 詳細目錄 時間: 2025-3-22 01:13
,Grunds?tze der ordnungsm??igen Buchführung,any major subcortical structures important to information processing (Whitehouse et al 1982). Initially the pathological findings of deficient cholinergic activity were used to support a hypothesis that the cholinergic loss was an etiologic or pathogenetic factor in the development of the anatomical作者: 坦白 時間: 2025-3-22 04:43 作者: Cougar 時間: 2025-3-22 08:50 作者: CAND 時間: 2025-3-22 13:03
https://doi.org/10.1007/978-3-8349-9780-7cycles, arousal and attentiveness (see Steriade and Buzsaki, 1990). Thus, a breakdown of central cholinergic transmission which can be observed in various mental disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and post-alcoholic Korsakoff s disease (KD) might play an important r作者: CAND 時間: 2025-3-22 20:00 作者: 搜集 時間: 2025-3-22 23:31
,Grunds?tze der ordnungsm??igen Buchführung,tion may prove palliative in the treatment of Alzheimer’s disease. Use of selective acetylcholinesterase (AChE) inhibitors which are retained within the central nervous system is one widely considered approach. An alternative approach would be regulation of expression of proteins critical to choline作者: 起草 時間: 2025-3-23 02:29
Die Rechnungslegung von Bistümern im Wandels, neostigmine, pyridostigmine and edrophonium are all quaternary ammonium compounds and are used for the reversal of neuromuscular blockade following anesthesia and in patients with myasthenia gravis (Aquilonius and Hartvig, 1988). The centrally acting compounds physostigmine and 1,2,3,4-tetrahydro作者: 誘使 時間: 2025-3-23 05:56
Die Durchführung von Inventurent of acetylcholinesterase (AChE) inhibition. It provokes in turn several simultaneous processes (sustained postsynaptic depolarization, postsynaptic potentiation, desensitization, alterations in presynaptic transmitter release etc.) which affect transmission through cholinergic synapses. But the tot作者: 滔滔不絕的人 時間: 2025-3-23 09:48
Bj?rn Blankschyn,Fabian G?ppert in rat brain (Molenaar and Polak, 1970; Marchi et al., 1981). A muscarinic receptor mediated mechanism similar to that present in the rodent was proposed to exist, on the basis of indirect evidence, also in human brain (Marek et al., 1982; Nordstrom et al., 1982; Nilsson et al., 1987).作者: 無辜 時間: 2025-3-23 15:39 作者: collateral 時間: 2025-3-23 21:39 作者: Brittle 時間: 2025-3-24 01:43 作者: 低三下四之人 時間: 2025-3-24 02:58 作者: cluster 時間: 2025-3-24 10:22 作者: 臨時抱佛腳 時間: 2025-3-24 10:41
Presynaptic Cholinergic Mechanisms in Human Cerebral Cortex of Adult and Aged Patients in rat brain (Molenaar and Polak, 1970; Marchi et al., 1981). A muscarinic receptor mediated mechanism similar to that present in the rodent was proposed to exist, on the basis of indirect evidence, also in human brain (Marek et al., 1982; Nordstrom et al., 1982; Nilsson et al., 1987).作者: Interlocking 時間: 2025-3-24 15:07 作者: Harass 時間: 2025-3-24 22:04 作者: PALSY 時間: 2025-3-25 02:52 作者: 事情 時間: 2025-3-25 03:20
Kinetics and Mechanisms of Reversible and Progressive Inhibition of AcetylcholinesteraseThis paper concerns the interaction of reversible ligands, particularly oximes, with acetylcholinesterase (AChE) and their effect upon the catalytic properties of the enzyme.作者: entitle 時間: 2025-3-25 07:51
Immunocytochemistry of Muscarinic and Nicotinic Receptors in Human BrainThis chapter is concerned with recent efforts to visualize nicotinic and muscarinic acetylcholine receptors (nAChRs, mAChRs) in the human brain on the cellular and subcellular level by means of immunocytochemistry.作者: Harbor 時間: 2025-3-25 12:35 作者: 熔巖 時間: 2025-3-25 19:13
Overview: 978-1-4899-6740-4978-1-4899-6738-1作者: 清澈 時間: 2025-3-25 21:41 作者: placebo-effect 時間: 2025-3-26 03:42 作者: 使人煩燥 時間: 2025-3-26 08:03
https://doi.org/10.1007/978-3-8349-8523-1romuscular junction, in autonomic ganglia and in several areas of the brain. The activation of AChR by the acetylcholine (ACh) released from nerve terminals induces an influx of cations, mainly Na. ions, through the cell membrane, consequently depolarizing the target cell.作者: 嬉耍 時間: 2025-3-26 11:55
Structure-Function Relationship Studies in Human Cholinesterases as an Approach for Evaluating Potenely depend on their inhibitory effects on CHEs in the treated individuals. Therefore, updated evaluation methods for these parameters should be valuable to pharmacological research focused on the development and use of cholinergic drugs.作者: Genteel 時間: 2025-3-26 16:32 作者: Inexorable 時間: 2025-3-26 20:37 作者: 粘連 時間: 2025-3-26 23:02 作者: Matrimony 時間: 2025-3-27 03:00
Die Rechnungslegung von Bistümern im Wandeliseases. Renewed interest in the centrally active drugs has arisen following positive reports on symptom alleviation in patients with different types of dementia (Summers et al., 1986, for review see H?kansson, 1990).作者: antiandrogen 時間: 2025-3-27 08:43
Rechnungslegung nach IFRS klipp & klardemonstrated in animals with such lesions. Evidence can be cited for spontaneous, as well as experimentally induced recovery. Recovery from nbM lesions, and basal forebrain cholinergic systems can most readily be induced experimentally. In general, recovery has been induced by pharmacological or neurotrophic means.作者: 制度 時間: 2025-3-27 11:29 作者: uncertain 時間: 2025-3-27 14:40
Clinical Pharmacokinetics of Centrally Acting Cholinesterase Inhibitorsiseases. Renewed interest in the centrally active drugs has arisen following positive reports on symptom alleviation in patients with different types of dementia (Summers et al., 1986, for review see H?kansson, 1990).作者: Insul島 時間: 2025-3-27 19:56
Nucleus Basalis Lesions and Recoverydemonstrated in animals with such lesions. Evidence can be cited for spontaneous, as well as experimentally induced recovery. Recovery from nbM lesions, and basal forebrain cholinergic systems can most readily be induced experimentally. In general, recovery has been induced by pharmacological or neurotrophic means.作者: Ischemia 時間: 2025-3-27 23:27 作者: maculated 時間: 2025-3-28 04:10 作者: exclamation 時間: 2025-3-28 09:44
,überblick über die Steuerarten,ely depend on their inhibitory effects on CHEs in the treated individuals. Therefore, updated evaluation methods for these parameters should be valuable to pharmacological research focused on the development and use of cholinergic drugs.作者: 步兵 時間: 2025-3-28 11:53
Therapy of the Cognitive Deficit in Alzheimer’s Disease: The Cholinergic Systemany major subcortical structures important to information processing (Whitehouse et al 1982). Initially the pathological findings of deficient cholinergic activity were used to support a hypothesis that the cholinergic loss was an etiologic or pathogenetic factor in the development of the anatomical作者: 來就得意 時間: 2025-3-28 15:37 作者: Cpap155 時間: 2025-3-28 21:54
Cholinesterases in Human Degenerative Diseasesese disorders is Alzheimer’s disease (AD). In AD there is a degeneration of projections from the cholinergic basal forebrain to the neocortex and hippocampus resulting in a loss of cell bodies in the basal forebrain and reduced cortical choline acetyltransferase and acetylcholinesterase (AChE) enzym作者: curriculum 時間: 2025-3-29 01:34 作者: 消音器 時間: 2025-3-29 06:24 作者: 哥哥噴涌而出 時間: 2025-3-29 11:10
Structure of the Acetylcholinesterase Gene: Regulation of Its Expressiontion may prove palliative in the treatment of Alzheimer’s disease. Use of selective acetylcholinesterase (AChE) inhibitors which are retained within the central nervous system is one widely considered approach. An alternative approach would be regulation of expression of proteins critical to choline作者: 別名 時間: 2025-3-29 11:34 作者: 慌張 時間: 2025-3-29 17:52 作者: 常到 時間: 2025-3-29 23:03
Presynaptic Cholinergic Mechanisms in Human Cerebral Cortex of Adult and Aged Patients in rat brain (Molenaar and Polak, 1970; Marchi et al., 1981). A muscarinic receptor mediated mechanism similar to that present in the rodent was proposed to exist, on the basis of indirect evidence, also in human brain (Marek et al., 1982; Nordstrom et al., 1982; Nilsson et al., 1987).作者: 包裹 時間: 2025-3-29 23:56
Nicotinic Acetylcholine Receptors in the Human Nervous Systemromuscular junction, in autonomic ganglia and in several areas of the brain. The activation of AChR by the acetylcholine (ACh) released from nerve terminals induces an influx of cations, mainly Na. ions, through the cell membrane, consequently depolarizing the target cell.作者: Blood-Vessels 時間: 2025-3-30 04:52 作者: conspicuous 時間: 2025-3-30 11:14
Nucleus Basalis Lesions and Recovery of research effort has been directed towards strategies to affect recovery from the consequences of cholinergic deficits. Nucleus basalis of Meynert (nbM) lesions in non-human mammals have been found to consistently produce dramatic deficits in cortical cholinergic marker activity, as well as profo作者: 蹣跚 時間: 2025-3-30 13:36
Experimental Automimmune Dementia (EAD): An Immunological Model of Memory Dysfunction and Alzheimer’of immunological mechanisms in the cholinergic degeneration in AD, which include the demonstration of antibodies to such neurons in the sera and cerebrospinal fluid of AD patients (Fillet et al., 1985; Chapman et al., 1986; McRae-Degueurce et al., 1987; Foley et al., 1988). Whether these anti cholin作者: Vertebra 時間: 2025-3-30 17:20
https://doi.org/10.1007/978-3-8349-9780-7animal experiments using stimulation, acute and chronic lesion techniques as well as pharmacological manipulations of cholinergic neurotransmission (see Steriade and Buzsaki, 1990). The primary significance of research concerned with the “cholinergic hypothesis” is based upon the presumption that gr作者: aviator 時間: 2025-3-30 22:08
,Grunds?tze der ordnungsm??igen Buchführung,ystem (Layer and Sporns, 1987) and in the maintenance of synaptic and heterologous cell contacts (DeLa Escalera et al., 1990). Thus, a rational approach to therapeutic intervention in Alzheimer’s disease requires a detailed knowledge of the potential target. Recombinant DNA technology should prove u作者: 空氣傳播 時間: 2025-3-31 00:59
Die Durchführung von Inventurenity to affect not only AChE but various physiologically significant macromolecules (receptors, channels, enzymes etc). Naturally, a number of factors determining the overall effect of inhibitor application and their contribution depend greatly on dose (concentration) of drug.作者: 思鄉(xiāng)病 時間: 2025-3-31 07:43 作者: fatty-acids 時間: 2025-3-31 10:04
The Pathology of the Human Nucleus Basalis of Meynert and its Implications for a Specific Therapyanimal experiments using stimulation, acute and chronic lesion techniques as well as pharmacological manipulations of cholinergic neurotransmission (see Steriade and Buzsaki, 1990). The primary significance of research concerned with the “cholinergic hypothesis” is based upon the presumption that gr作者: CRANK 時間: 2025-3-31 13:33 作者: ARIA 時間: 2025-3-31 17:40
Pre- and Postsynaptic Effects of Cholinesterase Inhibitorsity to affect not only AChE but various physiologically significant macromolecules (receptors, channels, enzymes etc). Naturally, a number of factors determining the overall effect of inhibitor application and their contribution depend greatly on dose (concentration) of drug.作者: 赦免 時間: 2025-4-1 01:05
Nicotinic Receptors in the CNS as Visualized by Positron Emission Tomographyholine acetyltransferase activity, synthesis and release of acetylcholine and nicotinic receptors. Positron emission tomography (PET) is a technique suitable for . studies of neuronal activity in the brain. PET has already shown a great potential for psychopharmacological research. Is it possible to
